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All Journal Biosfer: Jurnal Tadris Biologi CHEMPUBLISH JOURNAL RACIC : Rab Construction Research JURNAL PengaMAS Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat Journal Of Research and Education Chemistry (JREC) Jurnal Pengabdian West Science Jurnal Pengabdian Masyarakat Bangsa JURNAL KARYA ILMIAH MULTIDISIPLIN
Yoan De Nanda Herru
Universitas Lancang Kuning
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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KUAT GESER TANAH LEMPUNG DENGAN VARIASI PENAMBAHAN LIMBAH BETON fitridawati soehardi; Marta Dinata; Yoan De Nanda Herru; Junaidi
Racic : Rab Construction Research Vol. 10 No. 1 (2025): JUNI 2025
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/racic.v10i1.5086

Abstract

Clay soil tends to expand when wet and contract when dry, which can cause cracks in the soil or damage to the building structure above it if not handled properly. One effort that can be carried out is chemical stabilization using both conventional stabilization materials and the use of alternative stabilization materials, both organic and inorganic. The aim of this research is to increase the shear strength of the soil by adding varying percentages of 5%, 10%, 15% and 20% of concrete waste. The method used is an experimental method in the laboratory using SNI 3420:2016 testing for shear strength. The research results show that there is an increase in cohesion values ​​and shear angles along with the addition of concrete waste. The highest increase was found in the percentage of 20% addition of concrete waste to the original soil, namely the cohesion value was 0.400 kg/cm2 and the shear angle value was 24.567 0.
In silico and In vitro Study of The Anticancer Potential of Essential Oil from Sembung (Blumea balsamifera) Leaves against HeLa Cervical Cancer Cells Ulia, Rahmi Vika; Raharto, Toto; Suryati; Santoni, Adlis; Herru, Yoan De Nanda
Chempublish Journal Vol. 10 No. 1 (2026): Chempublish Journal (January - June)
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v10i1.49160

Abstract

Blumea balsamifera (L.) DC. (sembung) is a medicinal plant widely recognized for its diverse pharmacological properties, including cytotoxic and anticancer activities. However, the anticancer potential of its leaf essential oil against cervical cancer remains poorly explored. This study aimed to evaluate the anticancer activity of B. balsamifera leaf essential oil against HeLa cervical cancer cells using integrated in silico and in vitro approaches. Molecular docking analysis against the anti-apoptotic Bcl-2 protein revealed favorable binding affinities for several major constituents, including camphor (-5.745 kcal/mol), caryophyllene (-7.077 kcal/mol), 7-epi-silphiperfol-5-ene (-7.311 kcal/mol), and γ-eudesmol (-7.083 kcal/mol), indicating potential interactions with apoptosis-related targets. Furthermore, cytotoxic activity assessed by the MTT assay demonstrated an IC₅₀ value of 32.90 µg/mL against HeLa cells, indicating moderate cytotoxic potency. These findings suggest that B. balsamifera leaf essential oil possesses promising anti-cervical cancer activity and may serve as a potential natural source for the development of apoptosis-targeting anticancer agents.
Co-Authors Adlis Santoni Afidah, Mar’atul Alfin Surya Anggrena D. Ritonga Azwin, . Diova Ritonga , Anggrena Diova Ritonga, Anggrena ENNIE CHAHYADI, ENNIE Fadilaturahmah Fadilaturahmah Fitridawati Soehardi, Fitridawati Hazra Yuvendius Hesti Marliza Ikhsan, Fikratul Joni, Rahma Junaidi Malas Sari, Yuni Marta Dinata Raharto, Toto Rahmi Vika Ulia Ritonga, Anggrena Diova Rokim, Muhamad Sri Rahayu Prastyaningsih Sri Wahyuni Suryati Widya Widya, Widya Yelmiza