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The effectiveness of butterfly pea hydrogel film (Clitoria Ternatea) with chitosan and poly-vinyl-alcohol based as diabetic wound healing Wicita, Prisca Safriani; Daud, Rizka Puji Astuti; Sapiun, Zulfiayu; Yahya, Cindy; Wantaa, Nurunnisa; Mohamad, Fihrina; Imran, Arlan K.; Hartati, Hartati; Husain, Fadli
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 2 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i2.1483

Abstract

Butterfly pea possesses antioxidant activities with IC50 470 μg/ml of wound healing acceleration quality. Hydrogel for diabetic wound healing due to its physical characteristic that binds water, aside from its qualities that wets the surface and bio-compatibility in the body. This study aimed to identify effectivity test of hydrogel film preparation with butterfly pea (clitoria ternatea l.) Water extract for diabetic wound healing, employing true experimental method which involves 12 rats divided into 4 groups. The control group was treated without the Hydrogel (HET) or HET0 on hyperglycemic rats, HET1 (2%), HET2 (5%), and HET3 (7.5%). The findings revealed wounds treated with HET0 was healed in 9 days with 11.13 mm of diameter (100%), HET1 was healed in 6 days with 15.22 mm of diameter (100%), HET2 that was healed in 4 days with 11.29 mm of diameter (100%), and HET3 that was healed in 8 days with 9.05 mm of diameter (100%). It was concluded that the effectivity test revealed that the best formula is HET2 (5%) healed in 4 days with 11.29 mm of diameter in 100%.
PENYULUHAN KESEHATAN DAN DEMONSTRASI PRODUK MINUMAN FUNGSIONAL PADA SISWA SMA UNTUK PENCEGAHAN DINI DIABETES MELLITUS Hartati Hartati; Prisca S. Wicita; Fitriah Ayu Magfirah Yunus; Mahdalena Sy. Pakaya
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 2 (2025): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i2.29146

Abstract

Abstrak: Peningkatan prevalensi kasus diabetes melitus di Indonesia, khususnya di Provinsi Gorontalo menjadi salah satu alasan penting dalam upaya pencegahan diabetes mellitus sedini mungkin pada remaja untuk mencegah komplikasi jangka panjang yang dapat mengancam jiwa jika tidak ditangani dengan tepat. Salah satu upaya yang dapat dilakukan adalah melalui penyuluhan dan demonstrasi produk minuman fungsional bahan alam. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan dan keterampilan remaja terkait upaya pencegahan diabetes mellitus melalui pemanfaatan bahan alam sekitar. Kegiatan ini melibatkan 22 orang siswa SMA Negeri 1 Tilango yang berasal dari perwakilan kelas serta siswa yang aktif terlibat dalam kegiatan organisasi di sekolah. Berdasarkan hasil uji statistik pretest dan posttest diketahui bahwa terjadi peningkatan pengetahuan siswa dari 48.2% menjadi 93.6%. Selain itu, juga terdapat perwakilan siswa sebagai agent of change yang terampil dalam pembuatan produk minuman fungsional.Abstract: The increasing prevalence of diabetes mellitus cases in Indonesia, especially in Gorontalo Province, is one of the important reasons for efforts to prevent diabetes mellitus as early as possible in adolescents to prevent long-term complications that can be life-threatening if not treated properly. One of the efforts that can be done is through counseling and demonstration of natural functional beverage products. The purpose of this activity is to increase the knowledge and skills of adolescents related to efforts to prevent diabetes mellitus through the use of natural materials around them. This activity involved 22 students of SMA Negeri 1 Tilango who came from class representatives and students who were actively involved in organizational activities at school. Based on the results of the pretest and posttest statistical tests, it is known that there was an increase in student knowledge from 48.2% to 93.6%. In addition, there are also student representatives as agents of change who are skilled in making functional drinks.