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All Journal PROSIDING SEMINAR KIMIA JURNAL INDRIA (Jurnal Ilmiah Pendidikan Prasekolah dan Sekolah Awal) JURNAL ATOMIK
Winni Astuti, Winni
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Energy Environmental Science

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AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN TANAMAN SAMBUNG URAT (Cayratia carnosa) TERHADAP Salmonella thypi and Propionibacterium acnes Inna, Mutma; Astuti, Winni; Saleh, Chairul
JURNAL ATOMIK Vol 7 No 1 (2022)
Publisher : Jurusan Kimia FMIPA UNMUL

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This research was conducted to the content of secondary metabolite of methanol extract of Cayratia carnosa leaf and activity toward Salmonella thypi and Propionibacterium acnes. The phytochemical test has tested by color testing and antibacterial activity carried out by agar diffution method. The secondary metabolites contained in the methanol extract from the Cayratia carnosa leaf are Flavonoids, Steroid and phenolic. Methanol extract from Cayratia carnosa leaf has a wide range of action. The value of Minimun Inhibitory Concentracion (MIC) for methanol extracts from the Cayratia carnosa leaf toward Salmonella thypi is between 6 to 8% and Propionibacterium acnes between 0.5 to 1%. Keywords: Cayratia carnosa (Link) Gagnepain, Phytochemical test, Antibacterial activity.
TEST OF AMYLASE INHIBITION ACTIVITY OF Melicope PLANTS WHICH POTENTIAL AS ANTIDIABETIC AGENTS Nurjanah, Siti; Marliana, Eva; Astuti, Winni
JURNAL ATOMIK Vol 5 No 2 (2020)
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The test of amylase inhibition activity of the leaves of Melicope lunu-ankenda and bark of Melicope glabra (BI.) T.G. Hartley extracts were done. The objective of this study was to determine in-vitro α-amylase inhibition activity against two samples by DNS method. The result showed that two samples of Melicope lunu-ankenda leaves and bark of Melicope glabra (BI.) TG Hartley displayed the enzyme inhibitory effect with percent inhibitions of 48.71% and 46.36%. Two sample extracts can inhibit amylase. It can be suggested that about sample were potential as antidiabetic agents.
ENDOPHYTIC BACTERIA SCREENING FROM THE LEAVES OF OKRA (Abelmoschus esculentus L. Moench) WHICH PRODUCED LIPASE Utami, Nanda Putri; Astuti, Winni; Kartika, Rudi
JURNAL ATOMIK Vol 5 No 2 (2020)
Publisher : Jurusan Kimia FMIPA UNMUL

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Endophytic bacteria found in plant tissues can produce enzymes, one of which is lipase. The purpose of this study was to screening endophytic bacteria from the leaves of Okra (Abelmoschus esculentus L. Moench) which produced lipases. The method used in this study is screening with media nutrient agar (NA) containing Rhodamine B and olive oil. The results showed that 4 of bacterial isolates (D1, D2, D3 and D4) from 14 endophytic bacterial isolates had lipase activity. The crude lipase extract was quantitatively tested for lipase activity by the titrimetry method. The highest lipase activity was shown by isolates with a D1 code of 1.50 U/mL.
RESPON TRAKEOSPASMOLITIK EKSTRAK METANOL DAUN Macaranga lamellata Whitmore SECARA IN VITRO Afandi, Irvan; Astuti, Winni; Marliana, Eva
JURNAL ATOMIK Vol 7 No 1 (2022)
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The research about in vitro trakeospasmolytic response of methanol extract of Macaranga lamellata Whitmore leaves was carried out. This research was conducted to determine the spasmolytic effect of the methanol extract of Macaranga lamellata Whitmore leaves on changes in separate organ of the guinea pig ring tracheal. The methods used include the bioassay isolated organ with two groups of treatment, control group and extract group. Methanol extract was given cumulatively on the organ bath. Positive control is used aminofilin and negative control is used DMSO solvent. Phytochemical test results showed that total methanol extract contained alkaloids, polyphenol, steroids, flavonoids dan saponins while phytochemical test results showed on ethyl acetate fraction contained alkaloids, polyphenol, steroids, quinons dan flavonoids. The Percentage change in tracheal smooth muscle as a spasmolytic response by using methanol extract with cumulative concentration of 0.3, 1 dan 3 mg/mL respectively -24.925%; -29.865% and -36.795% . This research is shown methanol extract of Macaranga lamellata Whitmore leaves have antiasthma effect based on the tracheospasmolytic activity. Keywords: Antiasthma, Bioassay isolated organ, Macaranga lamellata Whitmore, Marmot, Trakeopasmolytic.
Daya Antibakteri Ekstrak Metanol Buah Okra (Abelmoschus esculentus (L.) Moench) puah, Siti Mar; Astuti, Winni; Hindryawati, Noor
JURNAL ATOMIK Vol 6 No 2 (2021)
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ABSTRACT Phytochemical test and antibacterial activity of methanol extract of Okra (Abelmoschus esculentus (L.) Moench) fruit have been carried out. Extraction using maceration method. The methanol extract of Okra fruit contains phenolic secondary metabolites, alkaloids and steroids. Antibacterial activity opposes the agar diffusion method against the bacteria Salmonella typhi and Steprococcus mutans. The Minimum Inhibitory Concentration Value of Okra fruit methanol extract against Salmonella typhi bacteria at a concentration of 0.625-1.25% and against Streptococcus mutans bacteria 1.25% -2.5%. Okra fruit methanol extract has antibacterial activity with wide variations. Keywords : Abelmoschus esculentus (L.) Moench, antibacterial activity, secondary metabolites, Minimum Inhibitory Concentration (MIC).
Daya Antibakteri Extrak Metanol Batang Melicope glabra (BI.) T.G. Hartley Purnamasari, Ade Rezki; Astuti, Winni; Marliana, Eva
JURNAL ATOMIK Vol 7 No 1 (2022)
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ABSTRAK Uji fitokimia dan uji aktivitas antibakteri ekstrak metanol batang Melicope glabra (BI.) T.G. Hartley telah dilakukan. Ektraksi sampel batang Melicope glabra dilakukan dengan metode maserasi menggunakan pelarut metanol. Uji aktivitas antibakteri dilakukan menggunakan metode difusi agar. Hasil uji fitokimia menunjukkan ekstrak metanol batang Melicope glabra mengandung senyawa metabolit sekunder flavonoid, fenolik, triterpenoid dan steroid. Nilai MIC (Minimum Inhibitory Concentration) ekstrak metanol batang Melicope glabra (BI.) T.G. Hartley untuk bakteri Salmonella typhi adalah pada konsentrasi 1,25%, sedangkan untuk bakteri Staphylococcus aureus adalah pada konsentrasi 2,5%. Ekstrak metanol batang Melicope glabra (BI.) T.G. Hartley memiliki aktivitas antibakteri dengan spektrum luas. Kata Kunci : Melicope glabra (BI.) T.G. Hartley, aktivitas antibakteri, metabolit sekunder
SCREENING OF LIPASE FROM WATER BACTERIA IN BENANGA LEMPAKE DAM, NORTH SAMARINDA AND ITS POTENTIAL AS A DETERGENT ADDITIVE Vera, Hendrica Mini; Astuti, Winni; Pratiwi, Djihan Ryn
JURNAL ATOMIK Vol 8 No 2 (2023)
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Lipase is an enzyme that can hydrolyze triglycerol into glycerol and free fatty acids. The aim of this research is to obtain lipase-producing bacteria and determine the potential of lipase from water bacteria in the water of the Benanga Lempake Dam, North Samarinda for biodetergent applications through stability test of lipase activity against several commercial detergents. Screening of lipase-producing bacteria was carried out on nutrient agar media containing olive oil and Rhodamine B. The results showed that seven isolates were capable of producing lipase. Based on the stability test of lipase on detergent, it can be seen that the activity of lipase decreased by more than 70% at the addition of 1% detergent.
UJI FITOKIMIA DAN ANTIBAKTERI EKSTRAK ETANOL BIJI MAHONI (Swietenia mahagoni (L.) Jacq) Arwidhiah, Nanda; Saleh, Chairul; Astuti, Winni
JURNAL ATOMIK Vol 6 No 2 (2021)
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Phytochemical test and antibacterial activity of ethanol extract of Mahoni seed (Swietenia mahagoni (L.) Jacq) have been done. The extraction of Mahoni seed samples was carried out by the maceration method using ethanol as a solvent. An antibacterial activity test was carried out using the agar diffusion method. Phytochemical tests results show that ethanol extract of Mahoni seeds has secondary metabolites of alkaloid, triterpenoid, and phenolic compounds. The antibacterial activity test results obtained MIC values for Streptococcus mutans bacteria were 1.25-2.5% and for Salmonella typhi bacteria at 0.625-1.25%. Ethanol extract of Mahoni seeds has broad-spectrum antibacterial activity.
RESPON VASODILATASI EKSTRAK METANOL DAUN Macaranga lamellata Whitmore SECARA IN VITRO Amalia, Elfiza; Astuti, Winni; Marliana, Eva
JURNAL ATOMIK Vol 6 No 2 (2021)
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The research about in vitro vasodilatation response of methanol extract of Macaranga lamellata whitmore leaves was carried out. This research was conducted to determine the vasodilatation response of methanol extract of Macaranga lamellata Whitmore leaves on changes in aortic tone of Wistar rat. The methods used include the in vitro methods by using separated aortic organ of Wistar rat. Methanol extract were given cumulatively in bath organs. Positive control is used methacholine and negative control is used DMSO solvent. T-test statistical was done to determine the significant differences between groups. Phytochemical test results showed that total methanol extract contained alkaloids, polyphenol, steroids, flavonoids and saponins. Percentage change in aortic tone by using methanol extract concentration of 0.3; 1 and 3 mg/mL respectively were -7.422%; -9.641% and -10.593%. Methanol extract of Macaranga lamellata Whitmore leaves have antihypertensive potential. Keywords: Antihypertensive, Aortic, In vitro, Macaranga lamellata Whitmore, Vasodilatation
AKTIVITAS AMILASE PENDEGRADASI PATI MENTAH DARI BAKTERI TANAH TEMPAT PEMBUANGAN AKHIR BUKIT PINANG Putri, Amanda Aulia; Astuti, Winni; Pratiwi, Djihan Ryn
JURNAL ATOMIK Vol 9 No 2 (2024)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ja.v9i2.1408

Abstract

Raw starch-degrading amylase (RSDA) is a hydrolytic enzyme that can degrade raw starch into glucose. This study was conducted to obtain raw starch-degrading amylase-producing bacteria from the soil of the Bukit Pinang Landfill, Samarinda City. Isolation of bacteria using the spread plate method. Screening of RSDA-producing bacteria using nutrient media to contain raw starch. Isolation of bacteria obtained 10 single colonies of bacteria. The isolated bacteria were selected for their ability to produce RSDA. All single colonies of bacteria could produce RSDA and their activity was tested quantitatively using the 3,5 Dinitrosalicylic Acid (DNS) method. Bacteria with the TPA 1 colony code had the highest activity of 3.837 U/mL.
Co-Authors A. A. R, Muhammad Taufik Admaja, Junior Try Afandi, Irvan Ahmad Suryadi, Ahmad Alawiyah, Dessy Noor Amalia, Elfiza Anggriani, Yusnia Wati Aristina, Reza Fauziah Arwidhiah, Nanda Az-zahra, Deannisa Khoiru Chairul Saleh Djihan Ryn Pratiwi, Djihan Ryn Erwin Erwin Eva Marliana, Eva Fahmi, Ismi Haeruddin Haeruddin Hairani, Rita Kesuma, Yonanda Meisya Kusumawardani, Niken Marliani, Nelly Mikdariawan, Adha Mutma Inna Nasution, Safridah Hannum Noor Hindryawati, Noor Nur, Istianti Irfa'a Nursanti, Oktavia Widya Panuti, Putri Rahayuning puah, Siti Mar Purnamasari, Ade Rezki Putri, Amanda Aulia Rabiatul Adawiyah Rahimah, Priliza Rahmaniah, Rahmaniah Rakasiwi, Dea Rudi Kartika, Rudi Ruga, Ritbey Saibun Sitorus Salsabila, Ervina Shafarini, Eno Julia Siti Nurjanah Sya'bani, Nurillah Trisnawati, Eka Elly Usdin, Muhammad Sadam Utami, Nanda Putri Vera, Hendrica Mini Wahyu Pratama