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Bilangan Kromatik Grap Commuting dan Non Commuting Grup Dihedral Rahayuningtyas, Handrini; Abdussakir, Abdussakir; Nashichuddin, Achmad
CAUCHY Vol 4, No 1 (2015): CAUCHY
Publisher : Mathematics Department, Maulana Malik Ibrahim State Islamic University of Malang

Commuting graph is a graph that has a set of points X and two different vertices to be connected directly if each commutative in G. Let G non abelian group and Z(G) is a center of G. Noncommuting graph is a graph which the the vertex is a set of G\Z(G) and two vertices x and y are adjacent if and only if xyâ‰ yx. The vertex colouring of G is giving k colour at the vertex, two vertices that are adjacent not given the same colour. Edge colouring of G is two edges that have common vertex are coloured with different colour. The smallest number k so that a graph can be coloured by assigning k colours to the vertex and edge called chromatic number. In this article, it is available the general formula of chromatic number of commuting and noncommuting graph of dihedral group

Wacana Khitan Perempuan Di Masyarakat Desa (Studi Di Masyarakat Desa Pager, Kecamatan Purwosari, Kabupaten Pasuruan) Nashichuddin, Ach.
ULUL ALBAB Jurnal Studi Islam Vol 4, No 1 (2003): Islamic Studies
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

This research aims to describe a discourse of female circumcision in Pager village, Purwosari district, Pasuruan. There are two discourses that are described in this research; discourse of fiqh text that consists of books written by Moslem scholar of Syafi'iyah and discourse of social context in the village. This research found that no all fiqh books, which are spread over in society explain about female circumcision. The explanation is only found in advanced fiqih books that seldom be touched by civil society. In fiqh books expressed that majority of Moslem scholar see that female circumcision is religious obligatory either for men and woman. For a while other minority Moslem scholar see that it is obliged to men and recommended to woman. There is a significant difference between the fiqih text and the social context in Pager in explaining the meaning of female circumcision practice. There are three factors that cause the difference; the social and cultural change in the society, the change of thought system in the society, and the lack of knowledge regarding the fiqih text that explains female circumcision.

Analisis Kandungan Logam Berat Cd, Hg, dan Pb Daun Semanggi (Marsilea crenata Presl.) di Desa Semen, Kecamatan Pagu, Kabupaten Kediri Ma'arif, Burhan; Muti'ah, Roihatul; Suryadinata, Arief; Nashichuddin, Ach; Karawid, Galih Elsy
Journal of Islamic Pharmacy Vol 5, No 2 (2020): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v5i2.9356

Semanggi (Marsilea crenata Presl.) berpotensi untuk diolah menjadi produk obat herbal karena khasiat yang dimilikinya. Namun, tanaman semanggi (Marsilea crenata Presl.) memiliki kemampuan fitoremediasi sehingga berdampak pada penimbunan logam berat yang berbahaya untuk kesehatan tubuh. Penelitian ini dilakukan untuk mengetahui kandungan logam berat Cd, Hg dan Pb pada daun semanggi di Kabupaten Kediri (Desa Semen, Kecamatan Pagu) untuk dibandingkan dengan Perka BPOM No. 12 tahun 2014 terkait batas logam berat untuk simplisia. Metode yang digunakan yaitu menggunakan Atomic Absorption Spectroscopy (AAS) pada sampel simplisia daun tanaman semanggi dan juga sampel tanah sebagai pembanding. Dari hasil pengujian sampel simplisia daun semanggi di Kabupaten Kediri (Desa Semen, Kecamatan Pagu) terdapat (Cd) dengan kadar 4,16 ppm. Hasil ini menunjukkan tidak memenuhi standar Perka BPOM No. 12 tahun 2014 karena melewati batas minimum Cd sebesar â‰¤ 0,3 ppm.

Implementasi Integrasi Islam dan Kedokteran Dalam Tugas Akhir Mahasiswa (Skripsi) Pada Fakultas Kedokteran dan Ilmu Kesehatan UIN Maulana Malik Ibrahim Malang Ach. Nashichuddin; Anita Andriya Ningsih; Nur Toifah
Journal of Islamic Medicine Vol 6, No 1 (2022): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2022
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v6i1.15690

Background: The integration of Islam and science is the process of unification of various branches of science that exist with an assumption that all components of science come from God, which can be implemented in the learning curriculum in all faculties, including the faculty of medicine and health Sciences in the doctor's education study program. To achieve the vision of realising an integrative doctorate education study program in combining science and Islam of international repute, the integration is implemented in several fields of Education and teaching, including writing the final student project (thesis). Objective : to know the concept of integration of Islam and medicine and its implementation in writing student thesis at the faculty of medicine in ptkin environment. Method: This study uses a qualitative descriptive model to describe the concept of Islamic integration and prayer and its implementation in student thesis in the Medical Education Study Program of the Faculty of Medicine and Health Sciences by sampling ten student thesis in 2020. The results of the study are: 1) The concept used in the integration of Islam and medicine in the final project of students is a model of integration of Islamic Science, which makes the Qur'an and Hadith the foundation of the development of medical science. 2) The concept of integration of Islam and Medicine set out in the thesis writing manual has not been implemented optimally because there are differences in the writing of integration concepts in their final project. Conclusion: The implementation of Islamic Integration and Medicine has not been conceptualized optimally in preparing the final student project (thesis) at the Faculty of Medicine and Health Sciences UIN Maulana Malik Ibrahim Malang. Keywords: Medicine, Integration, Islam

Sufism in Java: The Meeting Point Between Sufism and Javanese Mysticism Ach. Nashichuddin
el Harakah: Jurnal Budaya Islam Vol 8, No 1 (2006): EL HARAKAH
Publisher : UIN Maulana Malik Ibrahim Malang

Wali Songo is a clerical preacher who is not only an Islamic prophet but also a carrier of Sufism in Java. This paper reviews sufism in Wali Songo era and the meeting point between sufism and Javanese mysticism. Seen from their teachings, they are adherents of the flow of Sunni Sufism that many adopt the teachings of Imam Al-Ghazali. In developing their teachings they established an educational institution called pesantren, an educational institution which at the same time provides a dormitory as a residence for the santri. In spreading Islam they are easily accepted by the Javanese community. This cannot be separated from the teachings they developed, the teachings of Sufism which have similarities with the mystical teachings held by the people of Java. The meeting point between Sufism and Javanese mysticism is the main factor in the success of Wali Songo’s mission in Java. It results in Javanese Islam, a combination between Islamic teaching and Javanese culture. Wali Songo adalah seorang pengkhotbah klerus yang bukan hanya seorang nabi Islam tapi juga pembawa tasawuf di Jawa. Makalah ini mengulas sufisme di era Wali Songo dan titik temu antara sufisme dan mistisisme Jawa. Dilihat dari ajaran mereka, mereka menganut aliran tasawuf Sunni yang banyak mengadopsi ajaran Imam Al-Ghazali. Dalam mengembangkan ajaran mereka, mereka mendirikan sebuah institusi pendidikan yang disebut pesantren, sebuah institusi pendidikan yang pada saat yang sama menyediakan asrama sebagai tempat tinggal para santri. Dalam menyebarkan Islam mereka mudah diterima oleh masyarakat Jawa. Hal ini tak lepas dari ajaran yang mereka kembangkan, ajaran tasawuf yang memiliki kesamaan dengan ajaran mistik yang dipegang oleh masyarakat Jawa. Titik temu antara tasawuf dan mistisisme Jawa merupakan faktor utama dalam keberhasilan misi Wali Songo di Jawa. Ini menghasilkan Islam Jawa, kombinasi antara ajaran Islam dan budaya Jawa.

Analisis Dinamik Model Penyebaran Tumor Otak dengan Respon Sel Imun Resti Dwi Anggraini; Usman Pagalay; Achmad Nashichuddin
Jurnal Riset Mahasiswa Matematika Vol 1, No 3 (2022): Jurnal Riset Mahasiswa Matematika
Publisher : Mathematics Department, Maulana Malik Ibrahim State Islamic University of Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jrmm.v1i3.14339

The brain tumor distribution model with immune cell response is in the form of a non-linear system of ordinary differential equations with five equations. Each equation describes how immune cells in the brain, namely macrophages ( ), CD8+ T cells ( ), TGF- cytokines ( ) and IFN- ( ) cytokines interact with tumor cells, namely glioma cells ( ). From the calculation of the equilibrium point, the tumor cell-free conditions (DFE) and the endemic conditions (END) were obtained, in which tumor cells in long-term conditions were always present in the patient's brain. By using certain parameter values, it can be illustrated that the END condition is locally asymptotically stable while the DFE condition is locally unstable. This indicates that brain tumor cells, namely glioma cells ( ) will increase to their maximum value of 882650 cells and remain at that number from day 1000 onwards.

Analisis Dinamik Model Penyebaran Tumor Otak dengan Respon Sel Imun Anggraini, Resti Dwi; Pagalay, Usman; Nashichuddin, Achmad
Jurnal Riset Mahasiswa Matematika Vol 1, No 3 (2022): Jurnal Riset Mahasiswa Matematika
Publisher : Mathematics Department, Maulana Malik Ibrahim State Islamic University of Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jrmm.v1i3.14339

The brain tumor distribution model with immune cell response is in the form of a non-linear system of ordinary differential equations with five equations. Each equation describes how immune cells in the brain, namely macrophages ( ), CD8+ T cells ( ), TGF- cytokines ( ) and IFN- ( ) cytokines interact with tumor cells, namely glioma cells ( ). From the calculation of the equilibrium point, the tumor cell-free conditions (DFE) and the endemic conditions (END) were obtained, in which tumor cells in long-term conditions were always present in the patient's brain. By using certain parameter values, it can be illustrated that the END condition is locally asymptotically stable while the DFE condition is locally unstable. This indicates that brain tumor cells, namely glioma cells ( ) will increase to their maximum value of 882650 cells and remain at that number from day 1000 onwards.

Exposure of Murattal Al-Quran Audio Enhances Cisplatin Activity on Growth Inhibition and Cell Cycle Modulation on Hela Cells Mutiah, Roihatul; Mustofa, Muhammad Ragib; Indrawijaya, Yen Yen Ari; Hakim, Abdul; Annisa, Rahmi; Susanti, Nurlaili; Nashichuddin, Ach; Zainuddin, Muhammad
Indonesian Journal of Cancer Chemoprevention Vol 10, No 2 (2019)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev10iss2pp71-79

Cancer is a disease characterized by abnormal cell mechanisms. The development of alternative cancer treatments is still needed. One of them is the music therapy. The music therapy uses sound vibrations to improve healing. Al-Quran, the Holy book of muslims, recites with measured recitation produces beautiful tones. Reading and recitating of Al-Quran is an important form of worship for which a Muslim can expect reward and benefit in the Hereafter. Al-Fatihah is one of surahs in Al-Qur'an that is often read by Muslims and used as a prayer for healing. The purpose of this study was to determine the effect of cytotoxic activity and cell cycle modulation on Hela cells with exposure of murattal Al-Quran and cisplatin combination. Audio exposure murattal Al-Fatihah and its combination with cisplatin to HeLa cells were tested using the MTT method assay. Induction of apoptosis and modulation of cell cycle evaluated by flow cytometry method. Treatment used 30 minutes Audio Murattal (AM), Cisplatin 10 µg/mL (Cis), and the combination of AM + Cis caused a decrease in the viability of HeLa cells respectively 80.14%, 69.86%, and 64.32%. The results of flow cytometry explained that in treatment of AM there was inhibition in the G2-M phase and induction of apoptosis in the M5 phase. Whereas in treatment AM + Cis inhibition occurs in the S, G2-M phase, and induction of apoptosis in the M5 phase. Audio Murattal Al-Quran presents cytotoxic effects on HeLa cells and to provide a synergistic impact on cisplatin so that disclosure therapy murattal can be recommended for supporting therapy in the treatment of cancer (supportive therapy).Keywords: Al-Quran, Audio murottal, HeLa Cells, Cell Viability, Flow cytometry

The Impact of Neem Leaf Extract (Azadirachta indica) on renal hypoxia in Balb/C Mice Infected with Plasmodium berghei Rahmah, Zainabur; Religious, Tafakur Bagus; Akbar, Putri Wulan; Kosbandhono, Erryk; Amiruddin, Muhammad; Nashichuddin, Ach
The Avicenna Medical Journal Vol. 6 No. 2 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i2.46488

Background: Millions of people die from malaria every year in tropical areas, making it a severe public health concern. Plasmodium, a genus of protozoa with several species, is the main cause of the disease. Humans contract malaria when bitten by female Anopheles sp. mosquitoes. Malaria is one of the world's deadliest diseases. The WHO's 2020 World Malaria Report indicates that there were 229 million cases of malaria globally in 2019, with 409,000 fatalities resulting from the disease. In nine Southeast Asian countries, malaria is endemic. After India, Indonesia is the second most endemic region. Transcription factors such as the HIF-1α protein are produced by hypoxic cells. Patients with malaria have a blockage of the cytoaderenal pathway. Hypoxia occurs due to vascular disorders that prevent oxygen flow to the kidney tissue. Antimalarial drugs are developed in response to the lethal consequences of hypoxia. Methods: BALB/c mice aged sixteen weeks were infected with the Plasmodium berghei ANKA strain. For six days, the neem leaf 96% ethanol extract was administered orally at doses of 8 mg, 12 mg, and 16 mg. As comparisons, negative, positive, and healthy controls were also included. The kidneys were isolated, and the mice were surgically removed on the seventh day. HIF-2α expression in kidney tissue, which was measured immunohistochemically using Abcam's anti-HIF-2α (H1α67) ChIP Grade antibody, was a characteristic of kidney hypoxia. One-way ANOVA, post-hoc LSD, and Pearson correlation tests were used to assess the hypotheses. Results: Treatment with neem leaf extract significantly decreased oxygen levels (p<0.000). The correlation test showed a very strong relationship between neem leaf extract and HIF-2α expression in the kidney (r=16.057). Conclusion: Twelve milligrams of neem leaf extract can reduce the risk of renal hypoxia. Keywords: Neem leaves, malaria, degree of parasitemia, hypoxia, Azadirachta indica

Penerapan F-AHP dan MOORA dengan Matriks Terbobot dalam Menentukan Prioritas Kebutuhan Tenaga Kesehatan Adellia Fitria Marta Dewi; Turmudi Turmudi; Achmad Nashichuddin
Jurnal Riset Mahasiswa Matematika Vol 5, No 4 (2026): Jurnal Riset Mahasiswa Matematika
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jrmm.v5i4.42222

Penelitian ini menerapkan Fuzzy Analytic Hierarchy Process (F-AHP) dan Multi Objective Optimization on the Basis of Ratio Analysis (MOORA) untuk menentukan prioritas kebutuhan tenaga kesehatan pada 20 negara di wilayah Eropa dan Asia Tengah. Enam kriteria digunakan, yaitu jumlah dokter, perawat, bidan, dokter gigi, tenaga farmasi, dan luas daratan. Data diperoleh dari World Health Organization (WHO) dan Worldometer. Metode F-AHP digunakan untuk menentukan bobot kriteria melalui matriks perbandingan berpasangan berbasis Triangular Fuzzy Number (TFN), sedangkan MOORA digunakan untuk menghitung nilai preferensi dan peringkat alternatif melalui matriks terbobot. Hasil F-AHP menunjukkan bahwa jumlah dokter memiliki bobot tertinggi, diikuti jumlah perawat, bidan, dokter gigi, tenaga farmasi, dan luas daratan. Hasil MOORA menunjukkan bahwa San Marino, Andorra, dan Montenegro menjadi tiga alternatif dengan prioritas tertinggi. Temuan ini menunjukkan bahwa integrasi F-AHP dan MOORA dapat menghasilkan proses pemeringkatan yang sistematis dan terukur. Namun, interpretasi hasil tetap perlu mempertimbangkan bahwa data yang digunakan bersifat absolut dan belum memperhitungkan rasio tenaga kesehatan terhadap jumlah penduduk.

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