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All Journal Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Respirasi (JR) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia World Nutrition Journal Archives of The Medicine and Case Reports Tarumanagara Medical Journal Eduvest - Journal of Universal Studies
Krisadelfa Sutanto
Department Of Nutritional Sciences, Faculty Of Medicine, University Of Indonesia – Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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External validation test of body height estimation on outpatient radiotherapy clinic of Dr. Cipto Mangunkusumo General Hospital Wiji Lestari; Fiastuti Witjaksono; Nurul Ratna Mutu Manikam; Wahyu Ika Wardhani; Krisadelfa Sutanto
World Nutrition Journal Vol. 6 No. 2 (2023): Volume 06 Issue 2, February 2023
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.i2.0007

Abstract

Background : Stature is required to calculate body mass index and determine the energy needs of patients in nutritional medical therapy. Difficulty was found to obtain stature data in patients who are unable to stand. Therefore, there are some height estimation formula to predict the actual height using knee height. This study aimed to validate the Chumlea formula on outpatient clinic of Dr. Cipto Mangunkusumo General Hospital, Indonesia. Methods : This cross-sectional study used 90 respondents selected by consecutive sampling. Actual height, knee height, age and gender data were collected. Estimated height using the three of Chumlea formula. Pearson correlation was used to see the correlation between actual height and estimated height. Paired t-test were used to determine the difference significance. Results : The average age of the subjects was 45±10 years old with actual height 157±10 cm, and knee height 48.8±3.5 cm. A strong positive correlation was found between actual height with all estimated height on male (p=0.000; r > 0.8) and female subjects (p=0.000; r > 0.6). However, comparison between actual height and estimated height showed no significant differences only in Chumlea L1 formula (p=0.087) and Chumlea L3 formula (p=0.824) on the male subjects. Conclusions : Chumlea L1 and Chumlea L3 formula was a valid fomulation for calculating the estimated body height in adult male patients. There was no valid Chumlea’s formulation to estimate body height in female patients.
Metabolic effects of monounsaturated fatty acid−enriched diets on glycaemic control in patient with type 2 diabetes: an evidence-based case report Krisadelfa Sutanto; Diana Sunardi; arieska felicia
World Nutrition Journal Vol. 6 No. 2 (2023): Volume 06 Issue 2, February 2023
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.i2.0005

Abstract

Introduction: Diabetes mellitus type 2 (T2D) is the most common type of diabetes. There is an ongoing debate as to whether nutrient quality or quantity is mainly responsible for the effects on hyperglycaemic control of patients with T2D. Monounsaturated fatty acid (MUFA) has a metabolic effect in reducing the risk factor for metabolic syndrome to prevent and control hyperglycaemia in patients with T2D and is recommended by professional organizations. Methods: Literature searching was conducted by advanced searching in Pubmed, Cochrane Library, Scopus, and ProQuest database using MeSH Terms combined with Title/Abstract. After removing duplicates, the literature were screened based on the eligibility criteria. Critical appraisal and level of evidence of the selected literature were determined based on Oxford Centre for Evidence-Based Medicine. Results: Two selected literature were relevant to answer our clinical question, both literature are systematic review/meta-analysis studies. The first literature is a study by Fumiaki et al. (2016), while the second is by Frank Qian et al. (2016). All literature provided evidence that a diet high in MUFA could improve glucose-insulin homeostasis among patients with T2D. These effects were marked by lower fasting blood glucose and haemoglobin A1c (HbA1c), and insulin level in the enriched MUFA diet group compared to PUFA. Conclusion: Nutrient quality is mainly responsible for the effects on glycaemic control profile in patients with T2D, with a high MUFA diet consistent with favourable effects to improve fasting glucose and HbA1c.
Effect of smartphone application with reminder on total fluid intake adequacy and hydration status among adults in Bontang, East Kalimantan Handayani Eka Puspita Sari; Diana Sunardi; Krisadelfa Sutanto; Dian Novita Chandra; Dewi Friska; Putri Novia Choiri Insani
World Nutrition Journal Vol. 7 No. 2 (2024): WNJ. Volume 07 Issue 2, February 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V07.i2.0007

Abstract

Background: About 41% adults in Kalimantan have inadequate total fluid intake (TFI), which is higher than national inadequacy (28%). Inadequate TFI may cause dehydration. The biggest barrier to comply with TFI is to forget to drink. Smartphone application, Hidrasiku with reminder, is expected to be useful in TFI adequacy which may affect hydration status. Objective: This study aims to determine the effect of the Hidrasiku with reminder on the TFI adequacy and hydration status among adults in Bontang. Methods: The design of this study was quasi-experimental and cluster sampling. Inclusion criteria were healthy men, age 19-64 years and having a smartphone. Participants suffering with diseases that affected fluid balance and on diet and fluid restriction were excluded. Data collection was conducted from April to June 2023 in Bontang. A total of 106 participants were allocated into two groups, intervention and control. Both groups used Hidrasiku for four weeks, with the intervention group activating the reminder while the control group didn’t. Adequacy of TFI and hydration status were assessed before-after intervention. Results: A sample of 87 participants completed the study. The median age of the participants was 32 (19-61) years. At the end of intervention, there was significant difference in the TFI adequacy (90.2% vs 63.0%; p=0.003) and a significant increase in TFI +240 mL/day vs – 62.8 mL/day; p=0.002). Meanwhile no significant difference on hydration status (87.8% vs 73.9%; p=0.103). Conclusions: Hidrasiku with reminder has effect on the TFI adequacy and no effect on hydration status
The Role of Branched-Chain Amino Acids and Eicosapentaenoic Acid in Improving Body Composition and Functional Capacity in Nasopharyngeal Carcinoma Patients with Cancer Cachexia: A Case Report K.N, Beta Novianti; Krisadelfa Sutanto; Nurul Ratna Mutu Manikam
Archives of The Medicine and Case Reports Vol. 5 No. 3 (2024): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v5i3.596

Abstract

Introduction: Cancer cachexia is a debilitating syndrome characterized by involuntary weight loss, muscle wasting, and functional decline, negatively impacting quality of life and survival. Nutritional interventions, including branched-chain amino acids (BCAAs) and eicosapentaenoic acid (EPA), have shown promise in ameliorating cachexia. This case report illustrates the potential benefits of these nutrients in a patient with nasopharyngeal carcinoma. Case presentation: A 65-year-old female presented with severe fatigue, dysphagia, and significant weight loss (11 kg in 6 months) secondary to nasopharyngeal carcinoma (T1N3Mx, stage IV). She was diagnosed with cancer cachexia and severe malnutrition. Nutritional therapy included enteral nutrition with 1.5-2 g/kgBW/day protein, 11-12 g/day BCAAs, and 1-2 g/day EPA. Conclusion: This case report suggests that a nutritional approach combining high protein, BCAAs, and EPA may improve body composition and functional capacity in patients with cancer cachexia. Further research is warranted to confirm these findings in larger studies.
Effect of probiotic administration in adult atopic dermatitis patients: An evidence-based case report Paramita, Dewita Nina Paramita; Sutanto, Krisadelfa
World Nutrition Journal Vol. 8 No. 1 (2024): WNJ. Volume 08 Issue 1, August 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i1.0006

Abstract

Introduction: Atopic dermatitis (AD) is a chronic skin disease characterized by abnormal skin barrier function and heightened immunologic sensitization. Its incidence has surged recently, with approximately 60% of cases diagnosed within the first year of life. AD can persist or recur, significantly deteriorating the quality of life due to persistent itching and sleep disturbances. Individuals with AD are at increased risk of developing other atopic disorders like asthma and allergic rhinitis. Various dietary approaches, including low carbohydrate, calorie, and fat diets, have been associated with enhanced quality of life by regulating immune responses. Probiotics have been used as adjuvant therapy in allergic conditions, though their effectiveness varies due to the complex nature of allergies. Method: A literature search was conducted using PubMed, Cochrane Library, and Google Scholar. MeSH terms, advanced search strategies, and predefined eligibility criteria were employed to identify relevant studies. Duplicate studies were excluded, and critical assessment tools and levels of evidence were defined per Oxford Center for Evidence-based Medicine standards. Results: One systematic review and meta-analysis of randomized controlled trials (RCTs) met the PICO and eligibility criteria. The meta-analysis demonstrated that probiotics significantly decreased AD severity in adults, enhancing their overall quality of life. Other meta-analyses and systematic reviews supported that probiotics reduce clinical severity and improve life quality in adult AD patients. Conclusion: Probiotic supplementation is a viable option to improve the quality of life for adult AD patients, offering potential therapeutic benefits in managing this condition.
Correlation of calorie intake with 24-hour urinary urea nitrogen level changes in critically ill patients at RSUI Depok, Indonesia Githa Putri Puspita Sari; Witjaksono, Fiastuti; Sutanto, Krisadelfa; Singal, Anna Maurina
World Nutrition Journal Vol. 8 No. S1 (2024): Selected conference proceedings of the Nutri Symposium 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.S1.0041

Abstract

Calorie together with protein intake has been proven to be important factors that play a role in critically ill patients. Hypermetabolism in the early acute phase increases energy expenditure and calorie requirement. Insufficient calorie intake will increase protein degradation for gluconeogenesis, which can be assessed by the level of 24-hour urinary urea nitrogen (UUN). Adequate daily calorie intake is expected to improve the UUN level in patients. This study aims to investigates the correlation of calorie intake with UUN level changes in critically ill patients.
Pengaruh suplementasi vitamin D terhadap peningkatan berat badan pada pasien tuberkulosis paru: Tinjauan literatur Wulandari, Dewi; Sutanto, Krisadelfa
Tarumanagara Medical Journal Vol. 7 No. 1 (2025): TARUMANAGARA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/tmj.v7i1.34097

Abstract

Tuberkulosis (TB) merupakan penyebab kematian kedua tertinggi di dunia akibat satu agen infeksi. Pasien TB sering mengalami malnutrisi dan kekurangan mikronutrien, termasuk vitamin D. Vitamin D berperan sebagai imunomodulator dalam melindungi tubuh terhadap infeksi. Studi ini bertujuan mengevaluasi penggunaan suplementasi vitamin D sebagai terapi tambahan pada pasien TB aktif dan dampaknya terhadap status gizi, yang dinilai melalui parameter kenaikan berat badan. Studi dilakukan melalui pencarian literatur dengan menggunakan tiga basis data utama, yaitu PubMed, Cochrane, dan Google Scholar dengan menyesuaikan kriteria inklusi yang telah ditentukan. Tahun publikasi artikel yang diikutsertakan antara tahun 2019 hingga 2024. Metode penilaian kritis terhadap studi yang terpilih menggunakan pendekatan validitas, pentingnya hasil atau importancy, dan aplikabilitas atau applicability (VIA) berdasarkan kriteria dari Centre for Evidence-Based Medicine (CEBM) untuk studi terapi. Berdasarkan kriteria inklusi yang ditetapkan, didapatkan satu artikel systematic review/meta-analisis (SR/MA) dari Randomised Clinical Trial (RCT) dan satu artikel RCT yang selanjutnya dikaji secara kritis dari aspek validitas, signifikansi, dan aplikabilitas. Kedua studi menunjukkan suplementasi vitamin D sebagai terapi tambahan memiliki pengaruh signifikan terhadap peningkatan berat badan pada pasien tuberkulosis paru.
Zinc Intake and Appetite in Patients with Post-Tuberculosis Lung Disease at Persahabatan National Respiratory Referral Hospital, Jakarta Mahardhika, Linda; Nurwidya, Fariz; Singal, Anna Maurina; Sutanto, Krisadelfa; Imaniar, Rania; Syam, Shaogi
Jurnal Respirasi Vol. 11 No. 3 (2025): September 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.3.2025.232-240

Abstract

Introduction: After completion of pulmonary tuberculosis (TB) treatment, some people may continue to experience respiratory issues that can progress into post-TB lung disease (PTLD). Individuals with PTLD exhibit suboptimal nutritional status. The loss of appetite is a significant factor influencing nutritional status. Zinc plays a role in hunger control.  Lack of zinc reduces taste sensitivity and food intake. This study examined the relationship between zinc intake and appetite in patients with PTLD at Persahabatan National Respiratory Referral Hospital, Jakarta. Methods: This cross-sectional study was conducted at Persahabatan National Respiratory Referral Hospital, Jakarta, from November 2024 to March 2025. Eighty-five adult patients with PTLD were included. Zinc intake was assessed by a semi-quantitative food frequency questionnaire (SQ-FFQ) and analyzed by NutriSurvey software. Appetite was measured using the visual analog scale (VAS) for appetite. Results: A total of 85 subjects participated in the study, comprising 78.8% males and 21.2% females. The average daily zinc intake was 4.4 mg/day, and 92.9% of the subjects had zinc intake below the recommended dietary allowance (RDA). The average VAS appetite score was 70 mm. A significant positive correlation was found between zinc intake and appetite, indicating that a decrease in zinc intake might result in a reduced appetite (r=0.266, p=0.014). Conclusion: Zinc intake is positively associated with appetite in patients with PTLD. Therefore, zinc intake monitoring is essential for supporting nutritional recovery and lung function in PTLD.
Hubungan Antara Asupan Energi dengan Rasio Neutrofil Limfosit pada Pasien Sakit Kritis Dian Purwantini; Yohannessa Wulandari; Diana Sunardi; Krisadelfa Sutanto; Wina Sinaga; Diyah Eka Andayani
Majalah Kedokteran Indonesia Vol 75 No 2 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.2-2025-1760

Abstract

Introduction: Critically-ill patients experience catabolic stress and inflammatory responses resulting in increased catabolism to meet energy demands. Neutrophil lymphocyte ratio (NLR) is used to assess immune and stress responses. Method: This study was a cross-sectional study of subjects aged ≥18 years admitted to the intensive care unit of Dr. Cipto Mangunkusumo National Central General Hospital and University of Indonesia Hospital. The characteristics of the study subjects included age, gender, nutritional status, diagnosis of ICU admission, protein intake, fat intake, and carbohydrate intake. Bivariate analysis was performed to evaluate the correlation between energy intake and neutrophil-lymphocyte ratio.Result: There were 44 subjects with a median age of 55 years (19-86). Nutritional status based on body mass index (BMI) obtained 31.8% normal nutritional status, 20.5% severe malnutrition, 25% obesity grade 1. The most common diagnoses were surgery and trauma 20.5% of subjects and sepsis 20.5% of subjects. Median RNL was 10.39 (2.51-59.5), energy intake was 10.5 (3-29) kcal/kg BW/day, protein intake was 0.4 (0-1.2) g/kg BW/day, fat intake was 18 (0-29)% and carbohydrate intake was 92 (23-184) g/day.Conclusion: There was no correlation between energy intake and NLR.
Peran Suplementasi Omega-3 Terhadap Nafsu Makan Pada Pasien Tuberkulosis Paru: Evidence-Based Case Report Melissa Mauli Sibarani; Krisadelfa Sutanto
Jurnal Ilmu Kedokteran dan Kesehatan Vol 13, No 5 (2026): Volume 13 Nomor 5
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v13i5.23435

Abstract

Tuberkulosis (TB) masih menjadi masalah kesehatan global dan sering berhubungan dengan malnutrisi akibat peningkatan kebutuhan metabolik, inflamasi sistemik, dan penurunan nafsu makan. Asam lemak omega-3 (ω-3 fatty acids) memiliki sifat antiinflamasi yang berpotensi membantu regulasi nafsu makan dan pemulihan status gizi pada pasien TB. Evidence-based case report ini bertujuan mengevaluasi peran suplementasi omega-3 terhadap nafsu makan pada pasien tuberkulosis paru. Penelusuran literatur dilakukan melalui PubMed, ScienceDirect, dan Google Scholar menggunakan kriteria eligibilitas yang telah ditetapkan. Telaah kritis dilakukan menggunakan Oxford Centre for Evidence-Based Medicine (CEBM) dan kerangka telaah kritis FAITH. Dua studi memenuhi kriteria inklusi, terdiri atas satu randomized controlled trial dan satu studi observasional. Tingkat evidensi berkisar antara Level 2 hingga Level 4 dengan kualitas metodologi sedang. Satu penelitian menunjukkan tidak terdapat hubungan bermakna antara rasio asupan omega-3/omega-6 dengan skor nafsu makan (r = −0,10; p = 0,54), sedangkan penelitian lain menunjukkan perbaikan indeks massa tubuh dan parameter inflamasi tanpa penilaian langsung terhadap nafsu makan. Bukti ilmiah saat ini belum cukup untuk menyimpulkan bahwa suplementasi omega-3 secara langsung meningkatkan nafsu makan pada pasien TB paru. Namun, suplementasi omega-3 berpotensi memberikan manfaat antiinflamasi dan dukungan status gizi sebagai terapi adjuvan. Jumlah studi yang terbatas, heterogenitas luaran, pengukuran nafsu makan yang tidak langsung, dan ukuran sampel kecil menjadi keterbatasan utama bukti ilmiah yang tersedia.
Co-Authors Anna Maurina Singal arieska felicia Chandra, Dian Novita Dewi Friska Dewi Wulandari Dian Purwantini Diana Sunardi Diana Sunardi Diyah Eka Andayani Fariz, Nurwidya Fiastuti Witjaksono Fiastuti Witjaksono Fiastuti Witjaksono Githa Putri Puspita Sari Githa Putri Puspita Sari Handayani Eka Puspita Sari Ibrahim Agung K.N, Beta Novianti Karlina Lestari Linda Mahardhika Melissa Mauli Sibarani Ninik Mudjihartini Nurul Ratna Mutu Manikam Paramita, Dewita Nina Paramita Putri Novia Choiri Insani Rania Imaniar Singal, Anna Maurina Syam, Shaogi Tarafainy Basalamah Tirza Z Tamin Wahyu Ika Wardhani Wiji Lestari Wiji Lestari Wina Sinaga Wulandari, Indah Sri Yohannessa Wulandari Yosephine Santoso