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All Journal Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Indonesian Journal of Pharmaceutical Science and Technology JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun JFIOnline Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks
Yohannes Alen
Fakultas Farmasi Universitas Andalas, Padang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Isolation of Secondary Metabolite A. niger “In-Habiting” Queen M. gilvus Hagen.’s Nest Yohannes Alen; Atika Melati; Gemmy Sarina; Akmal Djamaan
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 2 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (524.816 KB) | DOI: 10.24198/ijpst.v5i2.15364

Abstract

Aspergillus niger is pathogen fungi that can live in various locations and can live contiguous with many hosts, one of them is queen termite’s nest. The aims of the study were to isolated the secondary metabilite of A.niger. Extraction proccess of secondary metabolite compounds was carried out by maceration method using methanol solvent. Based on that proccess, methanol extract was be yield 4,32% sample weight. Fractination proccess was carried out in the separating funnel using ethyl acetate solvent, which ethyl acetate fraction was be yield 14.39% methanol extract. Separation of the compounds was carried out by column chromatography method using n-hexane and ethyl asetate eluents. Purification of the compounds were done by recrystallization method using n-hexane and ethyl asetate. Two secondary metabolite compounds were successfully isolated from ethyl acetate fraction of the methanolic extract of fungus A. niger “In-Habiting” queen termite’s nest M. gilvus Hagen. Based on organoleptic examination, the compound signed AM-12-22-01 is 35 mg, white needle crystals, melting point 151-153 oC. While, the AM-12-60-01* is 15 mg, white needle crystals, melting point 91-93 oC. Based on the chemical analysis, thin layer chromatography, ultraviolet and infrared spectra data it was identified that AM-12-22-01 and AM-12-60-01 were a phenolic compounds.Key words: isolation, A. niger, In-Habiting, M. gilvus Hagen.
Analisis Kromatografi Lapis Tipis (KLT) dan Aktivitas Antihiperurisemia Ekstrak Rebung Schizostachyum brachycladum Kurz (Kurz) pada Mencit Putih Jantan Yohannes Alen; Fitria Lavita Agresa; Yori Yuliandra
Jurnal Sains Farmasi & Klinis Vol 3, No 2 (2017): J Sains Farm Klin 3(2), Mei 2017
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (484.954 KB) | DOI: 10.29208/jsfk.2017.3.2.141

Abstract

Thin-layer chromatography (TLC) analysis of bamboo shoot extract (Schizostachyum brachycladum) and its antihyperuricemic activity evaluation on male mice have been conducted. The extraction was processed by the maceration method, while the determination of the compound was carried out by using various color reagents of TLC plate. To evaluate the antihyperuricemic activity of the extract, a total of 25 male mice were hyperuricemic-induced with daily chicken liver homogenates along with extract suspension at doses of 25, 50 and 100 mg/kg, allopurinol 10 mg/kg, and control group. Another group consisted of 5 mice was treated as the normal group. Serum uric acid level of mice was measured by using the spectrophotometer at the 8th day and analyzed with one-way ANOVA. The TLC analysis showed that the extract contained phenolic compounds and triterpenoids. The measurement of serum uric acid levels revealed that the extract at doses of 25, 50 and 100 mg/kg significantly decreased the uric acid levels of male white mice as compared with control (p<0.05). However, all doses did not show any significant difference in reducing the uric acid level (p>0.05). The study concluded that bamboo shoot extract exhibited antihyperuricemic activity. The effect was seen even at the lowest dose evaluated. 
Pemeriksaan Residu Pestisida Profenofos pada Selada (Lactuca sativa L.) dengan Metode Kromatografi Gas Yohannes Alen; Zulhidayati Zulhidayati; Netty Suharti
Jurnal Sains Farmasi & Klinis Vol 1, No 2 (2015): J Sains Farm Klin 1(2), Mei 2015
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (436.746 KB) | DOI: 10.29208/jsfk.2015.1.2.30

Abstract

The determination of profenofos pesticidal residue in the lettuce (Lactuca sativa L.) by using gas chromatography using flame photometric detector (FPD) had been investigated. The lettuce was collected from Padang Luar area, Agam distric, West Sumatera. Sample for determination of profenofos residue divided into three groups: unwashed (A), washed with water (B), and washed with detergent (C). Maceration with sonication was used for the extraction using ethylacetateas a solvent. The results showed that profenofos pesticide residue in sample A, B and C were 0.204, 0.080 and 0.061 ppm, respectively. These profenofos pesticidal residue are over than the Maximum Residue Limits (MRL) that established by The Japan Food Chemical Research Foundation (0.05 ppm) even though World Health Organization (WHO) has not established Maximum Residue Limits (MRL) profenofos on lettuce. Based on the statistical analysis one-way method (Anova) using SPSS 20.0 showed that there was a significant concentrations difference between lettuce A from lettuce B and lettuce C with p < 0.05.
Penyuluhan dan Pelatihan Penggunaan Obat Tradisional serta Penerapan Hasil Penelitian Tumbuhan Sungkai (Peronema canescens Jack) kepada Masyarakat Dwisari Dillasamola; Yufri Aldi; Fatma Sri Wahyuni; Hansen Nasif; Yohannes Alen
Warta Pengabdian Andalas Vol 30 No 1 (2023)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.30.1.60-66.2023

Abstract

Indonesians, particularly those residing in rural areas with abundant plant diversity, have long relied on traditional medicine that utilizes plants. Sungkai (Peronema canescens Jack.) is one example of a widely-used traditional medicine known for its immunity-boosting properties. However, many people need more awareness of the potential benefits and risks of plants like Sungkai, so it is necessary to provide education and training to promote proper usage and ensure public safety. This community service activity aimed to equip individuals with the knowledge and skills to process plants accurately, utilize them appropriately based on the severity of the illness, and avoid any adverse side effects or toxicity. The counselling method used in this initiative involves lectures, which is effective for individuals with varying education levels, especially the general public. This program has yielded promising results, with the community displaying strong enthusiasm for the initiative. Ultimately, education and counselling services can significantly improve public understanding and use of traditional medicine.
EDUKASI PENGGUNAAN OBAT ANTIBIOTIK YANG BAIK DAN BENAR TERHADAP MASYARAKAT DI NAGARI SIPINANG PALEMBAYAN KABUPATEN AGAM Noverial Noverial; Yohannes Alen; Dwisari Dillasamola
BULETIN ILMIAH NAGARI MEMBANGUN Vol 6 No 4 (2023)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i4.556

Abstract

Antibiotic resistance is a problem that arises in the community due to the high use of antibiotics inappropriately. The problem arises because of the lack of understanding of the community regarding the handling and use of antibiotic drugs. Microorganisms that have been resistant to antibiotics when given the same antibiotic, it cannot kill the microorganisms that are the target of this can cause antibiotic resistance. Therefore, the purpose of this activity is to provide knowledge and understanding to the community regarding the wise and good use of antibiotics to prevent drug resistance. This community education activity was carried out in nagari Sipinang, Palembayan District, Agam Regency, West Sumatra, with lecture education methods and open discussions with the community. Based on the results obtained, the community was very enthusiastic about this education and counseling activity and opened public knowledge related to antibiotic resistance. This community education activity was carried out in nagari Sipinang, Palembayan District, Agam Regency, West Sumatra, with lecture education methods and open discussions with the community. Based on the results obtained, the community was very enthusiastic about this education and counseling activity and opened public knowledge related to antibiotic resistance. This activity is expected to be a means for the community to use antibiotics wisely and well in the use of appropriate, accurate, and effective. In addition, this activity is also expected to provide the community with sufficient information to be wiser in obtaining and using antibiotics so that people are not afraid of antibiotic resistance if their use has been carried out properly and wisely. This activity is important because of the lack of information obtained by the community in Nagari Sipinang regarding the use of antibiotics so that this educational activity will also make people more concerned with health.
INOVASI MINUMAN SEHAT: DEMONSTRASI PEMBUATAN SIRUP SUNGKAI DI NAGARI SIPINANG, KECAMATAN PALEMBAYAN KABUPATEN AGAM Dillasamola, Dwisari; Nasif, Hansen; Alen, Yohannes; Aldi, Yufri; Syofyan, Syofyan; Sayyida, Alya
Jurnal Hilirisasi IPTEKS Vol 7 No 4 (2024)
Publisher : LPPM (Lembaga Penelitian dan Pengabdian kepada Masyarakat) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jhi.v7i4.820

Abstract

The Sungkai plant (Peronema canescens Jack.) is known for its various health benefits, particularly as a natural immunostimulant. In West Sumatra, this plant is abundant and widely used in traditional medicine. This activity aimed to provide education and a demonstration to the community on how to process Sungkai leaves into a healthy syrup, thereby increasing the use of this plant as a daily health drink. The event was conducted through a live demonstration in Kanagarian Sipinang, Palembayan District, Agam Regency. The process of making Sungkai syrup involved several stages, starting from selecting the leaves, boiling them, and mixing them with other ingredients such as sugar and/or lemon juice to enhance the flavor. The results of this activity showed high enthusiasm among participants, with a total of 40 attendees. Before the demonstration, data from questionnaires revealed that 80% of respondents had heard about Sungkai syrup. During the demonstration, most participants expressed great interest in the syrup-making process, particularly in the aspect of processing Sungkai leaves into an extract that can be used as a base for syrup. This demonstration successfully enhanced participants' knowledge and skills in utilizing Sungkai leaves as a healthy drink. With further education and support, Sungkai syrup has great potential to be developed as a flagship product that supports both public health.
EDUKASI MANFAAT SUNGKAI SEBAGAI SALAH SATU TANAMAN OBAT UNTUK MENINGKATKAN DAYA TAHAN TUBUH DI NAGARI SIPINANG PALEMBAYAN KABUPATEN AGAM Dillasamola, Dwisari; Aldi, Yuffri; Nasif, Hansen; Alen, Yohannes; Syofyan, Syofyan; Sayyida, Alya
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 7 No. 3 (2024)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i3.605

Abstract

Sungkai (Peronema canescens Jack) is one of the herbal plants used by the community to increase endurance and as a traditional medicine for various diseases. This plant is abundant in West Sumatra and has great potential as an immunostimulant. This aims to educate the public about the benefits of Sungkai and promote a healthy lifestyle. This community service activity was carried out in Kenagarian Sipinang, Agam Regency, by involving PKK women and the local community. The methods used included counselling on the benefits of Sungkai leaves, filling out questionnaires before and after counselling, and interactive discussions. The results of the education programme showed an increased understanding of the benefits of Sungkai, especially as an immunostimulant. Data from the questionnaire showed that only 40% of the total respondents knew that Sungkai could be used to increase immunity. The majority of respondents, 25%, were more familiar with Sungkai without knowing its health potential. After the implementation of the education programme, there was a significant increase in the community's understanding of the benefits of Sungkai. From the questionnaire results collected, it was found that 100% of the respondents reported increased knowledge about the various benefits of Sungkai, which can increase endurance and the community began to be interested in using sungkai leaves as medicine. Education on local medicinal plants such as Sungkai has proven to be effective in improving the health of the community.
EDUKASI PEMANFAATAN TANAMAN SUNGKAI SEBAGAI TANAMAN OBAT KELUARGA DI NAGARI PADANG LAWEH KECAMATAN SUNGAI PUAR KABUPATEN AGAM Dillasamola, Dwisari; Nasif, Hansen; Alen, Yohannes; Almahdy, Almahdy; Oktomalioputri, Biomechy; Sari, Azzahra Ayu
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 7 No. 3 (2024)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i3.633

Abstract

Indonesia is known for its abundant natural resources. Indonesian people have traditionally used herbal plants to maintain and overcome health problems. Traditional medicine is one of the alternative methods used to cure certain diseases. One of the plants that is often used as traditional medicine in Indonesia is Sungkai (Peronema canescens Jack.). The purpose of this activity is to provide education to the community about family medicinal plants (TOGA) which play an important role in maintaining health. With the survey conducted, it is hoped that this activity can have a good impact on the community. This activity was carried out in Padang Laweh, Sungai Pua District, Agam Regency, West Sumatra. Community service in the form of location surveys, education in raising awareness of the benefits of local herbal plants as the development of family medicinal plants (TOGA). Activities were carried out in August-September which were attended by 60 local people. The results of the education programme showed an increase in community understanding about the use of family medicinal plants (TOGA). The results obtained from the questionnaire data filled in by the community show that only 55% of the total respondents know the use of family medicinal plants (TOGA) can be used to improve body health. After education, the questionnaire data increased to 70%. So that the implementation of this education is considered to be able to increase community knowledge about plants that can be used as a medicine. With the implementation of this service, it can be concluded that this survey and education activity has succeeded in increasing the knowledge and utilisation of Sungkai Plants as medicinal plants by the community in Kenagarian Padang Laweh, Sungai Puar District, Agam Regency.
EDUKASI DAN PROMOSI KESEHATAN: PENGGUNAAN OBAT HERBAL YANG AMAN DAN EFEKTIF BAGI MASYARAKAT KECAMATAN PADANG UTARA KOTA PADANG Dillasamola, Dwisari; Nasif, Hansen; Alen, Yohannes; Almahdy, Almahdy; Andini, Airiza Fitri; Al-Khansaa, Syawwal
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 7 No. 3 (2024)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i3.642

Abstract

Herbal medicine is an alternative treatment made from natural materials such as plants, animals, or minerals and is often used by the community in addition to modern medicine. The use of traditional medicine in Indonesia is still believed by some people to treat various diseases. Herbal medicine has become an important part of traditional medicine in various parts of the world. Despite its potential, public knowledge regarding the safe and effective use of herbal medicines is still relatively low. For this reason, health promotion and education activities were carried out in the community to increase public understanding and knowledge about the use and benefits of herbal medicines. This activity was attended by 27 participants, mainly from mothers around the implementation location. Prior to the education, a questionnaire survey was conducted, which showed that 51.80% of the respondents had basic knowledge about herbal medicines. The enthusiasm of the participants was very high during the presentation of the material, indicating a great interest in understanding herbal medicine more deeply. The results of this activity showed a significant increase in knowledge among participants regarding the use of herbal medicine, especially in choosing cough medicines safely and effectively. It is hoped that this activity will not only have a positive impact on improving public health, but also equip them with a better understanding of using herbal medicines wisely and appropriately. With the high interest of the community in participating in this activity, it is concluded that this activity has a very positive impact on the community and fosters knowledge and awareness of the community to live a healthy life.
Co-Authors A. Manaf Ali Akmal Djamaan Al-Khansaa, Syawwal Aldi, Yuffri Almahdy A Andini, Airiza Fitri Atika Melati Biomechy Oktomalioputri, Biomechy Dachriyanus Dwisari Dillasamola Evi Guslianti Fatma Sri Wahyuni Fitria Lavita Agresa Guslianti, Evi Hansen Nasif Honesty, Resta Honesty, Resta Isna Mulyani M. V. Sargent Mardha Akhsanita Melati, Atika Meri Susanti N. H. Ladjis Netty Suharti Noverial Noverial Novi Safitri Rezki Amelia Rezki Amelia Rustini Rustini Sari, Azzahra Ayu Sarina, Gemmy Sayyida, Alya Syofyan Syofyan Yori Yuliandra Yufri Aldi Zulhidayati Zulhidayati