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Comparative Inhibition of Garlic as Natural-Antiseptic and Iodine as Synthetic-Antiseptic against Bacillus subtilis Sazali, Munawir
Proceeding International Conference on Global Resource Conservation Vol 4, No 1: Proceeding of 4th ICGRC 2013
Publisher : Proceeding International Conference on Global Resource Conservation

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Iodine is an antiseptic that often utilized in various antiseptic synthetic trademark types. Nature substance garlic that contains alicin and scordinin are degradation character of membrane cells bacteria. Both of this antiseptics types done research to look at zero zone by Fledged Random Design with three treatment and six repetitions to get data analysis resistive extent each antiseptic into pure breeding Bacillus subtilis. Research method has done with observation, then using analysis ANOVA with analysiss result on checkmates significant 5% and keep on by advanced tests. Result advanced tests points out there is compare zoom that significant of nature and synthetic material, garlic has greater zero zone if compared to Iodine II. Clear zone average of garlic is 6.7 cm and Iodine as big as 3.0 cm. Of this research, result that garlic (Allium sativum) as nature antiseptic could utilize to prevent its happening infection effect of microbe.Keywords: antiseptic, Bacillus subtilis, garlic, Iodine

UJI BEBERAPA DOSIS TRICHOKOMPOS TERHADAP PENYAKIT VIRUS KOMPLEKS, PERTUMBUHAN DAN PRODUKSI TANAMAN CABAI MERAH (Capsicum annuum L.) Sazali, Munawir; Ali, Muhammad
Jurnal Online Mahasiswa (JOM) Bidang Pertanian Vol 4, No 1 (2017): Wisuda Februari Tahun 2017
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Pertanian

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Complex virus disease on red chilli plants is a disease caused by infection of some viruses. The disease can decrease red chilli yield up to 75%. Alternative control method is to induce plant resistance by aplication of Trichoderma sp. which is applied as of Trichocompost. This study aims to study the effect of application of various doses of Trichocompost and obtain the best dose to control the disease and to increase red chilli plant’s growth and yield. This research has been conducted experimentally by using a complete random design consisting of 5 treatments (0, 50, 100, 150 dan 200 g/plant) and 4 replications. The data were analyzed statistically using analysis of variance and the mean of each treatment was compared by using Duncan 's New Multiple Range Test (DNMRT) at level 5%. The results showed that the application of some doses of Trichocompost could induce chilli plant resistance and decrease the intensity of complex virus disease and increase number of fruits and fruit weight. Dose of 150 g/plant gave a better effect in controling complex virus disease as much as 62,62% and increase height of plant, number of fruits and fruit weight. Key words : Red chilli, complex virus, dose Trichocompost, resistance induction

PENDIDIKAN FIQIH BERBASIS KOMPETENSI Sazali, Munawir
Al-Riwayah: Jurnal Kependidikan Vol 8, No 1 (2016): Dinamika
Publisher : STAIN Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32489/al-riwayah.118

Competence is a combination of knowledge, skills, values and attitudes are reflected in the habit of thinking and acting. Such competence can be applied in Fiqh Education. Jurisprudence education includes knowledge, skills and attitudes. Fiqh Education is to know the Islamic law (cognitive), comply with Islamic law (Affective) and implement Islamic law (psychomotor). Fiqh teachers not only give an example, but becomes model. Giving examples and practice means just in front of the class made up. An example means demonstrating good attitude naturally inside and outside the classroom. In this regard, fiqh education is based on understanding aspects. Thus yafqahu activity (understand) is activity of the heart, not just a reason activities, as in al-Qur`an. Whereas in the context of madrasah curriculum, education of fiqh, which is part of the subject of Islamic Education (PAI) is directed to prepare learners to know, understand, appreciate and practice the Islamic law which later became the basis of his outlook on life through counseling, teaching, practice and the use of experience. Thus, fiqh education not only introduces students to law of thing, but also equips skills to implement the law and encourages students to obey the law.

PENDIDIKAN FIQIH BERBASIS KOMPETENSI Sazali, Munawir
Al-Riwayah: Jurnal Kependidikan Vol 8, No 1 (2016): Pendidikan Menurut Al-Quran Dan Hadis
Publisher : STAIN Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32489/al-riwayah.118

Competence is a combination of knowledge, skills, values and attitudes are reflected in the habit of thinking and acting. Such competence can be applied in Fiqh Education. Jurisprudence education includes knowledge, skills and attitudes. Fiqh Education is to know the Islamic law (cognitive), comply with Islamic law (Affective) and implement Islamic law (psychomotor). Fiqh teachers not only give an example, but becomes model. Giving examples and practice means just in front of the class made up. An example means demonstrating good attitude naturally inside and outside the classroom. In this regard, fiqh education is based on understanding aspects. Thus yafqahu activity (understand) is activity of the heart, not just a reason activities, as in al-Qur`an. Whereas in the context of madrasah curriculum, education of fiqh, which is part of the subject of Islamic Education (PAI) is directed to prepare learners to know, understand, appreciate and practice the Islamic law which later became the basis of his outlook on life through counseling, teaching, practice and the use of experience. Thus, fiqh education not only introduces students to law of thing, but also equips skills to implement the law and encourages students to obey the law.

In Silico Analysis of C-Type Lectins as Co-Infection Receptors of Dengue and Chikungunya Viruses in Aedes aegypti Sazali, Munawir; Soesilohadi, R. C. Hidayat; Wijayanti, Nastiti; Wibawa, Tri; Ansori, Arif Nur Muhammad
Makara Journal of Science Vol. 28, No. 1
Publisher : UI Scholars Hub

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Aedes aegypti is a primer vector of dengue virus (DENV) and chikungunya virus (CHIKV). The susceptibility of mosquitoes to DENV and CHIKV depends on their recognition receptor of pathogens. C-type lectins (CTLs) are an important mediator of virus infection in A. aegypti. This study aims to identify potential receptors and determine the binding affinity between ligand–receptor interaction, CTLs and virus envelopes (DENV-1, 2, 3, and 4 and CHIKV) interaction based on in silico analysis. Sample sequences were obtained from GenBank (NCBI), and 10 CTLs were acquired from VectorBase. Homology modeling based on a minimum standard of 20% was processed using the SWISS-MODEL server. Molecule interaction was visualized as tertiary protein structure in PyMol V1.7.4. Homology modeling revealed all 3D protein model scores to be at 20%. The highest homology modeling score of 98.72% is obtained for CHIKV envelope protein (KF925315.1). The CTL GenBank ID: AAEL014382-PA has the lowest score at −1407.20 kcal/mol. The predicted mechanism of DENV-1, 2, 3, and 4 co-infections with CHIKV-1 is through the binding of the viral envelope to the CTL. Interaction analysis showed that the viruses enter through an endocytic mechanism. The results of homology modeling and lowest interaction energy could serve as the basis for in vivo studies on virus co-infection in A. aegypti. This information illustrates that CTL receptors facilitate DENV and CHIKV co-infection in A. aegypti.

PELAKSANAAN KESELAMATAN DAN KESEHATAN KERJA PADA PROYEK GEDUNG RUSUNAWA YAYASAN ALMUSLIM KABUPATEN BIREUEN Sakura, Royanna; Putra, Reza; Masrura, Delfian; Sazali, Munawir
Malikussaleh Journal of Mechanical Science and Technology Vol. 7 No. 2 (2023): Malikussaleh Journal of Mechanical Science and Technology
Publisher : E-Journal Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/mjmst.v7i2.14629

Employment agency such as construction companies must maintain and provide the health of employees, this health comprehensively includes the physical and mental health of workers. Poor worker health can have unfavorable effects for both the worker and the company. Occupational health programs can be carried out by creating a healthy work environment. In the implementation, the occupational health program is always followed by an occupational safety program because the two programs are interrelated in the maintenance of workers. Occupational safety is safety related to the use of the latest technology such as machines, work equipments, materials and processing, the foundation of the place and the environment and steps of the work. Occupational safety and health can help make workers feel comfortable, safe and secure in carrying out the obligations to the company. The purpose of this research was to determine the application of Occupational Safety and Health (OSH) and the comfort level of workers at PT. Wandra Cipta Engineering Consultant in the tenement (Rusunawa) building project of the Almuslim foundation, Bireuen Regency. The research method used in this research was a quantitative method including surveys, questionnaires and interviews while data processing was done by using SPSS software version 25. The results of the research indicated that Occupational Safety and Health (OSH) and the comfort level of workers at PT. Wandra Cipta Engineering Consultant in the tenement (Rusunawa) building project of the Almuslim foundation, Bireuen Regency was very comfortable. This can be seen from the results of data processing on occupational safety and health, it was found that 58.57% of the respondents agreed and the reliability test was 0.724 and 0.843. respectively

Pengaruh Model Pembelajaran Project Based Learning dengan Vidio Animasi Terhadap Kreativitas dan Hasil Belajar Siswa di MTs N 3 Bima Latifah, Nurul; Efendi, M. Harja; Ramlin, Ramlin; Sazali, Munawir
CAHAYA: Journal of Research on Science Education Vol. 3 No. 1 (2025)
Publisher : Alpatih Harapan Semesta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70115/cahaya.v3i1.287

This study aims to analyse the influence of the Project Based Learning model through the creation of animated videos on the creativity and learning outcomes of eighth-grade students at MTsN 3 Bima. This type of research uses a quasi-experimental method with a quantitative approach involving two classes: experimental and control. Data collection was conducted using creativity observation sheets and learning outcome tests that had been validated with the Correl validity test and Cronbach's Alpha reliability test. Data analysis used the Shapiro-Wilk normality prerequisite test, Levene's test for homogeneity, and hypothesis testing using the independent sample t-test with a significance level of 5%. The research results showed a significant effect of the Project Based Learning model on students' creativity and learning outcomes, evidenced by a significance value of 0.000 < 0.05 on both variables. The conclusion of the research proves that the Project Based Learning model can enhance the creativity and learning outcomes of eighth-grade students

Molecular Docking Analysis of Flavonoids from Syzygium cumini (L.) Skeels: Proapoptotic Potential as an Anticancer Mechanism Aini, Nur Sofiatul; Ansori, Arif Nur Muhammad; Widyananda, Muhammad Hermawan; Kharisma, Viol Dhea; Murtadlo, Ahmad Affan Ali; Herdiansyah, Mochammad Aqilah; Rebezov, Maksim; Burkov, Pavel; Gudz, Petr; Derkho, Marina; Bezhinar, Tatyana; Maksimiuk, Nikolai; Sazali, Munawir; Purnobasuki, Hery; Rollando, Rollando; Khairullah, Aswin Rafif; Sucipto, Teguh Hari
Borneo Journal of Pharmacy Vol. 8 No. 3 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i3.9843

Non-small cell lung cancer (NSCLC) presents a significant global health challenge, with its prevalence and mortality rates rising steadily. In Indonesia, Syzygium cumini (L.) Skeels, known for its flavonoid richness, has a long history in traditional medicine. However, its specific mechanisms of action against cancer, particularly in inducing apoptosis in NSCLC, have not been fully elucidated. This study utilized an in silico approach to evaluate the pro-apoptotic potential of S. cumini flavonoids against NSCLC by targeting key proteins: Bcl-2, Bax, and Caspase-3. We retrieved flavonoid structures from PubChem and protein data from the Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB). The drug-likeness of these compounds was assessed using Swiss ADME, adhering to Lipinski's rule of five, while their anti-NSCLC probability was predicted using PASS Online. Molecular docking and screening were performed with PyRx, and the results were visualized using Discovery Studio. Our findings identified epigallocatechin 3-O-gallate and ellagic acid as the most promising anti-NSCLC candidates. Ellagic acid demonstrated the strongest binding affinity to Caspase-3, suggesting a potent pro-apoptotic effect. Epigallocatechin 3-O-gallate, on the other hand, exhibited the lowest binding energy across multiple target proteins, particularly Bcl-2 and Bax, indicating its broad pro-apoptotic potential. These results collectively suggest that flavonoids from S. cumini may hold significant promise as a source of novel anti-NSCLC agents, warranting further in vitro and in vivo investigations.

Identification of Arthropod Diversity in The Cemara Beach Mangrove Ecosystem Yulianti, Yulianti; Sazali, Munawir
International Journal of Science, Technology and Applications Vol 3 No 1 (2025): Volume 3 Number 1 Tahun 2025
Publisher : Alpatih Harapan Semesta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70115/ijsta.v3i1.322

Mangrove ecosystems play an important role in maintaining the balance of the coastal environment and become a habitat for various types of fauna, including arthropods. This study aims to identify the types of arthropods and determine the level of diversity in the mangrove ecosystem of Cemara Beach, West Lombok Regency. The method used is an exploratory survey method with sampling techniques using Hand Collecting and Sweep Netting in several mangrove vegetation zones. The presence of these arthropods suggests that the mangrove ecosystem in Cemara Beach still supports the life of various small organisms, although some environmental changes, such as deforestation and increased garbage are beginning to affect the presence of some species. Therefore, the results of this study can be the initial basis for sustainable mangrove conservation and management efforts, while affirming the importance of the role of arthropods in maintaining the balance of coastal ecosystems.

Implementasi Pengelolaan Keuangan Negara Dalam Perspektif Ekonomi Islam (Studi APBN 2009-2017) Sazali, Munawir
Al-Intaj : Jurnal Ekonomi dan Perbankan Syariah Vol 6, No 2 (2020)
Publisher : Faculty of Economics and Islamic Business, UIN Fatmawati Sukarno Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29300/aij.v6i2.3639

The focus of this study is to determine the implementation of state financial management after the enactment of law number 17 of 2003 on the management of state finances in Indonesia (APBN) managed by the government in the period 2009-2017 as seen from the level of poverty, unemployment and external debt country to the impact of the management of the state budget over a period of 9 years which was examined through an Islamic economic perspective. The methodology used is a qualitative approach to Islamic economics and the analysis used is descriptive analysis. The data used are primary and secondary data. The results of this study indicate that the management of state finances in Indonesia after the enactment of Law No. 17 of 2003 there is a change in budget transparency and efficiency of budget use but there are undesirable impacts of poverty, unemployment and foreign debt that are still high, and the role of Islamic economics that must be optimized in the future is to help economic growth in Indonesia, in this case through the National Amil Zakat Agency and the Amil Zakat Institution.

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