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All Journal ILMU KELAUTAN: Indonesian Journal of Marine Sciences WMJ (Warmadewa Medical Journal) JURNAL PENDIDIKAN KEPERAWATAN INDONESIA Jurnal Ilmiah Kedokteran Wijaya Kusuma Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Syntax Literate: Jurnal Ilmiah Indonesia Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Oceana Biomedicina Journal Medical and Health Science Journal Medika Kartika : Jurnal Kedokteran dan Kesehatan Medicra (Journal of Medical Laboratory Science/Technology) Indonesian Journal of Medical Sciences and Public Health Oceana Biomedicina Journal Hang Tuah Medical Journal Surabaya Biomedical Journal Surabaya Biomedical Journal International Journal of Biomedical Science and Travel Medicine
Prawesty Diah Utami
Fakultas Kedokteran Universitas Hang Tuah
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Pengaruh Pemberian Ekstrak Rimpang Temulawak (Curcuma xanthorrhiza Roxb.) Terhadap Jumlah Eritrosit Mencit (Mus musculus L.) Jantan BALB/c yang Diinokulasi Plasmodium Berghei Anka AZARINE NEIRA AVISHA; PRAWESTY DIAH UTAMI
HANG TUAH MEDICAL JOURNAL Vol 15 No 2 (2018): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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ABSTRACT Malaria is still one of the most important infectious diseases in tropical countries because it can cause severe anemia and death. Nowadays, the choice for treatment of malaria is increasingly limited due to drug resistance. Hence, require the invention of new compounds to overcome them. The objective of this research was to perceive the effect of curcuma (Curcuma xanthorrhiza Roxb.) rhizome extract to the amount of erythrocytes in male BALB/c mice (Mus musculus L.) inoculated by Plasmodium berghei ANKA. This research was conducted experimentally with post-test only control group design using five groups of mice. One group was left normal while the other four groups were inoculated with Plasmodium berghei ANKA. From the groups inoculated with Plasmodium berghei ANKA, one group was given aquades and three other groups treated with curcuma (Curcuma xanthorrhiza Roxb.) extract with dose of 150 mg/KgBB, 100 mg/KgBB and 50 mg/KgBB for four days. On the fifth day, a blood test is performed to determine the amount of erythrocytes. The results of this study indicate that the amount of erythrocytesin male BALB/c mice (Mus musculus L.) inoculated byPlasmodium berghei ANKA and given rhizomesextract (Curcuma xanthorrhizaRoxb.) at doses of 150 mg/KgBB and 50 mg/KgBB wereinsignificantly decreased. Whereas the amount of erythrocytesin male BALB/c mice (Mus musculus L.) inoculated byPlasmodium berghei ANKA and given rhizomesextract (Curcuma xanthorrhiza Roxb.) at doses of 100 mg/KgBB weresignificantly decreased
Pengaruh Pemberian Ekstrak Temulawak (Curcuma Xanthorrizha Roxb.) Terhadap Level Nekrosis Pada Jaringan Lien Mencit Putih (Mus Musculus L.) Jantan Galur Balb/c yang Diinokulasi Plasmodium berghei ANKA Muhammad Reyhan Arsya; Prawesty Diah Utami; Irmawati Dikman
HANG TUAH MEDICAL JOURNAL Vol 16 No 2 (2019): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract Background : Malaria is a disease caused by the Plasmodium, transmitted by Anopheles mosquito and is a health problem in Indonesia. Further development to find new innovations in malaria treatment. Purpose : to determine the effect of temulawak rhizome extract on the level of spleen necrosis of male mice inoculated with Plasmodium berghei ANKA. Methods : a post-test only control group design, used five groups. First group a normal mice, 2nd group was inoculated with Plasmodium berghei ANKA and three treatment groups were inoculated with Plasmodium berghei ANKA and treated with temulawak extract with a dose of 150 mg/KgBB (3rd group), 100 mg/KgBB (4rd group ), and 50 mg/KgBB (5rd group) for four day. On the fifth day observation of the level of spleen necrosis was examination by histopathological Result : the administration of ginger rhizome extract has an influence on the level of necrosis of male mice (Mus musculus L.) BALB / c inoculated with Plasmodium berghei ANKA α = 0,002 (ρ<0,05), where the administration of temulawak extract can increase necrosis levels compared to the control group . This is probably due to the lack of temulawak extract dosage and lack of observation in this study. Conclusion : extract Curcuma xanthorriza Roxb. Has an influence on the level of necrosis of male mice inoculated with Plasmodium berghei ANKA Keywords : Malaria, curcuma (Curcuma xanthorrhiza Roxb.), Necrosis level, Plasmodium berghei ANKA
Hubungan Status Gizi Pasien Penyakit Hirschsprung dengan Infeksi Luka Operasi di RSPAL dr. Ramelan Surabaya Periode Waktu 2016-2020 PUTU SITHA AISHWARYA SARASWATI GIUR Giur; SAPTA PRIHARTONO RACHMAN; DIAH PURWANINGSARI; PRAWESTY DIAH UTAMI
HANG TUAH MEDICAL JOURNAL Vol 20 No 1 (2022): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v20i1.279

Abstract

Background: Hirschsprung's disease is a congenital intestinal motility disorder that causes functional intestinal obstruction due to the absence of enteric ganglion cells in the distal intestine. The management of each case of Hirschsprung's disease is surgery, where surgery on the digestive tract increases the occurrence of surgical site infections. Disturbances in the gut cause decreased resistance to infection, delayed cognitive development, and problems with nutritional status. Methods: This study was a descriptive and analytical observational study, where the primary data were taken from the registration data of Hirschprung's disease patients at RSPAL dr. Ramelan Surabaya in 2016-2020. The nutritional status of the patient was determined by plotting the weight per age curve according to WHO for children aged 0-5 years. Results: Observations of 38 patients who met the study requirements, obtained 4 patients who had poor nutritional status and 1 patient who had excess nutritional status, none of which experienced complications in the form of surgical wound infections. In 10 patients with poor nutritional status, 2 experienced complications in the form of surgical wound infection and 23 patients with good nutritional status, 1 experienced complications in the form of surgical wound infection. The results of the contingency coefficient correlation test showed P-value = 0.408 (p>α). Conclusion: There was no relationship between the nutritional status of Hirschprung's disease patients with surgical wound infections at RSPAL dr. Ramelan Surabaya Keywords: Hirschsprung's disease, nutritional status of children, surgical site infection.
Efek Pemberian Oksigen Hiperbarik Pada Efektivitas Ekstrak Cacing Tanah (Lumbricus terrestris) Terhadap Pertumbuhan Salmonella Typhi Secara In Vitro VARIDIANTO YUDO TJAHJONO; RETNO BUDIARTI; PRAWESTY DIAH UTAMI
HANG TUAH MEDICAL JOURNAL Vol 20 No 1 (2022): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v20i1.341

Abstract

Background: Typhoid fever is an infectious disease of the small intestine caused by the bacterium Salmonella typhi, and causes a fairly high mortality rate. These bacteria have developed resistance to many antibiotics. Earthworm extract (ECT) has been widely used as an alternative to treat typhoid fever. Hyperbaric oxygen therapy (OHB) has been used to treat various diseases and can suppress the growth of bacteria. Objective: To determine the effect of hyperbaric oxygen (OHB) 3 ATA on the effectiveness of earthworm (Lumbricus terrestris) extract on the growth of Salmonella typhi in vitro. Methods: This experimental study used the post-test only control group design method. Thirty-six samples of S.typhi bacteria in liquid medium (broth) were divided into four groups. The first group (K-) was not given any treatment, the second group (P1) was given earthworm extract, the third group (P2) was given hyperbaric oxygen 3 ATA, and the fourth group (P3) was given a combination of earthworm extract and hyperbaric oxygen 3 ATA. The results of bacterial growth in each group were calculated in colony forming units (CFU) / ml and analyzed statistically. Results: The growth of S.typhi bacteria in the first group (K-) was 108.51 x 106 CFU/ml, the second group (P1) was 483 CFU/ml, the third group was 1.4 x 106 CFU/ml, and the fourth group (P3) was 215 CFU/ml. The fourth group (P3) had the smallest number of bacterial growth and had a significant difference compared to the first (P1) and third (P3) groups (p = 0.001; p < α ; α = 0.05), but the difference was not significant compared to the second group (P1 ) (p = 0.308; p > α; α = 0.05). Conclusion: Giving earthworm extract (ECT) with hyperbaric oxygen (OHB) 3 ATA (combination) was most effective in inhibiting the growth of Salmonella typhi bacteria compared to giving earthworm extract (ECT) alone or giving hyperbaric oxygen (OHB) 3 ATA alone.
Profil Pasien Kanker Payudara Yang Menjalani Kemoterapi Di Rspal Dr. Ramelan Surabaya Periode Januari – Desember 2021 SEKAR KURNIA CAHYA; ANANG MUFTI SUMARSONO; PRAWESTY DIAH UTAMI
Hang Tuah Medical Journal Vol 22 No 1 (2024): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v22i1.416

Abstract

Background : Breast cancer is the most frequent cancer that occurs in Indonesia and becomes the main cause of mortality. Progression of breast cancer is affected by various factors, such as age, occupational status, menopause, estrogens, and lifestyle with high-fat dietary and alcohol consumption. Breast cancer progressivity may be stopped by surgery, chemotherapy, radiation, and hormonal therapy. Chemotherapy is an anticancer treatment management with the aim of killing cancer cells in the body and preventing recurrence and metastasis by administering cytotoxic agents. Chemotherapy may be performed previous to surgery (neoadjuvant) to achieve the decreased size of the tumor and facilitate the resection surgery. It may be performed as well after the surgery (adjuvant) to destroy any residual tumor cells. This study aimed to describe the profile of breast cancer patients who underwent chemotherapy from January to December 2021 at RSPAL Dr. Ramelan Surabaya. Methods: This study was descriptive with a retrospective design. Data collected from secondary sources of medical records patients with breast cancer in RSPAL Dr. Ramelan Surabaya from January to December 2021. Results: From the 79 samples, the most frequent age group in this study was a group of pre-elderly (45-59 years old). Most breast cancer patients are housewife. Breast cancer was commonly found in stage III. The most frequent chemotherapy management implemented for the breast cancer patient was adjuvant chemotherapy. Conclusion: women aged 45-59 years, not working, stage III, receiving adjuvant chemotherapy. Keywords : breast cancer, age, occupation, staging, chemotherapy
Co-Authors Anang Mufti ANANG MUFTI SUMARSONO Annisa U. Rasyida AZARINE NEIRA AVISHA Diah Purwaningsari Djatiwidodo Edi Pratiknya Erina Yatmasari Felly Moelyadi Grissabel Bethrin Jiantoro I Made Prasetya Kurniawan Indi Jazilah Irma Andriani Pasaribu Irmawati Dikman Irmawati M. Dikman Ismy Azizah Sisnawati Jessica Euodia Adidharma Kusbijantoro, Yemima Billyana Luh Putu Diah Ayuning Mita Herdiyanti Mufti, Anang Muhammad Reyhan Arsya Pramita A. Nugraheni Purwoko, Agus Putri, Jeanaya Hedya Alfara PUTU SITHA AISHWARYA SARASWATI GIUR Giur R. Varidianto Yudo Tjahjono Rayhan Ali Fadli Retno Budiarti Retno Budiarti RISMA Rizka Indah Ramadina Ronald P. Adiwinoto SAPTA PRIHARTONO RACHMAN Satria Bintang Samudra SEKAR KURNIA CAHYA Setianingsih, Herin Sukmana, Judya Tjahjono, R. Varidianto Yudo Wahyu P. Mutiadesi Wibowo, Prajogo Widjaja, Jordan Steven Wulandari, Ni Made Diah Zahratul Noreisza Rakhmadi Zuhro Putri Febrianti Febrianti