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Wahyu Ramadhan
Fakultas Kedokteran Universitas Abdurrab, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Lunasin's Mechanism as an Antioxidant and Hypocholesterolemic Agent Santi Widiasari; Sabrina Hayati; May Valzon; Wahyu Ramadhan
International Journal Of Health Science Vol. 5 No. 1 (2025): : International Journal of Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v5i1.5637

Abstract

Several ways that can help lower cholesterol levels in the blood include using drugs (pharmacotherapy) or by modifying lifestyle and consuming certain foods. One of them is lunasin. Lunasin is a peptide found in soybean plants and is a promising drug candidate because it has broad health effects such as antioxidant, anti-inflammatory, anti-cancer, and lowering blood cholesterol through various mechanisms. This paper aims to examine the role and mechanism of action of lunasin as an antioxidant and its ability to lower blood cholesterol levels due to the unique peptide structure of lunasin as well as the bioavailability of lunasin starting from degradation, absorption, translocation and distribution of lunasin to target organs or target tissues after oral administration . This paper also discusses soybean plants as the main source of lunasin and the optimal content of lunasin in soybeans.
Co-Authors Agung Ramadhan Alfin Surya Ari Diansyah Brilian Dini Ma. Iballa Deri Islami Dewi Sartika Siagian Dinda Queenty Dzakiyah Hartono Elly Anggreny Fenny Anita Islami, Deri M. Naufal Makarim Ma Iballa, Brilian Dini Marwan, Deinike Wanita Nengsi Fitria Nurjamilah Nurjamilah Pratiwi, Yuharika Reiza Mutia Riki Richer Sabrina Hayati Santi Widiasari Siregar, Elan Dehardiyanti Siti Juariah Siti Juariah Sukri Sukri Valzon, May Wahyu Margi Sidoretno Yan Hendrika