Claim Missing Document
Check
Articles

Found 12 Documents
Search

Aktivitas Antidiabetes dari Fraksi Air Lingzhi (Ganoderma lucidum (Curtis) P. Karst)) pada Tikus Diabetes dengan Induksi Aloksan Ningsih, Dwi
JURNAL PHARMASCIENCE Vol 2, No 1 (2015): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

AbstrakPenelitian ini dirancang untuk mengetahui pengaruh fraksi air G. lucidum dalam menurunkan kadar glukosa darah dan ekspresi p53 pada jaringan pankreas tikus diabetes yang diinduksi aloksan. Tiga puluh enam tikus dibagi menjadi enam kelompok yaitu normal, diabetes, glibenklamid dan tiga dosis fraksi air pengobatan kelompok G. lucidum (225, 450, dan 675 mg / KgBB). Tikus diabetes diinduksi aloksan intraperitoneal pada dosis 150 mg / KgBB. Keadaan diabetes terjadi pada hari ke-3 setelah pemberian aloksan dan menunjukkan peningkatan kadar darah sampai 274,00 ± 15,11 mg / dL. Pemberian oral fraksi air G. lucidum dan glibenklamid selama 9 hari setelah kondisi diabetes secara signifikan mengurangi kadar glukosa darah (P <0,05). Pada hari ke-10 setelah pengobatan, tikus yang dimatikan dan jaringan pankreas diambil untuk pengujian Haematoxyllin eosin. Hasil penelitian menunjukkan bahwa fraksi air G. lucidum menghambat apoptosis sel β. Perubahan morfologi jaringan pankreas dalam keadaan diabetes secara signifikan menurun dan berubah menjadi keadaan normal setelah pemberian berulang fraksi air G. lucidum.  Kata kunci: fraksi air  G. lucidum, Aloksan monohidrat, Diabetes melitus  AbstractThe present study was designed to investigate the influence of water fraction of G. lucidum toward lowering blood glucose level and p53 expression in pancreatic tissues in alloxan-induced diabetic rat. Thirty six rats were divided into six groups i.e. normal, diabetic, glibenclamide and three dosage of treatment water fraction of G. lucidum groups (225, 450, and 675 mg/KgBW).  Diabetic rats were induced by alloxan monohidrate intra peritoneally at the dose of 150 mg/KgBW. Diabetic state occurred on the 3rd day after alloxan administration and it was showed increasing blood level until 274.00 ± 15.11 mg/dL. Orraly administrations of water fraction of G. Lucidum and glibenclamide for 9 days after diabetic condition  were significantly reduce of blood glucose level (P<0.05). At the day 10th after treatment, rats were sacrified and the pancreatic tissues were harvested for Haematoxyllin eosin. The results showed that water fraction of G. lucidum inhibit the β cell apoptotic. The morphological change of pancreas tissue in a diabetic state was significantly decreased and turned into normal state after repeated administration of water fraction of G. Lucidum.  Keywords   : Water fraction of G. Lucidum,  Alloxan Monohidrat, Diabetes Mellitus
Pembuatan bahan penyamak nano nabati dan aplikasinya dalam penyamakan kulit Herminiwati, Herminiwati; Waskito, Sri; Purwanti, Christiana Maria Herry; Prayitno, Prayitno; Ningsih, Dwi
Majalah Kulit, Karet, dan Plastik Vol 31, No 1 (2015): Majalah Kulit, Karet, dan Plastik
Publisher : Center for Leather, Rubber, and Plastic Ministry of Industry, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (604.224 KB) | DOI: 10.20543/mkkp.v31i1.180

Abstract

This study aimed to create nano vegetable tanning materials of acacia bark extract. The process started with size reduction of acacia bark (16.7 mm x 4.9 mm x 1.8 mm), followed by counter current extraction of acacia bark with water at 80ºC with 1:3 bark to water ratio in order to obtain extracts with density of 9-10ºBe. Drying was done with a spray dryer. Particle size of the resulting powders was measured with particle size analyzer. Planetary ball mill was used for 6 hours to obtain average particle size of 72.9 nm. A variety of vegetable tanning materials were applied in the vegetable tanning process with varied concentrations of 15, 20, and 25%. The use of 25% nano vegetable tanning material of acacia bark extract gave the best results compared to liquid extract of acacia bark and mimosa. The properties of the leather obtained were tensile strength of 27.04 kg/cm2, elongation at break of 50%, shrinkage temperature of 84oC, and degree of tannage of 79.65%.Keywords: vegetable tanning material, nano particle, acacia bark, extraction, planetary ball mill.ABSTRAKPenelitian ini bertujuan untuk membuat bahan penyamak nano nabati dari ekstrak kulit kayu akasia. Proses pembuatannya dilakukan melalui tahapan pengecilan ukuran kulit kayu akasia (16,7 mm x 4,9 mm x 1,8 mm), dilanjutkan dengan ekstraksi kulit kayu akasia secara counter current menggunakan air 1:3 dengan suhu air awal 80ºC sehingga diperoleh ekstrak dengan densitas 9-10ºBe. Pengeringan dilakukan dengan spray dryer. Serbuk hasil spray dryer diukur partikelnya dengan particel size analyzer, kemudian diteruskan dengan pengecilan ukuran menggunakan planetary ball mill selama 6 jam sehingga diperoleh partikel berukuran rata-rata 72,9 nm. Berbagai bahan penyamak nabati diaplikasikan dalam proses penyamakan nabati pada kadar 15, 20, dan 25%. Penggunaan ekstrak nano nabati kulit kayu akasia sebesar 25% memberikan hasil terbaik dibanding ekstrak cair kulit kayu akasia maupun mimosa impor. Kulit tersamak yang dihasilkan memiliki kuat tarik sebesar 27,04 kg/cm2, kemuluran sebesar 50%, suhu kerut sebesar 84oC, dan derajat penyamakan sebesar 79,65%.Kata kunci: bahan penyamak nabati, partikel nano, kulit kayu akasia, ekstraksi, planetary ball mill.
Pemanfaatan air olahan wetland di Sitimulyo dalam pembuatan kulit pikel domba Ningsih, Dwi; Martianto, Teguh; Harjanto, Syaiful
Majalah Kulit, Karet, dan Plastik Vol 28, No 2 (2012): Majalah Kulit, Karet, dan Plastik
Publisher : Center for Leather, Rubber, and Plastic Ministry of Industry, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (712.233 KB) | DOI: 10.20543/mkkp.v28i2.111

Abstract

ABSTRACTResearch has been done to study the effects of treated wetland water utilization in Sitimulyo on the making of pickled sheepskin. The treated wetland water on the making of pickled sheepskin was done by using three variable ratio of wetland water: water that is 100:0; 75:25; 50:50. Used as a comparison was control or without any additional water wetland. Skin that was used as much as 12 pieces of sheepskin divided into 4 groups and 3 pieces of leather for each treatment. Quality parameters observed include skin moisture content, salinity, pH, and organoleptic observation. From the results showed that the treated wetland water in Sitimulyo not meet the water requirements for tanning leather according to SNI 06-0649-1989 on water for vegetable leather tanning process. Pickle skin test results show that the chemical (moisture, salt and pH) and organoleptic not meet the requirements of SNI 06-3537-1994 on quality leather and test methods pickle sheep.ABSTRAKTelah dilakukan penelitian untuk mempelajari pengaruh penggunaan air olahan wetland yang ada di Sitimulyo dalam pembuatan kulit pikel domba. Air olahan wetland dalam pembuatan kulit Pikel dilakukan dengan 3 variabel perbandingan air wetland:air bersih yaitu 100:0; 75:25; 50:50. Sebagai pembanding digunakan kontrol atau tanpa tambahan air wetland. Kulit yangdigunakan sebanyak 12 lembar kulit domba dibagi dalam 4 kelompok dan 3 lembar kulit untuk masing-masing perlakuan. Parameter mutu kulit yang diamati meliputi kadar air, kadar garam, pH, serta pengamatan organoleptis. Dari hasil penelitian menunjukkan bahwa air olahan wetland yang ada di Sitimulyo belum memenuhi persyaratan air untuk penyamakan kulit sesuai SNI 06-0649-1989 mengenai air untuk proses penyamakan kulit samak nabati. Hasil uji kulit pikel menunjukkan bahwa secara kimia (kadar air, garam dan pH) dan organoleptis tidak memenuhi persyaratan SNI 06-3537-1994 mengenai mutu dan cara uji kulit pikel domba.
Milk Tofu Onde Quality Ningsih, Dwi
ANIMAL PRODUCTION Vol 4, No 1 (2002): January
Publisher : Universitas Jenderal Soedirman, Faculty of Animal Science, Purwokerto-Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.193 KB)

Abstract

The study on “The Quality of Milk Tofu Onde” observed from its crispiness,colour,taste and texture was conducted to socialise the product of milk. Onde is a kind of snack which is popular in Indonesia and it easy to produce with simple eguipment. As much as 562.5 gs fresh milk tofu, 562.5 gs wither milk tofu and 1500 gs of wheat flour for the purpose of study. Data on crispiness, colour, taste and texture of milk tofu ande expressed in score, were obtained through 20 panelists and was analized with Randomized Group Design followed by an orthogonal polynomial teast. The first factors were sort of tofu (T) e.i fresh milk tofu and wither milk tofu. The second factors were level of tofu (S) e.i 50 percent, 75 percent and 100 percent of wheat flour or their proportion (g) were (125:125); (187.5:62.5); (100:0). The study showed that milk tofu onde from wither milk more crispy significantly (P>0.01) than those from fresh milk.  The level of tofu gave a significant effect (P>0.01) on crispiness. This was shown by  a quadrater  regression of : Y1 = c9.0712  + 0.5093X c  0.0030X2 and Y2 = c3.3865 + 0.4949X c 0.0033X2 for fresh milk tofu and wither milk tofu respectively. Milk tofu onde from wither milk more brownnes significantly (P>0.01) than those fron fresh milk. The level of  tofu gave a significant effect (P>0.01) on colour. This was shown by a linier regression of Y1 = 8.4244 + 4.4625x and Y2 = 8.7734  + 10.0745X for fresh milk tofu and wither milk  tofu respectively. Milk tofu onde from wither milk more delicious significantly (P>0.01) than those from fresh milk. The level of tofu gave a significant effect (P>0.01) on taste. This was shown by a linier regressions of Y1 = 8.3383 + 0.0422 X and by a quadrater regression of Y2 = 3.5200 + 0.5156 X – 0.0033 X2 for fresh milk tofu and wither milk tofu respectively. Texture of milk tofu onde from fresh milk more dense significantly (P>0.01) than tose from wither milk. The level of tofu gave a significant effect (P>0.01) on texture. This was shown by a linier regressions of Y1= 5.4150 + 11.9630 X and Y2= 10.7880 + 1.5633 X for fresh milk tofu and wither milk tofu respectively. The study indicated that milk tofu onde from wither milk being more crispy, brownness, delicious and denseless texture than those from fresh milk. The best level of milk tofu was 75% on daugh. (Animal Production 4(1): 11-20 (2002)Key words : “Milk tofu onde”, crispiness
Analisis Kemampuan Pemecahan Masalah Matematis Ditinjau dari Self Confidence Siswa Kelas VII SMPN 1 Nan Sabaris Ningsih, Dwi; Fitri, Dewi Yuliana; Cesaria, Anna
JURNAL PEMBELAJARAN DAN MATEMATIKA SIGMA (JPMS) Vol 9, No 2 (2023)
Publisher : Fakultas Keguruan dan Ilmu pendidikan (FKIP) Universitas Labuhan Batu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpms.v9i2.4858

Abstract

Penelitian ini bertujuan untuk menganalisis kemampuan pemecahan masalah berdasarkan self confidence siswa dalam pembelajaran matematika. Penelitian ini dilatarbelakangi oleh salah satu kemampuan yang harus dimiliki oleh siswa yaitu kemampuan pemecahan masalah. Jenis penelitian yang dilakukan adalah penelitian deskriptif dengan pendekatan kuantitatif. Subjek dalam penelitian ini adalah seluruh siswa kelas VIII 1 SMPN 1 Nan Sabaris dengan jumlah 24 siswa. Instrumen penelitian yang digunakan berupa tes kemampuan pemecahan masalah, angkat self confidence dan wawancara. Dideskripsikan berdasarkan hasil tes kemampuan pemecahan masalah, angket self confidence dan wawancara. Kemampuan pemecahan masalah tinggi dengan self confidence tinggi 8,33%, kemampuan pemecahan masalah tinggi self confidence 20,8% dan kemmapuan pemecahan masalah tinggi self confidence rendah adalah 4,16%. Untuk kemampuan pemecahan masalah sedang dengan self confidence tinggi 4,16%, kemampuan pemecahan masalah sedang slef confidence sedang 20,8%,dan unruk kemampuan pemecahan masalah sedang self confidence rendah 0%. Kemampuan pemecahan masalah rendah dengan self confidence tinggi 8,33%, kemampuan pemecahan masalah rendah self confidence sedang 25%, dan untuk kemampuan pemecahan masalah rendah slef confidence rendah alahag 8,33%.
AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN INGGU (Ruta angustifolia [L.] Pers) PADA TIKUS PUTIH JANTAN DENGAN METODE INDUKSI KARAGENAN DAN RADIASI UV Kusniawati, Mega Ayu; Ningsih, Dwi; Herowati, Rina
JURNAL ETNOFARMASI Vol 1 No 01 (2023): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Inflamasi merupakan suatu respon tubuh terhadap cedera. Salah satu tanda inflamasi adalah edema. Penelitian ini bertujuan untuk mengetahui aktivitas antiinflamasi ekstrak etanol daun inggu dan mengetahui dosis ekstrak etanol daun inggu yang memiliki aktivitas antiinflamasi paling optimal dengan metode induksi karagenan dan radiasi UV. Daun inggu diekstraksi dengan metode maserasi dengan etanol 96%. Pengujian dilakukan pada 25 ekor tikus dibagi dalam 5 kelompok yaitu kontrol negatif (CMC Na), kontrol positif (Natrium Diklofenak 4,5 mg/kg BB), ekstrak etanol daun inggu dengan dosis 25 mg, 50 mg dan 100 mg/kg BB. Pada metode induksi karagenan pengukuran aktivitas antiinflamasi dilakukan dengan mengukur volume edema pada telapak kaki tikus yang diinduksi dengan lambda karagenan 0,8%. Pada metode radiasi UV pengukuran aktivitas antiinflamasi berdasarkan skor eritema akibat induksi radiasi UVB. Data yang diperoleh dilakukan analisa ANOVA dan LSD untuk mengetahui perbedaan antar kelompok perlakuan. Hasil penelitian menunjukkan ekstrak etanol daun inggu dosis 25 mg, 50 mg dan 100 mg/kg BB mempunyai aktivitas antiinflamasi dengan metode induksi karagenan sedangkan dosis 50 mg dan 100 mg/kg BB mempunyai aktivitas antiinflamasi dengan metode radiasi UV. Ekstrak etanol daun inggu dosis 100 mg/kg BB mempunyai aktivitas antiinflamasi paling optimal dan sebanding dengan kontrol positif pada kedua metode. Kandungan yang diduga berefek sebagai antiinflamasi yaitu flavonoid dan steroid
PERBANDINGAN TARIF JASA RAWAT INAP DENGAN UNIT COST DAN ACTIVITY BASED COSTING SYSTEM PADA RUMAH SAKIT (STUDI KASUS PADA RS AT-TUROTS AL-ISLAMY YOGYAKARTA): (STUDI KASUS PADA RS AT-TUROTS AL-ISLAMY YOGYAKARTA) Ningsih, Dwi; kadari, Kadari
PRIMA EKONOMIKA Vol. 10 No. 2 (2019): Prima Ekonomika
Publisher : STIE "YKP" YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.647 KB)

Abstract

ABSTRACT This study aims to determine hospitalization rates comparation based on hospital calculation using Activity Based Costing System in 2015. The method used is descriptive analysis method. Data collection method uses in this research is using interviews and documentation methods. Based on the results of the study shows that: (1) the method is applied in RSU At-Turots Al-Islamy to determine tariffs for hospitalization is a method of unit cost, with rates for the VIP section of Rp 255,000; class I at Rp 165,000; class II amounting to Rp 122,500; and for class III amounting to Rp 85,000. (2) the service rates of hospitalization by Activity Based Costing System for VIP Rp 281,801; class I to Rp 170,371; class II Rp 137,217; and class III Rp 98,680. (3) Activity Based Costing System compared with the unit cost method provides more expensive result. In the overhead costs on the unit cost of each product is charged at only one cost driver of hospitalization days. In the activity based costing system, overhead on each product is charged to some cost driver that Activity Based Costing System is able to allocated cost activity in each product appropriately based on the consumption of each activity. Keywords: Hospitalization Rates, Unit Cost, ABC System ABSTRAK Penelitian ini bertujuan untuk mengetahui perbandingan perhitungan tarif jasa rawat inap berdasarkan perhitungan rumah sakit menggunakan Activity Based Costing System tahun 2015. Metode penelitian yang digunakan adalah metode analisis deskriptif. Sedangkan metode pengumpulan data yang dilakukan dalam penelitian ini adalah dengan menggunakan metode wawancara dan metode dokumentasi. Berdasarkan hasil penelitian menunjukkan bahwa: (1) Metode yang diterapkan RSUAt-Turots Al-Islamy untuk menentukan tarif jasa rawat inap adalah metode unit cost, dengan tarif untuk kelas VIP sebesar Rp 255.000, kelas I sebesar Rp 165.000, kelas II sebesar Rp 122.500, dan untuk kelas III sebesar Rp 85.000. (2) Tarif jasa rawat inap dengan menggunakan metode Activity Based Costing System untuk VIP sebesar Rp 281.801, kelas I sebesar Rp 170,371, kelas II sebesar Rp 137,217, dan kelas III sebesar Rp 98,680. (3) Activity Based Costing System dibandingkan dengan metode unit cost memberikan hasil yang lebih mahal. Pada metode unit cost, biaya overhead pada masing-masing produk dibebankan pada beberapa cost driver, sehingga Activity Based Costing System mampu mengalokasikan biaya aktivitas ke setiap produk secara tepat berdasarkan konsumsi pada masing-masing aktivitas. Kata Kunci: Tarif Jasa, Unit Cost, Sistem ABC
Pendampingan Strategi Penyusunan Modul Ajar Pada Kurikulum Merdeka Bagi Guru SD Gugus X Parepare Mas'ud B.; Malik, Marwati Abd.; Hasanuddin, Andi ilham Akbar; Sya'ih, Fhilda Yulinda; Ningsih, Dwi; Fatirah H.B, Akhnes Intan Sari; Hasdianti; Innawati; Jumarni; Jumiana; Mirnawati
Jurnal Pengabdian Magister Pendidikan IPA Vol 7 No 3 (2024): Juli - September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v7i3.9020

Abstract

Abstract: This research aims to evaluate the strategy for preparing teaching modules in the Independent Curriculum for elementary school teachers in Gugus X Parepare. The background to this research focuses on the importance of teaching modules as the main instrument in effective and efficient learning, which can support teachers in implementing the Independent Curriculum better. Quality teaching modules not only function as a guide for teachers, but also play a role in developing 21st century skills in students, such as critical thinking and creativity. This research method uses a community service approach which includes four stages: observation and planning, implementation, mentoring, as well as evaluation and follow-up. At the observation stage, needs were identified and objectives formulated through in-depth interviews with teachers. The implementation phase involved direct training attended by 84 elementary school teachers in Gugus X Parepare, with a focus on preparing teaching modules and implementation strategies for the Independent Curriculum. At the mentoring stage, teachers are guided in preparing teaching modules that are relevant to student needs and the local context. The evaluation stage includes collecting input, analyzing results, and planning follow-up actions to improve the teaching module. The research results show that this activity was successful in increasing teachers' understanding and skills in designing teaching modules that are in accordance with the Independent Curriculum. In this way, it is hoped that the quality of learning at Gugus X Parepare can improve significantly. Keywords: Independent Curriculum, Teaching Modules, Training, Basic Education
pengaruh penggunaan big book terhadap kemampuan membaca permulaan siswa sekolah dasar Ningsih, Dwi; Hermawan, Adi Iwan; Selfiani, Selfiani
FRASA: Jurnal Keilmuan, Bahasa, Sastra, dan Pengajarannya Vol. 6 No. 1 (2025): FRASA: JURNAL KEILMUAN BAHASA, SASTRA, DAN PENGAJARANNYA
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/frasaunimuda.v6i1.124

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh dari media Big Book terhadap kemampuan membaca permulaan peserta didik kelas I SD Inpres 16 Kabupaten Sorong. Penelitian yang digunakan dalam penelitian ini yakni penelitian kuantitatif dengan menggunakan desain penelitian pre eksperimental Design. Populasi dalam penelitian adalah peserta didik dari kelas 1 yang berjumlah 38 peserta didik. Instrumen pengumpulan data yang digunakan dalam penelitian ini adalah observasi dan tes (Pre-Test dan Post-Test). Analisis data yang digunakan dalam penelitian ini adalah dengan melakukan beberapa uji yaitu: 1. Uji Validasi, 2. Uji Reabilitas, 3. Uji Normalitas, 4. Uji T-test. Untuk mengetahui hasil uji tersebut peneliti menghitung hasil peserta didik dengan menggunakan aplikasi IBM SPSS V 29.0 Statistic For Windows. Kesimpulan dari penelitian ini adalah terdapat pengaruh media Big Book terhadap kemampuan membaca permulaan peserta didik kelas I SD Inpres 16 Kabupaten Sorong.
Pengaruh Pemberian Sediaan Creambath Ekstrak Daun Kembang Sepatu (Hibiscus Rosa-Sinensis) pada Pertumbuhan Rambut Kelinci (New Zealand) Widyastuti, Lita; Ningsih, Dwi; Aisiyah, Siti
Jurnal Farmasi (Journal of Pharmacy) Vol. 8 No. 1 (2019): Jurnal Farmasi (Journal of Pharmacy), October 2019
Publisher : Jurnal Farmasi (Journal of Pharmacy)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hibiscus rosa-sinensis is contains flavonoids, saponins and polyphenols that play a role in accelerating the growth of hair.This research aims to know the influence of the variation of concentration of ethanol extracts of hibiscus leaves in preparation creambath against rabbit hair growth. Of ethanol extracts of hibiscus leaves are obtained with the method remaseration using ethanol 70%. Creambath preparation made in 4 formula with the concentration of the extract of hibiscus in 10%, 15%, 20% and a negative control. Applied to the backs of rabbits that had been shaved and then given the preparations-2 times a day for 15 days. To test the activity of rabbit hair growth by measuring the length of the hair and rabbit hair, weight and physical test performed which include odor, color, pH, spread power, power protection, the ability to say, type, viscosity and stability of creams, creambath. Physical quality test data, weight, and hair is analyzed with the Saphiro-Wilk, then using ANOVA and Post Hoc Tests. The results showed that preparations creambath hibiscus leaves ethanol extract with a concentration of 10%, 15%, and 20% have good physical stability. The higher the concentration of the extract in preparations creambath hair growth activity differences produce rabbits. The results views of the parameter weights and lengths of hair, but not yet as effective as comparison control formula that delivers results-effective against the growth of rabbit hair creambath is with a concentration of 20%.