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All Journal Pharmaciana: Jurnal Kefarmasian Berkala Kedokteran JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) CRJIM (Clinical and Research Journal in Internal Medicine) Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
Azma Rosida, Azma
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Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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HUBUNGAN ASUPAN ZAT BESI DENGAN KEJADIAN ANEMIA PADA REMAJA PUTRI DI SMP NEGERI 12 BANJARMASIN Aryani, Siti Raihanah; Noor, Meitria Syahadatina; Rosida, Azma; Heriyani, Farida; Muthmainah, Noor
Homeostasis Vol 7, No 3 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i3.14599

Abstract

Abstract: According to 2018 Riskesdas results, the prevalence of anemia in adolescents is 32%. Anemia in adolescent girls generally occurs due to a lack of food intake containing good nutrition, namely iron, resulting in low red blood cell production. The study aims to examine the relationship between iron consumption and the incidence of anemia among adolescent girls students at Junior High School 12 Banjarmasin. Using analytical observational methods with a cross sectional approach. The research sample included 90. The results showed that 57 respondents had Hb levels <12gr/dL and 33 respondents had Hb levels >12gr/dL (36.7%), iron intake met the daily adequacy figure of 25.5% and 74.5% was less. The results of the chi square test analysis show a p value = 0.234. Therefore, it can be concluded that there is no relationship between iron intake and the incidence of anemia in young women at Junior High School 12 Banjarmasin. Keywords: iron intake, anemia, adolescent girls Abstrak: Menurut data Riskesdas tahun 2018 angka prevalensi anemia remaja sebesar 32%. Anemia pada remaja putri umumnya terjadi karena kurangnya asupan makanan gizi baik yaitu zat besi mengakibatkan produksi sel darah merah yang sedikit. Tujuan penelitian untuk mengetahui apakah terdapat hubungan antara konsumsi zat besi dengan kejadian anemia pada remaja putri di SMP Negeri 12 Banjarmasin. Menggunakan metode observasional analitik dengan pendekatan cross sectional. Sampel penelitian remaja putri SMP Negeri 12 Banjarmasin dengan jumlah 90 orang. Hasil penelitian menunjukkan 57 responden memiliki kadar Hb <12gr/dL dan 33 responden menunjukkan kadar Hb >12gr/dL (36,7%), asupan zat besi memenuhi angka kecukupan harian sebesar 25,5% dan kurang 74,5%. Hasil analisis uji chi square menunjukkan nilai p = 0,234. Sehingga dapat disimpulkan tidak ada hubungan antara asupan zat besi dengan kejadian anemia pada remaja putri di SMP Negeri 12 Banjarmasin. Kata-kata kunci: Asupan zat besi, anemia, remaja putri
Acute oral toxicity test and determination of lethal dose (LD50) of Garcinia forbesii King leaf extract in wistar rats Rudiansyah, Mohammad; Rosida, Azma; Kania, Nia; Devi, Wivina Riza; Nirmalasari, Nila
Pharmaciana Vol. 15 No. 1 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i1.29616

Abstract

Garcinia forbesii King, an endemic plant from Sumatra and Kalimantan, is traditionally used for treating skin infections and inflammation. Its potential use as a raw material for medicines needs to be supported by safety tests. The purpose of this study is to assess the acute toxicity of its 70% leaf extract in male Wistar rats, evaluating clinical symptoms, body weight changes, organ indices, and the lethal dose (LD50). The study administered extract doses orally at 5 (G2), 50 (G3), 300 (G4), and 2,000 (G5) mg/kg BW, monitoring toxicity signs over 14 days. Symptoms such as piloerection, respiratory distress, and soft feces were noted. Significant weight loss was observed at doses of 2,000 mg/kg BW. There was no significant effect on the kidney index, but the liver and heart indices exhibited significantly lower changes compared to the control. The LD50 value was estimated to be between 2,000-5,000 mg/kg BW. Further studies are recommended to assess histopathological effects and identify harmful chemicals in the plant.
Co-Authors Abimanyu, Bambang Adenan Adenan, Adenan Agung Ary Wibowo, Agung Ary Aryani, Siti Raihanah Asie, Gracia Chika Medylona Eka Atikah Rahayu Devi, Wivina Riza Dharagita, Putu Galuh Fahrini Yulidasari Farida Heriyani Ferry Armanza, Ferry FX Hendriyono Hendriyono, Franciscus Xaverius Hendriyono, Fransiskus Xaverius Ida Yuliana Ihya Ridlo Nizomy, Ihya Ridlo Iman, Muhammad Nur Kholifah, Rika Kireyna, Ervia Manik, Sarmono Lotma Saipon Meitria Syahadatina Noor Mohammad Rudiansyah Muthmainah, Noor Nanang Miftah Fajari Nia Kania Nila Nirmalasari, Nila Renny Ismaya, Renny Taufiq Hidayat Winata, Winardi Budi Yuseran, Hariadi