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All Journal eJournal Kedokteran Indonesia Jurnal Penyakit Dalam Indonesia
Aida Lydia
Divisi Ginjal Hipertensi, Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Indonesia/RSUPN Dr. Cipto Mangunkusumo, Jakarta
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Faktor-Faktor yang Memengaruhi Kualitas Hidup Pasien Gagal Jantung Kronik Fraksi Ejeksi Terjaga (HFpEF) Rawat Jalan di RSUPN Dr. Cipto Mangunkusumo Pratama, Derin Anugrah; Nasution, Sally Aman; Muhadi, Muhadi; Mansjoer, Arif; Alwi, Idrus; Purnamasari, Dyah; Lydia, Aida; Tahapary, Dicky Levenus
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 1
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Introduction. The prevalence of heart failure in Indonesian adults is 1.5%, at least half of which categorized as heart failure with preserved ejection fraction (HFpEF). Quality of life assessment plays an important role in the management of heart failure, one of the tools widely used is the Minnesota Living with Heart Failure (MLHF) questionnaire. In Indonesia, there is still no data regarding risk factors that affect the quality of life of HFpEF patients. This study aimed to determine the quality of life profile of HFpEF patients and the relationship between the risk factors (age, hypertension, DM, smoking, and obesity) on the quality of life of HFpEF patients. Methods. A cross-sectional study was conducted. Data was collected from adult HFpEF (based on echocardiography in the last 6 months) patients (>18 years old) who visited the Cardiology Clinic at Cipto Mangunkusumo Hospital from January 2022 to December 2023. Quality of life was measured using the MLHF questionnaire. Bivariate analysis was performed to find the relationship between risk factors (age, gender, hypertension, DM, smoking, and obesity) and patients’ quality of life. Multivariate analysis was performed for hypertension, DM, gender, and age variables. Results. Out of 206 subjects, 72.33% of patients were dominant in the physical domain items, and 27.67% of patients were dominant in the emotional domain items. The majority of patients dominant in physical items had overall good quality of life. The majority of patients dominant in emotional items also had good quality of life. No significant relationship was found between the dominant domain item and the quality of life in HFpEF patients. We also found that there was no significant relationship between socio-demographic factors and risk factors for dominant domain items. However, there was a significant relationship between age (p=0.005), gender (p=0.001), and smoking history (p=0.001) with the quality of life in HFpEF patients. Adult patients had a poorer quality of life compared to elderly patients (OR= 0.33 [95% CI 0.17-0.66]). No significant relationship was found between hypertension, diabetes mellitus, dyslipidemia, and obesity with the quality of life in HFpEF patients. Conclusions. There is a statistically significant relationship between age, gender, and smoking history with the quality of life in HFpEF patients. Meanwhile, there is no significant relationship between hypertension, diabetes mellitus, and obesity with the quality of life in HFpEF patients.
Faktor-Faktor yang Berhubungan dengan Kualitas Hidup Pasien Geriatri yang Menjalani Hemodialisis Mohammad, Nurhidayat; Soejono, Czeresna Heriawan; Lydia, Aida; Rinaldi, Ikhwan; Syafiq, Muhammad; Wardoyo, Elizabeth Yasmine
Jurnal Penyakit Dalam Indonesia
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Introduction. The decline in quality of life among geriatric patients undergoing hemodialysis has a negative impact on treatment adherence, physical functioning, dietary patterns, and mortality. This study was conducted to assess the quality of life of geriatric hemodialysis patients and its association with comorbidities, functional status, frailty, sarcopenia, nutritional status, depression, hemoglobin levels, hemodialysis vintage, vascular access, and hemodialysis adequacy. Methods. This study employed a cross-sectional design with primary data collection. Consecutive sampling was used to recruit participants. The study was conducted at the hemodialysis units of Cipto Mangunkusumo National General Hospital (RSCM), Persahabatan National General Hospital (RSP), and Fatmawati National General Hospital (RSF) from June 2024 to August 2024. The inclusion criteria were patients aged ≥60 years undergoing maintenance hemodialysis. Exclusion criteria were unstable clinical condition, cognitive or mental impairment, and refusal to participate. Quality of life was assessed using the EQ-5D-5L instrument. Data on medical history and laboratory findings were obtained from hospital medical records. Bivariate analysis was performed using the Mann–Whitney U test for comorbidities, sarcopenia, depression, hemoglobin level, vascular access, and dialysis adequacy; the Kruskal–Wallis test for frailty, functional status, and nutritional status; and Spearman’s correlation for hemodialysis vintage. Multivariate analysis was conducted using linear regression to identify factors associated with reduced quality of life. Results. A total of 124 subjects (mean age 67 years) were included in this study. The mean EQ-5D-5L index score was 0.76 (IQR 0.63–1.00), while the mean VAS score was 70. The majority of subjects (75%) reported no difficulties in self-care or daily activities. Functional status (p < 0.0001) and depression (p < 0.002) were significantly associated with the quality of life in geriatric patients undergoing hemodialysis, with an adjusted R² value of 0.642. Conclusions. Geriatric patients undergoing HD at RSCM, RSP, and RSF had an average EQ-5D-5L index score of 0.76 (out of 1.000), and 75% of the patients reported no issues with self-care and daily activities. Functional status and depression have been proven to play a significant role in determining their quality of life.
Co-Authors Ailinda Theodora Tedja, Ailinda Theodora Alvina Widhani, Alvina Arief Pattiiha Arif Mansjoer Aulia Rizka, Aulia Ayatullah Khomaini Ayatullah Khomaini Cleopas Martin Rumende Czeresna Heriawan Soejono Desi Salwani, Desi Dharmeizar Dharmeizar Dicky Levenus Tahapary Donnie Lumban Gaol Donnie Lumban Gaol Dono Antono Dwi Oktavia Dyah Purnamasari Dyah Purnamasari E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Endang Susalit Endang Susalit Esthika Dewiasty Esthika Dewiasty, Esthika Fahmi Razi Darkuthni Farissa Farissa Fify Henrika, Fify Gaol, Donnie Lumban Ginova Nainggolan Ginova Nainggolan Ginova Nainggolan Grecia Rachmaningrum Idrus Alwi Ika Prasetya Wijaya Ikhwan Rinaldi Lusiani Lusiani Maruhum B.H. Marbun Meilania Saraswati Mohammad, Nurhidayat Muhadi Muhadi, Muhadi MUHAMMAD SYAFIQ Muhammad Yamin Muhammad Yamin Murdani Abdullah Murdani Abdullah Murdani Abdullah Panggabean, Marulam MP Pattiiha, Arief Pratama, Derin Anugrah Pringgodigdo Nugroho, Pringgodigdo Rachmaningrum, Grecia Riadi Wirawan Rino A Gani Rino A Gani Sally Aman Nasution Sally Aman Nasution, Sally Aman Saraswati, Mita Hafsah Siti Setiati Siti Setiati Siti Setiati Siti Setiati Siti Setiati Suhardjono Suhardjono Suhardjono Suhardjono Tities Anggraeni Indra Tities Anggraeni Indra, Tities Anggraeni Tunggul Diapari Situmorang Vidhia Umami Vidhia Umami, Vidhia Wardoyo, Elizabeth Yasmine