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All Journal Sari Pediatri Biomedical Journal of Indonesia Paediatrica Indonesiana Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal 'Aisyiyah Medika Journal of Industrial Engineering
Afifa Ramadanti
Department Of Child Health, Universitas Sriwijaya Medical School/Dr. Moh. Hoesin General Hospital, Palembang, South Sumatra, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health

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Comparison between Leukocyte Esterase Activity (LEA) and Histopathology Examination in Identifying Chorioamnionitis Cases: Uji Diagnostik Leukocyte Esterase Activity (LEA) terhadap Histopatologi pada Kasus korioamnionitis Putri H Novianesari; Nuswil Bernolian; Henni Maulani; Afifa Ramadanti; Theodorus Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 7, No. 1 January 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (72.754 KB) | DOI: 10.32771/inajog.v7i1.823

Abstract

Objective: To compare sensitivity and specificity of LEA to histopathology examination in diagnosing chorioamnionitis. Methods: We compared diagnostic tests in dr. Mohammad Hoesin hospital, Palembang, from September 2015 to April 2016. Ninety-one pregnant women were included. LEA and histopathology examination were carried out with neonatal sepsis as main outcome. Data were analysed by SPSS version 21.0 and Med-calc statistic. Results: Chorioamnionitis was detected in 54 (77.1%) patients with gestational period ≥37 weeks and in 16 (22.9%) patients with gestational period <37 weeks. Duration of membrane rupture was significantly associated with chorioamnionitis (p = 0.001 and p = 0.011). Neonatal sepsis was also significantly associated with chorioamnionitis in both groups (p = 0.014 and p = 0.036). LEA value with cut-off point >0.5 was able to significantly predict chorioamnionitis with 98.6% sensitivity and 95.2% specificity, providing better accuracy in diagnosing chorioamnionitis in preterm pregnancy group. Conclusion: LEA had a very good predictive value for chorioamnionitis with better accuracy in diagnosing chorioamnionitis in preterm pregnancy. Keywords: Chorioamnionitis, Histopathology, Leukocyte esterase activity, Neonatal sepsis, Salafia criteria Tujuan: Membandingkan sensitifitas dan spesifisitas diagnosis korioamnionitis antara pemeriksaan Leukocyte esterase activity (LEA) terhadap histopatologi. Metode: Penelitian uji diagnostik dilakukan di RSUP dr. Mohammad Hoesin Palembang selama periode September 2015 – April 2016, 91 wanita hamil yang memenuhi kriteria inklusi selanjutnya dilakukan pemeriksaan LEA, Histopatologi dan luaran sepsis neonatorum. Data kemudian dianalisis dengan menggunakan software SPSS versi 21.0 dan Med-calc statistic. Hasil: Korioamnionitis terdeteksi pada 54 (77,1%) pasien dengan usia gestasi ≥37 minggu dan 16 (22,9%) pada usia gestasi <37 minggu. Durasi lamanya pecah ketuban akan berpengaruh secara signifikan terhadap kejadian korioamnionitis (p = 0,001 dan p = 0,011), Sepsis neonatorum juga secara signifikan berhubungan dengan kejadian korioamnionitis pada kedua kelompok (p = 0,014 dan p = 0,036). Kadar LEA dengan cut off point >0,5 secara signifikan mampu memprediksi kejadian korioamnionitis dengan sensitivitas 98,6%, spesifisitas 95,2% dan nilai akurasi yang lebih baik ditemukan dalam penegakan diagnosis korioamnionitis pada kelompok kehamilan preterm. Kesimpulan: Pemeriksaan LEA memiliki kekuatan prediksi yang sangat baik terhadap kejadian korioamnionitis dengan akurasi yang lebih baik dalam mendiagnosis korioamnionitis pada kehamilan preterm. Kata kunci: Korioamnionitis, Histopatologi, Leukocyte Esterase Activity,Sepsis Neonatorum, Kriteria Salafia
Analisis Risiko Kesehatan Dan Keselamatan Kerja Di Pabrik Tempe Bapak Carmin Dengan Menggunakan Metode Hazard And Operability Study (HAZOP) Santika Sari Sari; Afifah Wahyu Ramadanti; Mariana Audini
JIE Scientific Journal on Research and Application of Industrial System Vol 7, No 1 (2022)
Publisher : President University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33021/jie.v7i1.3370

Abstract

Hazard and Operability (HAZOP) approach is one of a qualitative methodology risk analysis that is often used for identified the potential danger in the workplace. This research was conducted directly at Carmin’s Tempe Factory by interviewing the workers. Steps in this research are sorting the production process, identified the potential of danger by worksheet hazop, analyzing risk control, monitoring and evaluation, designing improvements, and drawing conclusions. The results showed that there were 18 potential hazards in 8 stages of the tempe-making process at Carmin's factory. Some improvements are needed,  such as equalization of operators for each work station, improvement of workspaces, and the addition of ergonomic tools so that the potential for accidents can be controlled
Medical and non-medical factors associated with stunting in infants and toddlers aged 3-59 months in Palembang Elsi, Yuanita Rimadini; Fauzi, Moretta Damayanti; Anzar, Julius; Indra, Raden Muhammad; Yosy, Deny Salverra; Saputra, Indra; Ramadanti, Afifa
Paediatrica Indonesiana Vol. 65 No. 1 (2025): January 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.1.2025.16-24

Abstract

Background Although the prevalence of stunting in South Sumatera is estimated to be relatively high, there have been few studies to date on stunting and the factors associated with it in the region. Objective To determine the proportion of stunting in infants and toddlers aged 3-59 months at Mohammad Hoesin General Hospital (RSMH), Palembang, South Sumatera, and to identify medical and non-medical factors associated with stunting in these children. Methods A cross-sectional study was conducted at RSMH from April to September 2023. Stunting was defined according to the WHO standard and combined with a growth pattern that reflects chronic malnutrition. We recorded the proportion of stunting as well as data on several potential medical and non-medical risk factors of stunting. Results A total of 183 subjects met the inclusion criteria. The overall proportion of stunting was 65/183 (35.5%). The proportion of stunting was higher in boys (39.6%) and in children <2 years of age (38.2%). Medical risk factors significantly associated with stunting were infectious disease [OR 4.13 (95%CI 1.91 to 8.94); P=0.001] and chronic disease [OR 3.02 (95%CI 1.56 to 5.85); P=0.001]. The only non-medical factor significantly associated with stunting was low paternal education level [OR 2.45 (95%CI 1.17 to 5.15); P=0.016]. Conclusion During the study period, over a third of pediatric patients at RSMH experienced stunting. Infectious disease, chronic disease, and low paternal education level were significant risk factors that contributed to the occurrence of stunting.
Factors Affecting Breastfeeding Practice among Mothers with Hospitalized Neonates Lestari, Peby Maulina; Ramadanti, Afifa; Latifah, Murwani Emasrissa; Sutrisno, Muhammad Al Farisi; Andrina, Hana; Stevanny, Bella
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 1 Maret 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i1.707

Abstract

Introduction: Breastfeeding is essential for premature infants, as it reduces morbidity while enhancing cognitive development, ultimately supporting a more productive adulthood. However, in the United States, where 10–12% of infants are born prematurely, hospitalization in the Neonatal Intensive Care Unit (NICU) presents significant challenges to breastfeeding practices as it introduces barriers such as maternal stress, mother-infant separation, limited visitation, and inadequate support, which hinder successful breastfeeding. Method: This review used several databases, namely Google Scholar, Science Direct, Elsevier, Medline, PubMed, Proquest, dan Wiley Online Library to search original and review articles in English about breasfeeding, internsive care unit, and risk factors in the last 10 years. Other reference sources used were guidelines and textbooks.Result: The findings reveal that breast milk’s bioactive components play a critical role in protecting against morbidity during NICU hospitalization, while also fostering cognitive development. Factors influencing breastfeeding practices include demographic (maternal age, education), biological (maternal and infant health), attitudinal (breastfeeding confidence), social (family support), and hospital regulations (NICU policies).Conclusion: Factors affecting breastfeeding practice among mothers with hospitalized neonates include planned pregnancy, medical interventions, and family support. NICU hospitalization can be a significant barrier to breastfeeding due to inadequate support, visitation time, mother-infant separation, maternal stress and anxiety, and clinical conditions.Faktor-Faktor yang Memengaruhi Praktik Menyusui pada Ibu dengan Neonatus Rawat InapAbstrakPendahuluan: Pemberian Air Susu Ibu (ASI) sangat penting bagi bayi prematur karena dapat mengurangi morbiditas sekaligus meningkatkan perkembangan kognitif, yang pada akhirnya mendukung kehidupan dewasa yang lebih produktif. Namun, di Amerika Serikat, di mana 10–12% bayi lahir prematur, rawat inap di Neonatal Intensive Care Unit (NICU) menghadirkan tantangan signifikan terhadap praktik menyusui akibat berbagai hambatan seperti stres maternal, pemisahan ibu dan bayi, waktu kunjungan yang terbatas, serta dukungan yang tidak memadai, yang menghalangi keberhasilan menyusui.Metode: Tinjauan pustaka ini menggunakan beberapa basis data, yaitu Google Scholar, Science Direct, Elsevier, Medline, PubMed, Proquest, dan Wiley Online Library, untuk mencari artikel asli dan ulasan dalam bahasa Inggris tentang menyusui, unit perawatan intensif, dan faktor risiko dalam 10 tahun terakhir. Sumber referensi lainnya yang digunakan adalah pedoman dan buku teks.Hasil: Kumpulan bukti yang ada di literatur saat ini menunjukkan bahwa komponen bioaktif dalam ASI memiliki peran penting dalam melindungi bayi dari morbiditas selama hospitalisasi di NICU, sekaligus mendukung perkembangan kognitif. Faktor-faktor yang memengaruhi praktik menyusui meliputi faktor demografis (usia ibu, pendidikan), biologis (kesehatan ibu dan bayi), sikap (kepercayaan diri dalam menyusui), sosial (dukungan keluarga), dan kebijakan rumah sakit (aturan di NICU).Kesimpulan: Faktor-faktor yang memengaruhi praktik menyusui pada ibu dengan bayi yang dirawat di NICU meliputi kehamilan yang direncanakan, intervensi medis, dan dukungan keluarga. Rawat inap di NICU dapat menjadi penghalang signifikan terhadap keberhasilan menyusui akibat kurangnya dukungan, waktu kunjungan yang terbatas, pemisahan ibu dan bayi, stres dan kecemasan maternal, serta kondisi klinis bayi.Kata Kunci: Air susu ibu, Faktor risiko, Ibu, Menyusui, NICU
Hemodynamically significant patent ductus arteriosus and tissue oxygenation in preterm infants Amaliah, Lissaberti; Indrayady, Indrayady; Ramadanti, Afifa; Nova, Ria; Akbari, Atika
Paediatrica Indonesiana Vol. 65 No. 5 (2025): September 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.5.2025.364-72

Abstract

Background  One of the most common side effects of preterm birth is hemodynamically significant patent ductus arteriosus (hsPDA), with a prevalence of approximately 70% among preterm infants. The clinical consequences of hsPDA are impaired tissue perfusion and oxygenation to organs. Near-infrared spectroscopy (NIRS), a validated non-invasive method for determining regional oxygen saturation (rSO2), can identify early changes in organ perfusion and oxygenation.  Cerebral and renal tissues as these vital organs are highly susceptible to systemic hypoperfusion caused by hsPDA, which can lead to serious complications such as brain injury and renal insufficiency.  We used (NIRS to clarify the impact of hsPDA on regional oxygenation in the brains and kidneys of preterm infants. Objective To compare oxygenation of cerebral and renal regional tissues in preterm infants with and without hsPDA Methods A cross-sectional study was conducted at Mohammad Hoesin Hospital. Forty preterm infants (gestational age <37 weeks), born between November 2023 and September 2024, who were diagnosed with PDA and had a chronological age >24 hours and <7 days, were enrolled. Infants with multiple congenital anomalies, ductal-dependent cyanotic congenital heart disease, early-onset sepsis, or without parental consent were excluded. Cerebral and renal oxygenation were assessed using NIRS monitoring. Statistical analysis was performed with unpaired T-test. Results Based on echocardiographic criteria, 22 of the 40 infants had hsPDA, while 18 had non-hsPDA. The mean cerebral rSO2 values in the hsPDA and non-hsPDA groups were 79.5 (SD 12.1)% and 80.9 (SD 4.3)%, respectively. The mean renal rSO2 values were 70.4 (SD 17.8)% and 77.8 (SD 6.4)%, respectively. The mean cerebral fractional tissue oxygen extraction (FTOE) values of the hspda and non-hsPDA groups were 0.2 (0.1 to 0.21). The mean renal FTOE values were 0.3 (SD 0.19) and 0.2 (SD 0.07), respectively. There were no significant differences between the two groups in renal and cerebral rSO2 and FTOE. Conclusion Preterm infants’ cerebral and renal tissue oxygenation is  were not significantly different in those with and without hsPDA.  
Co-Authors Achirul Bakri Ading Rohadi Akbari, Atika AMALIAH, LISSABERTI Andrina, Hana Deny Salverra Yosy, Deny Salverra Diah Sukarni Elsi, Yuanita Rimadini Erial Bahar ERMA PUSPITA SARI Fauzi, Moretta Damayanti Henni Maulani Herka Pratama Putra Herman Bermawi Hertanti Indah Lestari Hertanti Indah Lestari, Hertanti Indah Iman Hendarman Indra Saputra Indra, Raden Muhammad Indrayady Indrayady Indrayady, Indrayady Julius Anzar, Julius Latifah, Murwani Emasrissa Lumbantoruan, Regina Paranggian Mariana Audini Maulani, Henni Nessie Amelia Ramli Novianesari, Putri H Nuswil Bernolian Peby Maulina Lestari, Peby Maulina Putri H Novianesari Raden Muhammad Indra Regina Paranggian Lumbantoruan Renya Hiasinta Ria Nova, Ria Santika Sari Stevanny, Bella Sutrisno, Muhammad Al Farisi Teti Hendrayanti Theodorus Theodorus Theodorus Theodorus Widia Wati Yuli Doris Memy Yulia Iriani, Yulia