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Analisis Rasionalitas Penggunaan Antiplatelet Aspirin Dan Clopidrogel Sebagai Monoterapi Pada Pasien Stroke Iskemik Ridho Dwi Muktiono; Khamdiyah Indah Kurniasih; Silma Kaaffah
CERATA Jurnal Ilmu Farmasi Vol 16 No 2 (2025): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v16i2.2053

Abstract

Stroke termasuk faktor utama disabilitas dan kematian nomor dua di dunia. Antiplatelet yaitu pengobatan untuk stroke iskemik dilakukan dengan memberi obat anti-agregasi platelet yang bertujuan untuk menghambat penggumpalan trombosit, sehingga mencegah terbentuknya trombus yang sering terjadi pada sistem arteri. Aspirin dan clopidogrel termasuk agen antiplatelet yang direkomendasikan oleh kementerian kesehatan melalui Pedoman Nasional Pelayanan Kedokteran Tata Laksana Stroke Tahun 2019. Tujuan penelitian ini supaya tahu rasionalitas pemakaian antiplatelet aspirin dan clopidrogel sebagai monoterapi pada pasien Rawat inap stroke iskemik di RSUD Prof. Dr. Margono Soekarjo. Penelitian ini yakni deskriptif kuantitatif dengan pendekatan secara retsrospektif dengan memakai data sekunder yaitu rekam medis pasien di RSUD Prof. Dr. Margono. Hasil penelitian dari total 100 pasien stroke iskemik mayoritas laki laki banyaknya 60 pasien (60%) dan wanita banyaknya 40 pasien (40%). Usia pasien mayoritas 56 – 65 tahun banyaknya 41 pasien (41%). Pemakaian obat antiplatelet yang paling banyak dipakai yaitu clopidogrel banyaknya 83%. Evaluasi rasionalitas sesuai tepat pasien 100%, tepat obat 83%, tepat dosis 100%, dan tepat interval 100%.
The Pengaruh Penyuluhan Kesehatan Penanganan Scabies (Sarcoptes Scabiei) Terhadap Tingkat Pengetahuan Swamedikasi Santri Pondok Pesantren Darussalam : Pengaruh Penyuluhan Kesehatan Penanganan Scabies (Sarcoptes Scabiei) Terhadap Tingkat Pengetahuan Swamedikasi Santri Pondok Pesantren Darussalam RADIAHAYYA, NABILA; FAUZIAH; SILMA KAAFFAH
Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i2.822

Abstract

Scabies is a skin disease caused by the Sarcoptes scabiei mite, and is often suffered by individuals who live in groups such as dormitories, Islamic boarding schools, densely populated housing. Knowledge plays an important role in handling the transmission of scabies by practicing personal hygiene or by self-medication. This study aims to determine the level of knowledge of sel-medication in handling scabies in student at Islamic Boarding School in Purwokerto. The study was conduxted using a uestionnaire that had been tasted for validity and reliability through a one group pre-post design approach, which was conducted in march 2024 using a systematic random sampling technique and a sample of 55 students was obtained. Based on the results of the Cronbach alpha reliability test were reliable. The results of the univariate analysis showed that the majority of respondents were aged 15-20 years and female. The results of the bivariate anaysis of the Wilcoxon test showed that the level of khowledge of students before and after the intervention increased significantly (p-value < 0.05), namely from the good category of 61.8% to 89.1% and the sufficient category from 38.2% to 10.9%. in conclusion, periodic education is needed to provide information to student so that students’ knowledge increases further. Keywords : level of khowledge, scabies, pre-post, questionnaire, systematic random sampling
Determinants of Medication Adherence in Hypertension Patients in Level I Health Facilities in Kembaran District Silma Kaaffah; Galih Samodra; Yulinda Eka Pratiwi
Viva Medika Vol 17 No 2 (2024)
Publisher : LPPM Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i2.1399

Abstract

Medication adherence is the key to controlling blood pressure in hypertensive patients to minimize the risk of complications. The research aims to assess level of medication adherence and identify influencing factors. The quasi-experimental research method used purposive sampling to create a control group and 2 intervention groups (pill box and medication chart) with each group 30 patients. Prospective data collection with pre-post design (week-1 and week-4) as well as observing clinical data on blood pressure, medication adherence. Questionnaire of medication non-adherence determinants was taken at week 4. The questionnaire instrument was validated with Cronbach Alpha reliability >0.06. The results of the statistical analysis were significant (p-value <0.05) with increasing the mean score of medication adherence in the pill box was 1.2 and the medication chart was 0.7. The reduction in systolic blood pressure in the intervention group was significant (p-value <0.05) by more than 2 mmHg. A total of 35.6% of patients were reluctant to ask health workers for medication information and 45.6% needed someone to remind them to take medication. In conclusion, increasing medication adherence and reducing blood pressure can be achieved with intervention and requires social support from family and health-care professional.
The Relationship Between Adherence to Taking Medication with the Level of Knowledge and Family Support in TB Patients at Kroya Health Centre, Cilacap Regency Hidayat Sugeng Riyadi; Fauziah; Silma Kaaffah
Viva Medika Vol 17 No 3 (2024)
Publisher : LPPM Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i3.1604

Abstract

TB (Tuberculosis) patients in Indonesia are the 2nd highest in the world after India. The large number of TB patients in Indonesia is due to the lack of success in TB treatment due to patient non-compliance with medication regularly. Factors that affect non-compliance are low knowledge of TB patients and lack of family support. This study aims to determine the level of family knowledge and support, medication adherence, and determine the relationship between the level of knowledge and family support to medication adherence in TB patients at the Kroya Health Center, Cilacap Regency in 2024. This study uses a non-experimental method with cross-sectional data collection conducted in April-May 2024. The study population is all TB patients totaling 130 respondents who underwent treatment at the Kroya Health Center, Cilacap Regency from November 2023 to May 2024, and the research sample was 56 respondents. The conclusion of this study is that the knowledge level of TB respondents is the highest at 37.5% and 55.4%, and the adherence to taking medication at the Kroya Health Center is 30.4% and 57.1%. In this study, the highest TB patients were at a moderate level of knowledge (55.4%); family support is not supportive (96.4%) and medication adherence is low (30.4%) to moderate (57.1%). Testing with the chi-square method there was a relationship between the level of knowledge and medication adherence in TB patients (p-value 0.000), but there was no relationship between family support and medication adherence (p-value 0.268) in patients at the Kroya Health Center, Cilacap Regency with a r value of 0.541. The limitation of this study is that there is no follow-up on the respondents such as monitoring TB drugs so that the existing data is only data taken when filling out the questionnaire.