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All Journal Jurnal Kedokteran Majalah Obstetri dan Ginekologi Health Notions Journal of Public Health Research and Community Health Development (JPH RECODE) AKSONA Folia Medica Indonesiana

Joni Wahyuhadi, Joni

Department Of Neuro-surgery, Faculty Of Medicine, Universitas Airlangga

Author-ID : 557697

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 13 Documents Claim Missing Document

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Korelasi Usia dan Jenis Kelamin dengan Angka Kejadian Meningioma Arlia Ayu Damayanti; Viskasari Pintoko Kalanjati; Joni Wahyuhadi
AKSONA Vol. 1 No. 1 (2021): JANUARY 2021
Publisher : Universitas Airlangga

Pendahuluan: Meningioma merupakan tumor otak primer yang berasal dari jaringan arakhnoid. Angka kejadian meningioma di Indonesia menunjukkan peningkatan dari tahun ke tahun. Selain mutasi gen supresor tumor, meningioma dapat dipengaruhi oleh faktor eksternal diantaranya usia dan jenis kelamin. Tujuan: Mengetahui hubungan antara usia dan jenis kelamin dengan angka kejadian meningioma pada pasien di RSUD Dr. Soetomo, Surabaya, Indonesia tahun 2018 berdasarkan derajat keganasannya. Metode: Penelitian ini merupakan studi observasional analitik cross-sectional retrospektif dari data sekunder lembar hasil pemeriksaan patologi anatomi pasien yang dirawat inap melalui SMF. Ilmu Bedah Saraf, RSUD Dr. Soetomo tahun 2018; data yang tidak lengkap akan dieksklusi. Analisis data dilakukan menggunakan uji Chi squre (SPSS 25) dengan tingkat signifikansi p <0,05. Hasil: Didapatkan 45 pasien meningioma yang sesuai dengan kriteria inklusi, dengan mayoritas perempuan (71%) pada kelompok usia 45 – 49 tahun (22,2%), WHO grade I (82%) dengan tipe histopatologi transisional (49%). Terdapat hubungan yang signifikan antara angka kejadian meningioma dengan kelompok usia tertentu (r = 0,718, p = 0,025), dan dengan jenis kelamin (r = 0,441, p = 0,002). Rasio perempuan dibanding laki- laki sebesar 1:2,36. Kesimpulan: Usia dan jenis kelamin berkorelasi erat dengan angka kejadianmeningioma.

Diffusion Weighted Imaging (DWI) Classification and Apparent Diffusion Coefficient (ADC) Value Tendency Based on Cerebral Glioma Grading in Patients at Dr. Soetomo General Academic Hospital in 2016-2020 Komang Wahyu Kurniawan; Sri Andreani Utomo; Joni Wahyuhadi
AKSONA Vol. 3 No. 1 (2023): JANUARY 2023
Publisher : Universitas Airlangga

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Highlight: Many studies conclude that the prognosis of gliomas can be determined using the DWI sequence and ADC value on MRI The correlation between DWI and ADC values with glioma grading is related to tumor cellularity, nuclear-cytoplasmic ratio, and extracellular space, which affect the movement of water molecules. ABSTRACT Introduction: Glioma grading is crucial to know its prognosis. Magnetic resonance imaging (MRI) is used as a preoperative examination that contains diffusion-weighted imaging (DWI) sequences confirmed by an apparent diffusion coefficient (ADC) value that helps assess tissue based on water diffusion. Objective: To prove the relationship between DWI and ADC values with cerebral glioma grading in patients at Dr. Soetomo General Academic Hospital in 2016—2020. Methods: This retrospective study collected medical records and MRI files in DICOM (Digital Imaging and Communications in Medicine) format. Gender, age, tumor histopathology, and glioma grading were collected. DWI and ADC values were obtained using the RadiAnt DICOM Viewer application. The data were analyzed using descriptive and analytical statistics. The chi-square test was used to analyze the relationship of DWI with glioma grading, and the spearman rank test was used to analyze the relationship of ADC value with glioma grading. Results: The majority of 35 patients were male (54.3%), aged 31–40 years old (22.9%), and the most common histopathology was glioblastoma (37.1%), WHO grade IV. On DWI, most low-grade glioma (LGG) patients showed unrestricted diffusion, and most high-grade glioma (HGG) patients showed restricted diffusion. The ADC value of HGG was lower than the ADC value of LGG. Statistical tests showed a relationship between DWI and glioma grading (p<0.05) and a relationship between the ADC value and glioma grading (p<0.05). Conclusion: There was a relationship between DWI and ADC with glioma grading in Dr. Soetomo General Academic Hospital patients for the period 2016—2020

Co-Authors Arlia Ayu Damayanti Damayanti, Arlia Ayu Endang Warsiki Endang Warsiki dan Citra Dewi Wahyono Putri (E-Jurnal Agro-Industri Indonesia) Fauzi, Asra Al Haq , Irwan Barlian Immadoel Hari Basuki Hari Basuki Notobroto Heryani, Dini I Gusti Ayu Indah Ardani J Mukono Komang Wahyu Kurniawan Mukono, H J Nur Hidayah Nur Hidayah Pandu Wicaksono Pandu Wicaksono Parenrengi, Muhammad Arifin Puspikawati, Septa Indra Qurratul Aini Qurratul Aini R. Yuvasanghar Ravindra Mohan Ramadhaningtyas , Erica Medina Rohadi Rohadi Sari, Erni A Setiawati, Yunias Sri Andreani Utomo, Sri Andreani Subagio, Eko Agus Suharjono, Suharjono Susilo, Rahadian Indarto Tedy Apriawan Tirthaningsih, Ni Wajan Turchan, Agus Viskasari P. Kalanjati

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