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All Journal International Journal of Public Health Science (IJPHS) Jurnal Ilmiah Farmasi Jurnal Keperawatan Indonesia Mutiara Medika: Jurnal Kedokteran dan Kesehatan Biomedika Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Keperawatan Padjadjaran Jurnal Keperawatan Muhammadiyah Journal of Telenursing (JOTING) Jurnal Aisyah : Jurnal Ilmu Kesehatan Prosiding Seminar Nasional Program Pengabdian Masyarakat Jurnal Kedokteran Hewan
Ikhlas Muhammad Jenie
Bagian Fisiologi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Muhammadiyah Yogyakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Correlation of body mass index on waist circumference and blood pressure Yoni Astuti; Ikhlas Muhammad Jenie
International Journal of Public Health Science (IJPHS) Vol 9, No 4: December 2020
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v9i4.20443

Abstract

The increasing number of elderly on these recent days demands an improved quality of health for the elderly. Independence of the elderly is important in order to be happy and not to be a burden on their families. Health monitoring continuously is an effort to prevent disruption on the health conditions of the elderly. The health status of elderly people is important to know to follow up on prevention programs for the emergence of certain diseases in the elderly. This study aims to look for potential health problems for elderly people in Gamping, Sleman, DIY, Indonesia. The method of this research was cross sectional analysis using secondary data. Sample collection is consecutive subjects. Subjects were 158 people with a mean age of men (67.8 ± 7.1) years while women were 67.5 ± 7.3 years. The data was analyzed using the bivariate correlation test with CI 99%. The results of the analysis showed that the average body mass index with an average waist circumference was positively correlated (r= 0.66; p: 0.000), but did not correlate with systole pressure (r= -0.009; p= 0.97) diastole (r= 0.093; p= 0.477), age (-0.05; p= 0.71), and gender (r= -0.146; p= 0. 27). The potential health problems among the elderly is the risk of high BMI due to the larger waist circumference
High Glucose, but Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells Ikhlas Muhammad Jenie; Budi Mulyono; Soedjono Aswin; Sri Kadarsih Soejono
International Journal of Public Health Science (IJPHS) Vol 4, No 3: September 2015
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.289 KB) | DOI: 10.11591/ijphs.v4i3.4735

Abstract

Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases. Platelet hyperreactivity has been frequently found in patient with diabetes mellitus. To examine whether testosterone and high glucose modify platelet aggregation through endothelial cells, we did an in vitro study using endothelial cells culture from human umbilical vein (HUVEC). Treatments were performed in HUVEC sub culture as either normoglucose (5.6 mM) or high glucose (22.4 mM) medium, with or without testosterone (0, 1, 10, 100 nM), for 24 hours. HUVEC were trypsinized, resuspended, and then incubated with platelet rich plasma from healthy male donors with ratio 1:104 for 3 minutes. Platelet aggregation measured by turbidimetry methode. This study showed that testosterone did not significantly influence platelet aggregation through endothelial cells in normoglucose (p = 0.144) or high glucose (p = 0.916) medium. There was no main effect of testosterone (p = 0.73) as well as no interaction between testosterone and glucose (p = 0.69), but there was a main effect of glucose (p = 0.004), to platelet aggregation through endothelial cells. In conclusion, high glucose, but not testosterone, inhibits platelet aggregation mediated by endothelial cells.
Cytoprotective effect of tangeretin in hydrogen peroxyde-inducedoxydative stress on human umbilical vein endothelial cells (HUVECs) Riris Istighfari Jenie; Irfan Muris Setiawan; Ikhlas Muhammad Jenie; Haruma Anggraini Muflikhasari
Jurnal Ilmiah Farmasi Vol. 11 No. 1 (2015): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol11.iss1.art3

Abstract

Oxydative stress is known as a major trigger in cardiovascular dysfunction that leads to hypertension, atherosclerosis, and chronic heart failure. Polymethoxyflavone such as tangeretin and nobiletin has been reported to have biological activity including reducing cholesterol level and anti inflammation activity. The critical point that mediates atherosclerosis is the formation of stress oxidative which causes endothelial cells dysfunction.This study was conducted to explore the effect of tangeretin in protecting H2O2-induced oxidative stress on HUVEC. Cell viability was determined by using MTT assay. Cells were treated with different concentrations of tangeretin (12.5; 100; and 200 µM) for 24h before exposed to 600 µM H2O2 for 4h. Cells viability analyses showed that at low concentration (12.5 µM), tangeretin inhibited H2O2-induced cytotoxicity. Furthermore, it induced cells proliferation. However, at high concentration, it failed to protect HUVEC from H2O2-induced cytotoxicity and increased the cytotoxicity of H2O2. Based on this result, tangeretin in low concentration has a potential to reduce oxidative stress on HUVECs.  
The Effect of Reciting the Holy Qur’an to the Speaking Ability and Spirituality Level of Stroke Patient with Motor Aphasia Slamet Purnomo; Ikhlas Muhammad Jenie
Jurnal Keperawatan Padjadjaran Vol. 8 No. 3 (2020): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v8i3.1447

Abstract

Reading therapy is a stimulation effort to improve language function of a patient with motor aphasia. This study aim was to examine the effect of reading therapy using holy Qur’an to the speaking ability and spirituality level of stroke patient with aphasia. This experimental study used nonequivalent control group design with 20 persons as sample, divided to 10 persons as the intervention group and 10 persons in the control group used purposive sampling technique. Measurement of the speaking ability used Frenchay Aphasia Screening Test (FAST) questionnaire and spirituality level used Functional Assessment of Chronic Illness Therapy (FACIT) Sp 12 questionnaire. The Result was significant improvement of speaking ability in the intervention group with mean difference was mean±SD (1,60±1,075). Post-experimental difference test showed the difference of improvement of speaking ability between two groups, P=0,034. The spirituality level also significantly improved in the intervention group with mean difference was mean±SD (6,80±3,190). Post experimental difference test showed the improvement of spirituality level in both groups with P=0,005. This therapy can be used as a rehabilitation training activity independently at home to improve the speaking ability also as part of spiritual activity.
Cardivascular reactivity to earthquake Ikhlas Muhammad Jenie
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 9, No 1 (2009)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v9i1.1593

Abstract

Gempa bumi merupakan suatu stressor mental yang terjadi secara alamiah. Belum diketahui bagaimana respon kardiovaskular terhadap gempa bumi, berapa lama respon tersebut berlangsung, dan seberapa jauh akibat yang ditimbulkan oleh gempa bumi terhadap sistem kardiovaskular. Tujuan penulisan naskah ini adalah untuk mengetahui gambaran dan durasi serta potensial dari pengaruh reaktivitas Kardiovaskuler terhadap gempa bumi. Metode penelitian dilakukan dengan studi literatur terhadap penelitian-penelitian mengenai efek gempa bumi terhadap sistem kardiovaskular yang telah dipublikasikan pada MEDLINE. Tekanan darah dan frekuensi denyut jantung mulai berubah pada awal gempa bumi, dan kemudian naik sebesar 20% untuk tekanan darah sistolik, 46% untuk tekanan darah diastolik, dan 79% untuk frekuensi denyutjantung. Tingginya tekanan darah tersebut bertahan 1-2 minggu pasca gampa bumi, kemudian turun secara bertahap dalam kurun waktu 2 minggu. Peningkatan tekanan darah memanjang hingga 2 bulan pada pasien-pasien dengan mikroalbuminuria. Sementara itu, peningkatan tekanan darah tidak begitu tajam pada pasien-pasien yang mengkonsumsi obat-obat a- dan P-bloker Frekuensi denyut jantung kembali ke nilai awal lebih cepat daripada tekanan darah. Kejadian infark miokard meningkat 3 kali lipat penduduk yang tinggal dekat dengan pusat gempa daripada penduduk yang tinggal jauh dari pusat gempa. Terdapat hiperreaktivitas kardiovaskular terhadap gempa bumi. Hiperreaktivitas kardiovaskular terhadap gempa bumi tersebut bersifat akut dan berpotensi menimbulkan komplikasi infark miokard.Earthquake is a naturally occurring mental challenge. It potentially exerts adverse effects on the cardiovascular system, thus may contribute to the development of cardiovascular diseases. To know pattern and duration of the effect of earthquake on cardiovascular reactivity, and to know the potential effect of earthquake on the cardiovascular system. We did literature search on studies published in MEDLINE database that reported changes in cardiovascular parameters among subjects lived in earthquake affected area. The result of blood pressure and heart rate started to change at the initial trembling preceded the earthquake. Then at the strongest shock, systolic blood pressure increased 20%, diastolic blood pressure rose 46%, and heartbeat was up to 79%. Blood pressure remained high in 1-2 weeks after the quake. It then gradually returned to the baseline by 4 weeks (3 - 5 weeks) after the disaster. This increased blood pressure was prolonged for at least until 2 months aftermath in patients with microalbuminuria. However, it was less pronounced in patients who treated with a- and /3-blocker. The heart rate returned to the baseline level more promptly than the blood pressure. The events of myocardial infarction increased 3-fold in people who lived close to the epicentre. The conclution is cardiovascular hyperreactivity to earthquake has cardiac and vascular pattern. Exaggerated cardiovascular reactivity to earthquake is short term response. Cardiovascular reactivity to earthquake potentially leads to myocardial infarction.
Hubungan antara Riwayat Keluarga Hipertensi dengan Tekanan Darah setelah Berolahraga Isotonik pada Dewasa Muda Normotensif Ikhlas Muhammad Jenie; Sisti Meiryisha
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 9, No 1 (s) (2009)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v9i1 (s).1627

Abstract

Hypertension is divided into primary and secondary hypertension according to the causes. A secondary hypertension is caused by another disease, while a primary hypertension has an unknown cause but other factors such as genes and environmental issues can cause primary hypertension. The aim of this articles is to give a feature about blood pressure respons after exercise on young mature normotensive that have a family history of hypertension. The research design is a mixed semi-experimental method. The numbers of subjects are 45 people, divided in two groups. The first group consists of 23 people who have a family history of hypertension, and the second group consists of 22 people don ’t have a family history of hypertension. Every subject does an isotonic exercise using an ergometer cycle for 6 minutes. Before, during and after the exercise, the subject’s systole, diastole, and heart rates are measured. The comparison heart rate between the two groups was significant before (p=0,004), during (p=0,005), and after (p=0,002) isotonic exercise, and so did the increasing diastole pressure (p=0,030), no significant systole and diastole pressure results between the two groups in before, during, and after the exercise. The increasing of heart rate and diastole pressure, and also the recovery of heart rate, systole and diastole pressures did not differ between the two groups. It can concluded that familial history of hypertension influence the heart rate before, during, and after isotonic exercise, and also influence the increasing of systole pressure in normotensive young adults.Penyakit kardiovaskular adalah penyakit yang banyak menyebabkan kematian di Indonesia, salah satunya adalah hipertensi. Hipertensi adalah apabila tekanan darah sistolik mencapai 140 mm Hg atau lebih atau tekanan darah diastolik melebihi 90 mm Hg atau lebih. Hipertensi menurut penyebabnya digolongkan menjadi hipertensi primer dan sekunder. Hipertensi sekunder disebabkan oleh penyakit lain sedangkan hipertensi primer sampai sekarang belum diketahui penyebabnya akan tetapi faktor yang berperan adalah faktor genetik dan lingkungan. Tujuan makalah ini untuk memberi gambaran tentang respon tekanan darah setelah berolahraga isotonik pada dewasa muda normotensif yang memiliki riwayat keluarga hipertensi. Penelitian ini menggunakan metode semi experimental mixed design. Subjek 45 orang dibagi dua kelompok, yaitu kelompok satu 23 orang subjek memiliki riwayat keluarga hipertensi dan kelompok dua 22 orang subjek tidak memiliki riwayat keluarga hipertensi. Semua subjek melakukan olahraga isotonik dengan sepeda ergometer selama 6 menit, kemudian tekanan darah sistolik, tekanan darah diastolik, dan frekuensi denyut nadi diukur pada waktu sebelum, saat, dan setelah berolahraga. Peningkatan serta pemulihan tekanan darah sistolik, tekanan darah diastolik, dan frekuensi denyut nadi juga diukur. Didapatkan perbedaan yang bermakna antara kedua kelompok pada frekuensi denyut nadi sebelum (p=0,004), saat (p=0,005), dan setelah berolahraga (0,002) serta peningkatan tekanan darah sistolik (p=0,030), tidak ditemukan perbedaan yang bermakna antara kedua kelompok pada tekanan darah sistolik dan diastolik sebelum, saat, dan setelah berolahraga. Pada peningkatan tekanan darah diastolik dan frekuensi denyut nadi serta pemulihan pada tekanan darah sistolik, diastolik, dan frekuensi denyut nadi juga tidak ada perbedaan yang bermakna antara kedua kelompok. Disimpulkan bahwa riwayat keluarga hipertensi mempengaruhi frekuensi denyut nadi sebelum, saat, dan setelah berolahraga serta peningkatan tekanan darah sistolik pada dewasa muda normotensif.
Hubungan antara Indeks Massa Tubuh dengan Tekanan Intraokular pada Subyek Normotensif Gindah Ratu Priyasa Purnamasari; Ikhlas Muhammad Jenie
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 9, No 2 (s) (2009)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v9i2 (s).1611

Abstract

Recent people’s life style tends to be imbalance in input and output energy that results in obesity. Obesity is a risk factor of several diseases. Recently, obesity, as well as high blood pressure, is associated with glaucoma. The aim of this research is to know correlation between body mass index and intraocular pressure in normotensive people. This was an observational cross sectional study done to outpatient in Ophthalmology Polyclinic, Wonosobo District Hospital, along August - December 2008. Inclusion criteria were people aged between 30-55years old with normal blood pressure (systolic 139 mmHg, diastolic 89 mmHg). The exclusion criteria were people who had history of cardiovascular diseases, diagnosed of having glaucoma before, had contraindication to tonometry use, consumed drugs affecting cardiovascular system, and had family history of cardiovascular, kidney, liver, and lungs diseases. Body weight and body height were measured using weight and height scale (SMIC003), body mass index was calculated using formula, blood pressure was measured in lying position using sphygmomanometer (Spirit CK-101C) and stethoscope (3M Littmann Classic II SE) and intraocular pressure using tonometry Schiotz by an ophthalmologist. Data was analyzed using Pearson Correlation with p 0.05 as level of significance and One Way Anova. As many as 51 subjects joined the study. This study found moderate correlation between intraocular pressure and body mass index. Body weight as a component of body mass index has a borderline correlation with intraocular pressure. Besides, it showed that intraocular pressure in each underweight, normal, and overweight subjects simultaneously increase with increasing of body mass index. It is concluded that there is correlation between body mass index and intraocular pressure in normotensive subjects.Gaya hidup masyarakat modern yang cenderung tak seimbang dalam hal input dan output energi dapat menimbulkan obesitas. Baru-baru ini diketahui bahwa obesitas, sama halnya dengan tekanan darah tinggi, berhubungan dengan glaukoma. Jenis penelitian ini adalah penelitian observasional cross sectional yang dilakukan pada pasien rawat jalan di poli mata RSUD Wonosobo selama bulan Agustus-Desember 2008. Kriteria inklusi penelitian ini yaitu pasien yang berusia 30-55 tahun, bertekanan darah normal (tekanan sistolik 139 mmHg, dan tekanan diastolik 89 mmHg). Kriteria eksklusi penelitian ini yaitu pasien yang mempunyai riwayat penyakit kardiovaskular, terdiagnosis glaukoma sebelumnya, mempunyai kontraindikasi terhadap pemakaian tonometri, mengkonsumsi obat-obatan yang dapat mempengaruhi sistem kardiovaskular, dan memiliki riwayat keluarga berpenyakit kardiovaskular, ginjal, hati, dan paru-paru. Berat badan dan tinggi badan diukur dengan alat ukur berat dan tinggi badan (SMIC003), indeks massa tubuh dihitung berdasarkan rumus IMT = Berat Badan (kg)/ Tinggi Badan2 (m2), tekanan darah diukur pada posisi berbaring dengan sphygmomanometer (Spirit CK-101C) dan stethoscope (3M Littmann Classic II SE), serta tekanan intraokular diukur dengan tonometri Schiotz oleh seorang dokter spesialis mata. Data yang diperoleh kemudian dianalisis menggunakan Pearson Correlation dengan p 0.05 sebagai nilai signifikansi dan One Way Anova. Penelitian pada subyek sebanyak 51 orang ini mendapatkan hasil bahwa terdapat korelasi yang sedang antara indeks massa tubuh dengan tekanan intraokular. Selain itu, berat badan yang merupakan komponen dari indeks massa tubuh mempunyai korelasi yang rendah. Tekanan intraokular pada masing-masing kelompok underweight, normal, dan overweight meningkat seiring dengan peningkatan indeks massa tubuh (IMT). Dapat disimpulkan bahwa terdapat korelasi antara tekanan intraokular dengan indeks massa tubuh pada subyek normotensif.
Captopril Mencegah Stres Oksidatif pada Tikus Wistar Jantan dengan Diet Tinggi Lemak Ikhlas Muhammad Jenie; Rizki Afrian; Barii Hafidz Pramono
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 16, No 1 (2016): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v16i1.4723

Abstract

Stres oksidatif berperan dalam terjadinya penyakit-penyakit kardiovaskular. Stres oksidatif ditandai dengan peningkatan radikal bebas dan penurunan sistem antioksidan. Sumber utama radikal bebas pada sirkulasi adalah enzim NAD(P)H oksidase. Enzim tersebut dimodulasi oleh angiotensin II. Angiotensin II dihasilkan dari konversi Angiotensin I oleh enzim angiotensin converting enzyme (ACE). Timbul pertanyaan apakah pemberian captopril, suatu penghambat ACE, dapat mencegah stres oksidatif. Untuk itu dilakukan penelitian pra-eksperimental pada hewan coba dengan rancangan post test only measurement. Sebanyak 24 ekor tikus Wistar jantan dikelompokkan ke dalam 3 kelompok: kelompok I mendapat diet normal 20g/hr, kelompok II diet tinggi lemak (10%) 20g/hr dan kelompok III diet tinggi lemak (10%) 20g/hr dan captopril 50 mg/kgBB/hr. Perlakuan diberikan selama 2 bulan. Variabel yang diukur adalah berat badan, kadar kolesterol total, kadar hidrogen peroksida (H2O2) dan histopatologi aorta. Data dianalisis dengan ANOVA satu arah. Berat badan tikus antarkelompok tidak berbeda bermakna pada awal dan akhir perlakuan. Kadar kolesterol total antarkelompok berbeda bermakna, dengan kadar kolesterol total pada tikus kelompok III lebih rendah secara bermakna daripada kelompok I dan II. Kadar H2O2 antarkelompok berbeda bermakna, dengan kadar H2O2) pada tikus kelompok II lebih tinggi secara bermakna daripada kelompok I dan III. Pada pemeriksaan histopatologi, lesi aterosklerotik ditemukan pada kelompok II dan III. Disimpulkan bahwa pemberian captoprildapat mencegah stres oksidatif pada tikus Wistar jantan dengan diet tinggi lemak.  
PENGARUH KOMBINASI VITAMIN ORAL B1, B6 DAN B12 TERHADAP WAKTU REAKSI PADA SUBJEK DEWASA MUDA YANG SEHAT: STUDI ACAK TERKENDALI Imaniar Ranti; Ikhlas Muhammad Jenie
Biomedika Vol 13, No 1 (2021): Biomedika Februari 2021
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v13i1.9883

Abstract

ABSTRAKWaktu reaksi adalah waktu yang diperlukan oleh mahluk hidup untuk berespon secara sengaja terhadap stimulus yang diberikan. Waktu reaksi ini mampu menunjukkan kemampuan koordinasi sistem saraf motorik dan sensorik.  Waktu reaksi akan menurun saat terjadi penurunan fungsi sistem saraf. Salah satu vitamin yang dapat menjaga fungsi saraf adalah  kombinasi vitamin oral B1, B6 dan B12. Penelitian ini bertujuan untuk mengkaji efek pemberian vitamin oral B1, B6, dan B12 terhadap waktu reaksi. Desain penelitian menggunakan uji acak terkendali double blind.  Subyek sebanyak 20 orang laki-laki dan perempuan usia 18-20 tahun, yang terbagi secara acak 10 orang sebagai kelompok intervensi dan 10 orang sebagai kelompok kontrol.  Kombinasi vitamin oral B1 100 mg, B6 200 mg dan B12 200 mcg diberikan dalam bentuk kapsul dan diminum satu kali sehari selama 14 hari.  Subyek kelompok kontrol diberi kapsul yang berisi amylum lactose sebagai plasebo.  Pada hari ke-14, dilakukan pengukuran waktu reaksi sederhana dan waktu reaksi pilihan menggunakan alat pengukur kecepatan respon.  Hasil penelitian ini menunjukkan bahwa tidak ada perbedaan bermakna waktu reaksi sederhana dan waktu reaksi pilihan antara kelompok intervensi dan kelompok kontrol.  Akan tetapi, pada sub analisis berdasarkan gender, subyek perempuan kelompok intervensi mempunyai waktu reaksi pilihan yang lebih cepat dibandingkan kontrol. Kata Kunci: Waktu Reaksi, Kombinasi Vitamin Oral B1, B6, B12, Uji Acak TerkendaliABSTRACTReaction time is the time it takes for organisme to respond the given stimulus voluntarily. This reaction time is a good indicator of sensorimotor nervous system coordination. The reaction time will decrease when there is a decrease in nervous system function. One of the vitamins that can maintain nerve function is an combination of oral vitamins B1, B6 and B12. This study aimed to examine the effect of oral vitamins B1, B6, and B12 on reaction time. The study design used a double blind randomized controlled trial. Subjects were 20 men and women aged 18-20 years, which were randomly divided 10 people as the intervention group and 10 people as the control group. The combination of oral vitamins B1 100 mg, B6 200 mg and B12 200 mcg were given in capsule form and taken once a day for 14 days. The control group subjects were given a capsule containing amylum lactose as a placebo. On day 14th, a simple and selected reaction time was measured using a response velocity measuring device. The results of this study indicate that there were no significant difference in simple and selected reaction time between the intervention group and the control group. In a further analysis stratified by gender, female subjects in the intervention group had a faster selected reaction time than controls.   Keywords: Reaction Time, Oral Vitamin B1, B6, B12, Randomized Controlled Trial
Latihan Pernapasan Diafragma Meningkatkan Arus Puncak Ekspirasi (APE) dan Menurunkan Frekuensi Kekambuhan Pasien Asma Dian Kartikasari; Ikhlas Muhammad Jenie; Yanuar Primanda
Jurnal Keperawatan Indonesia Vol 22, No 1 (2019): March
Publisher : Faculty of Nursing Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.7454/jki.v22i1.691

Abstract

 Salah satu penatalaksanaan asma yaitu latihan pernapasan diafragma yang dapat meningkatkan fungsi paru pasien asma. Tujuan penelitian untuk menguji pengaruh latihan pernapasan diafragma terhadap peningkatan Arus Puncak Ekspirasi (APE) dan penurunan frekuensi kekambuhan pasien asma. Penelitian true experiment pretest-posttest with control group melibatkan 28 subyek penelitian secara random. Subyek dibagi menjadi kelompok intervensi dan kelompok kontrol melalui randomisasi sejumlah 14 orang untuk masing-masing kelompok. Pengukuran APE menggunakan peak flow meter dan frekuensi kekambuhan dicatat dengan lembar catatan observasi. Hasil penelitian terdapat perbedaan yang signifikan rerata selisih APE kelompok intervensi (mean 126,43±22,05 L/menit) dan kelompok kontrol (mean 52,14±56,45 L/menit) dengan p 0,001, serta terdapat perbedaan yang signifikan rerata selisih frekuensi kekambuhan kelompok intervensi (mean 1,29±0,61) dan kelompok kontrol (mean 0,79±0,57) dengan p 0,038. Latihan pernapasan diafragma menjadi pertimbangan dalam penatalaksanaan pasien asma. Kata kunci: arus puncak ekspirasi, asma, frekuensi kekambuhan, latihan pernapasan diafragma  AbstractEffect of Diaphragmatic Breathing Exercises on Peak Expiratory Flow Rate (PEFR) Enhancement and The Mild-Moderate Asthma Patients’ Relapse Frequency Reduction. One of the management of asthma is diaphragmatic breathing exercises that could improve lung function of asthma patients. The objective of the study was to examine the effect of diaphragmatic breathing exercises on Peak Expiratory Flow Rate (PEFR) and decreased frequency of mild-moderate asthma relapse on the patients. True experiment method pretest-posttest with control group was applied in this study with involved 28 random research subject. Subjects were divided into intervention groups and control groups through randomization of 14 people for each group. PEFR measurements using peak flow meter and relapse frequency were recorded with an observation note sheet. There was a significant difference of difference PEFR mean between intervention groups (mean 126.43±22.05) and control group (mean 52.14±56.45) with p 0.001. There was a significant difference of difference mean frequency between intervention group (mean 1.29±0.61) and control group (mean 0.79±0.57) with p 0.038. Diaphragmatic breathing exercise is a consideration in the management of asthma patients.Keywords: asthma, diaphragmatic breathing exercises, frequency of recurrence, peak expiratory flow rat
Co-Authors -, Praseno Adi, Danisworo K. Afrian, Rizki Astuti, Yoni Awisarita , Wiwara Barii Hafidz Pramono Budi Mulyono Dian Kartikasari Dian Kartikasari Gindah Ratu Priyasa Purnamasari Haruma Anggraini Muflikhasari Ianah Al Azizah Imaniar Ranti Irfan Muris Setiawan Joni Krismanto Kaslinda Nur Umifa Kusumo, Mahendro Prasetyo Lutfi Putra Perdana Marsetyawan HNE Soesatyo Maya Um Husna Meiryisha, Sisti Muhammad Herjuna Nurliana Achmad, Nurliana Pramono, Barii Hafidz Purnamasari, Gindah Ratu Priyasa Ranti, Imaniar Riris Istighfari Jenie Rizki Afrian Rosefani Intan Indraswari Sisti Meiryisha Slamet Purnomo Soedjono Aswin Sri Kadarsih Soejono Yanuar Primanda Zulkhah Noor Zulkhah Noor