Claim Missing Document
Check
Articles

Found 13 Documents
Search

CELLULOSE NANOCRYSTALS BASED ON PINEAPPLE LEAF FIBERS IN HEMOPERFUSION APPLICATIONS FOR CREATININE REMOVAL: BATCH METHOD ADSORPTION STUDY Raharjo, Yanuardi; Darmokoesoemo, Handoko; Fetty, Amelia Julia Tria; Aziz, Rizky Abdul; Salsabila, Fara; Ishma, Ervina Fadhilatul
Jurnal Kimia Riset Vol. 9 No. 2 (2024): December
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v9i2.65046

Abstract

Kidney failure is a major global cause of mortality, often resulting from the buildup of uremic toxins like creatinine. Creatinine serves as an indicator for assessing treatment needs in kidney failure patients. Hemoperfusion, a treatment based on the adsorption of toxins, has shown promise when using cellulose nanocrystals (CNCs) as adsorbents. CNCs derived from pineapple leaf fibers offer unique advantages due to their abundance of active sites, high adsorption capacity, and strong binding affinity. This study investigates the efficiency of CNCs in reducing creatinine levels, with the reduction attributed to the binding of creatinine to CNC hydroxyl groups. Characterization of CNCs was performed using PSA, XRD, FTIR, and SEM-EDX techniques, while the residual creatinine was quantified via UV-Vis spectrophotometry, utilizing a picric acid complex under alkaline conditions and measured at 485 nm. Optimal conditions were found with a stirring speed of 210 rpm, 120-minute contact time, and 10 mg/L creatinine concentration, resulting in an adsorption capacity (Qads) of 2.572 mg/g. The CNC adsorbent demonstrated hemocompatibility, with an APTT blood coagulation time of 31.3 seconds. These findings suggest that CNCs could be highly effective in developing safer, efficient hemoperfusion systems for managing kidney failure.
Pemanfaatan Nanokitosan Sebagai Coating Agent dalam Pembuatan Pupuk NPK Berbasis Control Release Fertilizer Sastra, Richad Ade; Adiarto, Totok; Prasetyo, Antonius Budi; Darmokoesoemo, Handoko; Putri, Devi Indrasari Mustopa
Eksergi Vol 20 No 3 (2023)
Publisher : Prodi Teknik Kimia, Fakultas Teknik Industri, UPN "Veteran" Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31315/e.v20i3.10699

Abstract

Kitosan merupakan biopolimer yang terdiri atas monomer glukosamin serta memiliki potensi sangat besar untuk dikembangkan sebagai biomaterial. Berdasarkan karakternya, kitosan larut dalam asam lemah dan tidak larut dalam air. Pada penelitian ini, kitosan dimodifikasi menjadi ukuran nano (nanokitosan) untuk meningkatkan kapabilitasnya sebagai membran dan digunakan sebagai coating agent dalam pembuatan pupuk NPK yang berbasis Control Release Fertilizer. Sintesis nanokitosan dilakukan dengan metode gelasi ionik dengan memberikan variasi pada lama pengadukan dan konsentrasi crosslinker. Variasi lama waktu pengadukan yang diberikan adalah 5 menit, 10 menit, dan 15 menit. Crosslinker yang digunakan dalam penelitian ini adalah Sodium Tripolyphosphate (STPP) dengan variasi konsentrasi 0,2%; 0,25%; 0,3%. Dari hasil uji release yang dilakukan, didapatkan nanokitosan dengan variasi lama pengadukan 15 menit dengan konsentrasi STPP 0,3% sebagai variasi yang paling optimal dengan release paling kecil. Melalui karakterisasi PSA, didapatkan ukuran nanokitosan tersebut sebesar 202,1 nm, dengan bentuk morfologi yang berbentuk bulatan teraglomerasi pada hasil SEM. Karakterisasi XRD yang didapatkan menunjukkan bahwa partikel bersifat amorf. Sedangkan pada hasil FTIR, didapatkan perbedaan vibrasi antara kitosan dengan nanokitosan pada bagian ikatan crosslink yang terbentuk.
Increasing Production, Improving Product Quality, and Empowering the Cracker Entrepreneur Group in Ngelom Pesantren Village A'yuni, Qurrota; Widati, Alfa Akustia; Raharjo, Yanuardi; Pudjiastuti, Pratiwi; Adiarto, Tokok; Harsini, Muji; Prasetyo, A. Budi; Supriyanto, Ganden; Darmokoesoemo, Handoko; Izzah, Adiba Naila; Haula', Hamizah; Hermawan, Hamzah Hilmy; Rizqullah, Almaysh Haidar
Agrokreatif: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 12 No. 1 (2026): Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/agrokreatif.12.1.139-150

Abstract

This community service aims to assist by disseminating technology related to production equipment, which will help increase both the quantity and quality of products. Additionally, the program offers training on oil quality and teaches how to process waste cooking oil into soap. This community service activity is a way to achieve SDGs in the Decent Work and Economic Growth category through Small Entrepreneur and the Rural Economy. The activities were held in Ngelom Pesantren Village from April until September 2023 to overcome the priority problems that exist in the cracker entrepreneur group. The participants of this activity were a group of cracker entrepreneurs in Ngelom Pesantren Village, totaling 30 participants. Activities were carried out through research methods, workshops, and procurement of tools to improve the production process and quality of cracker products. The workshop topics covered halal certification of food products, oil quality standards, and making soap from waste cooking oil. The survey results showed that participants had a satisfaction level of 92% towards the activities and 93% towards the procurement of tools provided, and the production increased by 202.78%. In addition, the crackers are less greasy and the packaging is well-sealed, which can improve the quality of cracker products.