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All Journal Pharmascience JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Jurnal Kesehatan Tambusai Jurnal Buana Farma Jurnal Kesehatan Kusuma Husada JPEMAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmu Kesehatan
Amrullah, Adhi Wardhana
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Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Other

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Journal : Jurnal Buana Farma

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KAJIAN RASIONALITAS PENGGUNAAN ANTIBIOTIK PADA ANAK DENGAN INFEKSI SALURAN KEMIH DI RSUD Dr. MOEWARDI SURAKARTA Agustiningrum, Frisda Ayu; Amrullah, Adhi Wardhana; Rahardjoputro, Rolando
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1118

Abstract

Urinary tract infection (UTI) is the second highest infectious disease among children in Indonesia. Management of UTI requires antibiotic therapy, but the irrational use of antibiotics makes this disease one of the contributors to the high rate of antibiotic resistance. Therefore, there is a need for a study to measure the rationality of antibiotic use in children with UTI. This study is a descriptive observational study with a cross sectional design. Data were collected retrospectively using a purposive sampling technique based on medical record data of pediatric patients at Dr. Moewardi Surakarta Hospital in 2021-2023. The results showed that out of 100 medical records of pediatric patients with UTI, 68.00% were women and 32.00% were men. Based on age, the highest incidence of UTI occurred in the age range of 10-18 years as much as 52.00%. The most common antibiotic use was ampicillin 68.00%. The results of the rationality study showed 69.00% in category 0 (rational use of antibiotics). Irrationality occurred in category IIA (antibiotic use is not the right dose) 17.00%, IIIA (antibiotic use with too long duration) 1.00%, IIIB (antibiotic use with too short duration) 4.00%, IIA & IIIB (antibiotic use is not the right dose & duration is too short) 2.00%, IVA (there are other more effective antibiotic options) 4.00%, IIIB & IVA (antibiotic use is too short duration & there are other more effective antibiotic options) 3.00%. It can be concluded that the rational use of antibiotics needs to be improved.
A KAJIAN POTENSI INTERAKSI OBAT PADA PASIEN GERIATRI DENGAN GAGAL JANTUNG DI RSUD Dr. MOEWARDI SURAKARTA TAHUN 2023 Safira, Della Anggun; Amrullah, Adhi Wardhana; Rahardjoputro, Rolando
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1129

Abstract

Geriatric patients with heart failure generally receive more than 1 type of drug therapy, called polypharmacy, which typically involves at least four types of treatment: ACEI (Angiotensin Converting Enzyme Inhibitors), diuretics, beta blockers, and digoxin. This causes an increase in the occurrence of drug interactions. This study aims to determine the potential drug interactions that occur in geriatric patients with heart failure who undergo hospitalization at Dr. Moewardi Surakarta Hospital from January to December 2023. This study is a descriptive observational study with a cross-sectional design, and the data were collected retrospectively using a purposive sampling technique based on the medical records of geriatric patients at Dr. Moewardi Surakarta Hospital in 2023. The inclusion criteria were inpatients aged ≥55 years who were diagnosed with heart failure. The exclusion criteria were patients with incomplete or illegible medical record data or who died during treatment. Drug interaction research was conducted based on Drugs.com and Medscape. The results showed that out of the 100 patients, 98 experienced drug interactions. The incidence of drug interactions was 252 minor cases (21.65%), 818 moderate cases (69.50%), and 106 major cases (9.00%). The mechanism of drug interaction was pharmacodynamic in 919 cases (65.50%), pharmacokinetic in 213 cases (30.40%), and unknown in 44 cases (4.10%).
Co-Authors Agustiningrum, Frisda Ayu Ardya, Hanugrah Budiman, Amin Aji Ernawati Ernawati Ernawati Firman Prastiwi Hidayati, Evi Nurul Hutari Puji Astuti Indriastuti, Isnaini Joko Santoso Maya Fatikasari, Anggita Mellia Silvy Irdianty, Mellia Silvy Moerharyati, Atiek Nikma Alfi Rosida Prawistya Sari, Agnes Prianggi, Herawati Purwaningsih, Avianti Eka Dewi Aditya Raditiya, Mefta Rahardjoputro, Rolando Rahmad, Muhamad Nur Rohana, Qulfattu Rolando Rahardjoputro Rufaida Nur Fitriana Safira, Della Anggun Saraswati, Hanugrah Ardya Crisdian Sardjiman Sari, Agnes Prawistya Sari, Delviana Puspita Sholihah, Inayatush Vierdiana, Dyah Widyastuti , Eersta Zusvita Widyastuti, Eersta Zusvita