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All Journal Dentika Dental Journal Althea Medical Journal Journal of Dentomaxillofacial Science Medicinus : Jurnal Kedokteran Majalah Anestesia dan Critical Care Jurnal Integrasi Kesehatan dan Sains Jurnal Ilmu Faal Olahraga Indonesia Jurnal Riset Kedokteran Bandung Conference Series : Medical Science
Hendro Sudjono Yuwono
Fakultas Kedokteran Universitas Islam Bandung
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Althea Medical Journal

 1 
Factors Influencing the Success Rate of Cardiopulmonary Resuscitation Hanif, Aisyah Amanda; Rachman, Iwan Abdul; Yuwono, Hendro Sudjono
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (553.013 KB)

Abstract

Background: Cardiopulmonary resuscitation (CPR) is a series of actions performed on cardiac arrest patients. Not all patients receiving CPR can survive. The outcome of CPR is influenced by several factors. This study was conducted to determine the success rate of CPR and the factors influencing it in Dr. Hasan Sadikin General Hospital in 2013.Methods: This study was conducted by using 168 patient medical records who underwent CPR and met the inclusion criteria in the Resuscitation Room of Dr. Hasan Sadikin General Hospital from January to December 2013. The collected data consisted of age, gender, pre-arrest diagnosis, initial rhythm, response time and clinical outcome of CPR. The results were expressed in frequencies and percentage. The data were analyzed using the chi-square test.Results: The Success rate of CPR was 15.5%. The success rate was higher in patients with cardiac prearrest diagnoses (8.33%, p=0.024). The most common initial rhythm was unshockable rhythms (83.92%), yet patients with shockable heart rhythms had higher success rates (40.74%, p<0.001). All of the surviving patients had response time within the first minute from cardiac arrest.Conclusions: Success rate of CPR in the resuscitation room of Dr. Hasan Sadikin General Hospital during 2013 is still low. The factors influencing the survival rate are the pre-arrest diagnosis and initial heartrhythm. [AMJ.2015;2(4):615–9] DOI: 10.15850/amj.v2n4.657
Antidiabetic Activity of Calcium Bentonite in Alloxan Monohydrate-induced Diabetic Wistar Rat Models Alviana, Galuh; Yuwono, Hendro Sudjono; Sylviana, Nova
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.583 KB)

Abstract

Background: Calcium bentonite is a natural clay that has the ability to absorb toxins and metabolite excess substances and often referred to as healing clay because it is used traditionally. This study aimed to determine the ability of local calcium bentonite to absorp high blood glucose..Methods: This study was an experimental study using 20 female Wistar rats and divided into two groups consisting of Group I (control group, n=10) and Group II (calcium bentonite group, n=10). Diabetes in rats was induced by alloxan monohydrate 150 mg/kg body weight intraperitoneally. Examination of blood glucose was performed three times; in the beginning of study, 72 hours after alloxan monohydrate induction, and four days after the given interventions. Blood glucose levels in mean values were analyzed using t-independent test. Statistically significance was considered when p<0.05.Results: Oral calcium bentonite of 1g/kg body weight significantly lowered blood glucose level relatively to the control group with average value of 131.30 mg/dl (p=0.01).Conclusions: Calcium bentonite significantly lowers blood glucose levels. DOI: 10.15850/amj.v2n3.562
Effects of Calcium Bentonite on High Blood Cholesterol Level Yuwono, Hendro Sudjono; Tangke, Fadhli Rajif; Farenia, Reni
Althea Medical Journal Vol 5, No 3 (2018)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (655.869 KB) | DOI: 10.15850/amj.v5n3.551

Abstract

Background: Calcium bentonite has been known to decrease high blood cholesterol level. This study aimed to explore whether a local calcium bentonite from West Java, Indonesia, had effect on lowering total blood cholesterol level.Methods: A laboratory experimental study was carried out on thirty adult male  Wistar rats’ at Laboratory animals, Department of Pharmacology and Therapy, Universitas Padjadjaran in 2012. The rats were divided into five groups with six rats in each group, consisting of group I (negative control) with standard diet and distilled water, group II (positive control) with high lipid diet and distilled water, group III with high lipid diet and ezetimibe 0.18 g/rat/day, groups IV with high lipid diet and calcium bentonite 0.25 g/rat/day, group V with high lipid diet and calcium bentonite 0.5 g/rat/day. Ezetimibe as was used as this was an inhibitory agent of intestinal cholesterol absorption. Blood cholesterol levels were measured and analyzed using analysis of variance and Tukey’s post-hoc test.Results: Oral calcium bentonite at 0.25 g/rat/day and 0.5 g/rat/day significantly decrease total blood cholesterol level relative to the positive control group, 31.68% (p=0.018) and 32.87% (p=0.006) respectively, but its effect is inferior to ezetimibe 62.83% (p=0.000).Conclusions: Local calcium bentonite from West Java, Indonesia, has a significant lowering effect, however, the effect is less comparing to ezetimibe.  
Factors Influencing the Success Rate of Cardiopulmonary Resuscitation Aisyah Amanda Hanif; Iwan Abdul Rachman; Hendro Sudjono Yuwono
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (553.013 KB)

Abstract

Background: Cardiopulmonary resuscitation (CPR) is a series of actions performed on cardiac arrest patients. Not all patients receiving CPR can survive. The outcome of CPR is influenced by several factors. This study was conducted to determine the success rate of CPR and the factors influencing it in Dr. Hasan Sadikin General Hospital in 2013.Methods: This study was conducted by using 168 patient medical records who underwent CPR and met the inclusion criteria in the Resuscitation Room of Dr. Hasan Sadikin General Hospital from January to December 2013. The collected data consisted of age, gender, pre-arrest diagnosis, initial rhythm, response time and clinical outcome of CPR. The results were expressed in frequencies and percentage. The data were analyzed using the chi-square test.Results: The Success rate of CPR was 15.5%. The success rate was higher in patients with cardiac prearrest diagnoses (8.33%, p=0.024). The most common initial rhythm was unshockable rhythms (83.92%), yet patients with shockable heart rhythms had higher success rates (40.74%, p<0.001). All of the surviving patients had response time within the first minute from cardiac arrest.Conclusions: Success rate of CPR in the resuscitation room of Dr. Hasan Sadikin General Hospital during 2013 is still low. The factors influencing the survival rate are the pre-arrest diagnosis and initial heartrhythm. [AMJ.2015;2(4):615–9] DOI: 10.15850/amj.v2n4.657
Antidiabetic Activity of Calcium Bentonite in Alloxan Monohydrate-induced Diabetic Wistar Rat Models Galuh Alviana; Hendro Sudjono Yuwono; Nova Sylviana
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.583 KB)

Abstract

Background: Calcium bentonite is a natural clay that has the ability to absorb toxins and metabolite excess substances and often referred to as healing clay because it is used traditionally. This study aimed to determine the ability of local calcium bentonite to absorp high blood glucose..Methods: This study was an experimental study using 20 female Wistar rats and divided into two groups consisting of Group I (control group, n=10) and Group II (calcium bentonite group, n=10). Diabetes in rats was induced by alloxan monohydrate 150 mg/kg body weight intraperitoneally. Examination of blood glucose was performed three times; in the beginning of study, 72 hours after alloxan monohydrate induction, and four days after the given interventions. Blood glucose levels in mean values were analyzed using t-independent test. Statistically significance was considered when p<0.05.Results: Oral calcium bentonite of 1g/kg body weight significantly lowered blood glucose level relatively to the control group with average value of 131.30 mg/dl (p=0.01).Conclusions: Calcium bentonite significantly lowers blood glucose levels. DOI: 10.15850/amj.v2n3.562
Lethal Dose of Calcium Bentonite in Wistar Rats Dwika Audiyananda; Hendro Sudjono Yuwono; Adria Adnan
Althea Medical Journal Vol 8, No 2 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n2.2227

Abstract

Background: Calcium bentonite is a type of clay produced by a devitrification of volcanic ash which is often used as a traditional medicine to absorb toxins and waste products of metabolism. The aim of this study was to determine the lethal dose of calcium bentonite in Wistar rats to explore its toxicity level and safe use.Methods: Fifty male and female Wistar rats were randomly divided into five groups for each sex. The control group was given 5 cc aquadest whereas the other four groups received calcium bentonite solution of 50 mg/kgBW, 300 mg/kgBW, 2,000 mg/kgBW, and 5,000 mg/kgBW, respectively, at a single dose. The weight was observed for up to 7 days and analyzed using the unpaired t-test and Mann-Whitney test. The death rate was calculated using the probit analysis. Median lethal dose results were then classified according to Loomis Criteria. Results: No deaths occurred at the highest dose, suggesting that the median lethal dose value of calcium bentonite was >5,000 mg/kgBW. No weight loss occurred due to the administration of calcium bentonite and a significant increase in the body weight was even observed in the male rat group. Interestingly, a significant decrease was found in the female rats group when compared to the control group.Conclusions: Calcium bentonite is classified as a practically non-toxic material with a median lethal dose of over 5,000 mg/kgBW.
Effects of Calcium Bentonite on High Blood Cholesterol Level Hendro Sudjono Yuwono; Fadhli Rajif Tangke; Reni Farenia
Althea Medical Journal Vol 5, No 3 (2018)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (655.869 KB) | DOI: 10.15850/amj.v5n3.551

Abstract

Background: Calcium bentonite has been known to decrease high blood cholesterol level. This study aimed to explore whether a local calcium bentonite from West Java, Indonesia, had effect on lowering total blood cholesterol level.Methods: A laboratory experimental study was carried out on thirty adult male  Wistar rats’ at Laboratory animals, Department of Pharmacology and Therapy, Universitas Padjadjaran in 2012. The rats were divided into five groups with six rats in each group, consisting of group I (negative control) with standard diet and distilled water, group II (positive control) with high lipid diet and distilled water, group III with high lipid diet and ezetimibe 0.18 g/rat/day, groups IV with high lipid diet and calcium bentonite 0.25 g/rat/day, group V with high lipid diet and calcium bentonite 0.5 g/rat/day. Ezetimibe as was used as this was an inhibitory agent of intestinal cholesterol absorption. Blood cholesterol levels were measured and analyzed using analysis of variance and Tukey’s post-hoc test.Results: Oral calcium bentonite at 0.25 g/rat/day and 0.5 g/rat/day significantly decrease total blood cholesterol level relative to the positive control group, 31.68% (p=0.018) and 32.87% (p=0.006) respectively, but its effect is inferior to ezetimibe 62.83% (p=0.000).Conclusions: Local calcium bentonite from West Java, Indonesia, has a significant lowering effect, however, the effect is less comparing to ezetimibe.  
Co-Authors , Suwarman A. Muthalib Nawawi Abel Tasman Yuza Adria Adnan Aisyah Amanda Hanif Akhmad Fatharoni Andre Akbar Mubarok Daisy Grace Agustina Dhian Indriasari Dicky Santosa Dwika Audiyananda Eddy Hermanto Eka Hendryanny Fadhli Rajif Tangke Galuh Alviana Galuh Alviana, Galuh Ilham Mauludin Ismawati Ismet Muchtar Nur Isnandar Isnandar , Iwan Abdul Rachman Kasman Manullang Kasman Manullang Listya Hanum Siswanti Luthfiyah Salsabilla Mayasari, Ferra Meike Rachmawati Muchtan Sujatno MUCHTAN SUJATNO Muhammad Gibran Al Madani Muhammad Rifky Dzikrillah Muhammad Rifky Dzikrillah Naura Mufida Marsya Naura Mufida Marsya Nova Sylviana Oky Haribudiman Purwaningsih, Sriwahyuniati Reni Farenia Reni Farenia Rifira Hanifah Rizki Perdana Rizky Alifian Ramadhan Saphiera Damayanti Sassty Julya Hidayat Sitanggang, Rully H. Sofyan Al Fauzi Susanti Dharmmika Susanto, Tirta Darmawan Tangke, Fadhli Rajif Tirta Darmawan Susanto Tryando Bhatara Wiwiek Setiowulan