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All Journal Universa Medicina Jurnal Biomedika dan Kesehatan Jurnal Penelitian dan Karya Ilmiah Lembaga Penelitian Universitas Trisakti JUARA: JURNAL WAHANA ABDIMAS SEJAHTERA The Journal of Society Medicine (JSOCMED) AMMA : Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Trimedika Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Adriani, Donna
Faculty of Medicine, Trisakti University
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Combination of aerobic exercise and Hibiscus sabdariffa Linn. increased nitric oxide in rats Adriani, Donna; Siagian, Minarma; Irawati, Dewi
Universa Medicina Vol 36, No 2 (2017)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2017.v36.80-87

Abstract

Background Hypertension and myocardial infarction account for the high rate of mortality globally. Hibiscus sabdariffa (HS) Linn. is rich in antioxidants and previous studies have demonstrated its anti-hypertensive effects. Several studies show that regular physical activity is an important component to reduce cardiovascular mortality. The objective of this study was to evaluate the effects of a combination of aerobic exercise and HS extract on nitric oxide (NO) and endothelin-1 (ET-1) in rats. MethodsAn experimental study was conducted on 36 male Wistar rats, aged 4 weeks and 60-70 g in weight. The interventions were aerobic exercises and HS at 400 mg/kg BW/day administered for 4, 8 and 12 weeks. The rats were randomized into 12 groups: 3 control groups (C4, C8, C12), 3 aerobic exercise groups (A4, A8, A12), 3 HS groups (H4, H8, H12), and 3 combination groups [aerobic exercise and HS] (HA4, HA8, HA12). After 4, 8, and 12 weeks, the rats were sacrificed and their abdominal aorta was collected for determination of nitric oxide and ET-1 concentrations. One way ANOVA was used to analyze the data. ResultsThere was a significant difference in NO levels between all groups, with the 4-week aerobic exercise group (A4) showing the highest NO levels compared to the other eleven groups (p<0.05). In contrast, the ET-1 levels were not significantly different between all groups. Conclusions This study demonstrated that the combination of HS supplementation and aerobic exercise increases NO in rats, and provided further evidence to the traditional use of the plant as an antioxidants agent.
Effect of Brain Gym ® exercises on cognitive function and brain-derived neurotrophic factor plasma level in elderly: a randomized controlled trial Adriani, Donna; Imran, Yudhisman; Mawi, Martiem; Amani, Patwa; Ilyas, Ermita I.I.
Universa Medicina Vol 39, No 1 (2020)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (545.732 KB) | DOI: 10.18051/UnivMed.2020.v39.34-41

Abstract

BackgroundCognitive impairment and dementia are some of the major health concerns in the aging population. Many studies showed positive effects of physical exercise in delaying or preventing these conditions. Brain Gym ® exercises is a structured aerobic exercise involving head, eyes and crossing movements of the extremities in order to stimulate both brain hemispheres. This study was conducted to evaluate the effect of Brain Gym ® exercises sessions on cognitive function and plasma brain-derived neurotrophic factor (BDNF) in the elderly.MethodsA non-blinded randomized controlled study involving 64 healthy women aged >60 years who were randomized into Brain Gym ® exercises treatment group (n=32) and control group (n=32). Treatment group joined 60 minutes of brain gym exercises sessions twice a week for 12 weeks. The measured outcomes were cognitive function (assessed by mini-mental state examination [MMSE] questionnaire) and plasma BDNF levels. The outcomes were measured at base-line and after the intervention. An independent t-test was used to analyze the data.ResultsThe BDNF levels were increased in both groups after 12 weeks, and there was a significant difference between treatment group (41.26 ± 6,82 ng/mL) and control group (37.10 ± 8.11 ng/mL)(p=0.040). However, the MMSE score was not significantly different between the two groups (p=0.200).ConclusionBrain Gym ® exercises sessions significantly increase plasma BDNF level in the elderly population. In practical terms, we may suggest evaluation of the effects of Brain Gym ® exercises as a strategy in the treatment of disorders associated with central degenerative changes.
Low 25-hydroxyvitamin D level increases carotid intima-media thickness in elderly women Imran, Yudhisman; Aswar, Andini; Rachmiyani, Irmiya; Adriani, Donna
Universa Medicina Vol 38, No 2 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2019.v38.114-120

Abstract

BackgroundCerebrovascular disease occurs due to atherosclerosis of the carotid artery triggered by endothelial dysfunction, which can be assessed by measuring the carotid intima-media thickness (CIMT). There are several risk factors contributing to endothelial dysfunction, such as 25-hydroxyvitamin D [25(OH)D] deficiency. A number of research studies have shown variable results on the relationship between 25(OH)D deficiency and endothelial dysfunction. The objective of the present study was to determine the relationship between 25(OH)D and CIMT in elderly women.METHODS A cross-sectional study was conducted involving 45 elderly women aged ≥60 years. The inclusion criteria were: able to communicate well and able to walk actively without any help. The exclusion criteria were: not having diabetes mellitus, stroke, heart disease, kidney disease, not consuming vitamin D or medicines containing corticosteroids, and not using hormone replacement therapy. Laboratory examination was conducted for fasting blood sugar, lipid profile, and 25(OH)D. CIMT was measured using carotid Doppler ultrasonography at the left carotid artery. Simple linear regression analysis was used to analyze the data.RESULTSMean 25(OH)D level was 11.753 ± 4.027 ng/mL, and mean CIMT 0.61 ± 0.10 mm. Simple regression analysis showed a significant relationship between 25(OH)D level and CIMT (β=-0.001; 95% C.I.=-0.020-0.003; p=0.009).CONCLUSION Our data suggest an inverse association between 25(OH)D level and CIMT in elderly women. This study supports the protective role of vitamin D against subclinical atherosclerosis in elderly women.
Obesity is the most influential risk factor of cardiopulmonary endurance in older women Khairani, Rita; Adriani, Donna; Amani, Patwa
Universa Medicina Vol. 40 No. 3 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.254-262

Abstract

BackgroundPulmonary function decreases with age. Similarly, physical exercise capacity measured by maximal oxygen uptake, which is one indicator to measure the level of cardiac and pulmonary vascular resistance, decreases by >1% per year. This results in many respiratory diseases that occur in older persons, especially in obese older persons. Pulmonary function is a basic component of cardiopulmonary endurance, besides other factors such as age, hemodynamics, metabolism, and lifestyle. The objective of this study was to determine whether body mass index (BMI) and pulmonary function have a significant association with cardiopulmonary endurance in older women. MethodsThe study used a cross-sectional design involving 66 subjects aged 60 years and older in South Jakarta. Data was collected by measuring body mass index (BMI), pulmonary function (FEV1, FVC, FEV1/FVC) and maximal oxygen uptake (VO2 max) for cardiopulmonary endurance. Data analysis used simple and multiple linear regression tests in SPSS v.25, with p<0.05. ResultsOf the 66 older persons, 57.6% was obese. Pulmonary function of subjects showed restriction (33.3%), obstruction (6.1%) and a combination of restriction and obstruction (1.5%). Furthermore, mean VO2 max was 12.2 mL/kg/min. Multiple linear regression analysis showed a significant association of BMI and FEV1/FVC with VO2 max (â =-0.56; 95% CI=-0.81 - (-) 0.31; p=0.000; â =0.09; 95% CI=0.01-0.18; p=0.028). BMI was the most influential risk factor of VO2 max (Beta = -0.46). ConclusionsThere was a significant association of BMI and FEV1/FVC with VO2 max, BMI being the most influential risk factor of cardiopulmonary endurance in older women.
Effective skin care management in postmenopausal women Saroso, Ade Firman; Sutanto, Hans Utama; Adriani, Donna; Rachmiyani, Irmiya; Khusfiani, Triasti; Putri, Mustika Anggiane
Journal of Society Medicine Vol. 2 No. 10 (2023): October
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i10.98

Abstract

Menopause-induced hormonal changes can lead to skin problems. The decline in estradiol levels can adversely affect various physiological functions, including skin changes like atrophy, wrinkles, poor wound healing, and a decline in perceived facial attractiveness due to reduced hydration. Effective skincare that can be done to prevent the above problems is by drinking 8 glasses of water a day, consuming vitamins, one of which is vitamin C, consuming antioxidants, using sunscreen, using facial moisturizer, and cleaning your face properly and appropriately. Vitamin C has antioxidant properties and plays an important role in collagen formation. Vitamin C is often found as a constituent of the dermis and epidermis layers in normal skin. However, due to the aging process, the vitamin C content in the dermis and epidermis layers could decrease. Vitamin C has been shown to stabilize collagen mRNA, thereby increasing collagen synthesis to improve skin aging. By implementing these strategies, postmenopausal women can effectively manage skincare and maintain healthy, beauty, vibrant, and glowing skin that looks and feels great.
HUBUNGAN INDEKS MASSA TUBUH DENGAN KADAR HBA1C PADA PENDERITA DIABETES MELITUS TIPE-2 Hurin, Salsabila; Adriani, Donna
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 8, Nomor 2, Juli 2023
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v8i2.14034

Abstract

BACKGROUND Diabetes mellitus (DM) is a state of increased sugar levels in the blood vessels. DM can interfere with organ function and cause death. One of the criteria for diagnosing DM based on ADA is HbA1c. In 2019, 463 million people with DM aged 20 to 79 years worldwide. DM sufferers are estimated to increase every year due to risk factors: race, age, gender, lack of physical activity, unhealthy and unbalanced diet, overweight or obesity. Overweight or obesity is detected by calculating the Body Mass Index. The purpose of this study was to determine the relationship between body mass index and HbA1c levels in patients with type-2 diabetes mellitus. METHODS Observational analytic study with cross-sectional design. The total sample is 90 respondents obtained from medical record data at RSUD dr. Soekardjo Tasikmalaya City in type-2 DM patients. Data analysis was performed using Fisher's exact test on the SPSS version 25 program. RESULTS Characteristics of respondents who are >45 years old (82.2%) and female (71.1%). There was no significant relationship between age and HbA1c (p-value = 0.633). There was no significant relationship between BMI and HbA1c (p-value = 0.011). CONCLUSIONS In this study, there was no significant relationship between body mass index and HbA1c levels in patients with type-2 diabetes mellitus. BMI should be considered when using the HbA1c assay to diagnose and manage type-2 diabetes.
HUBUNGAN LINGKAR PINGGANG DENGAN KEJADIAN OSTEOPOROSIS PADA WANITA LANSIA Adriani, Donna; Wahid, Salma Dhiya
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 7, Nomor 2, Juli 2022
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v7i2.14035

Abstract

BACKGROUND In elderly women, there is estrogen reduction which causes parathyroid depression and results in decreased absorption of vitamin D and experiences the aging process. This leads to increased susceptibility to one of the metabolic diseases, osteoporosis. One of the risk factors for osteoporosis is nutritional status which can be assessed through bmi and waist circumference. This study determines the relationship between waist circumference and the incidence of osteoporosis in elderly women. METHOD The study used an observational study with a cross-sectional design that included 86 elderly women in November-December 2021 at the Puskesmas Mampang, South Jakarta. Sampling used nonrandom sampling method with consecutive sampling technique. Data were collected by interview using the FRAX® tool questionnaire for osteoporosis and measuring waist circumference with a measuring tape. Data were analyzed by chi-square statistical test with a significance value of p<0.05. RESULTS The most age group experiencing osteoporosis is at the age of 71-90 years as many as 15 respondents 78.9%. There was a significant relationship between age and osteoporosis in elderly women (p-value = 0.028). Respondents who had osteoporosis with a waist circumference of <80 cm had (64.7%) more than those with a waist circumference of >80 cm. There was no significant relationship between waist circumference and osteoporosis in elderly women (p = 0.242). CONCLUSION There is a significant relationship between age and osteoporosis in elderly women and there is no relationship between waist circumference and osteoporosis in elderly women  
PERAN KADAR HEMOGLOBIN PADA KEBUGARAN JASMANI REMAJA Fadilah, Tersanova; Adriani, Donna
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 8, Nomor 2, Juli 2023
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v8i2.14312

Abstract

Physical fitness becomes a problem in Indonesia because it is categorized in the poor category, especially for adolescents aged 10-19 years. Adolescents are expected to have good physical fitness as they are about to enter productive age. Physical fitness is defined as the ability of a person to perform daily physical tasks optimally, even doing several additional physical activities without causing significant fatigue. Factors that affect a person's physical fitness consist of internal and external factors. Internal factors refer those that have settled from within the body such as genetics, age, and gender. Meanwhile, external factors include physical activity, nutritional status, health status, adequate rest, smoking habit, and haemoglobin levels. Haemoglobin is a protein complex consisting of haeme and globin, rich in iron, and whose function is to carry oxygen from the lungs to body tissues or throughout the body. Anaemia define when the haemoglobin levels in a person's blood is lower than normal. Anaemia is a problem in various communities all over the world, especially in developing countries such as Indonesia. According to the Ministry of Health of Indonesia in 2013, the prevalence rate of anaemia in all age groups was 21.70%. Symptoms of low haemoglobin levels are weakness, fatigue, poor work productivity, and difficulty in concentrating. This mechanism is caused by decreased oxygen uptake and reduced oxygen capacity to be transported to body tissues, affecting physical fitness. This literature review discusses the role of haemoglobin levels in physical fitness, in order to improve physical fitness.
HUBUNGAN SKOR PAPARAN MATAHARI DENGAN HASIL SKRINING RHINITIS ALERGI Putri, Mustika Anggiane; Rosita, Silvi Zahra; Adriani, Donna
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 8, Nomor 1, Januari 2023
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v8i1.14935

Abstract

ABSTRAK LATAR BELAKANG : Rhinitis alergi adalah kumpulan gejala akibat proses inflamasi pada mukosa hidung yang diperantarai oleh immunoglobulin E. Rhinitis alergi banyak ditemukan di usia sekolah dan juga dewasa muda. Peningkatan penyakit alergi di seluruh dunia dikaitkan dengan kadar vitamin D yang rendah dalam darah. Kadar vitamin D yang rendah dikaitkan dengan paparan matahari yang rendah. TUJUAN : penelitian untuk mengetahui hubungan skor paparan matahari dengan rhinitis alergi pada anak usia 13-15 tahun. METODE : Studi analitik observasional dengan desain cross sectional. Metode pengambilan sampel yang digunakan adalah cluster random sampling dengan sampel sebanyak 114 responden. Analisis data dilakukan secara univariat dan bivariat dengan uji statistik fisher’s exact menggunakan program SPSS versi 25 dengan nilai p<0,05 berbeda bermakna. HASIL : Hasil analisis data menunjukkan bahwa didapatkan skor paparan matahari adalah mayoritas rendah sedangkan hasil skrining rhinitis alergi adalah mayoritas tidak dikategorikan rhinitis alergi. Hasil analisis menunjukkan bahwa tidak terdapat hubungan antara skor paparan matahari dengan hasil skrining rhinitis alergi pada anak usia 13-15 tahun (p value = 1,000). KESIMPULAN : Prevalensi rhinitis alergi pada anak usia 13-15 tahun adalah 7,9%. Tidak terdapat hubungan antara skor paparan matahari dengan hasil skrining rhinitis alergi pada anak usia 13-15 tahun. ABSTRACT BACKGROUND: Allergic rhinitis is a collection of symptoms due to an inflammatory process in the nasal mucosa mediated by immunoglobulin E. Allergic rhinitis is commonly found in school age and young adults. The worldwide increase in allergic disease is associated with low blood levels of vitamin D. Low vitamin D levels are associated with low sun exposure. THE AIM: this study was to determine the relationship between sun exposure scores and allergic rhinitis in children aged 13-15 years. METHOD: Observational analytic study with cross sectional design. The sampling method used is cluster random sampling with a sample of 114 respondents. Data analysis was carried out univariate and bivariate with fisher's exact statistical test using SPSS version 25 program with p value <0.05 significantly different. RESULT: The results of data analysis showed that the majority of sun exposure scores were low while the screening results of allergic rhinitis majority were not categorized as allergic rhinitis. The results of the analysis showed that there was no relationship between sun exposure scores and the results of allergic rhinitis screening in children aged 13-15 years (p value = 1,000). CONCLUSION: The prevalence of allergic rhinitis in children aged 13-15 years is 7.9%. There is no relationship between sun exposure scores and the results of allergic rhinitis screening in children aged 13-15 years.
MENGHAFAL AL-QURAN: TINJAUAN FUNGSI KOGNITIF Adriani, Donna; Amani, Patwa; Putri, Mustika Anggiane; Imran, Yudhisman; Fauzi, Ahmad
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 9, Nomor 1, Januari 2024
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v9i1.17487

Abstract

Cognitive function is a mental process consisting of knowledge, information processing, and reasoning. Cognitive functions include the domains of perception, memory, learning, attention, decision-making, and language skills. Assessment of cognitive functions consists of attention and concentration, executive function, memory, language, visuoconstruction skills, conceptual thinking, calculation, and orientation. Cognitive disorder is a maladaptive response characterized by impaired memory, disorientation, incoherence and difficulty thinking logically. Memorization involves various complex processes called basic cognitive processes which include encoding, storing, and recalling memories, because these processes occur in many memory systems that function differently but are interconnected with one another. Al-Quran is the holy book of Muslims that comes from Allah SWT and was revealed through the Prophet Muhammad SAW. Memorizing the Al-Quran can stimulate the neurotrophin factor. In adulthood, there is a decrease in cognitive function of 6.7%. Cognitive function can be assessed from the serum levels of Brain Derived Neurotrophic Factor (BDNF) and serum Nerve Growth Factor (NGF). Brain Derived Neurotrophic Factor is a protein that increases the survival of neurons and synapses that play a role in learning and memory processes. Nerve Growth Factor is a protein that plays a role in the growth, development and maintenance of nerve cells. The purpose of this study is to explain physiologically the effect of memorizing the Al-Quran on cognitive function in terms of serum BDNF and NGF levels. Based on the results of several studies, it was found that memorizing the Al-Quran continuously can improve cognitive function.
Co-Authors Ainum, Vanessa Arvasabell, Raissya Keikazita Aswar, Andini Aurora, Malicca Nayya Az Zahra, Fatimah Az-Zahra, Athaya Ulima Azahra, Aurelia Fatima DEWI IRAWATI Diyan, Ikrimah Djamal, Syifa Kamila Ermita I.I. Ilyas Fadhil, Rafly Afif Fadilah, Tersanova Fauzi Ahmad Muda Fayola, Aurelia Putri Handayani, Astri Hurin, Salsabila Jordhi, Dimas Krishna Murthi, Aditya Lestari, Ikrimah Diyan Maharani, Astrid Winesti Maharani, Ni Putu Radela Maizura, Fanny Izzati Martiem Mawi Minarma Siagian Nasution, Dina Putri Nugraha, Alfjari Febri Nurkumala, Kaila Patwa Amani, Patwa Putri Nasution, Dina Putri, Audria Assyfa Salsabila Putri, Mustika Anggiane Rachmiyani, Irmiya Raditya Wratsangka, Raditya Rezlin, Madury Rita Khairani, Rita Rosita, Silvi Zahra Salma, Nabila Maudy Saroso, Ade Firman Sugiri, Nabil Lokeswar Sutanto, Hans Utama Syafitri, Julia Aina Tamarifa, Zhaqina Azizah Triasti Khusfiani Tungka, Endrico Xavierees Wahid, Salma Dhiya Wiludjeng, Arinka Ghita Wongso, Agnes Zenyka Wulandari, Ainurrahmi Yudhisman Imran, Yudhisman Zulkarnain, Salwa Fildzah