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Significant Association of Adam 33 Polymorphism with COPD in Javanese Population of Indonesia Retno Ariza Soeprihatini Soemarwoto; Jamsari; Yanwirasti; Andika Chandra Putra; Syazili Mustofa; Wawan Abdullah Setiawan; Ifan Aulia Candra
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17045

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) is one of World health cases that is commonlyknown, which is triggered by the combination of environmental factors especially cigarette smoking andgenetic factors. The association between A disintegrin and metalloprotease 33 (ADAM33) polymorphismsand COPD has been investigated and reported by other researchers. Objective: The main aim of this study isto identify the association between single nucleotide polymorphisms (SNPs) in ADAM 33 gene with COPDin the Javanese population in Lampung, Indonesia. Methods: A randomized cross-sectional study was usedin this research. PCR-Sequencing method was involved to analyze the polymorphic for three SNPs (T1, T2,and Q-1) of the ADAM33 gene. Statistical analysis data was performed in descriptive and comparative aswell as it was measured by parametric/non-parametric tests. Results: The results showed that the T2 GG,and T1AG genotypes in COPD group were significantly more frequent rather than in control group (p <0.05). In case of allele, it was found that the T1G and T2G was higher in COPD group rather than in thecontrol group (p = 0.440 and 0.131, respectively). Conclusion: The results clearly conclude that there wassignificant association between T1 and T2 polymorphisms of ADAM33 gene and COPD in the Javanesepopulation of Lampung, Indonesia.
The Effect of Tofu Liquid Waste and Organic Mulch on the Growth of Cocoa (Theobroma Cacao L.) Nursery Plants in a Polybag Ifan Aulia Candra; Eri Samah
Journal of Applied Agricultural Science and Technology Vol. 6 No. 2 (2022): Journal of Applied Agricultural Science and Technology
Publisher : Green Engineering Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.718 KB) | DOI: 10.55043/jaast.v6i2.56

Abstract

This study aims to examine the influence of the concentration level of organic tofu liquid waste and rice straw mulch on the growth of cacao (Theobroma cacao L) seedlings. It was carried out using three variables, namely the concentration of tofu liquid waste and four treatment levels. These include treatments without tofu liquid waste 0 ml/kg/plant (T0), and with 60 ml/kg/plant (T1), 80 ml/kg/plant (T2), and 100 ml/kg/plant (T3), respectively. Furthermore, rice straw organic mulch factor with three levels, namely 15 gr/plant (15 tons/ha) (M1), 20 gr/plant (20 tons/ha) (M2), and 25 gr/plant (25 tons/ha) (M3) was also used. The results indicated that the concentration of liquid organic fertilizer derived from tofu liquid waste significantly affected plant height at the age of 3 months. The tallest plant measured 64.78 cm in height, with 21.33 leaves, stem diameter of 0.72, and leaf area of 17.58 cm2. Organic rice straw mulch did not have a significant effect on all plant factors. This showed that the application of liquid organic fertilizer tofu waste influences plant height, leaf number, and stem diameter, and there is no effect on the leaf surface, while rice straw mulch did not alter all plant variables.
Response of Growth and Production of Shallot (Allium ascalonicum L.) to Liquid Fertilizer and Cattle Manure Ifan Aulia Candra; Lisdayani Lisdayani; Eri Samah
Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Vol 12, No 2 (2023): June 2023
Publisher : The University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtep-l.v12i2.268-276

Abstract

The purpose of this research is to improve the physical properties and fertility of soil to improve production of shallot. The research method used is a randomized block factorial design with 3 replication. The first factor was application of liquid fertilizer (N) consisting of 3 levels (N0: 0 cm3/L  water; N1: 1.5 cm3/L  water; N2: 3 cm3/L water). Second factor was cattle manure (A) consisting of 4 levels, namely: A0: 0 g; A1: 40 g cattle manure; A2: 80 g cattle manure; and A3: 120 g cattle manure. The results shown treatment with liquid fertilizer has a significant effect on plant height at weeks after planting (WAP). The study showed that treatment with liquid fertilizer has a significant effect on plant height, tuber weight per clump, and tuber weight per plot, but didn’t not have a significant effect on number of leaves and number of samplings of the shallot plants. Treatment with cattle manure has a significant effect on plant height, tuber weight per clump, tuber weight per plot, and tuber diameter, but does not have a significant effect on number of leaves and number of saplings of the shallot plants. It can be concluded that the higher the application of liquid fertilizer, up to 3 cm3/L , the higher the growth and production of shallot plants, and the higher the application of cattle manure, up to 120 g/plot the higher the growth and production of shallot plants. Keywords:  Plant height, Shallot, Soil Fertility, Tuber weight, Tuber size.
Resistance Analysis of Padi Gogo Merah (Oryza Nivara L) Against Blast Disease Zulheri Noer; Deni Mudsan; Rizal Aziz; Ifan Aulia Candra
Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Vol 13, No 1 (2024): March 2024
Publisher : The University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtep-l.v13i1.37-48

Abstract

Rice Blast has been known as the main disease on paddy which has high severity leading to economic loss. Exploring rice resistance can be an effective way to improve productivity and prosperity toward this staple crop. This study aims to determine several local varieties which have potential for productions and resistances. This study used factorial randomized block design (RBD) consisting of 2 factors including plant spacing (25 x 25 cm; 25 x 30 cm; 25 x 40 cm); Upland rice variety MSP 17, Sigambiri Merah, Hamparan Perak and Kambiri Lumat. The results of the study reveal that variety has a significant effect on disease intensity especially Sigambiri Merah but not on Kembiri Lumat. However, there is no significant effect of spacing on blast intensity except in grain weight. Conclusion of this research was the varieties (V) selection of red upland rice is the best strategy to improve rice resistance toward blast disease. Keywords:  Disease density, Paddy, Staple Crop. 
Pathogenicity Efficacy of Entomopathogen Fungus Beauveria bassiana Against In Vitro Rice Stem Borer (Scirpophaga innotata) Syahbudin Hasibuan; Zulfahmi Simbolon; Ifan Aulia Candra
Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Vol 13, No 2 (2024): June 2024
Publisher : The University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtep-l.v13i2.441-448

Abstract

White rice stem borer (Scirpophaga innotata) is one of the dangerous pests for rice (Oryzae sativa) because it attacks rice stems that can cause 50% loss of total production. The purpose of this study was to determine the pathogenicity of Entomopathogen Fungus Beauveria bassiana at different conidia dilutions (J), namely J1 (105), J2 (106), J3 (107), J4 (108), and J5 (109). The mortality of S. innotata larvae was tested with the density of B. bassiana of 2.08 × 106 conidia/ml. The effect of B. bassiana on the success transformation of S. innotata larvae to pupae for 14 observation day was also observed at the same B. bassiana density. This research resulted in the optimal pathogenicity of B. bassiana at dilution of 107 (treatment J3) which caused 100% death and 100% successful pupation. The lowest treatment was J5 (109 dilution) with a mortality rate of 50% and a successful pupation of 20%. The results of the probit analysis showed that the fastest average lethal time (LT50) value was found in treatment of 107 (J3) which reached 11.11 h. Keywords: Beauveria bassiana, Pathogenicity, Probit analysis, Scirpophaga innotata.
Pelatihan Penggunaan Mesin Sekrap Bagi Mahasiswa di Growth Centre LLDIKTI Wilayah - I Zulfikar, Achmad Jusuf; Supriatno, Supriatno; Candra, Ifan Aulia; Nurdiana, Nurdiana
IRA Jurnal Pengabdian Kepada Masyarakat (IRAJPKM) Vol 1 No 1 (2023): April
Publisher : CV. IRA PUBLISHING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56862/irajpkm.v1i1.53

Abstract

Shaping machine training for students significantly benefits developing technical skills, preparing them for the world of work, and increasing their understanding of manufacturing processes and job safety. A shaping machine is a tool to machine metal surfaces using a reciprocating linear motion. This machine uses a blade moving back and forth to remove a thin metal layer from the work surface and create the desired shape. It is essential to adapt the training method to the needs and characteristics of the participants and provide a safe and conducive environment for learning and practising the use of the shaping machine. Evaluation of technical skills, assessment of theoretical knowledge, and review of the work results of the participants. The experience gained during the training will vary for each participant depending on background, level of expertise, and commitment to learning. The results of this training are expected to increase knowledge and understanding of shaping machines. Participants will learn in-depth about the basic principles of shaping machines, their components, and proper operating techniques.
The Impact of Liquid Organic Fertilizer on Growth and Crop Production of Melon (Cucumis melo L.) Lisdayani; Candra, Ifan Aulia
Jurnal Online Pertanian Tropik Vol. 9 No. 1 (2022): JURNAL ONLINE PERTANIAN TROPIK
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (430.788 KB) | DOI: 10.32734/jopt.v9i1.6880

Abstract

Melon (Cucumis melo L.) is one of the most popular fruit commodities in Indonesia, thanks to its sweet, wonderful flavor, as well as its high nutritional content and nutritional value. Consumer demand for melons is very high, both locally and internationally, although the sugar level of this particular melon is not too sweet. A melon (Cucumis melo L.) is a herbaceous annual plant that grows on vines and is a member of the cucumber family. This study aimed to determine the optimum concentration of cow urine for development (Cucumis melo L.). The experiment used a fully randomized design (CRD) with one factor, namely the concentration of 6-level bio urine, namely B0 = 0 percent bio urine, B1 = 10 percent bio urine, B2 = 20 percent bio urine, B3 = 30 percent bio urine, B4 = 40 percent bio urine, and B5: 50 percent bio urine from 100 ml/plant recommendation. The research findings indicated that application of bio-liquid organic fertilizer (POC) to cow urine may increase: plant length, stem diameter, number of male flowers, and number of female flowers with the best 10 percent POC bio-cow urine. Melon growing can produce 10 percent bio-liquid organic fertilizer (POC) from cow urine.
A Identification of Potency and Restriction for Developing Torbangun Plant (Coleus amboinicus L.): Indonesia Damanik, Kevin Aditya; Ifan, Ifan Aulia Candra; Hasibuan, Syahbudin
Agrifarm : Jurnal Ilmu Pertanian Vol 13 No 2 (2024): Agrifarm
Publisher : Universitas Widya Gama Mahakam

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Coleus amboinicus, dikenal secara lokal sebagai torbangun, merupakan tanaman perdu dari keluarga Lamiaceae yang memiliki batang tebal, daun hijau berbulu, dan aroma khas. Tanaman ini banyak digunakan dalam pengobatan tradisional untuk berbagai tujuan, termasuk meningkatkan produksi ASI dan mengatasi gangguan pencernaan. C. amboinicus memiliki potensi besar dalam pengembangan produk farmasi dan nutraseutikal berkat kandungan fitokimia aktif seperti flavonoid, fenolik, dan minyak esensial. Potensi pengembangan penelitian terletak pada eksplorasi lebih lanjut dari kandungan bioaktif tanaman ini dan mekanisme aksi terapeutiknya. Beberapa contoh pengembangan yang dapat dilakukan antara lain penelitian klinis mengenai efektivitas torbangun dalam terapi antimikroba, antikanker, serta efek imunomodulator. Selain itu, optimasi metode ekstraksi dan identifikasi komponen bioaktif yang lebih efisien juga merupakan area potensial untuk penelitian lanjutan. Namun, pengembangan C. amboinicus juga menghadapi beberapa hambatan, termasuk kurangnya data klinis yang mendukung keamanan penggunaan jangka panjang serta kendala dalam kultivasi massal di luar habitat aslinya. Penelitian yang lebih mendalam diperlukan untuk mengatasi tantangan ini, terutama dalam aspek agronomi, bioteknologi, dan formulasi produk yang sesuai dengan standar farmasi modern.
Morphological, Molecular, and Morphometric Analysis of Aphelenchoides besseyi on Organic Rice (Oryza sativa) Seeds in the Beringin District, Deli Serdang Regency, Indonesia Suswati, Suswati; Azwana, Azwana; Candra, Ifan Aulia; Kuniawati, Fitrianingrum; Siregar, Khofifah Muhaimini; Hasanah, Asmaul; Nasution, Aldy Elvanandar
Makara Journal of Science Vol. 29, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Aphelenchoides besseyi, a nematode, can infect rice resulting in the white shoot disease, which decreases the germina-tion rate and even causes seedling death. A. besseyi has recently been reported to mainly attack the organic rice varie-ties especially Pandanwangi and Ciherang in the Pasar Kawat, Beringin District, Deli Serdang, Indonesia. This research investigated A. besseyi via morphological, molecular, and morphometric approaches. The nematodes were observed in an area of 2000 m2, divided into five sample plots each with an area of 400 m2 on which Pandan Wangi and Ciherang rice were cultivated. Nematode morphology was observed using a stereo microscope at a 10–100x magnification. Mo-lecular identification employed PCR, followed by sequencing and phylogenetic analysis. This nematode possessed typ-ical morphological characteristics namely a longer female body (457.07–738.86 µm) than males (385.23–505.29 µm), and cured spicules, 17 to 21 µm long. The tail was ribbon-shaped with a tapered tip that had a mucrone with 2–4 points. Sequencing and phylogenetic analysis revealed that A. besseyi isolated from Indonesia (Deli Serdang/North Sumatra) was closely related to those from China, India, Russia, Taiwan, and Portugal with a 98% homology level.
Efektifitas Penambahan Berbagai Pengawet Alami terhadap Preservasi dan Preferensi Nira pada Masyarakat Kabupaten Deli Serdang Basrah, Asman; Candra, Ifan Aulia; Aziz, Rizal
Teknotan: Jurnal Industri Teknologi Pertanian Vol 19, No 1 (2025): TEKNOTAN, April 2025
Publisher : Fakultas Teknologi Industri Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jt.vol19n1.2

Abstract

Penelitian ini bertujuan untuk pengaruh jenis dan konsentrasi pengawet alami terhadap preservasi dan preferensi nira yang dihasilkan. Penelitian ini dilakukan di kecamatan Galang Kabupaten Deli Serdang, Desa Nogo Rejo yang berlokasi dengan luas tanaman aren 3,35 ha, dengan produksi 3,42 ton. Penelitian ini menggunakan pengawet alami ekstrak daun jambu (B1) ekstrak daun salam (B2) dan esktrak kulit kayu raru (B3) dengan penggunaan konsentrais 1 %, 2 % dan 3 %.  Data dianalisis secara deskriptif.  Hasil penelitian menunjukkan jenis pengawet alami dapat meningkatkan preservasi dan preferensi nira pada masyarakat di Kabupaten Deli Serdang. Penggunaan ekstrak kayu raru menghasilkan raru dengan kualitas yang lebih baik dibandingkan dengan ekstrak daun jambu dan daun salam.  Hal ini dapat dilihat dari warna, bau, rasa dan penampakan nira selama penyimpanan.  Pada penggunaan esktrak kayu raru nira masih memiliki kualitas yang baik hingga penyimpanan 78 jam, sedangkan pada penggunaan ekstrak daun jambu dan daun salam kualitas nira hanya dapat bertahan pada penyimapan 66 jam. Konsentrasi pengawet dapat meningkatkan preservasi dan preferensi nira pada masyarakat di Kabupaten Deli Serdang. Penggunaan konsentrasi pengawet alami sebesar 3 % menghasilkan kualitas nira yang lebih baik dibandingkan dengan konsentrasi 2 % dan 1 %. Pada penggunaan pengawet alami dengan konsentrasi 1 dan 2 %, nira hanya dapat bertahan dengan penyimpanan selama 54 dan 66 jam, sedangkan pada penggunaan konsentrasi 3 %, nira masih dapat bertahan hingga penyimpanan 78 jam.