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All Journal Jurnal Kesehatan Bina Generasi Diagnosis: Jurnal Ilmiah Kesehatan Jurnal Berita Kesehatan AACENDIKIA: Journal of Nursing Women Midwives and Midwifery Mega Buana Journal of Innovation and Community Service (JICS) Jurnal Kedokteran Meditek Jurnal Pengabdian Kepada Masyarakat Pusat Unggulan Iptek Penanggulangan Stunting Berbasis Kesehatan Ibu dan Anak
Dewi Hastuty
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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The Relationship Between Socio-Economic and Cultural Status and Teenage Marriage in The Work Area Of Campalagian Community Health Center In 2024 Jamir, A.Fatimah; Lina Fitriani; Yanti, Yuniar Dwi; Hastuty, Dewi
Women, Midwives and Midwifery Vol. 5 No. 3 (2025): Women, Midwives and Midwifery journal
Publisher : Asosiasi Pendidikan Kebidanan Indonesia (AIPKIND)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36749/wmm.5.3.1-10.2025

Abstract

Marriage is a physical and spiritual bond between a man and a woman to build a life together, fostering a family. West Sulawesi Province is the region with the highest rate of early marriage in Indonesia. According to the 2020 National Social and National Survey (SUSENAS) data, the rate of early marriage in West Sulawesi reached 10.05 percent. These figures demonstrate that early marriage remains prevalent in Indonesia. Purpose: This study aims to examine the relationship between socioeconomic and cultural factors and adolescent marriage in the working area of the Campalagian Health Center. Methods: An analytic survey with a cross-sectional design was used in this study, conducted in 2024. The population consisted of women of childbearing age (WUS) aged 15–25 years. A total of 87 participants were selected using purposive sampling and the Slovin formula. Data were collected through structured questionnaires and analyzed using the chi-square test with the assistance of SPSS software. Results: The findings showed a significant relationship between socioeconomic status and adolescent marriage (p = 0.000 < 0.05), and between cultural values and adolescent marriage (p = 0.000 < 0.05). Among respondents who married before the age of 20, most had lower socioeconomic backgrounds or were influenced by traditions such as early arranged marriages. Conclusion: There is a significant association between socioeconomic and cultural factors and adolescent marriage in the Campalagian Health Center area. The study recommends that the government strengthen education and advocacy programs to reduce early marriage practices and raise awareness of its long-term health and social impacts.
Analysis of D-Dimer Levels Based on Histopathological Grading of Breast Cancer Devita, Yessi; Digambiro, Reza Aditya; Hastuty, Dewi
Jurnal Kedokteran Meditek Vol 31 No 6 (2025): November
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i6.3974

Abstract

Background: Breast cancer is the most common malignancy among women worldwide. Systemic activation of coagulation, reflected by elevated D-dimer levels, has been associated with advanced stage, metastasis, and poor prognosis in breast cancer. However, it remains unclear whether D-dimer also correlates with histopathological grade as an indicator of intrinsic tumor aggressiveness, particularly among patients with invasive breast cancer in Indonesia. Objective: To evaluate the association between plasma D-dimer levels and histopathological grading of invasive breast cancer. Methods: This cross-sectional study included 180 untreated female patients with primary invasive breast cancer, comprising 60 cases each of Grade I, Grade II, and Grade III tumors. Plasma D-dimer levels were measured using a latex-enhanced immunoturbidimetric assay, and histological grading was determined according to the Nottingham system. Data were analyzed using the Kruskal–Wallis test, ANOVA on log-transformed values, post-hoc tests, and ANCOVA with adjustment for age, body mass index (BMI), clinical stage, C-reactive protein (CRP), lymphovascular invasion, and molecular subtype. Receiver operating characteristic (ROC) analysis was performed to distinguish Grade III from lower grades. Results: Median D-dimer levels increased progressively from Grade I (501.7 ng/mL) to Grade II (831.0 ng/mL) and Grade III (1312.9 ng/mL), with a statistically significant overall difference (p < 0.001). ROC analysis for identifying Grade III yielded an AUC of 0.960 with an optimal cut-off of 965.5 ng/mL FEU (sensitivity 91.7%, specificity 90.0%). Conclusion: Plasma D-dimer levels are significantly associated with histopathological grade in invasive breast cancer, independent of potential confounders. These findings suggest that D-dimer testing may help identify patients with high-grade tumors at an early stage, thereby refining risk stratification, informing more intensive treatment planning, and raising vigilance for thromboembolic complications, particularly in resource-limited settings.. ctice.
Co-Authors Adeliana Adeliana, Adeliana Akhfar, Kurniati Amiruddin, Asri Angka, Andi Tenri Arfianty, Yenny Arfinati, Yenny Arianto Dangkeng Arnianti Arnianti Arnianti Devita, Yessi Dwi Yanti, Yuniar Eka Fitriyani, Eka Eka Sari, Erni Fadli , Fadli Fadli Fadli Fitriani, lina Hamid, Hasnaini Hardiansyah Hardiansyah Husnul Khatimah Husri, Hasiwulansi Indah Pertiwi, Aulia Jamir, A.Fatimah kasma, kasmayani kasmayani Lina Fitriani lisa magfirah Mangallo, Agus Nurhikma, Nurhikma Olivia Olivia Rahma, Rahmaniar Reza Aditya Digambiro Rosalinda, Sherly Rosita Rosita Sarikasih, Wayan Solihin, rachmawati Suhaib, Elma Suwandi N Tahir, Dyah Umami, Nurrahmi Yenni Yuris Yuris, Yuris