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GAMBARAN MAKROSKOPIK LIMPA TIKUS (Rattus norvegicus) PADA PEMBERIAAN EKSTRAK ETANOL DAUN GINSENG (Talinum paniculatum (Jacq.) Gaertn) YANG DIINDUKSI OVALBUMIN Multazania, Multazania; sahab, Fitria; Muarsih, Ahmad Juniardhy; Ashar, Muhammad Affan; Emelda, Andi; Putra, Bayu; Santi, Irma
Makassar Pharmaceutical Science Journal (MPSJ) Vol 3 No 1 (2025)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v3i1.331

Abstract

Fameflower Leaves (Talinum paniculatum (Jacq) Gaertn) are medicinal plants that communities have traditionally used due to their active compounds, such as saponins, flavonoids, tannins, triterpenes, sterols, and polyphenols found in both the leaves and roots. This study aimed to determine the dose of ethanol extract of fameflower leaves affecting the histology of the spleen in male rats (Rattus norvegicus) following ovalbumin antigen stimulation, as well as to observe changes in the spleen tissue structure after the extract treatment. The study used 20 Wistar rats divided into four groups. The rats were first adapted for 2 weeks and then fasted for 8 hours before the treatment—a group I served as the standard control. Group II was induced with ovalbumin antigen. Groups III and IV were induced with the antigen, and the ethanol extract of fameflower leaves was administered at doses of 0.4g/kgBW and 0.8g/kgBW, respectively. The extract was administered orally for 7 days to the test animals. On day 8, the test animals were sacrificed, and their spleens were harvested for histological preparation using the Hematoxylin-Eosin staining method. Microscopic observation showed no histological damage in the spleen, such as inflammation, degeneration, congestion, hemorrhage, or necrosis. Therefore, it can be concluded that the ethanol extract of Bugis Ginseng leaves did not affect the spleen of rats at doses of 0.4g/kgBW and 0.8g/kgBW
PENYULUHAN KESEHATAN: BAHAYA ROKOK BAGI KESEHATAN DI PONDOK PESANTREN AN NAHDLAH MAKASSAR St. Maryam; Emelda, Andi; Rahmawati; Razak, Rais; Santi, Irma; Amriati, Rezki
JURNAL PENGABDIAN MASYARAKAT YAMASI Vol. 3 No. 1 (2024): Jurnal Pengabdian Masyarakat Yamasi
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jpmy.v3i1.329

Abstract

Smoking is one of the main risk factors for several chronic diseases that can result in death, so it can be a big problem for public health. Educational activities about the dangers of smoking for health were given to Aliyah students at the An-Nahdlah Islamic Boarding School in Makassar with a total of 40 participants. The aim of this activity is to increase students' awareness of the bad effects of smoking on health. This activity method begins with filling out a pre-test knowledge questionnaire about the dangers of smoking, which is then continued with counseling by the resource person and completing the post-test questionnaire again. The results of filling out the questionnaire after the counseling had increased, namely 90% of students understood the bad effects of smoking. During the counseling, students were very enthusiastic in listening to the presenters, so it is hoped that this activity will be encouraged, especially in the world of education.