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All Journal Jurnal Ilmiah Kedokteran Wijaya Kusuma Paediatrica Indonesiana Jurnal Keperawatan Priority SCRIPTA SCORE Scientific Medical Journal Indonesian Journal of Global Health research Jurnal Kesehatan Mahardika

Fathia Meirina, Fathia

Departemen Ilmu Kesehatan Anak, Fakultas Kedokteran, Universitas Sumatera Utara, Medan

Author-ID : 622278

Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Physics Public Health

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Hematological scoring system as an early diagnostic tool for neonatal sepsis Fathia Meirina; Bidasari Lubis; Tiangsa Sembiring; Nelly Rosdiana; Olga Siregar
Paediatrica Indonesiana Vol 55 No 6 (2015): November 2015
Publisher : Indonesian Pediatric Society

Background Sepsis was the leading cause of death in babies by 30%-50% in developing countries. Early diagnosis of neonatal sepsis is still a difficult problem because of clinical features are not specific. Blood culture is the gold standard, but it takes several days and is expensive. The hematological scoring system (HSS) consists of hematologic parameters (leucocyte count, polymorphonuclear (PMN) cells, degenerative changes, and platelet count) for early diagnosis of neonatal sepsis. Objective To measure HSS as an early diagnostic tool for neonatal sepsis. Methods A cross sectional study was conducted in March to June 2013. Samples were collected by consecutive sampling. Fourty neonates suspected sepsis in neonatology unit H. Adam Malik Hospital, Medan, North Sumatera, underwent routine blood count, blood culture, and peripheral blood smear. Each hematologic parameters were analysed using the HSS of Rodwell et al. The hematologic parameters were total leucocyte count, total PMN cells, total PMN immature, I:T PMN ratio, I:M PMN ratio, degenerative changes, and platelet count. The total value revealed HSS score. Diagnostic study parameters were calculated. Results Ten of fourty neonates had sepsis based on blood culture results. The HSS score >=4 had sensitivity 80%, specificity 90%, with positive predictive value (PPV) 73%, negative predictive value (NPV) 93%, ROC curve showed cut off point 0.902 (95% CI 0.803 to 1.0). Conclusion Score HSS >=4 could be used as an early diagnostic tool for neonatal sepsis.

Tuberculosis risk factors in children with smear-positive tuberculosis adult as household contact Nora Hajarsjah; Ridwan M. Daulay; Oke Rina Ramayani; Wisman Dalimunthe; Rini Savitri Daulay; Fathia Meirina
Paediatrica Indonesiana Vol 58 No 2 (2018): March 2018
Publisher : Indonesian Pediatric Society

Background Children in household contact of adults with smear-positive tuberculosis (TB) are at higher risk of TB infection. Screening of these children is a main strategy for eliminating childhood TB.Objective To determine risk factors of TB among children in household contact with smear-positive adult TB patients.Methods This case-control study was conducted in 5 public health centers at Batu Bara District, North Sumatera. We studied children from birth to 18 year-old living in the same house as adults with smear-positive TB. A tuberculosis scoring system was used to diagnosis TB in the children. Associations between risk factors and the incidence of TB were analyzed using Chi-square, Mann-Whitney U, and logistic regression tests.Results We enrolled 145 children who had household contact with smear-positive adult TB patients. Subjects were allocated to either the case group [TB score >6; 61 subjects (42.0%)] or the control group [TB score <6; 84 subjects (58.0%)]. Bivariate analysis revealed that nutritional status, immunization status, number of people in the house, sleeping in the same bed, and duration of household contact had significant associations with the incidence of TB. By multivariate logistic regression analysis, nutritional status and duration of household contact were significant risk factors for TB, with OR 5.89 and 8.91, respectively.Conclusion Malnutrition and duration of household contact with smear-positive adult TB patients of more than 6 hours per day were risk factors for TB among children.

Co-Authors Amelia, Putri Bidasari Lubis Cindy Rolexza Fadila, Yuriza Fithria Aldy Hamdi, Tasrif Harahap, Juliandi Mayasri, Fadhliani Mayasri, Fadhliani Putri Nelly Rosdiana Nora Hajarsjah Oke Rina Ramayani Olga Siregar Pertin Sianturi Ridho, M Ridwan M. Daulay Rina Amelia Rini Savitri Daulay, Rini Savitri Rita Evalina Rizone, Alifya Shifwah Siska Mayasari Lubis, Siska Mayasari Tiangsa Sembiring Wisman Dalimunthe Wisman Dalimunthe, Wisman

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Journal : Paediatrica Indonesiana