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All Journal JIKA Prosiding Workshop dan Seminar Nasional Farmasi (WSNF) Pharmacon: Jurnal Farmasi Indonesia
vonny kurnia utama
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Identifikasi Kandungan Hidrokuinon Dalam Krim Pemutih Wajah yang Beredar di Pasar Kodim Pekanbaru Dengan Metode Kromatografi Lapis Tipis (KLT) vonny kurnia utama; Putri Hananda
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 2 (2023): Volume 1 Nomor 2 Juni 2023
Publisher : LPPM Universitas Abdurrab

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Abstract

Facial whitening cream is included in cosmetic preparations that are used to beautify oneself. Hydroquinone is a hazardous substance which is prohibited for use in cosmetic preparations. Based on BPOM regulations, hydroquinone is included in the class of hard drugs and must be used with a doctor's prescription. The purpose of this study was to determine whether or not hydroquinone was present in face whitening creams sold at the Pekanbaru Kodim Market using the Thin Layer Chromatography method, with the principle of Thin Layer Chromatography, namely the improvement of multi-component compounds using two phases, namely the stationary phase and the mobile phase. The stationary phase used was silica gel GF 254 nm and the mobile phase used was toluene and glacial acetic acid (8:2). From the results of this test, the standard Rf value of hydroquinone was 0.41 with the Rf value of sample 1, which was 0.42, the Rf value of sample 2, which was 0.43, the Rf value of sample 3, which was 0.40 and the Rf value of sample 4, which was 0.41. these results show that even the standard hydroquinone Rf value is the same or almost the same as the sample solution value of not more than 0.05. From this test, it was concluded that even all the samples tested tested positive for hydroquinone, which was indicated by the presence of purple blotches parallel to the sample tested with the hydroquinone standard, and the Rf value of the sample and standard obtained was not more than 0.05.
Efek Penambahan Minyak Jahe Sebagai Antioksidan Alami Dalam Mempertahankan Stabilitas Minyak Ikan Patin (Pangasius hypophthalmus) Yan Hendrika; Azlaini Yus Nasution; Vonny Kurnia Utama; Fatiha Ulfa
Prosiding Workshop dan Seminar Nasional Farmasi Vol. 1 (2022): Prosiding Workshop dan Seminar Nasional Farmasi 2022
Publisher : Program Studi Farmasi Fakultas MIPA Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/WSNF.2022.v01.i01.p13

Abstract

Ikan patin (Pangasius hypopthalamus) merupakan salah satu komoditas unggulan di Provinsi Riau dengan kandungan minyak yang tingga sehingga berpotensi untuk diekstrak menjadi sumber asam lemak yang bisa bermanfaat bagi kesehatan. Penambahan antioksidan mampu menghambat kerusakan asam lemak pada minyak ikan patin. Tujuan dari penelitian ini adalah untuk mengetahui kualitas minyakikan patin setelah penambahan minyak jahe sebagai antioksidan alami. Metode yang digunakan adalah metode titrasi untuk menentukan angka peroksida dari minyak ikan patin setelah penambahan minyak jahe dibandingkan dengan penambahan antioksidan alami TBHQ setelah penyimpanan selama 0, 7, dan 14 hari. Hasil yang diperoleh dari pengujian angka peroksida untuk minyak patin dengan penambahan minyak jahe untuk hari ke 0, 7, dan 14 adalah 1,58 meq/kg; 1,58 meq/kg dan 2,18 meq/kg. Sedangkan hasil yang diperoleh dari pengujian angka peroksida minyak ikan patin dengan penambahan antioksidan sintetik TBHQ untuk hari ke 0, 7, dan 14 adalah 0,90 meq/kg; 1,88 meq/kg; dan 2,11 meq/kg. Berdasarkan hasil yang diperoleh dapat disimpulkan angka peroksida minyak ikan patin yang disimpan selama 0, 7 dan 14 hari memenuhi persyaratan menurut Internasional Fish Oil Standard (IFOS) yaitu < 3,75 meq/kg.
The Potential UV-B Filter of Gel Preparation Containing Ethanol Extract of Bidara Arab Leaf (Ziziphus spina-christi) Cultivated in Indonesia Mardhiyani, Dini; Aswatul Ulya; Eni Yanti Wulan Desri; Gendis Purno Yudanti; Muslim Suardi; Vonny Kurnia Utama; Kony Putriani; Isna Wardaniati
Pharmacon: Jurnal Farmasi Indonesia Volume 22, No 1 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i1.7487

Abstract

Bidara arab leaf (Ziziphus spina-christi) contains flavonoids, saponins, triterpenoids, alkaloids, steroids, and lipids that may act synergistically as natural UV filters. Flavonoids are highlighted for their ability to absorb UVA and UVB light, while other compounds may enhance photoprotection. Previous studies reported that its ethanol extract contains 1.53% flavonoids and exhibits strong antioxidant activity (LC₅₀ = 90.96 ppm). To formulate gel preparations containing Bidara Arab leaf ethanol extract and evaluate their physicochemical properties, sun protection factor (SPF), and photoprotective efficacy against UV-B–induced erythema. The extract was incorporated into gel at concentrations of 2.5% (F1), 5% (F2), and 10% (F3). Physicochemical tests included organoleptic assessment, pH, viscosity, and spreadability. In vitro SPF was determined using UV-Vis spectrophotometry. In vivo testing involved UV-B–irradiated mice, and erythema was scored to assess protection. All gels met standard parameters (pH 5.34–6.51; viscosity 10.352–15.459 cP; spreadability 5.2–5.8 cm). SPF values were 19.26 (F1), 20.22 (F2), and 20.50 (F3), indicating medium UV-B protection. Erythema scores in all extract-treated groups were 0, with erythema areas of 0.50 mm², 0.38 mm², and 0.19 mm², respectively—significantly lower than in the blank gel (3.96 mm²) and untreated control (7.51 mm²) (p<0.01). Bidara arab leaf extract gel (2.5–10%) shows medium SPF protection and effectively prevents UV-B–induced erythema in mice. These findings support its potential as a natural sunscreen agent.
Co-Authors Aswatul Ulya Eni Yanti Wulan Desri Fatiha Ulfa Gendis Purno Yudanti Isna Wardaniati Kony Putriani Mardhiyani, Dini Muslim Suardi Nasution, Azlaini Yus Putri Hananda Yan Hendrika