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All Journal MEDIA MEDIKA INDONESIANA MNJ (Malang Neurology Journal) Majalah Kesehatan FKUB Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Contemporary Nursing Journal (ICON Journal) CRJIM (Clinical and Research Journal in Internal Medicine) MEDICINUS The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia IJRETINA - International Journal of Retina Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD)
Rulli Rosandi
Faculty Of Medicine Brawijaya University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Other

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Journal : MEDICINUS

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Dislipidemia Aterogenik pada Pasien Diabetes Melitus Tipe 2: Patofisiologi dan Pilihan Terapi Rosandi, Rulli
MEDICINUS Vol. 34 No. 1 (2021): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.894 KB) | DOI: 10.56951/medicinus.v34i1.47

Abstract

Atherogenic dyslipidemia is characterized by increase in triglyceride and small dense lipoprotein (sdLDL) level and decrease in high-density lipoprotein (HDL) level. This condition is accompanied by increased TG-rich very-low-density lipoprotein, apolipoprotein B, and oxidized low-density lipoprotein (oxLDL). This lipid profile plays an important role in the pathogenesis of cardiovascular disorders such as coronary heart disease, peripheral artery disease, and stroke. Diabetes mellitus is an independent risk factor for premature atherosclerosis. High- and moderate-intensity statins are recommended therapeutic options in the management of this disorder. Currently, there are also some therapeutic options other than statin to accompany statin therapy. Ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor are mentioned a lot in current lipid management guidelines in addition to nonpharmacologic approach such as diet and physical exercise.
Co-Authors Abda Abda Achmad Rudijanto Andreas Budi Wijaya Arie Srihardyastutie Arsana, Putu Moda Atma Gunawan Aulanni'am, Aulanni'am Aulia Abdul Hamid Dina Dewi SLI Ferdiana , Asihanti Heri Kristianto Irawan, Paulus Lucky Tirma Kusworini Handono Laksmi Sasiarini Megawanto, Nur Handy Muthiah, Mark Nadia Artha Dewi Nasution, Ali Napiah Ni Kadek Indah Sunar A Nyoman Satvika Dharma Yudha Purnama, Avief Destian Puspasari, Eka Fajarina Putri, Mutiara Kristiani Putu Moda Arsana Rahmasari, Herisa Rakhman, Muhammad Ramadani, Devi Rinadhi Reza Bramantya Rinik Eko Kapti, Rinik Eko Safira, Zahra Sasiarini, Laksmi Seskoati Prayitnaningsih Shahdevi Nandar Kurniawan, Shahdevi Nandar Supriono ., Supriono Suryana, Bagus Putu Putra Syifa Mustika Wibowo, Bogi Pratomo Wuragil, Dyah Kinasih Yeni Rahman, Yeni Yudha, Nyoman Satvika Dharma Yuyun Yueniwati