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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. DEVOTE: Jurnal Pengabdian Masyarakat Global TAMPIASIH
Soufa Malita
Institut Teknologi dan Kesehatan Aspirasi
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Education Environmental Science Health Professions Medicine & Pharmacology Public Health Social Sciences Other

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Tanaman Herbal Indonesia yang Memiliki Aktivitas Sebagai Antikanker Soufa Malita; Rahayu Safitri Rahman
JURNAL TAMPIASIH Vol. 2 No. 1 (2023): Desember
Publisher : LPPM, Institut Teknologi dan Kesehatan Aspirasi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar Belakang: International Agency for Research on Cancer (2014) melaporkan bahwa jumlah kejadian kanker di Indonesia terus meningkat setiap tahunya. Union for Internasional Cancer Control (UICC) juga melaporkan bahwa pada tahun 2020 terdapat 19,3 juta kasus kanker. UICC memperkirakan pada tahun 2040 akan meningkat menjadi 30 juta. Sejauh ini, terapi kanker masih menggunakan pembedahan radiasi, dan kemoterapi. Metode tersebut memiliki kekurangan, diantaranya pembedahan konvensional menyebabkan pasien kehilangan seluruh atau sebagian anggota tubuhnya. Terapi radiasi menggunakan sinar laser berkekuatan tinggi, sedangkan kemoterapi menggunakan zat kimia atau obat-obatan yang berbahaya bagi tubuh. Sebagai cara alternatif, dapat digunakan tanaman herbal yang memiliki kemampuan spesifik membunuh sel kanker dan relative lebih aman. Oleh karena itu studi literatur review ini dilakukan untuk memperoleh informasi tentang tanaman herbal Indonesia yang memiliki aktivitas sebagai antikanker. Metode: Metode yang digunakan dalam penelitian ini adalah telaah literatur yang   dilakukan   dengan   menggunakan   data base   Google Scholar.  Beberapa literatur diperoleh menggunakan kata kunci “antikanker, tanaman herbal, kanker, tumor payudara,”literatur yang didapatkan kemudian diolah dan diseleksi berdasarkan tujuan dari artikel ini. Hasil: Hasil telaah literatur ini memperoleh beberapa jurnal yang berkaitan dengan tanaman herbal Indonesia yang memiliki aktivitas sebagai antikanker. Beberapa jurnal juga memaparkan bahwa tanaman herbal Indonesia dapat mencegah pertumbuhan tumor, leukemia, kanker serviks dan lainnya. Kesimpulan: Telaah literatur ini difokuskan pada berbagai jenis tanaman herbal Indonesia yang memiliki aktivitas sebagai antikanker.
PENINGKATAN KAPASITAS KEMAMPUAN MENULIS KARYA TULIS ILMIAH BERSTANDAR JURNAL ILMIAH NASIONAL BEREPUTASI MENGGUNAKAN APLIKASI SITASI ILMIAH MENDELEY Muhammad Junaedi; Khairul Khalqi; Soufa Malita; M Zainul Hafizi
Devote: Jurnal Pengabdian Masyarakat Global Vol. 4 No. 4 (2025): Devote: Jurnal Pengabdian Masyarakat Global, 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/devote.v4i4.5099

Abstract

Writing ability is an essential academic skill in higher education because it serves as a means to communicate ideas, construct logical arguments, and produce credible and accountable scholarly works. The national standards for scientific writing are a set of formal guidelines that regulate the structure, language rules, writing format, academic ethics, as well as citation and referencing procedures to ensure academic quality, scientific integrity, and consistency in every scholarly work produced. Mendeley is one of the reference management applications used to organize bibliographies, store scientific articles, generate automatic citations, and assist researchers in formatting references according to the required style. The enhancement of writing skills through the use of Mendeley is based on the needs of students in completing their final assignments at the university. This activity is implemented through four stages: planning, implementation, evaluation, and program sustainability. During the implementation stage, the program includes workshops on utilizing the Mendeley application, training in searching for scientific references, and hands-on practice using the application. The success of the program is evaluated by assessing students’ responses to the use of Mendeley through questionnaires and analyzing their feedback regarding the program activities. The results indicate that students have a positive perception of using Mendeley, with an average score of 90.8%, while their response to the implementation of the program reaches 85.7%.
Toxicity and α-Glucosidase Inhibitory Activity of Chromolaena odorata L. for Antidiabetic Herbal Tea Soufa Malita; Muhammad Junaedi
Saintika Medika : Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol. 22 No. 1 (2026): June 2026
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol22.SMUMM1.44123

Abstract

Background: Coppasanda (Chromolaena odorata) is a weed plant containing secondary metabolites with potential antidiabetic activity by lowering blood glucose levels. This plant has been developed into a tea bag formulation. Previous studies reported that Coppasanda tea significantly reduced blood glucose levels in alloxan-induced rats; however, higher concentrations caused unstable glucose levels. Therefore, toxicity testing and α-glucosidase inhibitory assays are required to evaluate its safety and enzyme-inhibiting potential. Objectives: This study aimed to determine the toxicity profile and α-glucosidase inhibitory activity of Coppasanda tea bags. Methods: Acute toxicity testing was conducted in vivo using 30 mice divided into five groups: control (0.5% CMC-Na), P1 (50 mg/kg BW), P2 (300 mg/kg BW), P3 (1000 mg/kg BW), and P4 (2000 mg/kg BW). The α-glucosidase inhibition assay was performed in vitro using p-nitrophenyl-α-D-glucopyranoside (pNPG) as the substrate and α-glucosidase enzyme. Absorbance was measured using a spectrophotometer at 405 nm. Results: The toxicity test showed no toxic symptoms of Coppasanda tea bags, indicated by the absence of significant changes (P > 0.05) in body weight, mortality, clinical signs, and organ indices of the experimental animals. In vitro results demonstrated strong α-glucosidase inhibitory activity, with a maximum inhibition of 98% and an IC₅₀ value of 29 µg/mL. Conclusion: Coppasanda tea bags are non-toxic and exhibit strong α-glucosidase inhibitory activity, indicating potential as a safe antidiabetic herbal beverage.
Co-Authors Khairul Khalqi M Zainul Hafizi Muhammad Junaedi Rahayu Safitri Rahman