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EFEKTIVITAS PENAMBAHAN ASAM ASKORBAT PADA KOMBINASI AMOKSILIN-KLARITROMISIN DALAM MENGHAMBAT PERTUMBUHAN HELICOBACTER PYLORI Ardhiyanti Puspita Ratna
JURNAL KEDOKTERAN Vol 1 No 2 (2016)
Publisher : Fakultas Kedokteran Universitas Islam Al-Azhar

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Abstract

Helicobacter pylori adalah bakteri gram negatif berbentuk spiral yang menjadi penyebab gastritis superficialis kronis, yang kemudian berkembang menjadi adenocarcinoma gaster. Terapi yang saat ini digunakan adalah kombinasi Amoksilin-Klaritromisin yang berkerja bersama merusak dinding sel bakteri dan mengganggu proses sintesa proteinnya. Karena tingginya tingkat kegagalan terapi, maka muncul alternatif terapi yaitu penambahan asam askorbat, yang diduga bekerja dengan merubah pH lingkungan dan antioksidan. Tujuan penelitian ini untuk membuktikan efektifitas penambahan asam askorbat pada kombinasi Klaritromisin dan Amoksilin. Penelitian eksperimental eksploratif ini dilakukan di Unit Riset Biomedik RSUD Mataram, bulan September 2007. Subyek penelitian adalah biakan Helicobacter pylori di BAP dalam kondisi mikroaerofilik. Pengambilan sampel menggunakan total sampling. Data yang diambil adalah diameter zona inhibisi yang terbentuk pada biakan, dengan metode uji difusi cawan, menggunakan kombinasi Amoksilin 10 µg dan Klaritromisin 5 µg, sebagai kontrol, sedangkan perlakuan digunakan Amoksilin 10 µg dan Klaritromisin 5 µg ditambah asam askorbat dosis 31,5 µg , 62,5 µg , 125 µg , 250 µg , dan 500 µg. Dianalisa menggunakan ANOVA, Uji Duncan dan Uji Korelasi Regresi. Hasil penelitian membuktikan penambahan asam askorbat pada kombinasi amoksilin-klaritromisin bisa meningkatkan diameter zona inhibisi (p= 0,029), sedangkan KHM penambahan asam askorbat adalah 125 µg. Uji korelasi regresi menunjukkan hubungan lemah penambahan asam askorbat dengan peningkatan diameter zona inhibisi (r2=0,259). Kesimpulannya penambahan asam askorbat pada kombinasi Amoksilin – Klaritromisin dapat meningkatkan diameter zona inhibisi dan Kadar Hambat Minimum penambahan asam askorbat pada dosis 125 µg.
Edukasi tentang Manajemen Risiko Keselamatan dan Kesehatan Kerja di CV.AVN General Contractor Malang Anindya Hapsari; Tika Dwi Tama; Dian Mawarni; Ardhiyanti Puspita Ratna
Journal of Community Engagement and Empowerment Vol 5, No 1 (2023)
Publisher : Institut Ilmu Kesehatah Bhakti Wiyata Kediri

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Abstract

Masalah keselamatan kerja di Indonesia telah lama mendapat perhatian dan dukungan dari pemerintah sejak ditetapkannya Undang-Undang Keselamatan Kerja Nomor 1 Tahun 1970. Bahkan sejak tahun 1993, keselamatan kerja telah ditingkatkan untuk mencapai kecelakaan nihil (zero accident) pada setiap proses produksi.  Setiap pekerjaan selalu mengandung potensi risiko bahaya dalam bentuk kecelakaan kerja, besarnya potensi kecelakaan dan penyakit akibat kerja tergantung dari jenis produksi, teknologi yang dipakai, bahan yang digunakan, tata ruang dan lingkungan serta kualitas manajemen dan tenaga pelaksana. Maka dari itu pelaksanaa K3 (Keselamatan dan Kesehatan Kerja) sangat penting diterapkan dalam berbagai jenis pekerjaan untuk mengurangi atau bahkan meniadakan potensi risiko bahaya yang berakibat keceelakaan. Oleh karena itu, pihak pengabdi bermaksud untuk mengadakan pengabdian pada CV.AVN dengan judul “Edukasi tentang Manajemen Risiko Keselamatan dan Kesehatan Kerja di CV.AVN General Contractor” untuk meningkatkan derajat kesehatan masyarakat, khususnya pihak manajemen dan pegawai CV.AVN. Metode yang digunakan dalam kegiatan ini adalah pre dan post test. Hasil kegiatan ini menunjukkan ada peningkatan nilai rata-rata sebelum diberi penyuluhan sebesar 49,33 dan setelah diberikan penyuluhan sebesar 79. Hasil analisis statistik menunjukkan nilai p value < 0,05 menunjukkan bahwa ada perbedaan pengetahuan sebelum dan sesudah diberikan penyuluhan. Kesimpulan kegiatan ini adalah pmberian edukasi melalui penyuluhan sangat efektif dalam meningkatkan pengetahuan karyawan dan pihak manajemen CV.AVN General Contractor tentang pentingnya Keselamatan dan Kesehatan Kerja.
Pendampingan Kesehatan (Tim Medis) Kegiatan Wisata di Gunung Bromo Ronal Surya Aditya; Ardhiyanti Puspita Ratna; Dinta Sugiarto; Nurul Evi; Eri Yanuar Akhmad Budi Sunaryo; Qory Tifani Rahmatika; Yhenti Widjayanti; Muhammad Putra Ramadhan; Achmad Masfi
Jurnal Nusantara Mengabdi Vol. 2 No. 3 (2023): Juni
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/jnm.v2i3.1947

Abstract

Purpose: To ensure the safety and health of tourists. They also play a role in maintaining the security of tourists in the area. In addition, the accompanying medical team can also provide health services such as light health checks, simple medical procedures, and providing health information to tourists. Methodology: The target is foreign students who are on holiday in Bromo, with the criteria of students taking comparative studies at Malang State University and attending Malang. This will make it easier for the medical team to provide emergency medical care if there are tourists who need it. This aims to monitor the health of tourists and provide first aid if there are tourists who need it. Must-have medical equipment such as defibrillators, oxygen, resuscitation equipment, and so on. This can include how to manage common health symptoms and steps to prevent disease. Results: Several cases were encountered in the health assistance, namely: bruises (contusions), cramps and bleeding. Overall tourists can return to health and return from Bromo without any comorbidities. Conclusion: Traveling to the mountains can cause serious injury if proper precautions are not taken. In addition, it is important to follow the guidelines given by experienced climbers, avoid trails that are too dangerous, and not take excessive risks when doing activities on the mountain. With proper preparation and wise precautions, we can reduce the risk of injury and enjoy a safe and enjoyable mountain travel experience.
Pengaruh Variasi Latihan Dalam Peningkatan Kondisi Fisik (Keseimbangan, Kekuatan, Dan Kelentukan) Anggota Ekstrakurikuler Ju-Jitsu Dojo SMK Cendika Bangsa Kepanjen Kabupaten Malang Yogam Prathista Hare Putra; Sapto Adi; Ardhiyanti Puspita Ratna
Atmosfer: Jurnal Pendidikan, Bahasa, Sastra, Seni, Budaya, dan Sosial Humaniora Vol. 1 No. 4 (2023): November: Jurnal Pendidikan, Bahasa, Sastra, Seni, Budaya, dan Sosial Humaniora
Publisher : Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/atmosfer.v1i4.340

Abstract

This research aims to determine the effect of variations in training in the form of IPPON in improving the physical condition (balance, strength and flexibility) of members of the extracurricular Ju-jitsu Dojo SMK Cendika Bangsa Kepanjen, Malang Regency. The study design used was the one group pretest-posttest design. The population in this study was 20 people and sampling used purposive sampling technique and a sample of 17 respondents were obtained who participated in the research. The independent variable is IPPON, the dependent variable is physical condition (balance, strength and flexibility). The results of the paired t-test prove that the IPPON variable has no significant influence on the balance variable with a significance result of 0.818 (P Value > 0.05) with an average pre-test of 20.38 and post-test of 19.56, while in the strength variable there is significant influence with a significance result of 0.000 (P value > 0.05) with a pre-test average of 29.18 and post-test 35.12, for the flexibility variable there is also a significant influence with a significance result of 0.000 (P value > 0.05 ) with an average pre-test of 14.56 and post-test of 18.53.
Pengaruh Latihan High Intensity Interval Training (HIIT) Terhadap Kadar Triglierida Pada Atlet Lari Jarak Jauh Pasi Kota Malang Dimas Pratama Putra; Rias Gesang Kinanti; Ardhiyanti Puspita Ratna
Atmosfer: Jurnal Pendidikan, Bahasa, Sastra, Seni, Budaya, dan Sosial Humaniora Vol. 1 No. 4 (2023): November: Jurnal Pendidikan, Bahasa, Sastra, Seni, Budaya, dan Sosial Humaniora
Publisher : Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/atmosfer.v1i4.385

Abstract

Triglycerides are fats carried by the lipoprotein system located in the blood, are the main cause of arterial diseases and are usually compared with cholesterol using lipoprotein electrophoresis. Triglycerides consist of glycerol linked to fatty acid groups. The High Intensity Interval Training method is a sport designed to increase metabolism and burn body fat so as to balance triglyceride levels in the body. This exercise is often included in training programs for long-distance runners. This study aims to obtain information about the effect of the High Intensity Interval Training (HIIT) exercise on the interval running model on triglyceride levels in PASI Athletes in Malang City. The research method and design used was an experiment in the form of the one group pretest-posttest design, namely recording the results of triglyceride levels before HIIT training and after HIIT training. This study involved 8 long-distance runners whose blood was taken from the cubital vein before the HIIT treatment. The design of this study was initiated by screening all research subjects according to predetermined inclusion criteria. And all subjects were instructed to fill out a willingness form (informed consent) then proceed with taking a blood sample before the HIIT exercise treatment of ± 10 µL. After taking blood, the HIIT training program is continued with an interval running model, namely by running fast for 2 minutes, then walking for 2 minutes, doing 10 repetitions. After completing the HIIT training treatment, all subjects took blood again as much as ± 10 µL. When all subjects' blood samples have been taken, it is followed by laboratory tests in the clinical pathology laboratory, Faculty of Medicine, Brawijaya University. The results of the study by conducting a paired sample T-test were used to analyze the data obtained with a significant (2-tailed) value of 0.938 greater than the p value of 0.05 (0.938> 0.05) indicating H0 was accepted and Ha was rejected which means that HIIT training has no significant effect on the leukocyte levels of PASI Athletes in Malang City. So it can be concluded that HIIT training has no effect on increasing leukocyte levels in PASI Athletes running long distances in Malang City. The conclusion in this study was that the HIIT training provided had no significant effect on the amount of triglycerides after and after exercise. Triglyceride levels in long-distance runners are at normal levels. This is because there has been regular practice given by the coach as preparation for the match.
Pengaruh Latihan Shadow Terhadap Kelincahan Footwork Siswa Ekstrakulikuler Bulutangkis Sekolah Menengah Atas Katolik ST. Albertus Malang Byan Bagas Bramudya; Sapto Adi; Ardhiyanti Puspita Ratna
Bersatu: Jurnal Pendidikan Bhinneka Tunggal Ika Vol 2 No 2 (2024): Maret : Jurnal Pendidikan Bhinneka Tunggal Ika
Publisher : LPPM Politeknik Pratama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51903/bersatu.v2i2.629

Abstract

As a fast-paced sport, badminton necessitates quick reflexes and agility on the court in order to hold and drop the shuttlecock into the opposing court. The goal of this research was to see how students in the badminton club at St. Albertus Catholic High School in Malang responded to shadow training to improve their agility. The research employed a pre-experimental strategy, specifically, a one-group pre-post test layout. There were two meetings per week for a total of eight weeks during this study. In order to get in shape, try this 6-point shadow training program. The shadow test was used as the instrument to gauge agility in this research. The t-test for paired samples was used to analyze the data in this study. The significance level of 0.000 for the t-test hypothesis test with paired samples t-test analysis is lower than the conventional threshold of 0.05. As a result, we can conclude that H1 is true and H0 is false. Students participating in badminton as an extracurricular activity at St. Albertus Catholic High School in Malang found that shadow training significantly improved their agility.
Effect of Combination Training Shuttle Runn and Zig-zag Run on the Agility of Male and Female Karate Athletes at the State University of Malang Nawawi, Muhammad; Adriana, Oliviana; Ratna, Ardhiyanti Puspita
Jurnal Kepelatihan Olahraga Vol 15, No 2 (2023)
Publisher : Fakultas Pendidikan Olahraga dan Kesehatan, Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jko-upi.v15i2.58317

Abstract

Karate is a branch of achievement sports that has a Kumite competition number. There are two athletes in the Kumite category in a karate match who face each other and must have agility when attacking and defending. The purpose of this study was to understand the effect of combination training of Shuttle Run and Zig-zag Run on the agility of male and female karate athletes at State University of Malang. This pre-experimental study used the One Group Pretest-Posttest Design. The population used was karate athletes at Malang State University with a total of 24 samples divided into male athletes and female athletes. The agility of karate athletes was assessed using the Illinois agility test at the pretest and post-test. Based on the analysis of the Paired Samples T Test, it showed that the combined Shuttle Run and Zig-zag Run exercises had a significance = 0.00 (p 0.05) for male athletes, while a significance value = 0.00 (p 0.05) for female athletes. Based on the findings of this study, the combined training of Shuttle Run and Zig-zag Run is effective in increasing the agility of male and female karate athletes at the State University of Malang
Combination of Moderate Intensity Exercise and Rose Petals Yoghurt Alters Blood Pressure and Soluble Rage Level in High Advanced Glycation End Products Diet Induced Wistar Rat Ratna, Ardhiyanti Puspita; Weningtyas, Anditri; Amelia, Widya Dana; Putra, Rexy Ichtiar Chesara
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1556

Abstract

A diet high in advanced glycation end products (AGEs) has been linked to an increased risk of hypertension and other vascular degenerative diseases. Some intervention such as moderate intensity exercise, yogurt probiotic intake and anthocyanin supplementation had been conducted separately, and showed promising effects. The aim of this study is to analyse the effect of combining rose petal yoghurt and moderate intensity exercise in lowering blood pressure and sRAGE level in high AGEs diet induced model. This research was experimental study, using post test-only control group design. The animals that were used were white male rats (Rattus norvegicus) Wistar strain, divided into 5 groups. Group KN was given standar diet, KP was treated with high AGEs diet, KA was treated with high AGEs diet and combination of rose yoghurt and moderate exercise, KB was given high AGEs diet dan rose yoghurt, and KC group was treated with high AGEs diet and moderate exercise. After 12 weeks systolic and diastolic blood pressure was examined using Kent Scientific CODA blood pressure analyzer and sRAGE examined with ELISA technique. The result shows most decline in systolic and diastolic BP was at KC group which got a high AGEs diet and moderate intensity exercise. KC’s systolic BP was measured 120 ± 2.82 mmHg and diastolic at 77.25 ± 9.5 mmHg. The results of ELISA examination show KN has higher sRAGE level at 1865 ± 503.4 ng/L on the contrary KP has lower sRAGE level at 530 ± 78.6 ng/L.
Pengaruh Latihan Running With The ball terhadap Peningkatan Keterampilan Dribbling Pemain Sepak Bola Usia 13-15 Tahun di Sekolah Sepak Bola (SSB) SINGOJOYO Kabupaten Malang Moch. Maulidan; Supriyadi Supriyadi; Ardhiyanti Puspita Ratna
Pendekar : Jurnal Pendidikan Berkarakter Vol 2 No 2 (2024): April : Jurnal Pendidikan Berkarakter
Publisher : LPPM Politeknik Pratama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51903/pendekar.v2i2.669

Abstract

It can be seen that this study has one goal, namely to determine the effeck of running with the ball exercise on improving the dribbling skill of SBB Singojoyo football players, Malang Regency. This study used a sample off all 13-15 years old SSB Singojoyo soccer athletes in Malang, totaling 20 people using a sampling technique. In this study, the experimental method was applied, with the One-Group Pretest-Postest experimental design. The instrument used is the Test Course of the Sport Dribbling test which is used during the pretest dan posttest. The results of this study used the normality test and paired sample t test, which showed that there was a significant effect on improving dribbling skills by giving running with the ball exercises. This can be seen by looking at the results of data analysis on the calculation of the t test which shows that t count is greater than t table (4,162>2,093) with a significance test (∝) = 0.05 and a total sample (N = 20), the hypothesis is accepted and has an effect. Based on the results of the study it can be concluded that running with the ball exercise has a significant influence of tge dribbling skills of SSB Singojoyo Malang Regency aged 13-15 years.
Perubahan Tingkat Pengetahuan dan Sikap Santri Husada Sebagai Peer Educator Promosi Kesehatan Reproduksi Ardhiyanti Puspita Ratna; Taurisma Aulia Nanda Wibisono; Zhafirah Auliarahma; Hilma Tsurayya Iftihurozza; Zumroh Hasanah; Tisnalia Merdya Andyastanti
COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat Vol. 4 No. 7 (2024): COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/comserva.v4i7.2608

Abstract

Masa remaja adalah masa transisi dari anak-anak menuju dewasa. Pada masa ini ditandai dengan adanya perubahan kognitif dan adanya kematangan seksual seperti hormonal. Remaja memerlukan pemahaman tentang kesehatan reproduksi agar dapat menjaga kesehatan secara optimal, menghindari risiko penyakit menular seksual, serta membuat keputusan yang tepat terkait kehidupan reproduksi di masa depan. Pesantren adalah salah satu lembaga pendidikan di Indonesia yang menaungi pendidikan remaja yaitu para santrinya. Berdasarkan Focused Group Discussion yang diadakan dengan santri husada PP Nurul Ulum Putri Kota Malang diketahui pemahaman tentang kesehatan reproduksi masih kurang. Tim Pengabdian FK UM melakukan kegiatan pelatihan dan pendampingan kepada santri husada untuk meningkatkan peran mereka sebagai peer educator kesehatan reproduksi dengan melakukan pelatihan berbasis studi kasus. Kegiatan melibatkan 60 orang santri dan berlangsung selama 3 bulan. Dari hasil pelatihan didapatkan pengetahuan santri Husada meningkat dari rata-rata 58.75±14.9 sebelum pelatihan menjadi 82.9±10.86 setelah pelatihan, hasil uji paired T menunjukkan signifikasi 0,000. Selain itu, setelah pelatihan, santri Husada menunjukkan perilaku mendukung promosi kesehatan reproduksi di pesantren sebanyak 63%, perilaku sangat mendukung sebesar 30%, dan perilaku tidak mendukung hanya 7%. Dapat disimpulkan pelatihan dan pendampingan berbasis studi kasus dapat meningkatkan pengetahuan dan mengubah sikap santri husada dalam promosi kesehatan reproduksi.