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All Journal PROSIDING SEMINAR KIMIA Jurnal Kimia Mulawarman Science and Technology Indonesia JURNAL ATOMIK PRIMER: Jurnal Ilmiah Multidisiplin al Kimiya : Jurnal Ilmu Kimia dan Terapan Journal of Science and Technology: Alpha
Djihan Ryn Pratiwi, Djihan Ryn
Jurusan Kimia FMIPA Universitas Mulawarman
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Energy Environmental Science Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Physics Social Sciences

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UJI FITOKIMIA DAN UJI TOKSISITAS EKSTRAK KASAR DAUN, BATANG DAN KULIT BATANG TANAMAN AFRIKA (Vernonia amygdalina Del.) Indah Ashari Rahmadani; Erwin Erwin; Djihan Ryn Pratiwi
PROSIDING SEMINAR KIMIA 2021: SEMINAR NASIONAL KIMIA 2021
Publisher : PROSIDING SEMINAR KIMIA

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Abstract

Tanaman afrika (Vernonia amygdalina Del.) merupakan salah satu tanaman obat yang banyak dimanfaatkan oleh masyarakat. Tujuan penelitian ini yaitu untuk menentukan kandungan senyawa metabolit sekunder yang terdapat dalam ekstrak kasar daun, batang dan kulit batang tanaman Afrika (Vernonia amygdalina Del.) serta menentukan tingkat toksisitas (menentukan nilai LC50 dari ketiga ekstrak kasar tersebut) menggunakan metode BSLT (Brine Shrimp Lethality Test). Hasil yang diperoleh dari penelitian ini yaitu metabolit sekunder yang terkandung pada ekstrak kasar daun afrika yaitu flavonoid, triterpenoid dan steroid, pada ekstrak kasar batang tanaman afrika yaitu alkaloid, flavonoid dan steroid serta pada ekstrak kasar kulit batang tanaman afrika yaitu alkaloid, flavonoid, fenolik, triterpenoid dan steroid. Nilai LC50 ekstrak kasar daun, batang dan kulit batang tanaman afrika sebesar 399,85 ppm; 118,25 ppm dan 80,82 ppm, secara berturut-turut. Ketiga jenis ekstrak ini bersifat toksik (LC50 < 1000 ppm). Kata kunci: Tanaman afrika, fitokimia, toksisitas
THE EFFECT OF MACKEREL (Scomberomorus commerson) IN THE FEED TO THE DECLINE IN BLOOD CHOLESTEROL LEVEL HYPERCHOLESTEROLEMIC MALE MICE (Mus musculus) Rudi Kartika; Djihan Ryn Pratiwi; Arifwan -; Wahyu Budi Utama; Wahyu Teguh Santoso
PROSIDING SEMINAR KIMIA SEMINAR NASIONAL KIMIA 2014
Publisher : PROSIDING SEMINAR KIMIA

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Abstract

Blood cholesterol levels wh ich were higher than normal is trigger of various diseases. The objective of the research was to know “The Effect of Mackerel (Scomberomorus co mmerson) in the Feed to the Decline in Blood Cholesterol Levels in Hypercholesterolemic Male Mice (Mus musculus). The study was conducted over 40 days using completely randomized design with treatments, the positive control, negative control, and the mice were given the addition of mackerel on a standard feed with 3 different levels so grouped in L1 (2:1); L2 (1:1) and L3 (1:2). The parameters measured are total cholesterol blood serum of mice with the CHOD-PAP method. Cholesterol levels are measured with a photometer 5010 at a wavelength of 500 nm. The result in the (-) 86 mg/d L; (+) 113 mg/d L; L1 102 mg/d L; L2 86 mg/dL; and L3 82 mg/dL.
STUDI POTENSI SENYAWA DERIVATIF FLAVONOID DARI TANAMAN GENUS MACARANGA TERHADAP PROTEIN E6 HPV DENGAN METODE DOCKING MOLECULAR Veliyana Londong Allo; Djihan Ryn Pratiwi
JURNAL KIMIA MULAWARMAN Vol 16 No 2 (2019)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v16i2.1006

Abstract

Interaction study of active compounds of a medicinal plant with cervical cancer cells using the Docking Molecular (In Silico) method. In this research design the active compound sophoraflavanone B, 5,7,3 ', 4'-tetrahidroxy-3,6-diprenylflavone, apigenin and quercetin are first calculated using a quantum approach based on SCF method set 3-21G to obtain a stable compound form and has the lowest energy. Stable compounds interact with cervical cancer cells obtained from protein bank data (GDP) that have been prepared previously to obtain an inhibitory energy value, the number of hydrogen bonds and other factors that influence a Docking Molecular calculation. The interaction of compounds 5,7,3 ', 4'-tetrahydroxy-3,6-diprenylflavone against E6-HPV of 4 hydrogen bonds with a distance of 2.7-3.23 Å.
SKRINING FITOKIMIA DAN UJI TOKSISITAS EKSTRAK KASAR, FRAKSI N-HEKSANA, ETIL ASETAT, DAN METANOL-AIR DAUN KIRINYUH (Chromolaena odorata (L.) King & H.E Robins) Tri Riski Amalia; Djihan Ryn Pratiwi; Erwin Erwin
PROSIDING SEMINAR KIMIA Vol 1 No 1 (2022): Prosiding SNK 2022
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Kirinyuh leaves (Chromolaena odorata (L.) King & H.E Robins) is one of the plants of the Asteraceae family that is commonly used by the community as a wound healing medicinal ingredient and has antioxidant and antibacterial activities. This research was conducted to determine the type of secondary metabolite compounds contained in the crude extract, n-Hexane, ethyl acetate and methanol-water fraction kirinyuh leaves (Chromolaena odorata (L.) King & H.E Robins) and determine the level of toxicity against to Artemia salina L. using the BSLT method. Phytochemical test results of crude extract leaves kirinyuh (Chromolaena odorata (L.) King & H.E Robins) contain alkaloids, flavonoids, steroids, and phenolics. The n-Hexane fraction contains steroids and quinones. The ethyl acetate fraction contains flavonoids and phenolics. The methanol-water fraction contains flavonoids, saponins and phenolics. Based on toxicity tests, crude extract, n-hexane, ethyl acetate fractions of kirinyuh leaves is highly toxic with successive LC50 values of 2.88 ppm, 8.12 ppm and 6.86 ppm, then the methanol-water fraction is toxic with an LC50 value of 186.76 ppm. Keywords: Kirinyuh leaves, phytochemicals, toxicity
REVIEW JURNAL: POTENSI DAUN NIPAH DALAM OBAT TRADISIONAL SEBAGAI AKTIVITAS ANTIINFLAMASI Angellina Putri Petrisia; Chairul Saleh; Djihan Ryn Pratiwi
PROSIDING SEMINAR KIMIA Vol 1 No 2 (2023): Prosiding SNKT II 2022
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Nipah (Nypa fruticans Wurmb) is a mangrove plant from the Palmae tribe that grows along rivers that are affected by tides. The abundance of nipa palm in mangrove forests is quite high, so it has great potential to be developed. This review aims to discuss the potential anti-inflammatory activity of nipah leaves as traditional medicine, so that they can add value to nipah leaves and can be useful in the health sector. The literature search was carried out through Google Scholar and Scholar research papers related to the ability of anti-inflammatory activity in nipah leaves and other Arecaceae families. Nipah leaf extract contains secondary metabolites, namely flavonoids, phenolics, tannins, steroid saponins and triterpenoids. Flavonoids can function as inhibitors of cyclooxygenase and lipoxygenase enzymes so that they can be used to treat anti-inflammatory. Based on the literature, it can be concluded that nipah leaves are potentially effective as traditional medicine in treating inflammation or inflammation. Keywords: Nipah (Nypa fruticans Wurmb), anti-inflammatory and flavonoids
AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN KENITU (Chrysophyllum cainito L.) TERHADAP Salmonella thypi ATCC 422 Ade Dinaran; Chairul Saleh; Djihan Ryn Pratiwi
PROSIDING SEMINAR KIMIA Vol 1 No 2 (2023): Prosiding SNKT II 2022
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Kenitu (Chrysophyllum cainito L.) is one of the plants that has the potential to cure fever, diarrhea and inflammation of the respiratory tract. This study aimed to determine the minimum inhibitory concentration value of kenitu leaf methanol extract (Chrysophyllum cainito L.) against Salmonella thypi bacteria ATCC 422. The minimum inhibitory concentration value of kenitu (Chrysophyllum cainito L.) against Salmonella thypi ATCC 422 bacteria was 0.625 %. The presence of antibacterial activity of kenitu leaf methanol extract (Chrysophyllum cainito L.) contains secondary metabolite compounds of alkaloid, phenolic and steroid groups. Keywords: Chrysophyllum cainito L., antibacterial, minimum inhibitory concentration, Salmonella thypi ATCC 422
UJI AKTIVITAS ANTIINFLAMASI DARI EKSTRAK METANOL DAUN KENITU (Chrysopyllum cainito L.) SECARA IN VITRO Nur Hidayah; Chairul Saleh; Djihan Ryn Pratiwi
PROSIDING SEMINAR KIMIA Vol 1 No 2 (2023): Prosiding SNKT II 2022
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Antiinflammatory activity tests of extract and fractions of kenitu Leaves (Chrysopyllum cainito L) in vitro were carried out. This research aimed to determine the anti-inflammatory activity of crude extract methanol of kenitu leave with protein denaturation inhibition method by using BSA (Bovine serum albumin). Diclofenac sodium was used as positive control and the negative control used the appropriate solvent. Based on phytochemical screening test, methanol extracts are known to contain secondary metabolites including flavonoids, alkaloids and phenolics. The results of the anti-inflammatory activity test of methanol extract have moderate anti-inflammatory potential with an IC50 value of 196,29 ppm. Keywords: Chrysopyllum cainito L, Secondary metabolites, Anti-inflammatory, 50% inhibition concentration.
SKRINING FITOKIMIA DAN BIOAKTIVITAS RHODOMYRTUS TOMENTOSA (AITON) HASSK) (KARAMUNTING) Erwin, Erwin; Ilham, Muhammad Hafid; Pratiwi, Djihan Ryn; Alimuddin, Alimuddin
PROSIDING SEMINAR KIMIA Vol 2 No 2 (2024): Prosiding SNKT III 2023
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Rhodomyrtus tomentosa (Aiton) Hassk) or known as Karamunting, is one of the medicinal plants. This medicinal plant is used by the community as a medicine for colic, fever, dysentery, sepsis, to treat shortness of breath or pain, tuberculosis, abscesses, bleeding and gynecopathy. In this study, phytochemical and bioactivity tests will be carried out on Rhodomyrtus tomentosa leaves, stem and bark extracts. Research methods include maceration of the sample with methanol, separation of the filtrate solvent obtained from the extract using a rotary evaporator, determination of chemical content using a phytochemical test, and determination of bioactivity using the brine shrimp lethality test (BSLT) method. Based on the results of phytochemical tests, it was found that the leaf extract contained alkaloids, steroids, phenolics, flavonoids, saponins and quinones. Stem extract contains alkaloids, phenolics, flavonoids, saponins and quinones. and stem bark extract contains triterpenoids, phenolics, saponins and quinones. Meanwhile, the results of the bioactivity test showed that only the leaf extract was toxic to Artemia salina shrimp with an LC50 of 582.10 ppm, while the leaf and stem bark extracts were inactive with an LC50 value above 1000 ppm. Keywords: Karamunting, BSLT test, phytochemical test, and Artemia Salina L
PENGARUH ION LOGAM TERHADAP AKTIVITAS LIPASE DARI BAKTERI AIR BEKAS GALIAN TAMBANG DI SAMARINDA Haeruddin, Haeruddin; Astuti, Winni; Pratiwi, Djihan Ryn
PROSIDING SEMINAR KIMIA Vol 2 No 1 (2023): Prosiding SNK 2023
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Addition of metal ions on lipase activity has been done. The aim of this research is to find out the effect of metal ions on lipase activity from water bacterial post mining in Samarinda. Lipase activity was determined based on the Titrimetric method with olive oil as a substrate. The result showed lipase activity from water bacterial post mining without the addition of metal ions is 1,0 U/mL and with the addition of metal ions Mg2+, K+, Fe3+, Ca2+, dan Ba2+their respective lipase activities is 0,6 U/mL, 0,7 U/mL, 1,9 U/mL, 1,4 U/mL dan 0,8 U/mL. The conclusion that can be drawn that is metal ions K+, Mg2+ and Ba2+ inhibit lipase activity with a relative activity each at 70; 60 dan 80% while Ca2+ increase lipase activity with a relative activity at 140% and Fe3+ causes denatured lipase with a relative activity at 190%. Keywords: Bacteria, Lipase, Metal Affect
PENENTUAN VARIASI KOMPOSISI DAN pH OPTIMUM ADSORBEN KITOSAN-Fe3O4 BERDASARKAN PERSEN PENYERAPAN ION Pb2+ Lianasari, Ika Yekti; Koesnarpadi, Soerja; Pratiwi, Djihan Ryn; Munandar, Aris
JURNAL ATOMIK Vol 8 No 1 (2023)
Publisher : Jurusan Kimia FMIPA UNMUL

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Abstract

Previously, the synthesis of Chitosan-Fe3O4 adsorbent from magnetite (Fe3O4) made from ferrous ammonium sulfate (III) and ferrous ammonium sulfate (II) in a ratio of 3:1 was carried out. The adsorbent is adjusted with the ratio of magnetite and chitosan composition 1:1; 1:2 and 2:1 with the help of glutaraldehyde as a crosslinker. The results showed that the ratio of the ideal composition is 1:1 with % absorption that is 94.97% in 24 hour, and the optimum pH is obtained at pH 5 with % absorption of 92.18% for Pb2+ ions.
Co-Authors Ade Dinaran Akbar Akbar Akkas, Erwin Allo, Veliyana Londong Ami, Suyatmi Angellina Putri Petrisia Anita Karolina, Anita Arifwan - Aris Munandar Aristina, Reza Fauziah Cahyani, Amelya Putri Chairul Saleh Chairul Saleh Daniel Dewi, Dynda Rosiana Erwin Erwin Erwin Erwin Eva Marliana, Eva Haeruddin Haeruddin Hairani, Rita Hermawan Hermawan Ilham, Muhammad Hafid Indah Ashari Rahmadani Indra Masmur Lianasari, Ika Yekti Magdaleni, Agustina Rahayu Masmur, Hestina Maulina, Sheli Nanang Tri Widodo Nur Hidayah Putri, Amanda Aulia Rabiatul Adawiyah Ritson Purba, Ritson Rudi Kartika, Rudi Ruga, Ritbey Saibun Sitorus Sari, Ika Yekti Liana Soerja Koesnarpadi Subur P Pasaribu Sumarni, Feni Sya'bani, Nurillah Teguh Wirawan, Teguh Tri Riski Amalia Usdin, Muhammad Sadam Vera, Hendrica Mini Wahyu Budi Utama Wahyu Teguh Santoso Winni Astuti Winni Astuti, Winni