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MODELING OF MATERNAL MORTALITY (MMR) IN EAST JAVA 2017-2019 USING PANEL REGRESSION APPROACH Febriyanto, Eka Cahya; Indawati, Rachmah; Mahmudah, Mahmudah; Ama, Fuad; Ashari, Faisal Yusuf
Jurnal Biometrika dan Kependudukan (Journal of Biometrics and Population) Vol. 12 No. 2 (2023): JURNAL BIOMETRIKA DAN KEPENDUDUKAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbk.v12i2.2023.177-185

Maternal Mortality Rate (MMR), is a country's welfare indicator especially about the women's health. It is included in the development index and the quality of life index. The determinants of maternal mortality are elements that collectively cause maternal mortality. This quantitative research used secondary data on MMR and its influencing factors in East Java Province during the 2017-2019 period and the analysis of the panel data used regression. The trend of Maternal mortality in East Java Province has decreased from year to year; in 2019, it was 89.81 per 100,000 live births. The variable pregnant women using blood-added pills (X1) with a probability value of 0.020 (p<0.05) is found to significantly affected the maternal mortality in the panel regression analysis utilizing the Random Effect Model. The Random Effect Model, which this study found to be the best, contains the model equation Yit = 225.7721 - 1.919457 X1it and the administration of blood-added pills is the variable that significantly affects maternal mortality. The results of this study indicate the need for educational efforts, especially regarding to the benefits of blood-added pills for pregnant women and to correct the misunderstanding about the benefits of blood-added pills in the community, so that the coverage of blood supplement consumption in pregnant women can be increased. Together with the primary health care system and obstetricians, an integrative approach and counseling among pregnant women and their partners will increase awareness of maternity health and birth management.

The Inframerah untuk Kesembuhan Investigasi Terapi Terhadap Penyembuhan Luka Insisi dalam Konteks Ilmu Kesehatan Rianti, Emilia Devi Dwi; Simamora, Dorta; Ama, Fuad
BIOSAPPHIRE: Jurnal Biologi dan Diversitas Vol. 3 No. 1 (2024): BIOSAPPHIRE
Publisher : Program Studi Biologi, Fakultas Sains dan Teknologi, UNIPAR JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31537/biosapphire.v3i1.1742

Currently, alternative therapies are widely used with the aim of reducing pain, swelling and increasing blood circulation. Infrared rays are used in research as a therapy for healing incisional wounds because infrared can penetrate cells or tissue more deeply. Infrared rays in research as a therapy for healing incisional wounds. The experimental animal samples were 24 male Wistar rats treated with K (-) without infrared therapy, P1 was given infrared exposure at a distance of 24 cm and for 20 minutes. P2 was given infrared exposure at a distance of 16 cm and a time of 20 minutes and P3 was given infrared exposure at a distance of 7 cm and a time of 20 minutes. The results showed that the 12th day change in wound healing occurred in the control group = 0.1 cm; P1= 0.2 cm; P2 = 0.4 cm and P3 = 0.5 cm. The conclusion of the research was that effective infrared therapy was shown in treatment group 1 (P1) with an exposure distance of ± 24 cm, because infrared radiation entered the subcutaneous tissue without excessive stimulation or heating

Analisis Kejadian Adverse Drug Reaction Obat Anti-Tuberkulosis dengan Faktor Risiko pada Penderita Tuberkulosis Multi-Drug Resistant : Systematic Review Andili, Agshal Almachzumi; Setiawan, Budhi; Ama, Fuad; Raharjo, Budiono
Calvaria Medical Journal Vol 2 No 1 (2024): Edisi Juni 2024 (available online Juli 2024)
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/cmj.v2i1.35

Introduction: Tuberculosis patients must adhere to a six-month uninterrupted course of medication. The DOTS method is crucial in preventing resistance to anti-TB drugs, which can lead to stronger MDR-TB strains resistant to rifampicin and isoniazid. ADRs from these drugs include gastrointestinal disturbances, hepatotoxicity, dermatological and serious neurological disorders, prompting patients to discontinue treatment. Non-adherence can hinder tuberculosis recovery as patients tend to stop treatment. Patient compliance is pivotal in their decision to continue treatment. Therefore, further research is needed to explore the relationship between ADRs to anti-TB drugs and risk factors in active MDR-TB patients. Method: This qualitative study conducted a literature review using databases from 2014 to 2023 and keywords relevant to the study's title. Fifteen relevant journals were identified, comprising 11 international and 4 national journals. Results: The literature review found that the most influential factors in adverse drug reactions to OAT in outpatient MDR-TB patients were treatment history and medication adherence. Regarding individual factors such as age and gender, most journals indicated they are not significant risk factors for MDR-TB. Conclusion: Based on the literature review, it can be concluded that the most dominant factors affecting adverse drug reactions to OAT in outpatient MDR-TB patients are treatment history and medication adherence. As for individual factors like age and gender, nearly all journals indicate they are not significant risk factors for MDR-TB.

EFEKTIVITAS TERAPI INFRAMERAH TERHADAP PENYEMBUHAN LUKA INSISI TIKUS PUTIH JANTAN Rianti, Emillia Devi Dwi; Purbowati, Rini; Ama, fuad
Prosiding Seminar Nasional COSMIC Kedokteran Vol 3 (2025): Edisi 2025
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat Universitas Wijaya Kusuma Surabaya

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Luka insisi adalah salah satu luka terbuka yang disebabkan oleh pisau bedah, maka diperlukan pengobatan yang pada umumnya menggunakan obat konvensional salah satunya antibiotik secara topikal. Obat-obatan medis dalam penggunaannya dalam jangka panjang akan berefek samping bagi tubuh maka perlunya pemanfaatan pengobatan secara artenatif seperti penggunaan terapi inframerah. Metode, eksperimen dengan metode rancangan acak lengkap dan populasi penelitian tikus putih wistar jantan sebanyak 24 ekor dengan berat badan 250-300 gram, berusia 2-3 bulan. Luka insisi sepanjang 2 cm dan kedalaman 0,1 mm dan dibagi kedalam beberapa kelompok pemberian terapi, dengan kelompok kontrol dan perlakuan. analisa berdasarkan efektivitas penyembuhan luka insisi dengan menggunakan terapi inframerah dan Skor Nagaoka memiliki tiga kriteria dalam menilai penyembuhan luka. Jika waktu penyembuhan luka 14 hari didapatkan skor nagaoka 1 (lambat). Hasil, kelompok kontrol penyembuhan pada hari ke-11 dengan panjang luka 0,5 cm. Kelompok perlakuan P1 (24 cm) pada hari ke-8 dengan panjang luka 0,4 cm, P2 (16 cm) pada hari ke-7 dengan panjang luka 0,5 dan P3 (7 cm) pada hari ke-9 dengan panjang luka 0,5 cm. Skor penilaian Nagaoka, penyembuhan luka P1 : skor 2, P2: skor 2 dan P3 :skor 2.Kesimpulan, pemberian terapi inframerah sangat efektif didalam penyembuhan luka insisi tikus putih jantan dan hasil skor menunjukkan penyembuhan sedang. Penyembuhan dengan terapi inframerah tidak terjadi granulasi yang dapat menimbulkan infeksi.

The Overview of the Effectiveness of Infrared on the Healing Rate of Incision and Burn Wounds in Male White Rats Ama, Fuad; Purbowati, Rini; Rianti, Emillia Devi Dwi
Electronic Journal of Education, Social Economics and Technology Vol 5, No 2 (2024)
Publisher : SAINTIS Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33122/ejeset.v5i2.235

Infrared rays have low energy and their use does not cause toxic effects on the environment, so that infrared rays can balance and activate cells in the body, thin the blood, break down water molecules, and inhibit bacteria or fungi. Inhibition of bacterial or fungal growth in skin wounds that are often experienced and cause damage to epithelial tissue. The purpose of the study provides an overview of the effectiveness of infrared on the healing rate of incision wounds and burns in Wistar rats. The method with an experiment with a completely randomized design method, the sample used was 48 male white rats with 24 with incision wounds and 24 with burns. The results of the incision wound on the 12th day showed that there was a reduction in the length of the wound at P1 (0.1 cm), P2 (0.1 cm) and P3 (0.2 cm) so that with a wound length of 0.1 means healing has occurred. Burns on the 12th day there was a decrease in the diameter of the burn wound both at P1 = P2 = P3 = 0.3 cm. Conclusion The use of infrared therapy in the healing process of incision wounds and burns on days 9-12. Infrared wavelength 940 nm as near infrared produces heat, so the healing process is less than 14 days.

The Inframerah untuk Kesembuhan Investigasi Terapi Terhadap Penyembuhan Luka Insisi dalam Konteks Ilmu Kesehatan Rianti, Emilia Devi Dwi; Simamora, Dorta; Ama, Fuad
BIOSAPPHIRE: Jurnal Biologi dan Diversitas Vol. 3 No. 1 (2024): BIOSAPPHIRE
Publisher : Program Studi Biologi, Fakultas Sains dan Teknologi, UNIPAR JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31537/biosapphire.v3i1.1742

Currently, alternative therapies are widely used with the aim of reducing pain, swelling and increasing blood circulation. Infrared rays are used in research as a therapy for healing incisional wounds because infrared can penetrate cells or tissue more deeply. Infrared rays in research as a therapy for healing incisional wounds. The experimental animal samples were 24 male Wistar rats treated with K (-) without infrared therapy, P1 was given infrared exposure at a distance of 24 cm and for 20 minutes. P2 was given infrared exposure at a distance of 16 cm and a time of 20 minutes and P3 was given infrared exposure at a distance of 7 cm and a time of 20 minutes. The results showed that the 12th day change in wound healing occurred in the control group = 0.1 cm; P1= 0.2 cm; P2 = 0.4 cm and P3 = 0.5 cm. The conclusion of the research was that effective infrared therapy was shown in treatment group 1 (P1) with an exposure distance of ± 24 cm, because infrared radiation entered the subcutaneous tissue without excessive stimulation or heating

Survival Pasien Kanker Kolorektal di RSUD Nganjuk dan Ekspresi Gen APC, KRAS dan SMAD4 Pada Tumornya Hernanda, Pratika Yuhyi; Pramugyono, Pramugyono; Wulandari, Ida Septika; Agusaputra, Harman; Sugeng, Maria Wijayanti; Ama, Fuad; Shalsabillah, Nadia Fitri
Majalah Kedokteran Indonesia Vol 75 No 5 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.5-2025-1830

Introduction: The survival of colorectal cancer patients is significantly influenced by comorbid factors, including age, smoking, obesity, comorbidities, and genetics. The purpose of this study was to analyze factors affecting colorectal cancer survival in Nganjuk Regional General Hospital and to examine the expression of the APC, KRAS, and SMAD4 genes in tumor tissue.Methods: We analyzed the comorbid factors in 51 colorectal cancer patients and then analyzed their relationship to colorectal cancer survival. Immunohistochemistry (IHC) staining was performed to examine the expression of the KRAS, APC, and SMAD4 genes in colorectal cancer tissue. Data were analyzed using bivariate analysis between variables using the Chi-square test, and survival analysis was performed using Kaplan-Meier statistical analysis.Results: The data shows that colorectal cancer patients with comorbidities tend to have a lower survival rate than those without comorbidities (P-value 0.054), and patients with metastases also have a lower survival rate (P-value 0.748). APC and SMAD4 gene expression in stromal tissue IHC was more dominant than KRAS gene expression in the stroma. Increased gene expression in the stroma indicates its role in tumor invasion and metastasis.Conclusion: Comorbidities and the presence of metastases negatively impact the survival rate of colorectal cancer patients. APC and SMAD4 gene expression in the stromal tissue was more dominant than KRAS gene expression in the stroma, suggesting a role for these genes in tumor invasion and metastasis.

SKRINING KANKER PARU DI POSYANDU LANSIA NIRMALA WAGE SIDOARJO Hernanda, Pratika Yuhyi; Arimbi, Muzaijadah Retno; Sugeng, Maria Widijanti; Agusaputra, Harman; Ama, Fuad; Widayati, Lilis
Prosiding Seminar Nasional COSMIC Kedokteran Vol 4 (2026): Edisi 2026
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat Universitas Wijaya Kusuma Surabaya

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Latar belakang: Skrining kanker paru adalah pemeriksaan untuk mendeteksi dini kanker paru-paru. Dalam hal ini dilakukan pemeriksaan foto Rontgen dada bagi masyarakat yang beresiko tinggi dan atau bergejala. Skrining ini penting dilakukan karena kanker paru-paru seringkali tidak menimbulkan gejala hingga stadium lanjut. Skrining kanker paru-paru direkomendasikan untuk orang-orang yang berisiko tinggi, seperti: perokok atau mantan perokok, memiliki riwayat keluarga dengan kanker paru dan usia lebih dari 40 tahun. Metode: Pengabdian masyarakat dengan edukasi kanker paru dan Pemeriksaan foto thoraks. Hasil: Setelah dilakukan edukasi tentang kanker Paru di Balai RW 12 Posyandu Lansia Nirmala Wage, 15 pasien yang sesuai kriteria dilakukan pemeriksaan Foto Thoraks dimana masyarakat ini beresiko tinggi atau yang memiliki gejala kanker paru minimal batuk yang tidak kunjung sembuh dan atau penurunan berat badan yang tidak jelas penyebabnya. Sebanyak 3 dari 15 pasien (20%) memiliki gangguan paru pada hasil foto thoraksnya, sehingga pasien bisa dirujuk ke fasilitas kesehatan untuk mendapat penanganan lebih lanjut. Pengetahuan masyarakat akan kanker paru juga meningkat setelah dilakukannya Edukasi di Seminar kanker paru yang kami selenggarakan sehingga harapannya kejadian kanker paru dapat ditekan di masyarakat. Kesimpulan: Deteksi dini kanker paru dapat dilakukan dengan skrining melalui anamnesa, pemeriksaan fisik dan pemeriksaan foto thoraks. Edukasi kanker paru dapat meningkatkan kesadaran dini akan kesehatan paru di masyarakat.

KARAKTERISTIK KANKER PARU DI PRAKTEK SWASTA SURABAYA TAHUN 2017-2020 Agusaputra, Harman; Parengkuan, Irene Lingkan; Hernanda, Pratika Yuhyi; Sugeng, Maria W; Ama, Fuad
Prosiding Seminar Nasional COSMIC Kedokteran Vol 4 (2026): Edisi 2026
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat Universitas Wijaya Kusuma Surabaya

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Latar Belakang: Kanker paru merupakan kanker yang cukup mengkuatirkan dan menjadi penyebab kematian terbanyak di dunia, Insiden secara keseluruah no 2 setelah kanker payudara. Diantara laki-laki umumnya terjadi peningkatan lebih banyak 2x lipat dibanding perempuan. Indonesia diperkirakan mempunyai resiko tinggi kanker paru, bersamaan dengan china dan negara eropa. Tujuan: penelitian ini ingin memperkuat epidemologi data epidemologi. Metode: Penelitian dilakukan secara cross sectional, diambil data sekunder dari praktek besama di Surabaya. Kriteria inklusi kasus pasien kanker paru didiagnosa dengan mengunakan FNAB CT guiding dalam kurun waktu 2017-2020 dengan total sampel 168 suspek kasus kanker paru. Hasil: Dari 108 kasus kanker paru ditemukan di Surabaya laki-laki lebih banyak 67,5% dengan ratio laki-laki : perempuan 2:1 . usia rerata terdiagnosis 56,4 tahun, usia termuda umur 27 tahun dan tertua umur 84 tahun. Range 61-70 tahun. Lokasi terbanyak paru sebelah kanan 56,4% dan Morfologi tumor terbanyak adalah Adenocarcinoma sebanyak 73 %. Kesimpulan: Karsinoma paru banyak dijumpai pada laki-laki dan kecenderungan pada perempuan akan terjadi peningkatan, dan dapat juga terjadi pergeseran rereta usia 61-70 tahun, paru sebelah kanan tetap menjadi kasus lokasi terbanyak dan tipe adenocarcinoma merupakan trend terbanyak.

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