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Association Between the Neutrophil-to-Lymphocyte Ratio and the Degree of Carotid Artery Stenosis Ari Bandana Tasrif; Subandi Subandi
Jurnal Ners Vol. 10 No. 2 (2026): APRIL 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i2.55126

Abstract

Ischemic stroke accounts for the majority of instances and is mostly linked to carotid artery stenosis brought on by inflammatory atherosclerosis. This study used medical record data of hospitalized ischemic stroke patients who had digital subtraction angiography (DSA) between January and August 2025. It was an analytical observational study with a cross-sectional design that was carried out at Dr. Moewardi Hospital in Surakarta from October to November 2025. Purposive sampling was used to choose samples based on inclusion and exclusion criteria; the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria were used to determine the degree of carotid stenosis; SPSS version 25 was used for statistical analysis using Pearson or Spearman correlation tests based on data distribution. Most ischemic stroke patients were male, aged 50–64 years, with diabetes mellitus and hypertension as the main comorbidities, and the majority had mild to severe carotid stenosis, while a small proportion had critical stenosis or total occlusion. While sex, age, hypertension, diabetes mellitus, and dyslipidemia did not substantially correlate with the degree of carotid artery stenosis (p above 0.05), NLR was the only predictor that did (p below 0.001). NLR was the only independent predictor that was substantially correlated with the degree of carotid artery stenosis, according to multivariate analysis using ordinal logistic regression (B was 0.227; p was 0.012). In ischemic stroke patients at Dr. Moewardi Hospital in Surakarta, NLR is substantially correlated with and an independent predictor of the degree of carotid artery stenosis.
SPINAL CORD INFARCTION AS A RARE NEUROLOGICAL COMPLICATION OF ANTERIOR STEMI FOLLOWING FIBRINOLYTIC THERAPY: A CASE REPORT Novia Heriza; Subandi
Magna Neurologica Vol. 4 No. 2 (2026): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v4i2.3378

Abstract

Background: Spinal cord infarction (SCI) is a rare cause of acute neurological deficits and an exceedingly uncommon embolic complication of acute myocardial infarction (AMI). The primary mechanism involves cardioembolism originating from a left ventricular (LV) mural thrombus. We report a rare case of SCI presenting as acute paraplegia following fibrinolysis for anterior ST-elevation myocardial infarction (STEMI). Case: A 53-year-old man presented with typical chest pain. Electrocardiography demonstrated anterior STEMI, and fibrinolytic therapy with streptokinase was administered immediately. Six hours later, he developed sudden bilateral lower-limb weakness, sensory loss from the toes to the T10 level, and urinary retention. Neurological examination showed complete paraplegia (motor strength 0/0) with loss of pain and temperature sensation below T10, while vibration and proprioception were preserved, consistent with Anterior Spinal Artery Syndrome (ASAS). Spinal magnetic resonance imaging revealed T1-hypointense and T2-hyperintense lesions in the anterior horn at the T10 level, confirming anterior spinal artery infarction. Discussion: Acute paraplegia after fibrinolysis was strongly suspected to result from an embolic shower caused by destabilization of an LV mural thrombus, leading to occlusion of the radiculomedullary artery and subsequent ASAS. Because neurological recovery is often limited, prompt anticoagulation and early rehabilitation are essential to optimize outcomes. Conclusion: SCI is a rare but serious complication of anterior STEMI associated with LV thrombus formation, which may cause cardiogenic embolism through the artery of Adamkiewicz. Clinicians should maintain a high index of suspicion for spinal cord stroke in post-STEMI patients, particularly after fibrinolytic therapy, to facilitate timely diagnosis and management.
Efektifitas Penyuluhan Epilepsi Terhadap Tingkat Pengetahuan Kader PMR SMA/SMK Surakarta Tentang Penyakit Epilepsi dan Penanganan Kedaruratan pada Kasus Kejang Diah Kurnia Mirawati; Pepi Budianto; Hanindia Riani Prabaningtyas; Subandi Subandi; Rivan Danuaji; Ira Ristinawati; Raden Andi Ario Tedjo; Ginong Pratidina Wijnaputri; Dhiandra Dwi Hapsari
SEMAR (Jurnal Ilmu Pengetahuan, Teknologi, dan Seni bagi Masyarakat) Vol 14, No 1 (2025): Mei
Publisher : LPPM UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/semar.v14i1.94925

Abstract

 Epilepsi merupakan salah satu penyakit saraf yang menjadi permasalahan kesehatan masyarakat global. Prevalensi epilepsi di Indoesia berdasarkan data dari Departemen Kesehatan tahun 2018 sebesar 1.8 juta. Insidensi epilepsi berkisar 50.4 per 100.000 populasi pertahun dengan 80% pasien epilepsi di dunia terjadi di negara berkembang. Penderita epilepsi sering mendapatkan stigma negatif di masyarakat. Pentingnya penyuluhan mengenai informasi terkait epilepsi pada masyarakat khususnya pada kader PMR diharapkan dapat memberikan informasi secara lebih lengkap terkait epilepsi sekaligus sebagai pemutus stigma. Penelitian ini dibuat untuk mengetahui efektivitas penyuluhan epilepsi terhadap tingkat pengetahuan kader PMR SMA/SMK Surakarta mengenai penyakit epilepsi dan penanganan kedaruratan pada kasus kejang. Penyelenggaraan penyuluhan diikuti oleh 159 responden yang berasal dari 70 SMA/SMK se-karesidenan Surakarta dengan masing-masing mengirimkan minimal 2 perwakilan PMR. Sebelum dan sesudah penyuluhan dilakukan evaluasi terkait pengetahuan peserta mengenai epilepsi melalui pretest dan posttest. Data hasil evaluasi menunjukkan adanya perbaikan pengetahuan peserta dari skor rata rata awal  74.12 menjadi 82.5. Kata kunci : epilepsi, penyuluhan, anggota PMR 
A 61-Years-Old Female with Moyamoya Syndrome: A Case Report Martha Oktavia Dewi Savitri; Azmi Farah Fairuzya; Subandi; Iqbal Imanuddin; Andry Nur Wahyu Putra Romadhoni; Tomohiro Hosoya
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.1119

Abstract

Background: Moyamoya vasculopathy (MMV), like Moyamoya disease (MMD) and Moyamoya syndrome (MMS), is a rare chronic cerebrovascular angiopathy, especially in elderly patients. The incidence onset of MMV were unique with bimodal peak age: 5-10 years old and 25-49 years old. Case: A 61-year-old-female complaint of sudden onset left-sided hemiparesis one month before admission, headache, and forgetfulness. She had history of diabetes mellitus for 3 years. Neurological physical examination found left hemiparesis with motoric strength 4/5. Laboratory findings are unremarkable. Brain MRI with contrast showed infarcts at subcortical regions. Her cerebral DSA examination suggested diffuse multiple stenosis in the anterior circulation and total occlusion of left external and internal carotid artery. “Puff of smoke” and “champagne-bottle like neck sign” were found in DSA imaging, typical signs of MMD. She received aspirin 80 mg as her secondary prevention of another stroke event.  Discussion: MMV case at elderly onset which is similar to prior small study with mean age of 60 years old. Previous study mentioned hypertension (44%) and diabetes mellitus (16%) were found in older MMD patients. Patient was given aspirin 80mg daily. Precautions in this case include taking lifelong antiplatelet, managing diabetes mellitus, and implementing lifestyle modification. This treatment approach was directed to lower concomitant risk of ischemic stroke. Conclusion: We report a case of MMV which was considered as a rare case and a cause of stroke event. The management of this case was directed to control the coexisting condition of ischemic stroke using antiplatelet drug and risk factor management.
Moyamoya Disease Involving Anterior and Posterior Circulation in Pediatric Ischemic Stroke: Rare Case Report Subandi Subandi; Lothar Matheus Manson Vanende Silalahi
Journal of Neurointervention and Stroke Vol. 1 No. 1: MAY 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.11.10

Abstract

Highlight: Moyamoya disease is one of the causes of stroke in children Moyamoya disease typically involves anterior circulation Posterior circulation may also be involved in certain cases of Moyamoya disease ABSTRACT Introduction: Ischemic stroke is frequently observed in adults but may also occur in children. Moyamoya disease (MMD) is one of the causes of ischemic stroke in children. MMD is a progressive steno-occlusive large-vessel cerebral arteriopathy. MMD was initially defined as changes in the carotid artery with an abnormal vascular network, however, the changes were also noted in posterior circulation. Case: We reported the case of a 13-year-old male with right-sided weakness persisting for over 3 years. Magnetic resonance imaging revealed cortical infarction in the left parietal lobe. Digital subtraction angiography (DSA) confirmed moyamoya disease by revealing total occlusion of the bilateral terminal internal carotid artery and bilateral posterior cerebral artery, accompanied  by a puff of smoke appearance. We treated this patient with antiplatelet therapy for secondary stroke prevention. Conclusion: MMD is one of the conditions that can cause ischemic stroke in children. The posterior circulation is another possible site of MMD manifestation, but it is mostly found in cerebral anterior circulation.