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All Journal HAYATI Journal of Biosciences Science and Technology Indonesia Aqwal: Journal of Quran and Hadies Studies
Aulanni’am, Aulanni’am
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Earth & Planetary Sciences Environmental Science Materials Science & Nanotechnology Physics Social Sciences

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Kaidah Amr-Nahy, Qarinah, dan Penafsiran Quraish Shihab tentang Jilbab (Sebuah Kajian Terhadap Kaidah Tafsir) Aulanni’am, Aulanni’am; Andi Tri Saputra
Aqwal: Journal of Qur'an and Hadis Studies Vol 2 No 2 (2021)
Publisher : Universitas Islam Negeri K.H. Abdurrahman Wahid Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28918/aqwal.v2i2.6020

Abstract

This article tries to discuss and explain how the rules of Amr and Nahy and the concept of Qarinah work in understanding the Qur'an, specifically to obtain a law. This is motivated by the basic rules of Amr and Nahy itself, where each principle basically shows an obligation and prohibition on a case, but the law can change with the  discovery of Qarinah. In this article Qarinah is explained as the proposition, where the arguments can be of various kinds, can be found in the text of the verse itself or other texts, or with the concept of ushul fiqh such as Istihsan, Istislah and Istishab. In this article a particular case is raised to see how Amr-Nahy and the Qarinah concept work, the case is about the law wearing the hijab in the interpretation of the Quraish Shihab, where in its interpretation it does not require the use of the hijab. This article shows how this interpretation is based on a particular Qarinah, in this case closely related to the rules of Istihsan and Urf.
Development of Fermented Coconut Water and Red Ginger using Next Generation Probiotics as a Potential Biological Activity Agent Nabila, Sofi; Srihardyastutie, Arie; Aulanni’am, Aulanni’am; Ardiyati, Tri
HAYATI Journal of Biosciences Vol. 32 No. 5 (2025): September 2025
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.32.5.1337-1351

Abstract

Degenerative diseases have increased in prevalence worldwide, predominantly in Indonesia. Some studies found that probiotics have an impact on organic substances that address inflammation and gut microbiota imbalance. This study aims to develop a functional beverage based on coconut water and red ginger fermentation using Next Generation Probiotics (NGP) and characterize the product using metagenomic and metabolomic technologies. This experimental study involved the fermentation of coconut water and red ginger using a probiotic starter identified by 16S rRNA sequencing for 120 hours at room temperature. The analysis included microbial characterization using List the probiotics metagenomic sequencing, metabolite profiling by LC-HRMS, particle size by PSA, and in vitro antibacterial and anti-inflammatory activity testing. Metagenomic analysis identified the dominance of the family Acetobacteraceae (45%) and genus Acetobacter 942%. Fermentation reduced the tannin content by 28.5% and increased the number of metabolite compounds from 37 to 54. The fermentation results also showed antibacterial activity against E. coli CNN 0091 (inhibition zone 7.835 mm), and anti-inflammatory activity reached 1,000%. The combination of coconut water, red ginger, and NGP produced a complex metabolite profile with high therapeutic potential. The findings show significant potential for the prevention of degenerative diseases.
Potential Analysis of Snakehead Fish Albumin Extract (Channa striata) as Immunostimulant and Anti-Inflammatory in Indomethacin-Induced Inflammatory Bowel Disease (IBD) Rats Panjaitan, Tina Fransiskha Carolyn; Fiddaroini, Saidun; Suprayitno, Eddy; Aulanni’am, Aulanni’am; Hardoko, Hardoko
Science and Technology Indonesia Vol. 10 No. 3 (2025): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.3.725-740

Abstract

Inflammatory Bowel Disease (IBD) is a chronic gastrointestinal disorder driven by oxidative stress and immune dysregulation, often exacerbated by prolonged non-steroidal anti-inflammatory drug (NSAID) use. Conventional therapies provide symptomatic relief but are limited by severe adverse effects, necessitating safer alternatives. Channa striata (snakehead fish) is a rich source of albumin, essential amino acids, and bioactive compounds with potential immunomodulatory and anti-inflammatory effects. This study investigates the therapeutic efficacy of purified Channa striata albumin extract in an indomethacin-induced IBD rat model. Albumin was isolated via ammonium sulfate precipitation and characterized by SDS-PAGE, antioxidant activity (DPPH assay), and amino acid profiling. Rats were treated with Channa striata albumin (100-300 mg/kg BW) for 14 days post-indomethacin induction. Compared to controls and diclofenac-treated groups, the extract significantly reduced malondialdehyde (MDA) levels (up to 90.69%), improved jejunal histoarchitecture, and enhanced occludin expression. Immunohistochemistry showed a marked reduction in CD4+T cell infiltration, indicating immunomodulatory activity. These findings establish Channa striata albumin as a potent natural antioxidant and immunomodulator, offering a safer alternative to NSAIDs for IBD management.
Co-Authors Andi Tri Saputra Arie Srihardyastutie Eddy Suprayitno Fiddaroini, Saidun Hardoko Hardoko Nabila, Sofi Tina Fransiskha Carolyn Panjaitan, Tina Fransiskha Carolyn Tri Ardiyati