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Exposure of Murattal Al-Quran Audio Enhances Cisplatin Activity on Growth Inhibition and Cell Cycle Modulation on Hela Cells Mutiah, Roihatul; Mustofa, Muhammad Ragib; Indrawijaya, Yen Yen Ari; Hakim, Abdul; Annisa, Rahmi; Susanti, Nurlaili; Nashichuddin, Ach; Zainuddin, Muhammad
Indonesian Journal of Cancer Chemoprevention Vol 10, No 2 (2019)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev10iss2pp71-79

Abstract

Cancer is a disease characterized by abnormal cell mechanisms. The development of alternative cancer treatments is still needed. One of them is the music therapy. The music therapy uses sound vibrations to improve healing. Al-Quran, the Holy book of muslims, recites with measured recitation produces beautiful tones. Reading and recitating of Al-Quran is an important form of worship for which a Muslim can expect reward and benefit in the Hereafter. Al-Fatihah is one of surahs in Al-Qur'an that is often read by Muslims and used as a prayer for healing. The purpose of this study was to determine the effect of cytotoxic activity and cell cycle modulation on Hela cells with exposure of murattal Al-Quran and cisplatin combination. Audio exposure murattal Al-Fatihah and its combination with cisplatin to HeLa cells were tested using the MTT method assay. Induction of apoptosis and modulation of cell cycle evaluated by flow cytometry method. Treatment used 30 minutes Audio Murattal (AM), Cisplatin 10 µg/mL (Cis), and the combination of AM + Cis caused a decrease in the viability of HeLa cells respectively 80.14%, 69.86%, and 64.32%. The results of flow cytometry explained that in treatment of AM there was inhibition in the G2-M phase and induction of apoptosis in the M5 phase. Whereas in treatment AM + Cis inhibition occurs in the S, G2-M phase, and induction of apoptosis in the M5 phase. Audio Murattal Al-Quran presents cytotoxic effects on HeLa cells and to provide a synergistic impact on cisplatin so that disclosure therapy murattal can be recommended for supporting therapy in the treatment of cancer (supportive therapy).Keywords: Al-Quran, Audio murottal, HeLa Cells, Cell Viability, Flow cytometry
Digital Natives and the Call for Innovation in Arabic Language Education Nashichuddin, Achmad; Taufiqurrochman, R.; Salam, Nur
Kitaba Vol 3, No 3 (2025): KITABA
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/kitaba.v3i3.36997

Abstract

Abstract: Today’s graduate students in Arabic language education are unmistakably digital natives—predominantly young women (70.6%) aged 21–25, graduates of Islamic higher education institutions across Indonesia, and deeply embedded in digital culture. This study explores their research interests, academic expectations, and aspirations through a structured survey of 51 newly enrolled master’s students at Maulana Malik Ibrahim State Islamic University (UIN Malang). Findings reveal a decisive shift in scholarly orientation: 37.3% identified “technology and media in Arabic language education” as their primary research interest, far surpassing traditional domains like linguistics or literature. Their call for innovation is not merely technological but pedagogical—they seek curricula that integrate digital tools, emphasize practical application, and align with 21st-century competencies. Simultaneously, a significant academic preparedness gap emerges: 72.5% requested intensive training in scholarly writing, and 64.7% demanded access to international journals, signalling a need for methodological scaffolding. Global aspirations are equally strong, with multiple students explicitly advocating for student exchange programs to Saudi Arabia, Malaysia, and Madinah. Thematic analysis of open-ended responses yielded five strategic priorities: (1) strengthening academic capacity, (2) advancing internationalization, (3) ensuring curriculum relevance in the digital era, (4) improving internal management, and (5) nurturing an Islamic scholarly vision that fuses linguistic mastery with civilizational mission. This study argues that the voices of digital-native students are not peripheral feedback but central diagnostic data for transforming Arabic language education into a dynamic, responsive, and globally engaged discipline in the Global South.