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Association of Antiplatelet Type on Length of Stay and Neurological Outcomes in Ischemic Stroke Aprillia Wardhani, Firdha
Pharmaceutical Journal of Indonesia Vol. 10 No. 2 (2025)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Antiplatelet therapy plays an important role in preventing the progression of ischemic stroke. However, the effectiveness of different types of antiplatelet agents in improving clinical outcomes still requires further investigation. This study aimed to analyze the relationship between the type of antiplatelet used and the clinical outcomes of hospitalized ischemic stroke patients, based on changes in the National Institutes of Health Stroke Scale (NIHSS) score and length of stay (LoS). This research was a retrospective cross-sectional observational study involving 92 hospitalized patients with ischemic stroke. Patients were grouped based on the antiplatelet therapy received: Clopidogrel (CPG) (n=58), Aspirin (n=17), and dual antiplatelet therapy (DAPT) with Clopidogrel + Aspirin (n=17). Of the total patients, 43 (46.7%) showed improvement in NIHSS score, while 49 (53.2%) did not. The mean LoS was 7.033 days. The proportion of patients with NIHSS improvement by treatment group showed that the CPG group had the highest percentage of improvement, with 30 out of 58 patients (51.72%), compared to Aspirin 7/17 (41.2%) and DAPT 6/17 (35.3%). However, statistical analysis revealed no significant association between the type of antiplatelet and NIHSS improvement (p = 0.431). In addition, Kruskal-Wallis analysis revealed no significant association between LoS and antiplatelet type (p = 0.429). These findings suggest that other factors may play a more substantial role in determining the clinical outcomes of ischemic stroke patients. Keywords: antiplatelet, clinical outcome, NIHSS, ischemic stroke, LoS
The Role of Information Technology and Product Innovation on the Competitive Advantage of Companies at Jember East Java Cendekiawan, Khrisna Agung; Wardhani, Firdha Aprillia
JAKI : Jurnal Akuntansi Vol 2 No 1 (2025): Dirya : Journal of Economic Management
Publisher : Pascasarjana STIE Miftahul Huda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70283/dirya.v2i1.76

Abstract

This study aims to analyze the role of information technology and product innovation in creating a competitive advantage for companies in Jember, East Java. Competitive advantage is a critical factor in determining the survival and success of companies in an increasingly competitive market. Using a qualitative research method, this study explores the perspectives of key stakeholders within companies regarding the implementation of information technology and product innovation. In-depth interviews with company leaders, along with secondary data analysis, were employed to gain insights into how these two factors contribute to the company’s strategy. The findings of this study reveal that information technology plays a crucial role in enhancing operational efficiency, internal communication, and facilitating access to global markets. Additionally, product innovation proves to be a key differentiator for companies, enabling them to meet the ever-evolving needs of consumers. The research also highlights that companies successfully integrating both elements are able to build and sustain a competitive advantage. Overall, the findings demonstrate the importance of adapting to new technologies and continuously innovating in order to maintain a company’s competitiveness in the digital era.
Penyuluhan Interaktif Tentang Pubertas dan Kesehatan Reproduksi Remaja bagi Siswa SMP Negeri 14 Jember Eryani, Mikhania Christiningtyas; Winarti, Lina; Wardhani, Firdha Aprilia
Jurnal Pengabdian UNDIKMA Vol. 5 No. 4 (2024): November
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v5i4.12879

Abstract

This community service activity aims to increase the knowledge of students of SMP Negeri 14 Jember regarding puberty and reproductive health in order to realize healthy adolescents for Indonesia Emas 2045. The method used in this activity is the interactive counseling method. The evaluation instrument for this community service is a questionnaire and is analyzed descriptively qualitatively and quantitatively. The results of the community service show that there is an increase in student knowledge which initially had a score of 41.4 before the counseling to 84.1 after the counseling. So that the increase in participant scores after the community service process was carried out was 42.7 or 103%. Through this community service activity, adolescents at SMP Negeri 14 Jember increased their knowledge, especially regarding puberty and reproductive health.
Baricitinib for the treatment of COVID-19 Firdha Aprillia Wardhani; Syafika, Devina Sarah; Kusumaningrum, Yunita Dyah; Adelia Firandi
Journal of Agropharmacy Vol. 1 No. 2 (2024)
Publisher : Faculty of Pharmacy, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/joa.v1i2.1422

Abstract

Baricitinib which is one of the therapies for rheumatoid arthritis is a JAK inhibitor. WHO recommended therapy with the combination of baricitinib and corticosteroids in COVID-19 patients with severe or critical condition. Effectivity and safety assessment of Baricitinib use were carried out by reviewing the literature published between December 2019 – February 2022, and showed that the use of Baricitinib in COVID-19 patients resulted in an improvement of lung function, improvement of oxygen saturation, higher recovery rate, and lower mortality, with similar adverse event incidence. A loading dose or a higher dose can be recommended for patient with caution and consideration of higher possibility in the incidence of adverse events
Evaluasi Perencanaan dan Pengadaan Obat dengan Dana JKN di Puskesmas Rambipuji Jember Norcahyanti, Ika; Firandi, Adelia; Ramadhani, Nuril Izzati Farihatur; Rachmawati, Sinta; Rachmawati, Ema; Aryani, Dhita Evi; Wardhani, Firdha Aprillia; Kusumaningrum , Yunita Dyah
Journal of Agropharmacy Vol. 1 No. 3 (2024)
Publisher : Faculty of Pharmacy, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/joa.v1i3.1811

Abstract

Public Health Center is a health facility that organizes drug management activities, including planning and procurement activities. Evaluation needs to assess the success of achieving the objectives and results of the action. Indicators that can use are efficiency indicators published by the Ministry of Health of the Republic of Indonesia and efficiency indicators developed by Pudjaningsih. Rambipuji Public Health Center with spending funds for the most significant drug procurement in Jember Regency in 2020. Therefore, it is necessary to evaluate the results that can improve the quality of service in the next period. This research aims to determine the results of the evaluation of drug planning and procurement with JKN funds at Rambipuji Public Health Center for 2020. This research is descriptive, primary data through interview results. Secondary data includes total funds available, drug procurement funds, Drug Usage Reports, and Drug Demand Sheets for drugs purchased through JKN funds and stock cards. The data is analyzed descriptively, presented in the form of tables supported by interview results. The results showed that the Government of Indonesia had governed drug planning and procurement activities with JKN funds. The percentage indicator of available funds compared to the general funds needed is 114.26%. The percentage indicator of drug procurement fund allocation is 3.46%. Results on percentage indicator procurement conformity with the reality of the use of each drug item amounted to 133.33% and on the procurement frequency indicator of each drug item once a year. Through this research, it can be concluded that the evaluation results on indicators of the efficiency of drug planning and procurement activities at Rambipuji Public Health Center have not been by established standards. This matter was influenced by several factors, including a decrease in the number of patient visits due to the COVID-19 pandemic, changes in the organizational structure in the Jember Health Office that resulted in the frequency of procurement activities only once throughout 2020, and the absence of government regulations that regulate in more detail about the percentage of JKN funds allowed for drug procurement activities.
Peningkatan Edukasi Stroke Masyarakat dengan Video Edukasi Stroke – “CHERIE” (Cerebral Hemorrhage and Ischemic Educational Video) Wardhani, Firdha Aprillia; Amalia Wardatul Firdaus; Shinta Mayasari
Jurnal Pengabdian Masyarakat (JUDIMAS) Vol. 1 No. 2 (2023)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat STIKes Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/judimas.v1i2.163

Abstract

Berdasarkan data Kementerian Kesehatan, stroke merupakan penyebab kematian pertama untuk semua umur dengan persentase 15,4 persen, dan stroke juga menempati urutan pertama penyakit tidak menular yang mematikan. Time window yang ditujukan untuk pengobatan stroke adalah tiga jam, sehingga pengenalan gejala stroke sedini mungkin kepada masyarakat sangat penting. Tujuan Pengabdian masyarakat ini adalah untuk mengedukasi masyarakat dengan video edukasi stroke CHERIE (Cerebral Hemorrhage and Ischemic Educational Video) bagi masyarakat untuk lebih memahami penyakit stroke, mulai dari gejala hingga petunjuk penggunaan obat. Sasaran kegiatan ini adalah masyarakat umum di wilayah kabupaten Jember. Metode yang digunakan adalah memberikan edukasi dan mengukur tingkat pengetahuan melalui pretest dan post-test untuk mengetahui perubahan tingkat pengetahuan. Hasil dari kegiatan ini, sasaran mengalami peningkatan pengetahuan dengan rata-rata 42,8%, dengan nilai rata-rata pretest sebesar 68, dan rata-rata nilai post-test sebesar 95,3. Sehingga dapat disimpulkan bahwa kegiatan Pengabdian masyarakat dalam Upaya peningkatan edukasi masyarakat mengenai stroke melalui video CHERIE cukup efektif dalam meningkatkan pengetahuan masyarakat.