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Journal : Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan

Pola Penggunaan Antibiotik Pada Pasien Pneumonia Dewasa Rawat Inap RSU PKU Muhammadiyah Bantul Periode Tahun 2022 Mithasari Hutami; Hanita Christiandari; Jarot Yogi Hernawan
An-Najat Vol. 2 No. 1 (2024): FEBRUARI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i1.663

Abstract

The prevalence of pneumoniae deaths in the world is around 2.56 million people in 2017. Based on the 2018 Riskesdas data, in Indonesia there has been an increase in the prevalence of pneumonia at all ages from 1.6% (2013) to 2.0% (2018). Pneumonia is an inflammation of the lungs that causes pain when breathing and limits oxygen intake. Pneumonia is caused by bacteria, viruses or mycoplasma. Antibiotics are the main drug in the management of infectious diseases. Adult patients are the groups most at risk for pneumoniae. Purpose: Knowing the pattern of antibiotic use in hospitalized adult pneumonia patients at RSU PKU Muhammadiyah Bantul for the 2022 period. This research is a non-experimental descriptive study. The sample used was 170 patients. Recording of patient data includes the patient's RM number, gender, age, drug given. Data were processed and analyzed descriptively, then calculated in percentage form and presented in tabular form. Results the research it showed the results of patients with an inpatient diagnosis of pneumonia dominated by men 59% and the elderly group 65%. The most widely used class of antibiotics were cephalosporin 36.65%, macrolide 33.22% and quinolones 22.95%. The most widely used antibiotic names were azithromycin 33.22%, ceftriaxone 23.63%, and levofloxacin 19.18%. The most common route of administration of antibiotics was the parenteral route 83% and the oral route 17% with the longest duration of administration of antibiotics for 3 days 47%, 5 days 36%, 7 days 12%, and 5% for administration of antibiotics > 7 days. Conclusion: Patients diagnosed with adult pneumoniae were dominated by 59% of men and 65% of the elderly group. The most widely used class of antibiotics was cephalosporins at 36.65%. The most widely used parenteral antibiotic was azithromycin at 33.22% with the longest duration of antibiotics being 3 days at 47%.
Formulasi Sediaan Serum Antioksidan dari Ekstrak Sari Tomat (Solanum Lycopersicum L.) sebagai Perawatan Kulit Hanita Christiandari; Intan Kumalawati; Jarot Yogi Hernawan
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3185

Abstract

Skin damage occurs because free radicals lose one electron in their outer orbit so that they are highly reactive which can cause oxidative stress. The impact is damage to body cells, such as large pores, acne, wrinkles and dark spots. Free radicals can come from the metebolism process in the body and from outside the body. One preparation that can prevent skin damage is a serum that contains antioxidants. To determine the physical properties, namely organoleptics, homogeneity, pH, spreadability, and adhesiveness of tomato juice extract (Solanum lycopersicum L.) serum preparations. The type of research used is experimental. The sample used was tomato juice extract. The research was conducted at the Pharmacy Laboratory of Politeknik Permata Indonesia Yogyakarta in May-June 2024. The independent variables of this study were 2%, 4%, 6% tomato juice extract. The dependent variable in this study is the test of physical properties of serum preparations including organoleptical tests, homogeneity, pH, spreadability, and adhesiveness. Data analysis in this method uses One way ANOVA. Organoleptical results are viscous, clear, clear yellow, light brown to dark brown in color and smells rose. The homogeneity results of the three formulations are homogeneous. The pH value in F0 was 5.08; F1 was 5.20; F2 was 5.35; F3 was 5.51. The value of spreadability in F0 was 5.2cm; F1 was 5.78cm; F2 was 5.91cm; F3 was 6.23cm. The stickiness value in F0 was 8.82; F1 was 15.94; F2 was 23.11; F3 was 30.75. All formulas have organoleptical arrangement, homogeneity, pH, spreadability, and adhesiveness that meet the requirements. Serum preparation of tomato juice extract (Solanum lycopersicum L.) has eligible physical properties.