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All Journal Journal Pharmaceutical Science and Application (JPSA) Jurnal Kajian Bali Jurnal Ilmu Kefarmasian Indonesia Jurnal Ilmiah Medicamento Sevanam: Jurnal Pengabdian Masyarakat Jurnal Yoga Dan Kesehatan Open Access DRIVERset
I Gusti Agung Ayu Kartika
Yoga And Health Study Program, Faculty Of Brahma Widya, Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar, North Denpasar, Bali 80237, Indonesia
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Journal : Jurnal Ilmiah Medicamento

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Profil Fitokimia dan Aktivitas Antibakteri dari Massoia aromatic Becc., Acorus calamus L., dan Allium sativum L. terhadap Bakteri Penyebab Rinosinusitis Sugata, I Made; Darmo Suputra, I Kadek; Emy Suryanti, Putu; Juniartha, Made G.; Kartika, I Gusti Agung Ayu
Jurnal Ilmiah Medicamento Vol 9 No 2 (2023): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v9i2.5961

Abstract

Triketuka, an herb with multiple therapeutic activities, is featured in Balinese medicinal texts. This herb is composed of Massoia aromatic Becc. (masoyi), Acorus calamus L. (dringo), and Allium sativum L. (garlic). The antibacterial activity of these ingredients against bacteria causing rhinosinusitis has not been fully evaluated. Hence, this study seeks to determine the potential of these three components, especially with regards to their effectiveness against rhinosinusitis. In this research, an in vitro antibacterial test was conducted against Streptococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Pseudomonas aeruginosa. The phytochemical profile of each plant was determined using Liquid Chromatography-Mass Spectrometry. The Minimum Inhibitory Concentration value was determined by carrying out the antibacterial test via the microdilution method. The detected compounds were analyzed for their contributions through the prediction of activity spectra for biologically active substances (PASS) online and Antibac-Pred. As a result of the in vitro antibacterial test, the samples were found to have MIC > 4096 ppm against all bacteria except Massoia aromatic and Acorus calamus against Staphylococcus aureus in MIC 4096 ppm each. This discovery was further verified through PASS online and Antibac-Pred. The studies indicate that certain compounds found in the samples exhibit antibacterial activity, albeit with low efficacy against the tested bacteria. In conclusion, the plants exhibit low antibacterial potential against bacteria that cause rhinosinusitis. Further research on the combination of the three plants is required to enhance their antibacterial efficiency.
Analisis Bibliometrik Formulasi Poliherbal sebagai Afrodisiak: Tinjauan Tren Penelitian Terkini Kartika, I Gusti Agung Ayu; Nugraha, Iwan Saka; Mahardika, Ida Bagus Putra; Suryani, Suryani
Jurnal Ilmiah Medicamento Vol 11 No 2 (2025): Jurnal Ilmiah Medicamento (In progress)
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i2.11418

Abstract

In recent years, the therapeutic potential of polyherbal formulations as aphrodisiacs, particularly as natural alternatives to synthetic treatments for sexual health disorders, has garnered significant attention. Polyherbal formulations are believed to enhance efficacy through synergistic effects, making them a preferred option in both traditional and modern therapeutic practices. This review aims to provide a comprehensive analysis of research trends relating to the use of polyherbal formulations for aphrodisiac purposes. A bibliometric analysis was conducted using the Scopus database, extracting relevant articles with the keywords 'Aphrodisiac AND Polyherbal OR Combination.' From an initial pool of 88 articles, 16 were selected for in-depth analysis. VOSviewer software was used to visualize collaboration networks, co-authorship patterns, and keyword trends, highlighting the increasing research interest in polyherbal formulations for sexual health enhancement. The narrative review supplements these findings by exploring study methodologies, sources of herbal ingredients, formulation compositions, and commonly used herbs. Results indicate that while polyherbal aphrodisiac formulations show promising therapeutic potential, research in this field remains fragmented, with limited clinical trials evaluating safety and efficacy. The most frequently studied herbs include Tribulus terrestris, Mucuna pruriens, and Withania somnifera, known for their effects on testosterone levels, vascular function, and libido enhancement. Future studies should focus on clinical validation, standardization, and pharmacokinetic assessments to facilitate their integration into modern medical practice. These findings provide valuable insights for researchers and industries developing polyherbal-based nutraceutical and pharmaceutical products.
Co-Authors Anak Agung Ketut Sri Trisna Dewi Widhiani Anton, Sri Sulistyawati Ariani, Ni Nyoman Ayu Nilam Tresna Dewi Darmo Suputra, I Kadek Dewi Puspita Apsari Dewi, Ni Made Umi Kartika Diaris, Ni Made Dwi Hadi Setya Palupi Emy Suryanti, Putu I Gusti Agung Sri Astuti I Kadek Darmo Suputra, I Kadek Darmo I Ketut Adnyana I Made Dwitayasa I Made Sugata I Nyoman Agus Pradnya Wiguna I Wayan Redi Made G. Juniartha Made Krisna Adi Jaya Mahardika, Ida Bagus Putra Ni Ketut Ni Ketut Sinarsih Ni luh Sri Rahayuni Ni Made Dwi Mara Widyani Nayaka Nugraha, Iwan Saka Nyoman Eva Sri Wahyuni Purnamawati, Dr. Made Sri Putri Puspita Apsari , Dewi Putu Judy Satyawati Sudarmo Setyawan Guna Dharma Sinarsih, Ni Ketut Suryani Suryani Wartana Putra, I Gusti Ngurah Agung Windra Wika, I Made