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All Journal Jurnal Anestesiologi Indonesia Jurnal Anestesi Perioperatif Medula Jurnal Kesehatan Andalas Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Indonesian Journal of Anesthesiology and Reanimation (IJAR) Indonesian Journal of Global Health research Narra J Jurnal Neuroanestesi Indonesia Majalah Anestesia & Critical Care (MACC) The Journal of Society Medicine (JSOCMED) Jurnal Pengabdian Pada Masyarakat METHABDI Jurnal Kesehatan Mahardika
Hamdi, Tasrif
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Single-Shot Thoracic Spinal Anesthesia (TSA) In Pediatric Patient Under Laparoscopic Cholecystectomy: A Case Report Ghozali, Imam; Hamdi, Tasrif; Yusmaidi, Yusmaidi; Sitepu, John Frans
Journal of Society Medicine Vol. 1 No. 3 (2022): December
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.059 KB) | DOI: 10.47353/jsocmed.v1i3.15

Abstract

Introduction: Laparoscopy is mostly performed under general anesthesia (GA) but laparoscopy using anesthesia such as thoracic spinal anesthesia (TSA) is mostly performed by some anesthesiologists and it is very useful when compared to GA. Method: This paper presents a case report of the use of TSA in healthy pediatric patients who administered anesthesia with TSA in the T10-T11 interspace, using 1 ml of hyperbaric Bupivacaine 5 mg/ml mixed with: 1 ml of Levobupivacaine isobaric 5 mg/ml, Fentanyl 50 μg, Ketamine 10 mg and Dexmedetomidine 10 μg mixed in 1 syringe. Results: During procedure, hemodynamically stable, no nausea, vomiting, or discomfort. Postoperative recovery process was very smooth, hemodynamically stable, no pain was reported or PDPH (Post Dural Puncture Headache) even though we used a 26G spinal needle. The use of TSA is considered very practical and more economical even though it is still carried out very carefully. Conclusion: This is only one single case report. TSA can be a better choice compare with general anesthesia. Stable hemodynamic during laparoscope and TSA can avoid systemic effect of general anesthesia like cognitive affect after general anesthesia, longer for recovery from anesthesia, nausea, vomiting, poor control pain and high cost.
Transversus Abdominis Plane (TAP) Steroid Block for Chronic Abdominal Pain Caused by Chronic Postoperative Pain Hamdi, Tasrif
Journal of Society Medicine Vol. 2 No. 1 (2023): January
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i1.59

Abstract

Introduction: Various factors including surgical, psychological, amount of acute pain relief have been proposed as risk factors for developing CPSP. Different treatment modalities like nerve and plane blocks, psychiatric counselling have been described to counter this pain. Case: The patient was a 30-year-old female with complaints of severe pain in the right lower quadrant of the abdomen and found a surgical scar with hyperalgesia and a history of open appendicectomy surgery, two times section caesarean section surgery. The patient experienced pain after section caesarean section surgery 6 months ago. Because the pain was also felt in the right hypochondrium, the patient was unable to move his body, unable to sit and stand. The patient was diagnosed as a case of chronic post surgical pain syndrome (CPSP). We performed transversus abdominis plane block (TAP) with ultrasound guidance and lidocaine 15 ml combined with 40mg methylprednisolone. VAS scores showed significant improvement from 8/10 and 2/10 during the 10-day follow-up. We conclude that ultrasound-guided TAP block can be a treatment option for CPSP cases. Conclusion: Chronic post surgical pain (CPSP) is a definite clinical entity after laparatomy. We report a successful management of such a case with ultrasound guided transversus abdominis plane block. The patient had very significant pain relief after procedure follow up continue until today without any side effects.
What is the function of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in pain processes? Hamdi, Tasrif
Journal of Society Medicine Vol. 2 No. 2 (2023): February
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v2i2.63

Abstract

At the cellular level, the pathophysiology of neuropathic pain can be divided into two parts. The first is the early phase (several days) and the second is the late phase (ranging from weeks to months and years). Cancer cell growth in the periphery will cause nerve damage in the periphery and prolonged pain will cause changes in nerve transmission processes in the periphery and centre. This underlies the occurrence of peripheral neuropathic pain. Damage to peripheral nerve tissue will trigger peripheral sensitisation and then central sensitisation. After peripheral nerve cell damage (including axon damage), schwan cells will release MMP-9, initiating macrophage cell infiltration. Then there will be degradation of myelin basic protein. The presence of damaged axons will cause an increase in the number of sodium channels and hyperexcitability of ectopic signals from afferent nerve fibres. The result is a continuous action potential that eventually contributes to central sensitisation characterised by hyperalgesia and allodynia. This review summarizes that neuropathic pain occurs through hyperexcitability (hypersensitisation) of nerve cells is IL-1β, MMP-9 in the early phase, MMP-2 in the late phase and finally microglia and astrocyte cells.
Correlation Analysis of Lemon, IDS, and Wilson Scores in Assessing Intubation Difficulty in Patients Undergoing General Anesthesia Sinaga, Ade; Hamdi, Tasrif; Tanjung, Qadri Fauzi
Journal of Society Medicine Vol. 3 No. 8 (2024): August
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i8.159

Abstract

Introduction: The act of intubating with an endotracheal tube is a definitive airway management technique that provides maximal protection against the occurrence of aspiration of stomach contents or fluids. Some studies recommend the use of a head pillow to improve the laryngoscopic view by enhancing the occipito-atlanto-axial angle and enlarging the submandibular space. The aim of this study was to find out comparison of the level of difficulty of intubation in intubation techniques with and without the use of pillows. Methods: The design of this study was a randomized cross-sectional study with two research groups conducted to compare the difficulty levels of intubation using the technique with and without a pillow. Results: Patients without a pillow often required a little assistance during intubation, while the majority of patients using a pillow were easily intubated. However, no significant difference was found between the two groups (p>0.05). Patients intubated without a pillow had an average score of 15.9±1.6, while those intubated with a pillow had an average score of 10.8±1.8, showing a significant difference between the two groups (p<0.05). Using the Cormack-Lehane score, most patients without a pillow were at grade 2, while the majority of patients with a pillow were at grade 1. A significant difference was found between the two groups (p<0.05). Conclusion: Patients intubated without a pillow often required a little assistance, while the majority of patients intubated with a pillow were easily intubated; however, no significant difference was found between the two groups (p>0.05).
Perbandingan Kadar Interleukin-6 antara Pemberian Kombinasi Fentanil dan Midazolam Kontinyu dengan Deksmedetomidin Kontinyu pada Pasien Pascaoperasi Kraniotomi di Ruang ICU Munawar, Riza; Irina, Rr Sinta; Hamdi, Tasrif
Jurnal Neuroanestesi Indonesia Vol 12, No 3 (2023)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v12i3.557

Abstract

Latar Belakang dan Tujuan:Pembedahan kraniotomi dapat meningkatkan respon inflamasi tubuh akibat memprovokasi respon stres neuroendokrin. Interleukin-6 adalah salah satu parameter inflamasi memiliki hubungan yang erat pada inflamasi pasca operasi kraniotomi. Kombinasi fentanil dengan midazolam dan deksmedetomidin sebagai obat analgesia memiliki peran menghambat regulasi inflamasi sehingga bisa mengurangi pelepasan mediator inflamasi termasuk Interleukin-6. Tujuan penelitian untuk memperoleh hasil perbandingan pemberian kombinasi fentanil dengan midazolam dan deksmedetomidin terhadap kadar interleukin-6 pada pasien pasca kraniotomi di ruang ICUSubjek dan Metode:Penelitian menggunakan uji klinis double-blind randomized controlled trial (RCT) dengan 32 subjek penelitian yang setelah memenuhi kriteria inklusi dibagi secara acak menjadi 2 kelompok. Kelompok A mendapat kombinasi fentanil dan midazolam kontinyu dan kelompok B mendapat deksmedetomidin kontinyuHasil:Terdapat penurunan nilai rata-rata kadar interleukin-6 pada kelompok pemberian kombinasi fentanil dengan midazolam dan kelompok pemberian deksmedetomidin, namun secara statistik tidak memberikan nilai yang signifikan antara kedua kelompokSimpulan:Pemberian kombinasi fentanil dengan midazolam dan deksmedetomidin memberikan efek sebanding dalam menurunkan kadar Interleukin-6.Comparison of Interleukin-6 Levels between Continuous Combination of Fentanil and Midazolam with Dexmedetomidine Continuity in Postoperating Patients Craniotomy in ICUAbstractBackground and Objective: Craniotomy surgery can increase the body's inflammatory response by provoking a neuroendocrine stress response. Interleukin-6 as one of the inflammatory parameters has a close relationship with inflammation after craniotomy surgery. Combination fentanyl with midazolam and dexmedetomidine as anelgesia drugs have the role of inhibiting inflammatory regulation to reduce the release of inflammatory mediators including Interleukin-6. The aim of this study to compare the results of Combination fentanyl with midazolam and dexmedetomidine administration on interleukin-6 levels in post-craniotomy patients in the ICU room.Subjects and Methods: This study is an experimental study with The Pretest-Posttest Control Group Design, with a double blind randomized controlled trial (RCT) clinical trial where in this study two groups were divided. After obtaining approval from the Ethics Committee of the Faculty of Medicine, University of Sumatera Utara Medan, 32 research samples were collected, which after meeting the inclusion criteria were randomly divided into 2 groups. Group A received a combination of fentanyl and midazolam and group B received dexmedetomidine. The data obtained were tested using SPSS.Results: There was a decrease in the mean value of interleukin-6 levels in combination fentanyl with midazolam administration group and the dexmedetomidine administration group, but statistically did not provide a significant value between the two groups.Conclusion: Combination fentanyl with midazolam and dexmedetomidine administration have comparable effects in reducing Interleukin-6 levels.
Pelatihan Penanganan Cardiac Arrest (Henti Jantung) dengan Menggunakan Metode Bantuan Hidup Dasar (BHD) Bagi Pengemudi Ojek Online Se Kota Medan Siahaan, Dwi Lunarta D. S.; Sinatra, Jadeny; Nazma, Diani; Lubis, Andriamuri P.; Tanjung, Qodri F.; Sitepu, John Frans; Hamdi, Tasrif; Hamdani, Irfan; Chalil, M. Jalaluddin A.; Yunafri, Andri; Irina, Sinta; Zainumi, Cut M.; Fadinie, Wulan; Silaen, Ester L. R.; Simbolon, Boyke M.; Siahaan, Jekson M.; Lim, Hadyanto; Anto, Endy Juli; Tobing, Paul S. M. L.; Rimbun, Surjadi; Hutasoit, Eka Samuel P.; Tambunan, Ronald T. H.; Tarigan, Juliyanti; Stephanie S., Kezia; Natalie S., Karen
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 4 No 2 (2024): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol4No2.pp188-193

Abstract

Cardiac Arrest is the leading cause of death in the world including Indonesia, which can occur anytime and anywhere. The causes vary, ranging from fatigue, and underlying health conditions, to traffic accidents. Basic Life Support (BLS) is the initial step that can be taken to restore respiratory and circulatory function in individuals experiencing respiratory or cardiac arrest. It is important for online motorcycle taxi drivers to possess these skills, as they often spend time on the road and interact with various people in different situations. Perhimpunan Dokter Spesialis Anesthesiology dan Terapi Intensif (PERDATIN) North Sumatra Branch concluded a series of Kursus Penyegar dan Penambah Ilmu Anestesia (KPPIA) by providing basic life support training to 521 public transport or online motorcycle taxi drivers in the city of Medan on September 29, 2024. Held at the Gedung Serba Guna of the North Sumatra Provincial Government, the participants were divided into 52 groups guided directly by anesthesiologist specialists as instructors. By providing this education and training, they can be better prepared to face emergency situations on the road, thereby enhancing safety and service for passengers
PERBANDINGAN FLUOKSETIN 20 MG DENGAN AMITRIPTILIN 12,5 MG SEBAGAI ADJUVAN KOMBINASI PARASETAMOL DAN MORFIN DALAM MENGURANGI NYERI PADA PASIEN NYERI KANKER Ramud, Samawi Husein; Hamdi, Tasrif; Bangun, Chrismas Gideon; Yunanda, Yuki
Jurnal Anestesi Perioperatif Vol 12, No 3 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v12n3.3628

Abstract

Data WHO menunjukkan bahwa 30–40% pasien kanker mengalami nyeri sedang atau berat. Empat kelas obat antidepresan dapat dipakai dalam pengobatan nyeri neuropatik. Penelitian ini bertujuan untuk mengetahui perbandingan fluoksetin 20 mg dengan amitriptilin 12,5 mg sebagai adjuvant kombinasi parasetamol 1000 mg dalam mengurangi gejala nyeri pada pasien nyeri kanker. Penelitian dilaksanakan sejak Juli–September 2023 di klinik nyeri Rumah Sakit Umum Pusat Haji Adam Malik Medan. Penelitian ini adalah uji klinis acak tersamar. Sebanyak 40 subjek dibagi dalam 2 kelompok. Kelompok A (n=20) mendapat fluoksetin, morfin dan parasetamol, sedangkan kelompok B (n=20) mendapat amitriptilin, morfin dan parasetamol. Skor nyeri pada subjek diukur dengan menggunakan PainDETECT. Data dianalisis secara univariat dan bivariat. Data bivariat dianalisis dengan uji Chi-Square, T-Test Independent, T-Test Paired dan Mann-Whitney. Terdapat penurunan skor numeric rating scale dan PainDETECT yang signifikan antara sebelum dan setelah pemberian fluoksetin maupun amitriptilin dengan nilai p<0,05. Kelompok fluoksetin maupun amitriptilin dapat menurunkan skor numeric rating scale dan PainDETECT secara statistik, akan tetapi tidak bermakna secara klinis.
Pendekatan Anestesi pada Bedah Tulang Belakang Ghozali, Imam; Hamdi, Tasrif; Ayu Assyifa Hamka Dinata
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1139

Abstract

Spinal anesthesia is performed by injecting local anesthetic into the cerebro-spinal fluid. An anesthesiologist's adequate knowledge of anatomy, physiology, and pharmacology will make anesthesia safe and satisfactory for the patient, surgeon, and anesthesiologist. Spinal anesthesia is now often used in spinal surgery. The advantages of using this technique are a lower postoperative pain scale, minimizing the effects of postoperative nausea and vomiting, a shorter procedure, and high patient satisfaction. The first case was Mr S aged 55 years with a diagnosis of low back pain and compression of lumbar vertebra 4, lumbar 5 and sacrum 1 undergoing laminectomy, decompression and biopsy. The second case, Mrs. NH, aged 46 years, was diagnosed with ASIA 3 spinal cord syndrome and compression fracture of the T 10-11 vertebra, undergoing thoracic fusion and laminectomy surgery. The third case, Mrs. H, aged 53 years, was diagnosed with T10-11 tuberculous spondylitis who underwent laminectomy, thoracolumbar fusion and biopsy. Anesthesia for the first case (Mr. S) and the second case (Mrs. NH) used Single-Shot Anestesi Spinal Segmental Thoracic atau Thoracic Spinal Anesthesia (TSA). Meanwhile, the anesthesia for the third case (Mrs H) used the Two Stabbing Techniques.
Comparison of The Effectiveness Between Fentanyl and Ketamine as Adjuvant Epidural Analgesia with Ropivacaine In Post Operation of The Lower Extremity Pratama, Mhd. Rizki; Ihsan, Mhd.; Hamdi, Tasrif; Eyanoer, Putri Chairani
JAI (Jurnal Anestesiologi Indonesia) Vol 17, No 1 (2025): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.64228

Abstract

Background: One typical side effect that frequently follows surgery is pain. Lower limb surgery procedures can cause tissue and nerve damage. When compared to systemic opioids, epidural analgesia provides better postoperative analgesia. Adjuvants extend and intensify sensory blockage, which increases the effectiveness of local anesthesia. They also cause the dose of local anesthetic drugs to be reduced.Objective: To determine the comparative effectiveness of adjuvant fentanyl compared with ketamine and ropivacaine as adjuvant epidural analgesia in post-lower extremity surgery patients.Methods: The purpose of this randomized controlled experiment is to compare the efficacy of ketamine and fentanyl as adjuvant epidural analgesia in postoperative lower extremities when combined with ropivacaine. In this study, two groups of patients were given epidural anesthesia: the first group received ropivacaine 0.25% with 125 mcg of fentanyl adjuvant, while the second group received ropivacaine with 0.25% with ketamine 10 mg. The double-blind technique was used to select a total sample of 29 individuals from each group based on inclusion and exclusion criteria. The assessment of pain scores, hemodynamics, treatment-related side effects, and bromage scores was used to test both groups.Result: The T5 assessment showed a substantial difference in the pain scores at rest. With a total of 14 side effects, blood pressure and pulse rate fluctuations were the most common, accounting for 20% of the side effects. Despite this, patients in the ropivacaine + ketamine adjuvant group continued to experience hemodynamic stability and comfort. There were two side effects in the fentanyl combination group, with nausea being the most common. Between the therapy groups, there was no difference in the recovery of the bromage score (p>0.05).Conclusion: Ropivacaine-ketamine has favorable effectiveness as an analgesia adjuvant compared to ropivacaine-fentanyl.
Comparison of Fluoxetine (20 Mg) and Amitriptyline (12.5 Mg) As Adjuvants for The Combination of Paracetamol and Morphine in Cancer Patients' Pain Relief Ramud, Samawi Husein; Hamdi, Tasrif; Bangun, Chrismas Gideon; Yunanda, Yuki
JAI (Jurnal Anestesiologi Indonesia) Vol 17, No 1 (2025): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.59070

Abstract

Background: Pain is one of the most common symptoms in cancer which affects 30–50% of patients on average and rises to 70–90% in cases of advanced disease. As cancer advances, so does the frequency of discomfort associated with the illness. When cancer is detected in its terminal stage, 30–40% of patients report experiencing moderate pain, and 60–100% report experiencing severe pain. Tricyclic antidepressants (TCAs), selective serotonin and norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSRIs), and monoamine oxidase inhibitors (MAOIs) are the four families of antidepressant medications that have been investigated for use in the treatment of neuropathic pain.Objective: This research was conducted at the pain clinic of Adam Malik Hospital, this study intends to compare the effectiveness of fluoxetine with amitriptyline as an adjuvant to the combination of paracetamol and morphine in reducing pain symptoms in cancer patients.Methods: This study was designed as a randomized, double-blind clinical experiment. The study was carried out in 2023 between July and September. Two groups of forty research participants receiving outpatient care at the pain clinic were formed. Fluoxetine, morphine, and paracetamol were administered to group A (n = 20), whereas amitriptyline, morphine, and paracetamol were administered to group B (n = 20). PainDETECT was used to measure the subjects' pain scores. Both univariate and bivariate data analysis was done. The Chi-Square test, Independent T-test, Paired T-test, and Mann-Whitney were used to examine the bivariate data.Result: The delivery of amitriptyline and fluoxetine resulted in a substantial reduction in PainDETECT scores, with a p-value of less than 0.05.Conclusion: This study show that PainDETECT score was statistically reduced in both the fluoxetine and amitriptyline groups but the reduction was not clinically meaningful because the target score drop was less than 4 on a scale of 0–10, or a 50% reduction in pain.
Co-Authors Akim, Mhd Albar, Husnul Fuad Ayu Assyifa Hamka Dinata Bangun, Chrismas Gideon Bisono, Luwih Chalil, M. Jalaluddin A. Christine Christine Diani Nazma Eka Roina Megawati, Eka Roina Endy Juli Anto Fadinie, Wulan Fathia Meirina, Fathia Fithria Aldy Hadyanto Lim Hanafie, Achsanuddin Hanif, Raisa Syifa Hanim, Saodah Harahap, Awi Tifani M Harahap, Awi Tifani Mayandisa Harahap, Awi TM. Hutasoit, Eka Samuel P. Ihsan, Mhd Ihsan, Mhd. Imam Ghozali Irfan Hamdani, Irfan Irina, Rr Sinta Irina, Sinta Kadri, Alfansuri Kemalasari, Nadia Lubis, Andriamuri P. Lubis, Andriamuri Primaputra Mastari, Ekawaty S. Muhammad Ihsan Muhammad Ramadhan Munawar, Riza Nasution, Siti Saidah Natalie S., Karen Nurchotijah, Nurchotijah Prabowo, Haryo Pratama, Mhd. Rizki Putri Chairani Eyanoer, Putri Chairani Qadri Fauzi Tanjung Ramud, Samawi Husein Rendi Sidiq Ricardo, Dion Rimbun, Surjadi Rina Amelia Rizone, Alifya Shifwah Saputra, Firdaus Siahaan, Dwi Lunarta D. S. Siahaan, Jekson Martiar Sibarani, Nicholas Hamonangan Silaen, Ester L. R. Silaen, Ester Lantika Simamora, Fareza Rifki Simbolon, Boyke M. Sinaga, Ade Sinaga, Ade Putra Fratama Sinatra, Jadeny Sitepu, John Frans Stephanie S., Kezia Tambunan, Ronald T. H. Tanjung, Qodri F. Tarigan, Juliyanti Tobing, Paul S. M. L. Umar, Nazaruddin wicaksono, desmiko haryo YUNAFRI, ANDRI Yunanda, Yuki Yusmaidi, Yusmaidi Zainumi, Cut M. Zainumi, Cut Meliza