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Hubungan Berat Badan dan Kadar Kolesterol Darah Tikus Putih (Rattus Norvegicus) setelah diberikan Diet Tinggi Lemak Thatit Nurmawati
Journal of Ners and Midwifery Vol 3 No 3 (2016)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v3i3.ART.p202-206

Abstract

Cholesterol is an essential substance for the body. The role of cholesterol as material hormones, cell membranare needed by the body. This conditionchanges into a distrubtion if the cholesterol levels in the blood increase. Weight becomes one of this trigger. The consumption of high-fat foods increase weight which resulting in the increase of cholesterol cases. The purpose of this study was to determine the level of correlations between weight and cholesterol levels after being given a high-fat diet.The study used rats (Rattus norvegicus) sex male, 16 rats with age between 1-2 months. Rats weight range between 100-150 gr and in healthy conditions. The giving of high-fat diet were in the form of chicken feed, duck eggs, goat oil, lard and flour for 8 weeks. The data measurement done by scales and measuringcholesterol levels through the end of the tail by means of easy touch. The data analysis were done to understand level of correlation between variables. The presentation of the data used tables. The results showed body weight of rats did not change after administration of a high-fat diet. The cholesterols levels of the subjects were high. Theadministration of high-fat diet from egg yolk dan goat oilcould increase the level of cholesterol. There was a correlation between weight and cholesterol levels after being given a high-fat diet (p <0.5). It was needed to repeatthe measurements to determine changes in cholesterol levels and other factors that affect thigh blood to cholesterol levels.
Efektifitas Rebusan Wortel (Daucus Carota. L) terhadap Penurunan kadar Kolesterol Darah pada Tikus Putih (Rattus Norvegicus) Misnanto Misnanto; Thatit Nurmawati
Journal of Ners and Midwifery Vol 3 No 3 (2016)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v3i3.ART.p286-291

Abstract

Hypercholesterolemia is a disease of cholesterol metabolism disorder caused by high blood cholesterol. Chemical treatment is reported to have side effects in the long term. The purpose of this study was to determine the effectiveness of carrot stew to decrease cholesterol levels in hypercholesterolemic of rats.The design of this study used experimental randomized control-group pretest - post test design. The samples were divided into control and treatment groups, each group consisted 8 rats. The treatment used a carrot stew with 1.25cc dose and control with medication simvastatin 0144 cc dose was given every morning for 3 days. The measurement of the cholesterol levels used Touch Essey data analysis by Wilcoxon and Mann-Whitney. The study started on May 15th - July 22, 2015.The results of the study showed the cholesterol control group decreased 12.5% (P = 0.069> á = 0.05) in the treatment group and 50% (P = 0.716), On the statistical test showed no effect of carrot stew on blood cholesterol levels. While the results of the effect between treatment and control group (P = 0528> á = 0.05).Carrots with beta-carotene could lower cholesterol levels in the blood, and could prevent the oxidation of Low Dencity Lipoprotein (LDL). The absorption of beta-carotene was better when boiled in temperatures between 60-100 ° C.
Studi Respon Fisiologis dan Kadar Gula Darah pada Tikus Putih (Rattus Norvegicus) yang Terpapar Streptozotocin (STZ) Thatit Nurmawati
Journal of Ners and Midwifery Vol 4 No 3 (2017)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v4i3.ART.p244-247

Abstract

Diabetes mellitus (DM) is a metabolic disorder with symptoms of polydipsi, polyuria, polyphagia, weight loss and tingling. The incidence of DM increased with the number of patients with type 2 DM more than type1 DM. Insulin resistance and deficiency is characteristic of type 2 diabetes. Streptozotocin (STZ) as a DM inducer model is better than alloxan by altering the physiological pancreas. The purpose of this study was to determine the physiological response and blood sugar levels of mice after exposure to STZ. Descriptive research design with the study subjects of 16 white wistar strains (Rattus norvegicus).  STZ is given 40mg / kg  BW for 3 days. Data collection is done 2 days after STZ last gift. Blood glucose  levels are obtained from  the end of the tail while the heart rate is measured  using a modified stethoscope. Data is presented in the mean ± SD. The results showed heart rate 500 ± 59.32 / min, weight 292,5 ± 65,26 (gr) and blood glucose content 237 ± 102.5 ml /dl. STZ responded to ratts resulting in physiological changes. Histologic observation of pancreatic cells is needed to determine the damage caused by STZ . Needed longer observation to see the response of ratts further.
Efektifitas Pendidikan Kesehatan dengan Metode Ekspositori tentang Meal Planning terhadap Pola Makan Pasien DM Tipe 2 Thatit Nurmawati; Yeni Kartika Sari; Mitria Setyaningsih
Journal of Ners and Midwifery Vol 5 No 3 (2018)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v5i3.ART.p257-262

Abstract

Penderita Diabetes Mellitus (DM)  memiliki resiko komplikasi dan terjadi kematian. Namun pengelolaan penderita DM tipe II belum dilaksanakan secara optimal dan terpadu. Pendidikan kesehatan metode ekspositori terdiri dari tiga tahap yaitu penjelasan materi, tanya jawab dan penugasan tentang meal planning dapat diupayakan untuk mengatasi kasus DM dari pola makannya . Penelitian ini bertujuan mengetahui pengaruh pendidikan kesehatan metode ekspositori tentang meal planning terhadap pola makan penderita DM tipe II. Desain penelitian menggunakan quasy experiment dengan non equivalent control group design. Populasi penderita DM Tipe II sejumlah 210 orang. Tehnik sampling yang digunakan dalam penelitian ini adalah purposive sampling. Sampel dibagi menjadi kelompok perlakuan dan kelompok kontrol dengan jumlah masing-masing 20 orang Pengumpulan data dilakukan di wilayah Puskesmas Boro Kecamatan Selorejo dengan mengidentifikasi responden dan memberikan questioner kepatuhan. Data dianalisis dengan menggunakan Wilcoxon signed rank tes. Hasil penelitian pada kelompok perlakuan menunjukkan ada pengaruh pendidikan kesehatan dengan metode ekspositori tentang meal planning pada pasien DM Tipe 2 dengan p- value 0,000. Hasil uji Mann Whitney didapatkan hasil ada perbedaan antara kelompok perlakuan dengan kelompok kontrol dengan p-value sebesar = 0,000. Metode ekspositori tentang meal planning berpengaruh terhadap pola makan penderita DM tipe II. Tenaga kesehatan dianjurkan untuk meningkatkan kegiatan pendidikan kesehatan metode ekspositori kepada penderita DM tipe II untuk memperbaiki pola makannya.
Pengaruh Pendidikan Kesehatan Metode Guidance and Counseling terhadap peningkatan Efikasi Diri (Self Efficacy) pada Pasien TBC di wilayah kerja Puskesmas Boro Elok Dwi Mamiri; Ulfa Husnul Fata; Thatit Nurmawati
Journal of Ners and Midwifery Vol 7 No 2 (2020)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v7i2.ART.p190-195

Abstract

TB Paru merupakan salah satu penyakit menular yang masih menjadi permasalahan di dunia hingga saat ini.Angka dropout dan kambuh terjadi setiap tahun dan salah satu faktor internal yang mempengaruhi yaitu efikasi diri (self efficacy) yang rendah dan untuk meningkatkannya perlu metode pendidikan kesehatan yang tepat yaitu guidance and counseling.Tujuan penelitian ini untuk mengetahuipengaruh pendidikan kesehatan Metode Guidance and Counselingterhadap peningkatan efikasi diri (self efficacy) pada pasien TBC di wilayah kerja Puskesmas Boro.Penelitian menggunakan desain penelitian quasy experiment.Populasi adalah Pasien TBC di wilayah Puskesmas Boro dan sesuai kriteria inklusi sebanyak 19 responden dengan teknik purposive sampling, pengumpulan data menggunakan kuesionerdan analisis data menggunakan uji statistik wilcoxon signed rank test. Nilai rata – rata efikasi diri sebelum intervensi 24, setelah intervensi sebesar 32,63. Peningkatan rata – rata sebelum dan sesudah intervensi sebesar 8,63. Hasil uji statistik wilcoxon signed rank test dengan α ≤ 0,05 menunjukkan bahwa nilai ρ-value sebesar 0,000. Hal ini berarti ada ada pengaruh pendidikan kesehatan metode guidance and counseling terhadap peningkatan efikasi diri pada pasien TBC. Berdasarkan hasil penelitianini maka petugas kesehatandapat mengaplikasikan metode guidance and counselinguntuk meningkatkan pengetahuan dan keterampilan serta memaksimalkan peran petugas kesehatan pada pemberian pendidikan kesehatan dalam rangka pelayanan paripurna dan menunjang kesembuhan pasien TBC dengan meningkatkan efikasi diri (self efficacy) pasien. Pulmonary TB is one of the infectious diseases that still exist until now. The number of dropouts and relapses cases occurs every year. One of the internal factors that affected the case is low self-efficacy (self efficacy). Guidance and counseling method could increase the self efficacy. The purpose of this study was to determine the effectiveness of health education with Guidance and Counseling methods to the improvement of self efficacy of TB patients in working area of Boro Public Health Center. The study used quasy experiment design. The population was TB patients in working area of Boro Pulic Health Center. The sample was 19 respondents with purposive sampling technique. The data collected by questionnaires and the data analysis used Wilcoxon signed rank test statistics. The average value of self-efficacy before intervention was 24, after the intervention was 32.63. The increase in the average before and after the intervention was 8.63. The result showed that ρ-value 0,000 meant that there was an effect of health education with guidance and counseling methods to the improving self-efficacy in TB patients. Based on the results of this study, health workers could apply guidance and counseling methods to the improvement of knowledge and skills and maximize the role of health workers in the provision of health education in the context of plenary service and support the recovery of TB patients by increasing patient self-efficacy.
Hubungan antara Lama Pengobatan dengan Jumlah CD4 pada Penderita HIV/AIDS yang menjalankan Program Pengobatan Antiretrovial (ARV) Thatit Nurmawati; Yeni Kartika Sari; Aprilia Putri Hidayat
Journal of Ners and Midwifery Vol 6 No 2 (2019)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v6i2.ART.p197-202

Abstract

HIV merupakan  masalah kesehatan yang mengancam Indonesia dan banyak negara di seluruh dunia. Desain penelitian yang digunakan adalah metode Cross-Sectional. Populasi dalam penelitian ini adalah penderita yang menjalankan program pengobatan antiretrovial HIV/AIDS di Poli Cendana RSUD Ngudi Waluyo Kabupaten Blitar. dengan rata- rata kunjungan pasien adalah 40 orang perminggu. Peneliti menetapkan jumlah sampel yaitu 30 orang sesuai kriteria inklusi dan ekslusi. Analisis menggunakan Spearman untuk mengetahui hubungan lama pengobatan dengan jumlah CD4. Hasil penelitian menunjukkan responden berada pada usia dalam rentang 20-30 dengan prosentase terbesar sebanyak 33,3%. Berdasarkan jenis kelamin mayoritas laki-laki sebanyak 53,3%. Hasil pendataan juga menunjukkan sebagian besar menjalakan terapi dengan pemberian Duviral dan Nevirapine pada prosentase 76,7. Responden dalam penelitian ini juga mendapat dukungan keluarga yang baik (36,6%) meskipun terdapat juga dukungan keluarga yang buruk (3,3%). Tingkat kepatuhan tinggi juga terlihat dari distribusi responden yang menunjukkan prosentase sebesar 43,3% dan masih ada responden yang memiliki kepatuhan rendah. Hasil analisis menunjukkan tidak ada hubungan antara lama pengobatan dengan CD4 (p=0.007). Perlu evaluasi perhitungan jumlah CD4 sebelum pemberian ARV.
Faktor yang Berhubungan dengan Pengetahuan Orang Tua tentang Stunting pada Balita Anita Rahmawati; Thatit Nurmawati; Liliani Permata Sari
Journal of Ners and Midwifery Vol 6 No 3 (2019)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v6i3.ART.p389-395

Abstract

Stunting masih menjadi masalah gizi anak yang utama yang dapat menimbulkan dampak besar, namun masyarakat khususnya orangtua banyak yang belum memahami stunting dengan benar. Tujuan penelitian ini adalah menganalisis faktor yang berhubungan dan yang mempunyai pengaruh paling dominan terhadap pengetahuan orang tua tentang stunting pada balita. Penelitian ini menggunakan desain crosssectional dengan populasi yaitu orangtua yang memiliki anak balita usia 0-3 tahun di Posyandu Dusun Plosoarang, Sanankulon, Kabupaten Blitar. Sampel diambil dengan purposive sampling sebanyak 20 orang dengan kriteria inklusi orang tua yang mengantar ke posyandu dan minimal berpendidikan SMP. Pengukuran data menggunakan kuesioner meliputi data pengetahuan, usia, pendidikan terakhir, pekerjaan, dan informasi yang pernah diperoleh. Analisis bivariat menggunakan koefisien kontingensi. Analisis multivariat menggunakan uji regresi logistik ganda dengan nilai signifikan α=0,05. Hasil penelitian menunjukkan faktor yang berhubungan dengan pengetahuan tentang stunting yaitu usia (p=0,017), pendidikan (p=0,043), informasi (p=0,002). Analisis uji regresi logistik menunjukkan informasi menjadi faktor yang paling dominan terhadap pengetahuan (p=0,025). Faktor yang tidak berhubungan yaitu pekerjaan (p=0,078) dan pengalaman (p=0,822). Petugas posyandu agar memberikan informasi tentang stunting saat kegiatan posyandu misalnya melalui penyuluhan atau konseling. Orang tua diharapkan agar meningkatkan pengetahuan tentang stunting dengan mencari informasi melalui berbagai media yang ada. Stunting is still a major child nutrition problem that can have a big impact. But many people especially parents do not understand about stunting correctly. The aim of this study was to analyze the factors that are related and which have the most dominant influence on parental knowledge about stunting in toddler. This study uses cross sectional design with a population that is parents who have children aged 0-3 years old at Posyandu of Plosoarang village, Sanankulon, Blitar. Sampel were taken bu purposive sampling of 20 people with the inclusion criteria of parent who took to posyandu and at least junior high school education. Data measurement using a questionnaire includes data on knowledge, age, education, employment, and information ever obtained. Bivariate analysis uses contingency coefficients. Multivariate analysis using multiple logistic regression test. The Result showed factors related to knowledge about stunting are age (p=0,017), education (p=0,043), information (p=0,002). Logistic regression analysis showed that information was the most dominant factor in knowledge (p=0,0025). Unrelated factors were work (p=0,078) and experience (p=0,822). Posyandu officers are expectedto provide information about stunting during posyandu activities and parents are expected to increase knowledge about stunting by finding information through various media.
The Effect of Yacon Leaf Powder (Smallanthus Sonchifolius) on White Rats (Rattus norvegicus) Blood Glucose Levels with High Sugar Diet Thatit Nurmawati; Sandi Alfa Wiga Arsa; Nawang Wulandari; Agus Saparudin
Journal of Ners and Midwifery Vol 8 No 2 (2021)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v8i2.ART.p217-220

Abstract

Maintaining a lifestyle can reduce the incidence of DM (diabetes mellitus). DM occurs due to insulin disorders so that blood glucose levels increase, which can lead to various complications. The management of blood glucose levels by activating the insulin function can be done by using natural ingredients such as the Yakon (Smallanthus sonchifolius) plant. Yakon leaves contain phenol which can reduce blood glucose. The design of this study was experimental with a pre-posttest approach with control-group design, using male and healthy white rats (Rattus norvegicus). Rats were divided into 3 groups, treatment dose 1, treatment dose 2 and control. The rats were given a high carbohydrate diet during 9 weeks to make the rats hyperglycemic. In the treatment group, dose 1 was 150 mg/kg BW, dose 2 was 300 mg kg BW, and was given for 3 days. The results showed that the rats in the treatment group dose 1 had decreased in the average blood sugar level of 114.10 mg / dl (p 0.002) and dose 2 was 105.27 mg / dl (p 0.005). This showed that there was an effect of treatments on blood sugar levels. The comparison results showed that there was a significant difference between the dose 1, the dose 2 group and the control (Sig. (2-tailed) = 0.001 (α) = 0.05). There was no significant difference in the treatment group dose 1 and treatment dose 2 (Sig. (2-tailed) = 0.693, (α) = 0.05). Yakon leaves can be used alternative to lower to control blood glucose levels in rats receiving a high-carbohydrate diet
Monitoring Mean Arterial Preasur (MAP) in Traumatic Brain Injury Patients during The Initial 60 Minutes of Manitol 20% Sandi Alfa Wiga Arsa; Anita Rahmawati; Thatit Nurmawati; Heni Rohmawati
Journal of Ners and Midwifery Vol 10 No 2 (2023)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v10i2.ART.p217-224

Abstract

The effect of manitol 20% on changes in blood pressure after traumatic brain injury is unknown. The purpose of this study was to analyze the differences in blood pressure before and after the administration of 20% mannitol in traumatic brain injury patients at the Intensive Care Unit. This study is a quasi experimental research which uses a pre-post test without control one group design, a method used in observational analytic techniques. The population of this study were all traumatic brain injury patients who were given a manitol infusion of 20% 100ml, with consecutive sampling technique, obtained 12 samples. With a significance threshold of p 0.05, the test was performed using the Paired T test on systolic and MAP data and the post hoc Wilcoxon test on diastolic data.   paired t-test systolic p=0.000, MAP p=0,000. Wilcoxon test diastolic p=0,002. Decreasing blood pressure 15 minutes after administration of 20% mannitol occurs because half live mannitol which lowers blood pressure and responds to decreased blood pressure autoregulation, at 30 minutes resulting in decreased intra-cranial pressure, improves cerebral perfusion and brain autoregulation that affects systemic blood pressure 60 changes in blood pressure may be due to diuresis effects. During the administration of mannitol there is a change in blood pressure that needs to be monitored
Comorbidity and Fatality Among Covid Patients: A Hospital Based-Retrospective Cohort Study Yeni Kartika Sari; Thatit Nurmawati; Joko Ivnu Santoso; Maratus Sholichah Fitriah Hajar Kusnianto
Journal of Ners and Midwifery Vol 10 No 2 (2023)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v10i2.ART.p210-216

Abstract

People with comorbid diseases have a high risk of contracting COVID-19, because the immune system has decreased, thus increasing the risk of transmission of COVID-19 and even potentially increasing the risk of fatality. This study aimed to determine the comorbidity and mortality among COVID-19 confirmed cases during May to September, 2021. The study was a retrospective cohort with secondary data from the COVID-19 with in Hospital report from May to September, 2021, with a total sample of 178. We extracted demographic and clinical data, including hospital outcomes (discharge or death). The result of the research showed that the respondents separated in to two groups, half of them are patients with comorbidity (89 patients) and the rest are patients non comorbidity. From 89 patients with comorbidity, 62 % were died and 38 % were discharged. The most comorbidites were 67,4% diabetes mellitus, 33% hypertension. The fatality rate of COVID-19 patients was 34% devided to 61,8% were comorbidity patients and 5,5% were non comorbidity. The comorbidity related to fatality rate of COVID-19 patient’s (p=0.000). It is important for society to avoid and control comorbid factors of COVID-19