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All Journal Majalah Kedokteran Gigi Indonesia Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Journal of Dentomaxillofacial Science Interdental Jurnal Kedokteran Gigi (IJKG) Indonesian Journal of Dental Medicine Indonesian Journal of Prosthodontics
Ratri Maya Sitalaksmi
Department Of Prosthodontics, Faculty Of Dental Medicine, Universitas Airlangga, Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

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Utilization of robusta coffee bean extract (Coffea canephora) as an alternative herbal in applied dentistry Muhammad Dani Anko Putra; Putri Namira Zahrani; Sherly Giovani Pang; Fahmida Amira Hapsari; Ratri Maya SItalaksmi
Indonesian Journal of Prosthodontic Vol 5 No 2 (2024): December 2024
Publisher : Indonesia Prosthodontic Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46934/ijp.v5i2.272

Abstract

Background: Indonesia is a major producer of Robusta coffee, which has variations in chemical qualities such as caffeine, polyphenols, flavonoid compounds, tannins, alkaloids, and chlorogenic acid. Research shows that Robusta coffee bean extract has potential in dental applications. The importance of Robusta coffee as an agricultural commodity and source of active ingredients with health benefits, especially in dental care. Objectives: This literature review aims to evaluate the effectiveness of Robusta coffee as oral herbal medicine. An electronic search was carried out on PubMed, Science Direct, and Google Scholar with manual search from 2018 to 2024 following the PRISMA 2020 guidelines. The review incorporated studies related to the utilization of Robusta coffee bean extract that can be applicable for oral health care. Conclusion: Robusta coffee bean extract has significant potential as an active material in dental health care, with clear antibacterial, antioxidant, and wound-healing abilities. Robusta coffee bean extract-based products as oral herbal medicine can give significant advantages to oral health. Further research is needed to optimize its use in health products.
Interrelationship of body mass index, dental caries, and oral health behaviour: Insights from Primary School in Surabaya, Indonesia Sitalaksmi, Ratri Maya; Kartikasari, Nadia; Rahmania, Primanda Nur; Limantoro, Onny Eryanto; Wardati, Yora; Prajugo, Charlie Saputra; Yukuri, Annete Juwita; Putri, Hananah Oktalidial; Dhamayanti, Tiara Eva; Rudhanton, Riddo Adli; Gofur, Aisyah Rachmadani Putri
Indonesian Journal of Dental Medicine Vol. 8 No. 1 (2025): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v8i1.2025.12-18

Abstract

Background: Dental caries is one of global health issues, with various factors such as Body Mass Index (BMI) and oral hygiene behaviours influencing its prevalence. Understanding the relationship between BMI and dental caries, as well as the oral hygiene practices, is essential for developing effective prevention strategies. Interventions on these factors arevital for mitigating the effects of dental caries on overall health. Purpose: This study aims to examine the correlation between dental caries and BMI in relation to oral and dental health behaviours. Methods: BMI and Decay, Missing, and Filled Teeth (DMF-T) data were collected from 5th-grade elementary school students, along with responses to an Oral andDental Health Care Questionnaire. Statistical analysis was conducted using the Kruskal-Wallis Test (p<0.05) and DwassSteel-Critchlow-Fligner (DSCF) (p<0.05). Results: No significant differences in caries indices were observed between genders (p>0.05). The majority of participants were classified as underweight, and this group demonstrated a lower caries index. A comparison of DMF-T scores across various BMI categories revealed a statistically significant difference (p<0.05). Furthermore, the post hoc test indicated a significant difference in BMI between the very low and low groups within the DMFT category (p<0.05). Conclusion: The findings suggest that good oral health practices is affecting the relationship between BMI and dental caries. Thus, the importance of promoting proper oral hygiene and early intervention to prevent dental caries and improve overall health outcomes. Preventive efforts should target at-risk groups, focusing onlifestyle and oral health education.
Characterization nanosuspension formulated with Graptophyllum pictum (L.) Griff extract and hydroxyapatite as bone graft material: experimental laboratory study Bilbalqish, Kavanila; Rianti, Devi; Sitalaksmi, Ratri Maya; Shariff, Khairul Anuar bin
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 1 (2025): April 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i1.59462

Abstract

ABSTRACT Introduction: Hydroxyapatite is a major component of the inorganic minerals in the hard tissues of humans and has been widely used as a biomedical ceramic material in orthopedic and dentistry applications. Adding natural ingredients such as Graptophyllum pictum can increase the anti-inflammatory properties due to the presence of phenolic compounds and alkaloids. The aim of this study was to determine the characterization nanosuspension formulated with Graptophyllum pictum (L.) Griff extract and hydroxyapatite. Methods: Nanosuspension were characterized using Scanning Electron Microscopy (SEM), Electron Dispersive X-ray analysis (EDX), Fourier Transform Infrared Spectroscopy (FTIR), and Liquid Chromatography Mass Spectrometry (LCMS). These evaluations were to reveal the surface morphology, elemental composition, functional groups, and identify the active metabolite of the nanosuspension. Results: SEM revealed the morphology agglomeration of spherical hydroxyapatite particles. The EDX analysis revealed a content of carbon, oxygen, sodium, phosphorus, chlorine, potassium, and calcium with Ca/P ratio 1.47. The FTIR analysis identified hydroxyl, water molecules, carbonate, carbonyl, and phosphate groups in the sample. LC-MS analysis identified 49 active metabolites such as phenols, alkaloid, fatty acids and their derivatives, amino acids, carbohydrates, carboxylic acids, alcohols, and ketones from the sample. Conclusion: The characteristics of nanosuspension formulated with Graptophyllum pictum (L.) Griff extract and hydroxyapatite are similar to those of natural bones. Keywordscharacterization, Graptophyllum pictum, hydroxyapatite, nanosuspension Karakterisasi nano suspensi ekstrak Graptophyllum pictum (L.) Griff dan hidroksiapatit sebagai material bone graft: penelitian eksperimental laboratoris ABSTRAK Pendahuluan: Hidroksiapatit merupakan komponen utama mineral anorganik pada jaringan keras manusia dan telah banyak digunakan sebagai keramik di bidang biomedis ortopedi dan kedokteran gigi. Penambahan bahan alami seperti Graptophyllum pictum dapat meningkatkan sifat antiinflamasi karena adanya senyawa fenolik dan alkaloid. Tujuan penelitian ini adalah mengetahui karakterisasi nanosuspensi yang diformulasikan dengan ekstrak Graptophyllum pictum (L.) Griff dan hidroksiapatit. Metode: Nanosuspensi dikarakterisasi menggunakan Scanning Electron Microscopy (SEM), Electron Dispersive X-ray analysis (EDX), Fourier Transform Independent Spectroskopi (FTIR), dan Liquid Chromatography Mass Spectrometry (LCMS). Evaluasi ini dilakukan untuk menunjukkan morfologi permukaan, komposisi unsur, gugus fungsi, dan mengidentifikasi metabolit aktif nanosuspensi. Hasil: SEM menunjukkan aglomerasi morfologi partikel hidroksiapatit berbentuk bulat. Analisis EDX menunjukkan kandungan karbon, oksigen, natrium, fosfor, klorin, kalium, dan kalsium dengan rasio Ca/P 1,47. Analisis FTIR mengidentifikasi gugus hidroksil, molekul air, karbonat, karbonil, dan fosfat dalam sampel. Analisis LC-MS mengidentifikasi 49 metabolit aktif seperti fenol, alkaloid, asam lemak dan turunannya, asam amino, karbohidrat, asam karboksilat, alkohol, dan keton dari sampel. Simpulan: Karakteristik nanosuspensi yang diformulasikan dengan ekstrak Graptophyllum pictum (L.) Griff dan hidroksiapatit mirip dengan tulang alami. Kata kuncikarakterisasi, Graptophyllum pictum, hidroksiapatit, nanosuspensi
Mechanical cleansing effect using purple leaf denture cleanser on Candida albicans Sitalaksmi, Ratri Maya; Parahita, Calista Arin; Ahmad, Fahmi; Wijaya, Tomy Aji; Sinaga, Nimas Ulinar Damessa; Syafa’ati, Laitlatul Maghfiroh
Indonesian Journal of Dental Medicine Vol. 9 No. 1 (2026): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v9i1.2026.7-11

Abstract

Background: Denture stomatitis is experienced by 65% of denture wearers and is generally caused by Candida albicans colonization on the porous surface of acrylic resin. The use of chemical denture cleansers can increase surface roughness and discoloration of the resin, so a natural alternative is needed. Purple leaf extract (Graptophyllum pictum) contains flavonoids that have the potential to be used as a natural denture cleanser with antifungal activity against Candida albicans. Purpose: This study aims to investigate the antifungal potential of purple leaf extract (G. pictum) in the form of denture cleaning soap that effectively inhibits the growth of C. albicans, the cause of denture stomatitis. Methods: This true experimental study used a post-test-only control group design with three groups: K(-) aquades, K(+) baby soap, and P (50% G. pictum extract soap), each consisting of 9 samples. Acrylic resin plates were brushed for 5 seconds per side, rinsed with PBS, incubated on SDA at 37°C for 24 hours, and the number of C. albicans colonies was counted. Data were analyzed using the Kruskal–Wallis and Mann–Whitney tests (p<0.05). Results: Mean C. albicans growth was 90.55 ± 8,54 (K-), 10.55 ± 1.58 (K+), and 20.22 ± 4.05 (P). Significant differences were found among all groups (p<0.05). Conclusion: Denture cleanser containing G. pictum extract reduced C. albicans growth significantly, the extract shows potential as a natural antifungal ingredient for denture cleansers.
Antibacterial properties of herbal denture cleanser based on Graptophyllum pictum L. Griff. leaves Nadia Kartikasari; Ratri Maya Sitalaksmi; Muhammad Rafi Nurfaiz Arifin; Aurelia Della Imani; Agus Dahlan; Harry Laksono; Aisyah Rachmadani Putri Gofur
Dental Journal (Majalah Kedokteran Gigi) Vol. 59 No. 2 (2026): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v59.i2.p134-140

Abstract

Background: Removable partial dentures (RPDs) are one therapeutic option for tooth loss replacement. Despite its high absorption and porous qualities, acrylic resin—which is frequently used as the base material for RPDs—may encourage the growth of microorganisms and the development of plaque. Graptophyllum pictum L. Griff (G. pictum) has been commonly used in herbal medicine due to its pharmacological effects, which include immunomodulatory, antioxidant, anti-inflammatory, antibacterial, and antifungal activities. Purpose: This study aims to assess the antibacterial properties of an herbal denture cleanser based on G. pictum in effervescent granule against Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa). Methods: The antibacterial activity was examined using the spread plate method at different time points. The number of Aa and Pg bacteria was determined using colony-forming units (CFUs) and bactericidal ratio (BR%). The statistical analysis employed the Kruskal–Wallis and post-hoc Mann–Whitney U tests (P < 0.05). Results: The results indicate that the herbal cleanser’s antibacterial effectiveness against Aa and Pg increased significantly over time, reaching its optimal level after a 15-minute soaking period, as evidenced by the CFUs and BR%. Conclusion: The herbal denture cleanser based on G. pictum demonstrated antibacterial properties against Pg and Aa, which are significant pathogens in oral infections. These results indicate that this herbal formulation has potential as an effective alternative for future denture cleaning applications.
Co-Authors Agus Dahlan Ahmad, Fahmi Aisyah Rachmadani Putri Gofur Aldrian, David Alexander Patera Nugraha Aljunaid, Mohammed Ahmed Qasim Saleh Amalia, Nadya Rafika Andaru, Salsabilla Eliya Atikasari, Nurani Aurelia Della Imani Batul, Fatimah Bilbalqish, Kavanila Chairuly, Hadfi Dhaky Charyadie, Arlita Gladys Tricia Devi Rianti Dewanty, Zaravia Dhamayanti, Tiara Eva Dhywinanda, Devin Elysia Dien, Sinta Nuriyah Fahmida Amira Hapsari Giyansyah, Nadya Savira Gofur, Aisyah Rachmadani Putri Gunawan, Hendri Budi Hanoem Eka Hidajati Harly Prabowo, Harly Harry Laksono, Harry Karina Mundiratri Lestari, Kurnia Ayu Limantoro, Onny Eryanto Mefina Kuntjoro Meinar Nur Ashrin Muhammad Dani Anko Putra Muhammad Dimas Aditya Ari Muhammad Rafi Nurfaiz Arifin Nadia Kartikasari Nadia Kartikasari, Nadia Nadya Savira Giyansyah Nastiti Faradilla Ramadhani Noor, Tengku Natasha Eleena binti Tengku Ahmad Parahita, Calista Arin Prajugo, Charlie Saputra Primanda Nur Rahmania Putri Namira Zahrani Putri, Hananah Oktalidial Real Akbar Aucky Sanjaya Rostiny Rostiny, Rostiny Rudhanton, Riddo Adli Sakti, Gilang Ratri Setiawan, Panji Adhytama Pragana Setiyana, Viola Stevy Shallomitha, Aginta Gracia Shariff, Khairul Anuar Shariff, Khairul Anuar bin Sherly Giovani Pang Sherman Salim, Sherman Sinaga, Nimas Ulinar Damessa Syafa’ati, Laitlatul Maghfiroh Tandra, Renata Jasmine Ramadhanty Felisha Tasya Regita Pramesti Theresia Indah Budhy Sulisetyawati Utami, Farasty Utami, Firdha Putri Utari Kresnoadi Valerian Laksono Viola Stevy Setiyana Wardati, Yora Wijaya, Tomy Aji Yukuri, Annete Juwita Zaravia Dewanty