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Association Between the Neutrophil-to-Lymphocyte Ratio and the Degree of Carotid Artery Stenosis Ari Bandana Tasrif; Subandi Subandi
Jurnal Ners Vol. 10 No. 2 (2026): APRIL 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i2.55126

Abstract

Ischemic stroke accounts for the majority of instances and is mostly linked to carotid artery stenosis brought on by inflammatory atherosclerosis. This study used medical record data of hospitalized ischemic stroke patients who had digital subtraction angiography (DSA) between January and August 2025. It was an analytical observational study with a cross-sectional design that was carried out at Dr. Moewardi Hospital in Surakarta from October to November 2025. Purposive sampling was used to choose samples based on inclusion and exclusion criteria; the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria were used to determine the degree of carotid stenosis; SPSS version 25 was used for statistical analysis using Pearson or Spearman correlation tests based on data distribution. Most ischemic stroke patients were male, aged 50–64 years, with diabetes mellitus and hypertension as the main comorbidities, and the majority had mild to severe carotid stenosis, while a small proportion had critical stenosis or total occlusion. While sex, age, hypertension, diabetes mellitus, and dyslipidemia did not substantially correlate with the degree of carotid artery stenosis (p above 0.05), NLR was the only predictor that did (p below 0.001). NLR was the only independent predictor that was substantially correlated with the degree of carotid artery stenosis, according to multivariate analysis using ordinal logistic regression (B was 0.227; p was 0.012). In ischemic stroke patients at Dr. Moewardi Hospital in Surakarta, NLR is substantially correlated with and an independent predictor of the degree of carotid artery stenosis.
SPINAL CORD INFARCTION AS A RARE NEUROLOGICAL COMPLICATION OF ANTERIOR STEMI FOLLOWING FIBRINOLYTIC THERAPY: A CASE REPORT Novia Heriza; Subandi
Magna Neurologica Vol. 4 No. 2 (2026): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v4i2.3378

Abstract

Background: Spinal cord infarction (SCI) is a rare cause of acute neurological deficits and an exceedingly uncommon embolic complication of acute myocardial infarction (AMI). The primary mechanism involves cardioembolism originating from a left ventricular (LV) mural thrombus. We report a rare case of SCI presenting as acute paraplegia following fibrinolysis for anterior ST-elevation myocardial infarction (STEMI). Case: A 53-year-old man presented with typical chest pain. Electrocardiography demonstrated anterior STEMI, and fibrinolytic therapy with streptokinase was administered immediately. Six hours later, he developed sudden bilateral lower-limb weakness, sensory loss from the toes to the T10 level, and urinary retention. Neurological examination showed complete paraplegia (motor strength 0/0) with loss of pain and temperature sensation below T10, while vibration and proprioception were preserved, consistent with Anterior Spinal Artery Syndrome (ASAS). Spinal magnetic resonance imaging revealed T1-hypointense and T2-hyperintense lesions in the anterior horn at the T10 level, confirming anterior spinal artery infarction. Discussion: Acute paraplegia after fibrinolysis was strongly suspected to result from an embolic shower caused by destabilization of an LV mural thrombus, leading to occlusion of the radiculomedullary artery and subsequent ASAS. Because neurological recovery is often limited, prompt anticoagulation and early rehabilitation are essential to optimize outcomes. Conclusion: SCI is a rare but serious complication of anterior STEMI associated with LV thrombus formation, which may cause cardiogenic embolism through the artery of Adamkiewicz. Clinicians should maintain a high index of suspicion for spinal cord stroke in post-STEMI patients, particularly after fibrinolytic therapy, to facilitate timely diagnosis and management.