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All Journal Universa Medicina Jurnal Biomedika dan Kesehatan Jurnal Jeumpa Jurnal Penelitian dan Karya Ilmiah Lembaga Penelitian Universitas Trisakti Jurnal Pengabdian Masyarakat Trimedika
Rita Khairani, Rita
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Prevalensi diabetes mellitus dan hubungannya dengan kualitas hidup lanjut usia di masyarakat Khairani, Rita
Universa Medicina Vol 26, No 1 (2007)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2007.v26.18-26

Abstract

Latar BelakangDiabetes melitus (DM) merupakan keadaan yang seringkali dikaitkan dengan meningkatnya risiko kesakitan dan kematian. Lanjut usia (lansia) yang menderita DM seringkali juga mengalami penyakit lainnya, ketidakmampuan fisik, gangguan psikososial dan fungsi kognisi, serta meningkatnya pelayanan kedokteran. Pada akhirnya, komplikasi yang terjadi akan mempengaruhi kualitas hidup lansia. MetodePenelitian ini bertujuan untuk memperoleh data tentang besarnya prevalensi DM dan hubungannya dengan kualitas hidup lansia di masyarakat. Penelitian potong lintang dilakukan terhadap 101 lansia melalui wawancara terstruktur, pemeriksaan fisik, antropometri, pemeriksaan gula darah dan penilaian kualitas hidup lansia berdasarkan WHOQOL-BREF. HasilHasil penelitian menunjukkan domain 4 (kondisi lingkungan) mempunyai rata-rata skor tertinggi (14,1 ± 1,8) dan domain 2 (kondisi psikologi) mempunyai rata-rata skor terendah (12,9 ± 1,9). Lansia pria mempunyai rata-rata skor lebih tinggi pada domain kesehatan fisik dan hubungan sosial dibandingkan dengan lansia wanita. Prevalensi DM sebesar 15,8% didapatkan pada kelompok usia 60-70 tahun dan lansia wanita memiliki prevalensi lebih tinggi dari lansia pria. Rata-rata skor domain kondisi lingkungan lebih tinggi bermakna pada lansia yang tidak menderita DM dan rata-rata skor kesehatan fisik lebih tinggi bermakna pada lansia yang menderita obesitas. Semakin besar indeks massa tubuh maka skor domain kesehatan fisik akan semakin meningkat secara bermakna. Semakin tinggi kadar gula darah puasa maka skor domain kesehatan lingkungan akan semakin menurun secara bermakna. KesimpulanKadar gula darah yang tinggi menurunkan kualitas hidup lansia. Intervensi pada lansia yang mengalami DM harus direncanakan untuk memperbaiki kualitas hidup lansia.
Strategi mix-and-match vaksin COVID-19, seberapa efektifkah? Khairani, Rita
Jurnal Biomedika dan Kesehatan Vol 4 No 3 (2021): Ahead of Print
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2021.v4.87-89

Abstract

Dibandingkan dengan perkembangan vaksin COVID-19, kemunculan banyak varian baru menyebabkan peningkatan mortalitas dan morbiditas, distribusi vaksin secara global, ketersediaan suplai vaksin yang terbatas dan kejadian ikutan pasca imunisasi. Hal ini memunculkan kekhawatiran penurunan efektivitas vaksin yang telah ada. Setelah laporan kejadian tromboemboli akibat penggunaan ChAdOx1-nCoV-19 dari AstraZeneca, beberapa negara Eropa mulai meneliti tentang penggunaan vaksin yang berbeda dengan dosis pertama atau yang disebut strategi mix-and-match atau vaksin heterolog.(1) Vaksin heterolog melibatkan pemberian antigen penyakit yang sama atau serupa melalui dua tipe vaksin berbeda, dosis pertama untuk membentuk sistem imun dan dosis berikutnya dengan tipe berbeda untuk meningkatkan respon imun.(2) Beberapa jenis vaksin yang banyak diteliti dalam konsep vaksin heterolog ini diantaranya kombinasi vaksin chimpanzee adenovirus-vectored vaccine (ChAdOx 1 nCoV-19) atau AstraZeneca dengan vaksin mRNA-1273 atau vaksin Moderna, dan vaksin BNT162b2 atau vaksin Pfizer.(3,4)
Obesity is the most influential risk factor of cardiopulmonary endurance in older women Khairani, Rita; Adriani, Donna; Amani, Patwa
Universa Medicina Vol. 40 No. 3 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.254-262

Abstract

BackgroundPulmonary function decreases with age. Similarly, physical exercise capacity measured by maximal oxygen uptake, which is one indicator to measure the level of cardiac and pulmonary vascular resistance, decreases by >1% per year. This results in many respiratory diseases that occur in older persons, especially in obese older persons. Pulmonary function is a basic component of cardiopulmonary endurance, besides other factors such as age, hemodynamics, metabolism, and lifestyle. The objective of this study was to determine whether body mass index (BMI) and pulmonary function have a significant association with cardiopulmonary endurance in older women. MethodsThe study used a cross-sectional design involving 66 subjects aged 60 years and older in South Jakarta. Data was collected by measuring body mass index (BMI), pulmonary function (FEV1, FVC, FEV1/FVC) and maximal oxygen uptake (VO2 max) for cardiopulmonary endurance. Data analysis used simple and multiple linear regression tests in SPSS v.25, with p<0.05. ResultsOf the 66 older persons, 57.6% was obese. Pulmonary function of subjects showed restriction (33.3%), obstruction (6.1%) and a combination of restriction and obstruction (1.5%). Furthermore, mean VO2 max was 12.2 mL/kg/min. Multiple linear regression analysis showed a significant association of BMI and FEV1/FVC with VO2 max (â =-0.56; 95% CI=-0.81 - (-) 0.31; p=0.000; â =0.09; 95% CI=0.01-0.18; p=0.028). BMI was the most influential risk factor of VO2 max (Beta = -0.46). ConclusionsThere was a significant association of BMI and FEV1/FVC with VO2 max, BMI being the most influential risk factor of cardiopulmonary endurance in older women.
TEKNIK BUDIDAYA BLACK SOLDIER FLY (Hermetia illucens) khairani, rita; Jayanti, Sri; Herika, Herika; A, Muhammad; Rafiqah, Rafiqah
Jurnal Jeumpa Vol 4 No 1 (2017): Jurnal Jeumpa
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Penelitian ini bertujuan untuk mengetahui teknik budidaya lalat black soldier fly (Hermetia illucens). Penelitian dilaksanakan di Dusun Bukit, Desa Paya Bujok Seuleumak, Kecamatan Langsa Baro, Kota Langsa pada bulan April sampai Mei 2017. Penelitian ini menggunakan satu teknik perangkap serangga yaitu sweep net. Hasil penelitian menunjukkan media fermentasi bekatul dengan kombinasi sampah organik dapat dijadikan pakan yang cocok dalam budidaya lalat black soldier fly (Hermetia illucens). Proses budidaya dapat dilakukan dengan pemancingan lalat black soldier fly (Hermetia illucens) menggunakan fermentasi bekatul dan sampah organik di alam. Fermentasi bekatul akan mengeluarkan bau khas yang memancing lalat black soldier fly untuk mendatangi tempat pemancingan. Selanjutnya proses budidaya dapat dilakukan di tempat tertutup menggunakan kandang berukuran 2m x 1m x 2,5m.
KORELASI SESAK NAPAS DENGAN OBSTRUKSI SALURAN NAPAS PADA PASIEN PENYAKIT PARU OBSTRUKTIF KRONIK Khairani, Rita; Qalbiyah, Sakinah
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 7, Nomor 1, Januari 2022
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v7i1.12928

Abstract

Latar Belakang: Penyakit paru obstruktif kronik (PPOK) merupakan penyakit inflamasi kronik saluran napas yang dapat menyebabkan obstruksi saluran napas dan ditandai dengan penurunan aliran udara yang persisten. Prevalensi di Indonesia mencapai 3,7% di tahun 2018. Pasien PPOK memiliki beberapa gejala, yaitu mengi, batuk, sesak napas serta produksi sputum yang bertambah yang disebabkan oleh obstruksi saluran napas.Penyakit ini dapat dicegah dan diobati, tetapi apabila disertai dengan seringnya eksaserbasi dan disertai komorbid maka kondisi pasien dapat memburuk.Metode yang digunakan adalah studi analitik dengan desain potong lintang. Pengambilan sampel dilakukan pada bulan November – Desember 2019 di RSUD Budhi Asih dengan cara consecutive non random sampling. Variabel yang diteliti adalah obstruksi saluran napas yang diukur menggunakan Peak Flow Meter dan sesak napas menggunakan kuesioner Modified Medical Research Council . Analisis univariat berupa distribusi frekuensi variabel yang diteliti.  Analisis bivariat untuk menilai koefisien korelasi dengan uji normalitas Kolmogorov-Smirnov, uji korelasi Pearson variabel usia dan sesak napas dengan obstruksi saluran napas, uji T-Independent jenis kelamin dengan obstruksi saluran napas dengan tingkat kemaknaan p<0.05Pada studi ini didapatkan korelasi negatif yang kuat (r=-0.838) dan bermakna (p=0.000) antara skala sesak napas dengan arus puncak ekspirasi  pada pasien PPOK.Kesimpulan : semakin tinggi skala sesak napas maka semakin rendah nilai arus puncak ekspirasi yang didapat
HUBUNGAN KADAR TROMBOSIT DAN KADAR LIMFOSIT TERHADAP DERAJAT GEJALA PADA PASIEN COVID-19 Ekklesia, Josephine Maria; Khairani, Rita
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 9, Nomor 1, Januari 2024
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v9i1.17968

Abstract

Corona virus disease 2019 (COVID-19) merupakan infeksi sistemik yang mengganggu sistem imun dan kondisi hemostasis tubuh. Manifestasi klinis yang ditimbulkan bervariasi. Pemeriksaan hematologi menjadi pemeriksaan diagnostik yang cukup baik dalam menilai perkembangan penyakit. Selain tersedia luas, pemeriksaan ini terjangkau, efisien waktu dengan hasil yang akurat. Beberapa penelitian menemukan kadar trombosit dan limfosit yang abnormal berperan sebagai salah satu faktor yang mempengaruhi tingkat mortalitas pada derajat infeksi SARS-CoV-2. Untuk dapat membuktikan peran parameter trombosit dan limfosit, maka perlu dilakukan penelitian untuk menilai adanya hubungan antara derajat gejala yang dialami pasien COVID-19. Metode yang digunakan pada penelitian ini adalah studi observasional dengan desain potong lintang. Responden yang terlibat merupakan pasien COVID-19 di RSUD Budhi Asih Jakarta yang memenuhi kriteria inklusi dan eksklusi yang telah ditetapkan. Pengambilan data menggunakan data sekunder rekam medis yang digunakan untuk menentukan derajat gejala pasien, dan hasil pemeriksaan laboratorium darah terkait. Analisis data dilakukan dengan SPSS for Windows menggunakan uji Fisher Exact dan uji Chi-square dengan tingkat kemaknaan sebesar 0,05. Pada hasil penelitian ini didapatkan hubungan bermakna antara kadar trombosit (p = 0,023) dan kadar limfosit (p < 0,001) dengan derajat gejala COVID-19. Penelitian ini menyimpulkan, terdapat hubungan yang bermakna antara kadar trombosit dan kadar limfosit terhadap derajat gejala pada pasien COVID-19.
EDUKASI GASTROENTERITIS AKUT DAN SINDROM DISPEPSIA DENGAN PENDEKATAN KEDOKTERAN KELUARGA Tjahjadi, Joey Joshua V Tjahjadi; Zahrotusyifa, Aila; Ersya , M Naufal; Arya , M. Fauzan; Davega, Mutia; Ghaniyya , Nabiila; Khairani, Rita
Jurnal Pengabdian Masyarakat Trimedika Vol. 1 No. 1 (2024)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v1i1.19015

Abstract

Acute gastroenteritis is an inflammation of the stomach and intestines that causes symptoms such as diarrhea, nausea and vomiting lasting less than 14 days. Dyspepsia syndrome is a collection of symptoms commonly found in the community, characterized by a sensation of pain or discomfort in the upper area of the solar plexus. The aim of this activity is to determine the description and causes of acute gastroenteritis and dyspepsia syndrome using the principles of a family medicine approach based on evidence based medicine in patients by identifying risk factors, clinical problems, and patient management using a patient centered approach and family approach. Methods are obtained through history taking and physical examination. Home visits were done to obtain a complete data and to do an analysis on the family’s medicine, psycho-social and environmental surroundings. Those Analysis includes holistic family medicine diagnosis and family function management plan. The results showed that a 59-year-old woman suffering from acute gastroenteritis and dyspeptic syndrome who has internal risk factors such as age approaching old age category, irregular eating patterns with unhygienic eating habits, education has been carried out for patients and their families about disease, drugs, lifestyle, and proper diet. The conclusion is a process of changing the patient's behavior to control food hygiene and maintain regular meal times, always wash hands especially before eating to prevent recurrence of the disease. The role and attention of the family is very important in the care and management of sick family members.
PENYULUHAN BAHAYA POLUSI UDARA PADA MASYARAKAT DI KELURAHAN RAWA BUAYA JAKARTA BARAT Khairani, Rita; Hastuty, Dewi
Jurnal Pengabdian Masyarakat Trimedika Vol. 1 No. 2 (2024)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v1i2.20667

Abstract

DKI Jakarta as the capital city of Indonesia is a center of various activities and higher population density than other provinces. The transportation sector is the largest contributor to air pollution from motor vehicles. In the World Air Quality Report 2023, Jakarta ranks seventh for the world's most polluted cities. Long-term exposure to air pollution will be the beginning of various diseases, such as respiratory disease, heart disease, stroke, congenital diseases, and malignancy. Air pollution is the invisible cause of death of 29% of lung cancer deaths, and 25% of heart disease deaths. The need for a good understanding of the impact of air pollution on respiratory health is the background of health service activity. This activity was held on Saturday, November 4th, 2023 at GKI Pakis Raya, Rawa Buaya subdistrict, West Jakarta, attended by 104 local residents who were dominated by women (87%) with an average age of 47 years. The activity method is carried out by completing a pre-test, counseling with presenting the material, question and answer discussion and ending with a post-test.   The results obtained through this activity were an increase in participants' knowledge about the impact of air pollution on breathing and health as evidenced by an increase in the average post test score of 38.9%. from the previous 53.38 to 79.4. In conclusion, the activity had a positive effect on increasing respondents' knowledge about the impacts of air pollution. The suggestion is by carrying out regular evaluations of behavioral changes after receiving counseling
HUBUNGAN KADAR LEUKOSIT DAN TOTAL LIMFOSIT DENGAN KELAINAN PARU PADA PASIEN COVID-19 Putra, Andika Fauzan; Khairani, Rita
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 9, Nomor 2, Juli 2024
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v9i2.18466

Abstract

The impact of COVID-19 infection on the lungs is very broad. This lung organ disorder will affect the prognosis and also the patient’s quality of life. Markers are needed to identify the patient’s condition or patient’s prognosis so that they can estimate the patient’s condition from the start and determine further treatment and abnormalities that can be caused by the infection, especially in the patient’s lung organs. This study aims to reduce the incidence of post-COVID-19 pulmonary fibrosis by assessing the relationship between leukocyte levels and total lymphocyte count with lung abnormalities in COVID-19 patients. This research is an analytical study with a cross-sectional design using secondary data in the form of medical records from COVID-19 patients at the Budhi Asih Teaching Hospital, East Jakarta, with a total of 112 subjects. The data taken were leukocyte levels and total lymphocyte count based on laboratory results, and information on the patient’s pulmonary abnormalities documented in the medical record. The data were then analyzed by Chi-square test. The significance value used is p<0.05. Pneumonic lung abnormalities were dominated by increased leukocyte levels in 62 people (91.2%) and decreased total lymphocyte count in 63 people (94.1%). Leukocyte levels have a significant correlation with lung disorders (p = 0.021). The same thing was also shown by the total lymphocyte count which had a significant relationship with lung disorders (p = 0.001). There is a significant correlation between leukocyte levels and total lymphocyte count with lung abnormalities in COVID-19 patients.
Human Metapneumovirus (hMPV): Tantangan Baru dalam Kesehatan Global Khairani, Rita
Jurnal Biomedika dan Kesehatan Vol 8 No 1 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2025.v8.1-5

Abstract

Human metapneumovirus (hMPV) is a respiratory virus belonging to the Pneumoviridae family, first identified in 2001. hMPV is closely related to respiratory syncytial virus (RSV), causing upper and lower respiratory tract infections that primarily affect vulnerable populations, such as children, the elderly, and individuals with weakened immune systems. It often circulates seasonally during winter and early spring. The incidence of hMPV is highest in young children. It is responsible for 5-10% of acute respiratory infections in hospitalized children and causes a crude mortality rate of 9%, similar to influenza A. Symptoms of hMPV infection vary from mild upper respiratory tract infections to bronchiolitis, bronchitis, and pneumonia. Nasal congestion and runny nose, cough, sore throat, and fever are common symptoms of this infection. Wheezing is common in children and requires the use of bronchodilators. Most hMPV patients recover within 7-10 days without complications. Some groups are at high risk for severe complications such as pneumonia and multi-organ failure requiring intensive care. Currently, laboratory diagnosis of hMPV infection is done by detecting viral nucleic acid in respiratory tract specimens. Serological tests using Immunofluorescence or ELISA (Enzyme-Linked Immunosorbent Assay) can be used to detect hMPV-specific antibodies, which are helpful in retrospective diagnosis and epidemiological studies. Rapid antigen tests, although practical, can vary in sensitivity and specificity. There is currently no specific treatment, and vaccination is still in the development stage, although significant progress has been made. Prevention remains the most important aspect in reducing the impact of hMPV, focusing on infection control to limit the spread of the virus, especially in vulnerable populations.
Co-Authors A, Muhammad Adriani, Donna Arya , M. Fauzan Davega, Mutia Ekklesia, Josephine Maria Ersya , M Naufal Ghaniyya , Nabiila Hairunisa, Nany Herika, Herika Iskandar, Dian Jayanti, Sri Kencana, Gita Khairunisa, Adinda Lestari, Ade Dwi Nugraha, Alfjari Febri Patwa Amani, Patwa Putra, Andika Fauzan Putri, Mustika Anggiane Qalbiyah, Sakinah Rafiqah, Rafiqah Ridwan, Alvin Mohamad Sembiring, Rinawati Setyaningrum, Dyah Ayu Woro Tjahjadi, Joey Joshua V Tjahjadi Zahrotusyifa, Aila