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The Effect of Adherence to Antihypertensive Therapy and Cardiovascular Risk Among Hypertensive Patients in Purworejo Regency Arwinda, Prili; Virginia, Dita Maria; Hendra, Phebe
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 2 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007334

Abstract

Uncontrolled hypertension will increase mortality and morbidity rates. The adherence is an important factor in controlling blood pressure. Uncontrolled blood pressure will affect cardiovascular risk. Therefore, hypertensive patients must comply with taking medication to control blood pressure and cardiovascular risk. This study was an analytical observational study with a cross-sectional design. A total of 85 respondents who met the inclusion criteria were measured for adherence using the MPR (Medication Possession Ratio) method and the MARS-5 (Medication Adherence Report Scale-5) questionnaire.  A patient who had blood pressure 140/90 mmHg was categorized as controlled hypertension. The cardiovascular risk was measured using the ACC/AHA criteria method. Data were analyzed using chi-square tests and odds ratio (OR) with 95% confidence interval (CI) and p0.05 considered significant. This study showed that there was a significant association between adherence to antihypertensive therapy to controlled blood pressure, either according to MPR (OR=18.262; 95%CI=5.259-63.412; p=0.000) and MARS-5 (OR=31.607; 95%CI=8.170-122.277; p=0.000). A significant association was found between antihypertensive adherence and cardiovascular risk, either according to MPR (OR=3.733; 95%CI=1.269-10.983; p=0.020) and MARS-5 (OR=9.000; 95%CI=2.702-29.983; p=0.000). Therefore, this study concludes a significant relationship between antihypertensive adherence to controlled blood pressure and cardiovascular risk in Purworejo Regency.
The Relationship of Medication Adherence to Controlled HbA1c and ASCVD Risk in Type II Diabetes Mellitus Patients in Minggir Primary Health Care Dewita, Aquina Nino Rama Dhanti; Hendra, Phebe; Virginia, Dita Maria
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 1 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007464

Abstract

Type II diabetes mellitus (DM) therapy can be evaluated from the controlled HbA1c. Another aspect that needs to be controlled in patients with DM is lipid levels. Lipid levels should be controlled in a patient with type II DM to prevent atherosclerotic cardiovascular disease (ASCVD). The study was conducted to determine the relationship between medication adherence with controlled HbA1c and ASCVD risk in patients with type II DM. The study was an analytical observational study with a cross-sectional research design used to examine the relationship between medication adherence with controlled HbA1c and ASCVD risk. Our respondents were patients following a chronic disease management program at Minggir Primary Health Care. The level of medication adherence was measured using the Medication Adherence Report questionnaires. The ASCVD risk was measured using the American College of Cardiology/American Heart Association tools. The chi-squared test was applied to determine the relationship between medication adherence with HbA1c values and ASCVD risk in patients with type II DM. Most patients with type II DM had high medication adherence (60%), controlled HbA1c values (56.4%), and high ASCVD risk (70.9%). There was no significant relationship between medication adherence in type II DM patients with controlled HbA1c values and ASCVD risk.
Analisis Faktor Perilaku Swamedikasi Gout Arthritis : Kajian Persepsi Masyarakat di Kabupaten Ende Hane, Angelina Rosari; Hendra, Phebe
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 9 (2025): : JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i9.4775

Abstract

Swamedikasi merupakan upaya masyarakat dalam menangani penyakit ringan secara mandiri dengan menggunakan obat bebas yang aman tanpa resep dokter. Faktor yang memengaruhi perilaku ini antara lain tingginya biaya pengobatan, kurangnya pengetahuan kesehatan, keterjangkauan obat, keterbatasan fasilitas medis, serta pengaruh lingkungan. Penelitian ini bertujuan menganalisis faktor yang berkontribusi terhadap perilaku swamedikasi gout arthritis dengan menggunakan tinjauan Theory of Planned Behaviour (TPB). Metode penelitian yang digunakan adalah observasional analitik dengan pendekatan cross sectional. Responden adalah masyarakat Kabupaten Ende yang melakukan swamedikasi gout arthritis. Variabel bebas terdiri dari konstruk TPB yaitu attitude (sikap), subjective norms (norma subjektif), dan perceived behaviour control, sedangkan variabel terikatnya adalah intention (niat). Instrumen penelitian berupa kuesioner yang disusun berdasarkan konstruk TPB dan diisi langsung oleh responden. Hasil penelitian terhadap 105 responden menunjukkan bahwa piroxicam (66,7%) merupakan obat yang paling banyak dibeli dibandingkan allopurinol dan natrium diklofenak. Sebagian besar responden melakukan pembelian obat 2–3 kali dalam sebulan (45,7%). Analisis hubungan menunjukkan adanya pengaruh signifikan antara subjective norms dengan intention (p=0,030; p<0,05). Faktor yang paling berkontribusi terhadap perilaku swamedikasi adalah subjective norms, diikuti oleh perceived behaviour control.
Pemberdayaan Kesehatan Masyarakat Dusun Kemantren II Semawung Melalui Edukasi Pengelolaan Obat Hendra, Phebe; Riswanto, Florentinus Dika Octa; Setyani, Wahyuning; Julianus, Jeffry; Rajagukguk, ⁠Greysianita; Santi , Nyoman Pradnya Yoni Meytri; Bramantyo , Dominicus Adyatma; Siallagan , Angela Meirella; Putri , Elsha Tiany
Rengganis Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2025): November 2025
Publisher : Pendidikan Matematika, FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/rengganis.v5i2.608

Abstract

The misuse of drugs is a major health issue in Indonesia, largely due to a lack of understanding about proper drug management. Knowledge of correct medication use is essential to prevent administration errors. Key issues in Dusun Kemantren II, Semawung Village include a limited understanding of medication usage and inadequate drug storage systems. Engaging the community with information on effective drug management is essential to address this. This community service initiative aims to improve drug management knowledge in Dusun Kemantren II, Semawung Village, Purworejo District. The activity was carried out on May 4, 2025, with 23 participants. Evaluation results showed increased participants' knowledge after the education, based on average pre-test and post-test scores. This program successfully improved public knowledge and awareness regarding the importance of proper drug management. It provided practical means, such as medicine boxes, to support the implementation of this knowledge at the household level.