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Tinjauan terhadap Alternatif Sistem Pengolahan Senyawa Aktif Farmasi pada Limbah Cair Medis Fauzan Razansyah; Mindriany Syafila
Jurnal Teknik Lingkungan Vol. 28 No. 2 (2022): Jurnal Teknik Lingkungan
Publisher : ITB Journal Publisher, LPPM ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.tl.2022.28.2.4

Abstract

Hospital wastewater contains various substances that are used for medical, laboratory, research purposes, feces from patients, and also including pharmaceutically active compounds (PhACs). Environmental problems can arise due to the presence of PhAC in water bodies. The active pharmaceutical compounds themselves were originally designed to affect humans and animals physiologically even at low concentrations. These compounds remain in the environment for a long time and are not degraded biologically or naturally. Therefore, to design an WWTP system in hospitals that is able to treat medical liquid waste, research on PhACs is very much needed. This study aims to identify the pollutants contained in hospital wastewater effluent and to review the WWTP system that is able to process hospital wastewater effluent efficiently. Data on non-domestic liquid waste treatment processes were obtained based on research conducted by researchers, so this research was conducted based on literature studies. Indonesia does not yet have regulations governing PhACs in liquid waste, so hospitals in Indonesia have not been able to treat liquid waste that is free of PhACs. Variants of PhACs found in hospital wastewater are very diverse, and this makes it quite difficult to determine an efficient method to degrade PhACs levels in water. However, ozone-based AOPs have been widely used in the field of air remediation because of their low maintenance time, low cost, and high degradation efficiency.
Mekanisme Biosorpsi Senyawa Polutan Organik Persisten (POPs) dalam Pengolahan Limbah Cair Industri Farmasi: Suatu Review Nisa Nurhidayanti; Mindriany Syafila; Agus Jatnika Effendi; Dyah Wulandari Putri
Jurnal Ilmu Lingkungan Vol 21, No 2 (2023): April 2023
Publisher : School of Postgraduate Studies, Diponegoro Univer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jil.21.2.408-419

Abstract

Industri farmasi menghasilkan senyawa aktif farmasi yang bersifat persisten dan berbahaya bagi lingkungan dan makhluk hidup jika memasuki badan air. Pengolahan air limbah secara konvensional belum mampu menyisihkan senyawa aktif farmasi dengan baik. Review artikel ini dilakukan karena semakin meningkatnya populasi penduduk di Indonesia maka semakin meningkat pula produksi dan penggunaan produk obat-obatan dari industri farmasi. Pelepasan kandungan mikropolutan obat-obatan yang bersifat persisten ke dalam saluran pembuangan air adalah sekitar ng ~ µg/L secara terus menerus mengalir ke lingkungan dan air limbah akan membahayakan kesehatan makhluk hidup dan lingkungan. Senyawa aktif farmasi yang bersifat persisten terdiri dari analgesik dan antiinflamasi, antibiotik, antidiabetik, antihipertensi, beta-blocker, diuretik, lipid regulator, obat psikiatri, reseptor antagonis, hormon, beta-agonis, antineoplastik, produk topikal, antiseptik, agen kontras dan agen anti kanker. Artikel ini mereview mekanisme biosorpsi beberapa biosorben yang digunakan dalam menurunkan senyawa POPs dalam pengolahan limbah cair industri farmasi yang terdiri dari biomassa dari limbah pertanian dan limbah industri. Mekanisme biosorpsi senyawa POPs dalam pengolahan limbah cair industri farmasi meliputi interaksi elektrostatik, interaksi ikatan π-π elektron donor akseptor, ikatan hidrogen, pengisian pori, interaksi hidrofobik, atraksi dipol permanen, pertukaran ion, interaksi asam basa Lewis, gaya Van der Waals, dan fotodegradasi. Arah pengembangan penelitian berikutnya yaitu pengembangan biosorben dari limbah yang dimodifikasi kimia untuk mengoptimalkan kapasitas biosorpsi senyawa POPs dalam pengolahan limbah cair industri farmasi.
Effect of Activated Carbon Particle Size on Methylene Blue Adsorption Process in Textile Wastewater Akhmad Masykur Hadi Musthofa; Mindriany Syafila; Qomarudin Helmy
Indonesian Journal of Chemistry Vol 23, No 2 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.79784

Abstract

Up to 60–70% of the total textile dyes produced are azo dyes. An example of azo dye is methylene blue, which is commonly used in dyeing wool, silk, and cotton. This substance possessed harmful effects on the environment. Therefore, the removal process is mandatory. The adsorption process is a common method for dye removal in wastewater. One innovation to increase adsorption efficiency even further is by reducing adsorbent particle size. To understand the effect of adsorbent particle size on the adsorption process, in this study, granular activated carbon (GAC) was pulverized into powder (PAC) and superfine powder (SPAC). Adsorbent characterizations, isotherm, kinetics, and thermodynamics tests were conducted. Based on this study, surface area, pore volume, and adsorption capacity were increased for smaller adsorbent particle sizes. Isotherm and kinetic analysis showed that there was no difference in the isotherm and kinetic models that applied to each activated carbon, but there was an increase in the isotherm and kinetic coefficient values at smaller particle sizes. Meanwhile, based on the thermodynamic test, there were differences in the dominant adsorption mechanism for each activated carbon. In GAC and SPAC, the dominant adsorption mechanism was electrostatic interactions, while in PAC was van der Waals forces.
THE CHARACTERISATION AND POLLUTANT LOAD OF GREYWATER CONTAINING PERSONAL CARE COSMETIC PRODUCTS (PCCPS) FOR BODY CARE Marisa Handajani; Indira Nathania Pamio; Mindriany Syafila; Nur Novilina Arifianingsih
INDONESIAN JOURNAL OF URBAN AND ENVIRONMENTAL TECHNOLOGY VOLUME 6, NUMBER 2, OCTOBER 2023
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/urbanenvirotech.v6i2.16833

Abstract

Personal Care Cosmetic Products (PCCPs) are used on the exterior of the body, such as the skin, nails, hair, lips, external genitalia, teeth, and oral membranes. Greywater from a bathing activity is a significant contributor to domestic wastewater quantity. The greywater contains residual substances from the rinsing process of body care products. Aim: This study will focus on the characteristic and the specific pollutant load of greywater generated from the usage of shower gel. Methodology and Results: The characterization and specific pollutant loads are conducted based on artificial greywater which is made from three brands of shower gel which is diluted in tap water. The greywater from body cleaning activities has a pH value in the range of 7.26-7.33; total phosphate in the range of 1.71-3.09 mg/L; the value of NTK total Kjedahl nitrogen in the range of 2.45-4.03 mg/L; total COD in the range of 380.97-506.16 mg/L; dissolved COD values in the range of 310.92-393.68 mg/L; TSS value in the range of 62-229.50 mg/L; and TDS values in the range of 283-376.67 mg/L. The specific pollutant load generated from shower gel usage in greywater are 0.012 g TP/person/day; 0.016 g TKN/person/day; 2.14 g Total COD/person/day; 1.59 g dissolved COD/person/day; 0.94 g/person/day for TSS; and 1.48 g/person/day for TDS. Conclusion, significance, and impact study: The Greywater from shower gel usage contains physical and chemical constituents that can promote environmental deterioration. The finding of this research will provide useful information for domestic wastewater management and system design, especially for urban areas in Indonesia.
DEKOLORISASI ZAT WARNA AZO MENGGUNAKAN ADVANCED OXIDATION PROCESS BERBASIS OZON Qomarudin Helmy; Mindriany Syafila
Arena Tekstil Vol 38, No 1 (2023)
Publisher : Balai Besar Tekstil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31266/at.v38i1.8142

Abstract

Industri tekstil dalam proses manufakturnya, membutuhkan air dalam jumlah yang sangat banyak dimana kurang lebih 70% dari air proses tersebut akan berubah menjadi air limbah. Limbah cair industri tekstil diketahui mengandung senyawa warna yang sulit terdegradasi sehingga dapat menyebabkan permasalahan nilai estetika di badan air penerima, membahayakan keanekaragaman hayati dan mengandung bahan toksik dan karsinogenik yang mengganggu kesehatan manusia dan makhluk hidup lainnya. Kebanyakan industri tekstil di Kawasan Bandung membuang air limbahnya ke Sungai Citarum Hulu yang mengandung zat warna berupa zat warna azo. Salah satu teknologi pengolahan lanjutan untuk dekolorisasi warna adalah Advanced Oxidation Process (AOP) dengan ozon (O3) yang mampu dekolorisasi limbah efluen tekstil. Proses ozonasi dilakukan pada reaktor bervolume 16 L secara batch pada zat warna Reactive Black 5 (RB5), Reactive Yellow (RY), dan Reactive Blue (RB) dengan variasi konsentrasi 5 mg/L, 10 mg/L, 15 mg/L dan variasi dosis ozon 7,44 mg/menit dan 22,32 mg/menit. Dekolorisasi warna RB5, RY, dan RB di variasi konsentrasi 5 mg/L dan 10 mg/L mencapai 100% pada dosis ozon sebesar 22,32 mg/menit. Dekolorisasi warna pada variasi konsentrasi warna 15 mg/L dengan variasi dosis ozon 22,32 mg/menit untuk RB5 99,77% sedangkan RY dan RB mencapai 100%. Hasil konsentrasi ozon terlarut yang terukur rendah menunjukkan bahwa ozon telah bereaksi dan mengoksidasi senyawa-senyawa organik yang terkandung dalam limbah. Penyisihan COD terbesar didapatkan pada reaktor dengan variasi dosis ozon 22,32 mg/menit, yaitu mencapai 100%. Hasil percobaan dekolorisasi warna azo yang terbaik berturut-turut adalah RB>RY>RB5.
PENGARUH PENGENDALIAN pH TERHADAP PEMBENTUKAN ETANOL DAN PERGESERAN PRODUK ASIDOGENESA DARI FERMENTASI LIMBAH CAIR INDUSTRI MINYAK SAWIT (The Influence of pH Control on Ethanol and Switch of Acidogenic Products Formation from Palm Oil Mill Effluent) David Andrio; Mindriany Syafila; Marisa Handajani; Dessy Natalia
Jurnal Manusia dan Lingkungan Vol 22, No 1 (2015): Maret
Publisher : Pusat Studi Lingkungan Hidup Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jml.18719

Abstract

ABSTRAKLimbah cair industri minyak sawit memiliki potensi sebagai substrat pembentukan etanol. Pemanfaatan kultur campuran dalam pembentukan etanol memiliki keuntungan karena tidak memerlukan sterilisasi substrat, namun akan dihasilkan berbagai produk samping dan sebaliknya pada Saccharomyces cerevisiae. Penelitian ini bertujuan untuk mempelajari pengaruh pengaturan pH terhadap pembentukan etanol dan produk asidogenesa. Rancangan penelitian terdiri dari reaktor bakteri anaerob dan ragi dengan perlakuan pengendalian pH pada rentang 6-6,5 dan tanpa pengendalian pH dengan pH awal fermentasi 6-6,5. Hasil penelitian menunjukkan Degree Acidification (DA), Total Asam Volatil (TAV) dan etanol tertinggi berurutan sebesar 0,32; 808,03 mg/L dan 24,03 mg/L pada reaktor bakteri dengan pengendalian pH; 0,23; 522,43 mg/L dan 23,12 mg/L pada reaktor tanpa pengendalian pH; 0,25; 775,78 mg/L dan 34,11 mg/L pada reaktor ragi dengan pengendalian pH dan 0,32; 866,71 mg/L dan 29,17 mg/L pada reaktor ragi tanpa pengendalian pH. Pengendalian pH fermentasi meningkatkan pembentukan produk asetil-KoA dari 4,35% menjadi 7,34% pada reaktor bakteri dan dari 17,92% menjadi 18,78% pada reaktor ragi dan tidak berpengaruh terhadap pembentukan etanol. ABSTRACTPalm oil mill effluent has potention for substrate to ethanol formation. Utilization of anaerobic mixed culture bacteria to form ethanol has advantages i.e not requiring sterilization of the substrate and vice versa in Saccharomyces cerevisiae, but resulting side products. The aims of this research are to study effect of controlling pH on ethanol formation and acidogenic products. Design experiment consisted of anaerobic bacteria and yeast reactor with the pH control in the range of pH 6 - 6.5 and initial pH 6-6.5 for without pH control treatment. The results showed the highest Degree Acidification (DA), Total Volatile Fatty Acid (TVFA) and ethanol are 0.32; 808.03 mg/L and 24.03 mg/L for bacteria reactor with pH control; 0.23; 522.43 mg/L and 23.12 mg/L for bacteria reactor without pH control; 0.25; 775.78 mg/L and 34.11 mg/L for yeast reactor with pH control and 0.32; 866.71 mg/L and 29.17 mg/L for yeast reactor without pH control. Controlling pH increasing acetyl-CoA product formation from 4.35% to 7.34% for bacteria reactor and from 17.92% to 18.78% for yeast one and not affect to rising ethanol formation.
STATISTICAL ANALYSIS IN SELECTING THE BEST ELECTRODE BETWEEN ALUMINUM AND IRON IN TSS REMOVAL USING ELECTROCOAGULATION Mindriany Syafila; Muhammad Sonny Abfertiawan; Marisa Handajani; Faiz Hasan; Hanifah Oktaviani; Nur Novilina Arifianingsih
INDONESIAN JOURNAL OF URBAN AND ENVIRONMENTAL TECHNOLOGY VOLUME 6, NUMBER 2, OCTOBER 2023
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/urbanenvirotech.v6i2.17835

Abstract

Indonesia is a country that has considerable coal reserves with coal resources of 149.01 billion tons. One of the problems of coal mining is turbidity. The turbidity is caused by the excavation of the open pit mine so that rainwater contact with the main wall. So that mud is formed, which can increase turbidity levels. The concentration of Total Suspended Solids (TSS) due to this phenomenon reaches 5,400 mg/L. Aim: This study aims to set aside TSS by electrocoagulation processing method using a batch system with eight pairs of iron electrodes arranged monopolarly. Methodology and Results: Comparisons using statistically independent t-tests showed that there was no significant difference between the iron and aluminium electrodes in the pH parameter. Conclusion, significance, and impact study:There were significant differences between iron and aluminum electrodes in the parameters of TDS and TSS. In the measured TDS and TSS parameters, the electrocoagulation process using iron electrodes has a higher value than aluminum electrodes. In the TSS removal, there is no significant difference between the two electrodes (iron and aluminium).
Adsorption of Crystal Violet with Magnetic Graphene Oxide Nano Adsorbent Synthesized from Schima wallichii Wood Danar Arifka Rahman; Mindriany Syafila; Qomarudin Helmy
Indonesian Journal of Chemistry Vol 24, No 1 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.80894

Abstract

The textile industry continues to experience production developments to reach a target for the country's economic development. The increase in production leads to an increase in the amount of waste generated. Dyes such as crystal violet (CV) in textile wastewater are toxic and difficult to remove by conventional treatment. Adsorption with nano adsorbent has been widely researched and developed to remove dyes in the environment because it has various advantages. Magnetic graphene oxide (GO-Fe3O4) as a006E adsorbent has been widely studied because it has a large surface area, strong chemical bonds and is easily separated from the aqueous phase. Puspa (Schima wallichii) wood has the potential to be used as a natural source of graphite. The characterization of the adsorbent was tested with FTIR, SEM-EDS, and BET. The equilibrium time for the adsorption process was 20 min, while the optimum adsorbent dose was 0.04 g. Adsorption isotherm and kinetics analysis showed that CV adsorption using MGO followed Langmuir and pseudo-second-order models, respectively. Thermodynamic studies displayed that the CV adsorption was endothermic and spontaneous. The results of this study suggested that the adsorption of CV using GO-Fe3O4 nano adsorbent from S. wallichii wood proceeds by chemisorption and physisorption.
Characterization of Antibiotic Trimethoprim Adsorption by Granular Activated Carbon Fauzan Razansyah; Mindriany Syafila; Marisa Handajani
Jurnal Serambi Engineering Vol. 9 No. 3 (2024): Juli 2024
Publisher : Faculty of Engineering, Universitas Serambi Mekkah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The presence of antibiotics in aquatic environments has been known to lead to the development of bacteria with resistant genes. One type of antibiotic that has been found in the environment is trimethoprim, necessitating methods to remove this substance from the environment. Adsorption is a process that has been extensively studied in the field of water remediation. This study aims to investigate the adsorption of trimethoprim by granular activated carbon (GAC). Experiments were conducted by creating artificial wastewater containing distilled water and trimethoprim, which was then contacted with the adsorbent with variations in pH and trimethoprim concentration measured periodically up to the 3rd hour. Trimethoprim detection was performed using a UV-Vis spectrophotometer. The contact time required to reach equilibrium increased with the initial concentration of trimethoprim. The variations in initial trimethoprim concentrations of 5, 10, 20, 35, and 50 mg/L reached adsorption equilibrium after a contact time of 180 minutes with a GAC mass of 3 grams. All the percentages of trimethoprim removal after the contact time of 180 minutes at various concentrations used in this study were above 98%. The pH level has been proven to affect the trimethoprim removal process. The pseudo-second-order kinetic model has a high correlation with the adsorption process of trimethoprim by GAC. The isotherm model suitable for the interaction between trimethoprim and GAC was the Freundlich model.
Indeks Sanitasi dan Faktor-Faktor Penentunya Pada Area Urban Poverty Kota Bandung(Studi Kasus: Kecamatan Bandung Wetan, Kota Bandung) Jasmine Raissa Rachmadina; Mindriany Syafila; Dyah Wulandari Putri
Jurnal Serambi Engineering Vol. 9 No. 4 (2024): Oktober 2024
Publisher : Faculty of Engineering, Universitas Serambi Mekkah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Universal access to water, sanitation and hygiene (WASH) is a basic human right that reflects well-being. However, disparities in access to WASH persist in Indonesia, influenced by economic factors, education and sanitation behaviours. In urban areas, urban poverty exacerbates the gap in access to WASH, with the urban poor vulnerable to inadequate sanitation due to economic and knowledge constraints. In Kecamatan Bandung Wetan, which is located in the middle of Bandung city, this condition is still found, where low-income groups are vulnerable to the fulfilment of proper sanitation. The sanitation index is a tool to evaluate the sanitation system in a community. The sanitation index was analysed using exploratory factor analysis. The variables that make up the index are based on the 5 pillars of Community-Led Total Sanitation (CLTS). The results of the analysis show that the sanitation index in Kecamatan Bandung Wetan is built by the factors of clean water use, household welfare, low prevalence of environmental diseases, faecal user interface, and final disposal of household waste, with the highest sanitation index value found in Kelurahan Citarum.