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All Journal Ensiklopedia of Journal Real in Nursing Journal JPK: Jurnal Proteksi Kesehatan Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Journal of Pharmaceutical and Sciences.
Yulia Yesti, Yulia
Laboratorium Kimia Fisika Jurusan Kimia FMIPA-Unand
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UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL BIJI BUAH PARE (Momordica Charantia) PADA MENCIT (Mus Musculus) Devitria, Rosa; Elfia, Mega; Yesti, Yulia; Rafa, Huda Nur
Ensiklopedia of Journal Vol 6, No 2 (2024): Vol. 6 No. 2 Edisi 2 Januari 2024
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v6i2.2139

Abstract

Diabetes Mellitus (DM) is defined as a disease or chronic metabolic disorder with multiple etiologies characterized by high blood sugar levels accompanied by disturbances in carbohydrate, lipid and protein metabolism as a result of insulin insufficiency. The use of traditional medicine in Indonesia is currently in great demand by the public, one type of plant that is widely used as traditional medicine is bitter melon (Momordica charantia). The ingredients of bitter melon which are useful for lowering blood glucose are charantin, insulin polypeptide-P, and lectins. This study aims to determine the antidiabetic activity of the ethanol extract of bitter melon seeds (Momordica charantia) against male mice (Mus musculus) charged with 50% glucose solution. Tests for antidiabetic activity in mice were carried out in 5 treatment groups, namely the negative control group (1% w/v Na-CMC), the positive control group (0.01% Glibenclamide suspension), the first test group (50 mg/kg BW of bitter melon seed extract). , Test Group II (150 mg/kgBB ethanol extract of bitter melon seeds), and Test Group III (250 mg/kgBB ethanol extract of bitter melon seeds). The results of the study were analyzed using the One-Way ANOVA statistical test. The results showed that the ethanol extract of bitter gourd seeds was able to inhibit glucose absorption where the greatest total inhibition occurred at a dose of 250 mg/kg, namely 118 mg/dL, then at a dose of 150 mg/kg, namely 88 mg/dL, and finally at a dose of 50 mg/kg, which is 116 mg/dL.Keywords: Bitter melon fruit seeds (Momordica charantia), antidiabetic, male mice (Mus musculus)
Analisis Kadar Total Fenolik Sediaan Teh Herbal Dari Kulit Buah Naga Super Merah (Selenicereus costaricensis) Dan Daun MINT (Mentha piperita L.) Yesti, Yulia; Fadhilah, Nailatul; Putra, Billy Harnaldo; Elfia, Mega; Devitria, Rosa; Gusriyani, Sri; Saputra, Harry Ade
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 3 No 2 (2024): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v3i2.1526

Abstract

Teh herbal atau herbal tea merupakan salah satu produk minuman campuran teh dan tanaman herbal yang memiliki khasiat dalam membantu pengobatan suatu penyakit atau sebagai penyegar. Teh herbal dapat dikonsumsi sebagai minuman sehat yang praktis untuk menjaga kesehatan. Sampel yang digunakan dalam penelitian ini adalah kulit buah naga super merah (Selenicereus costaricensis) yang diperoleh dari Kecamatan Ampek Angkek, Kabupaten Agam dan daun mint (Mentha piperita L.) yang diperoleh dari Kecamatan Ampek Koto, Kabupaten Agam, Potensi kulit buah naga super merah sebagai obat masih belum termanfaatkan dengan optimal. Salah satu cara untuk mendapatkan khasiatnya, yaitu kulit buah naga super merah (Selenicereus costaricensis) atau super red ini dikonsumsikan dengan daun mint (Mentha piperita L.) dalam bentuk kering yang kemudian diseduh dan diminum. Minuman ini biasanya disebut dengan teh herbal. Tujuan penelitian adalah mengetahui kadar total fenolik terbaik dari 5 variasi komposisi pada sediaan herbal kulit buah naga super merah dan daun mint. Variasi komposisi kulit buah naga super merah dengan daun mint adalah 9:1; 8:2; 7:3; 6:4; 5:5. Uji kadar total fenolik dilakukan menggunakan metoda spektrofotometri UV-Vis. Kadar total fenolik dari 5 variasi komposisi sediaan teh hebal kulit buah naga super merah dan daun mint dengan kadar total fenolik tertinggi pada formulasi 5:5 dengan nilai total kadar fenolik yaitu 0,255 %. Dari hasil penelitian ini dapat disimpulkan bahwa semakin sedikit kulit buah naga super merah dan semakin banyak daun mint maka semakin tinggi kadar total fenolik. Untuk peneliti selanjutnya disarankan menggunakan metoda freeze drying untuk pengeringan agar tidak merusak senyawa yang terdapat dalam sampel.
Preparation And Evaluation Of Hydrogel From Super Red Dragon Fruit Skin Extract (Selenicereus costaricensis) Setiawan, Dwi; Yesti, Yulia; Rahmadasmi, Nola; Fitriani, Oryza Sativa; Andika, Miming; Hasanah, Rizqa; .AH, Ahdi Dinil Haq; Wulandari, Desti; Putri, Nurdina
JURNAL PROTEKSI KESEHATAN Vol 13 No 2 (2024): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v13i2.947

Abstract

Dragon skin is a waste that is rarely used and often discarded. The dragonfruit skin has antioxidant activity related to the anthocyanin content that protects the skin from oxidation damage to prevent premature aging. This study introduces a new approach to utilizing super red dragon fruit skin waste often thrown away, by formulating it into a hydrogel preparation with potential as a cosmetic product. An experimentally used method with a true-experimental design. There are 7 formulas, F1 (base), F2, F3, and F4 (with ultrasonic extract 1%, 2%, 3.). The evaluations included organoleptic tests, homogeneity tests, viscosity testing, pH tests, swelling ratio, freeze and thaw. The results of this study show that super red dragonfruit leather extracts can be formed in hydrogel preparations and have good physical quality properties.
ANALISIS KADAR TOTAL FLAVONOID, ALKALOID SAPONIN, DAN TANNIN EKSTRAK BIJI JAMBU BOL (Syzygium Malaccense L) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Devitria, Rosa; Elfia, Mega; Yesti, Yulia; Astuti Sari, Winda
Ensiklopedia of Journal Vol 7, No 2 (2025): Vol. 7 No. 2 Edisi 1 Januari 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i2.2792

Abstract

Indonesia is one of the world's island nations with high biodiversity of flora and fauna. The country's strategic geographical position is one of the factors contributing to its rich biodiversity. The global agreements on the disclosure and sustainable utilization of biodiversity for human needs are increasingly prevalent. Guava is rich in fiber, calcium, phosphorus, vitamin A, thiamine, riboflavin, ascorbic acid, and niacin. Although there is no medical research yet, Guava is believed to help alleviate constipation, diabetes, cough, headaches, and inflammation of the respiratory mucosa. Meanwhile, its seeds, bark, and leaves possess dynamic properties and have effects on blood pressure and respiration. To determine the properties of compounds contained in guava seed extract. This research uses quantitative and qualitative methods. The results of this research show that guava seeds have total flavonoid levels of 1.4008%, saponins 9.3363%, tannins 1.2703%, and alkaloids 1.8490%. The conclusion is that guava seeds contain positive secondary metabolite compounds including flavonoids, alkaloids, tannins and saponins. Keywords: Guava seeds, secondary metabolite compounds
Pengaruh Pemberian Kompres Bubuk Jahe Merah Terhadap Nyeri Pada Lansia Dengan Gout Arthtritis Putri, Ghea Indah; Rahmiwati, Rahmiwati; Yesti, Yulia
REAL in Nursing Journal Vol 4, No 1 (2021): REAL in Nursing Journal
Publisher : Universitas Fort De Kock Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/rnj.v4i1.1190

Abstract

Background: Gout was once called the king of disease and disease of king. Ordinary people call it gout. Gout is a metabolic disease caused by excess levels of uric compounds in the body, either due to overproduction, inadequate elimination, or increased purine intake. This study aims to determine the effect of giving red ginger powder compresses to pain in the elderly with gout arthritis. Methods: This study used the Quasy Experiment design with the design used was the pretest-posttest control group design. Results: The results showed that there was a significant effect of giving red ginger powder on pain in the elderly with Gout Arthritis (p-value = 0.000). The Respondents 'Pain Scale Before Giving Ginger Powder Compress with a mean = 4.20 and there was a decrease in the Respondents' Pain Scale after Ginger Powder Compress was given with a mean = 2.30. Conclusion: It can be concluded that the administration of red ginger powder compresses can reduce pain in the elderly. Therefore, it is advisable for gout arthritic patients to take advantage of red ginger powder compresses as an effort to control gout arthritis.Keywords: Pain, Gout Arthritis, Red ginger powder compress, Elderly
PENAMBAHAN TEPUNG KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) SEBAGAI SUMBER ANTIOKSIDAN PADA MAKANAN SEREAL Fatma, Fatma; Devitria, Rosa; Putri, Rahayu Nadia; Elfia, Mega; Yesti, Yulia
Ensiklopedia of Journal Vol 7, No 4 (2025): Vol. 7 No. 4 Edisi 1 Juli 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i4.3212

Abstract

Dragon fruit is one of the plants that has a high antioxidant content. Consumption of red dragon fruit only utilizes the fruit, while the skin waste which amounts to 30-35% of the fruit weight is underutilized. This study aims to determine whether the addition of red dragon fruit peel flour in cereal foods can increase antioxidant content using the DPPH (2,2-diphenyl-1-1-picrylhydrazyl) method. The inhibition power against oxidation through the antioxidant content test of red dragon fruit peel flour is 50.84%, and the inhibition power against oxidation obtained through the antioxidant content test of red dragon fruit peel flour and cereal is 25.83%. The sensory test results conducted on the taste test of 20 untrained panelists proved that the red dragon fruit peel flour could be well received by the panelists. The antioxidant inhibition level which is not too high with a value of 51% provides an opportunity for red dragon fruit peel as a natural antioxidant ingredient in food. The test results of the addition of red dragon fruit peel flour still have potential as a food additive that contains antioxidants and can be well received by people. Keywords: Dragon Fruit, Antioxidants, Cereals
Uji Aktivitas Antibakteri Fraksi Etanol Daun Kelor (Moringa oleifera L.) Terhadap Staphylococcus aureus dan Staphylococcus epidermidis Dewi, Asiska Permata; Darmadi, Darmadi; Yesti, Yulia
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.393

Abstract

Moringa olifera L. is a herbaceous plant that consists of phytochemicals such as flavonoids, saponins cytokinins, acid-caffeoylquinic and contains unsaturated fatty acids such as linoleic (omega 6) and alfalinolenat (omega 3). This research aimed to determine the chemical compound content in the ethanol fraction of Moringa leaves and test its antibacterial activity against Staphylococcus aureus and Staphylococcus epidermidis. Phytochemical screening was carried out through a color reaction using a certain reagent; then the antibacterial activity test was carried out using the disc diffusion method with ethanol fraction concentrations of 15%, 30%, 45%, and 60%. The results showed that the compounds contained in the ethanol fraction of Moringa leaves were alkaloid, flavonoid, saponin, and tannin. The diameter of the inhibition zone for S. aureus bacteria is 7.43 mm – 10.16 mm, while for S. epidermidis bacteria is in the range 7.43 mm – 10.48 mm. It can be concluded that the ethanol fraction of Moringa leaves has antibacterial activity against S. aureus and S. epidermidis bacteria.
Co-Authors .AH, Ahdi Dinil Haq Asiska Permata Dewi Astuti Sari, Winda Billy Harnaldo Putra, Dini Fatmi, Darmadi Darmadi Dwi Setiawan Fatma Fitriani, Oryza Sativa Gusriyani, Sri Harry Ade Saputra Mega Elfia Miming Andika Nailatul Fadhilah Nurdina Putri Putri, Ghea Indah Putri, Rahayu Nadia Rafa, Huda Nur Rahmadasmi, Nola Rahmiwati Rahmiwati, Rahmiwati Rizqa Hasanah Rosa Devitria Wulandari, Desti