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Anti-Aging Potential and Quercetin Determination of Melastoma malabathricum L. Leaves Extract Amalia, Thia
Pharmaceutical Journal of Indonesia Vol. 10 No. 1 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.010.01.6

Abstract

Background: Melastoma malabathricum L. is a wild shrub that traditionally used in South-East Asia as wound healing. Plant extracts contain phenolic, flavonoid and tannin. The leaves extract also has many pharmacological activity but the anti-aging activity of the leaves extract has not been studied. Methods: The leaves of M. malabathricum was defatted with chloroform and then refluxed by ethanol. Quercetin content of the leaves extract was determined by HPLC. Anti-aging activity was evaluated by anti-elastase, and anti collagenase inhibitor activity of the leaves extract by a fluorometric method. Results: Percentage yield of the M. malabathricum leaves extract was 16.53% w/w. Quercetin content of the leaves extract was 9.20 mg/g extract. The leaves extract of M. malabathricum L. has anti-elastase and anti collagenase activity with IC50 80.39±2.36 ppm and 63.3±3.32 ppm, respectively. Conclusions: M. Malabathricum leaves extract was potential as an anti-aging cosmetic raw material.
Anti-Aging Potential and Quercetin Determination of Melastoma malabathricum L. Leaves Extract Amalia, Thia
Pharmaceutical Journal of Indonesia Vol. 10 No. 1 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.010.01.6

Abstract

Background: Melastoma malabathricum L. is a wild shrub that traditionally used in South-East Asia as wound healing. Plant extracts contain phenolic, flavonoid and tannin. The leaves extract also has many pharmacological activity but the anti-aging activity of the leaves extract has not been studied. Methods: The leaves of M. malabathricum was defatted with chloroform and then refluxed by ethanol. Quercetin content of the leaves extract was determined by HPLC. Anti-aging activity was evaluated by anti-elastase, and anti collagenase inhibitor activity of the leaves extract by a fluorometric method. Results: Percentage yield of the M. malabathricum leaves extract was 16.53% w/w. Quercetin content of the leaves extract was 9.20 mg/g extract. The leaves extract of M. malabathricum L. has anti-elastase and anti collagenase activity with IC50 80.39±2.36 ppm and 63.3±3.32 ppm, respectively. Conclusions: M. Malabathricum leaves extract was potential as an anti-aging cosmetic raw material.
Workshop dan Edukasi Pemanfaatan Herbal sebagai Upaya Peningkatan Kesehatan Keluarga pada Anggota PKK: Workshop and Education on Herbal Utilization to Enhance Family Health for PKK Members Ebtavanny, Tamara Gusti; Hariadini, Ayuk Lawuningtyas; Firdaus, Favian Rafif; Achmad, Anisyah; Amalia, Thia; Nabilah, Varna Amalia; Fauzan, Evan; Azis, Umar Abdul; Wibowo, Andriani Abigail
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 4 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i4.8709

Abstract

The Family Welfare Empowerment (PKK) is a community group dedicated to fostering family and societal well-being, with health being one of its key focus areas. PKK members are pivotal in enhancing family immunity, particularly during heightened risk from bacterial, viral, and other infections. The community's preference for traditional medicine, which has been empirically proven to be safe and effective, such as *Andrographis paniculata* (sambiloto) and *Curcuma longa L.* (turmeric), serves as a viable solution for boosting family immunity. This program aimed to provide education and workshops to 50 PKK members in Kendalpayak Village through education sessions, pre-and post-tests, a herbal drink preparation workshop, and follow-up consultations. The education covered topics on the immune system, the definition and application of traditional medicine, and the rational use of herbal remedies. The program results revealed a significant improvement in participants' knowledge, with average pre-test scores of 81.71 rising to 93.90 in post-tests, reflecting a 12.19% increase. Furthermore, the proportion of participants with "Good" knowledge levels rose from 75.61% to 92.68%. The workshop successfully trained participants in practical herbal preparation by demonstrating the production of three types of immune-boosting herbal drinks, supported by educational materials that had obtained intellectual property rights. Participant satisfaction with the program was notably high, averaging 96.06%. These results demonstrate the program's tangible benefits in enhancing community knowledge and skills, potentially supporting family health and well-being in the future.
EDUKASI KADER POSYANDU BERDASARKAN SAINTIFIKASI JAMU UNTUK SWAMEDIKASI MENGGUNAKAN OBAT TRADISIONAL Amalia, Thia; Nurrahmah, Queen Intan; Khasanah, Uswatun; Widarson, Widarson; Fatkhiya, Norma Inayatul; Sutiyono, Bershiella Amandari; Azzahra, Sarrah Syifa; Maitri, Ni Made Ajeng Gayatri Paramitha; Prameswari, Putri Indrasti; Mukaromah, Faizatul
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 2 (2025): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i2.29808

Abstract

Abstrak: Penuaan penduduk global menimbulkan tantangan besar bagi kesehatan, terutama bagi lansia yang rentan terhadap penyakit tidak menular. Di Indonesia, pengobatan tradisional semakin banyak digunakan, termasuk di Desa Pojok, Kecamatan Dampit, Kabupaten Malang, yang memiliki populasi lansia cukup tinggi. Namun, masih terdapat keterbatasan dalam pemahaman masyarakat, terkait pemanfaatan obat tradisional yang aman dan berbasis ilmiah. Kegiatan ini bertujuan untuk meningkatkan pengetahuan dan keterampilan kader posyandu dalam memanfaatkan obat tradisional berbasis saintifikasi jamu. Metode yang diterapkan meliputi sosialisasi, penyuluhan, serta pelatihan praktis kepada 33 kader posyandu, disertai evaluasi pemahaman melalui 10 butir soal pre-test dan post-test. Kegiatan dibagi menjadi dua tahap, yaitu skrining kesehatan untuk melipat pola penyakit yang selanjutnya menjadi dasar penyuluhan kepada kader posyandu. Hasil kegiatan menunjukkan peningkatan pemahaman dari 52% menjadi 85%, yang mencerminkan efektivitas intervensi edukasi dalam meningkatkan keterampilan kader posyandu terkait pengolahan dan pemanfaatan obat tradisional yang aman dan rasional.Abstract: The aging global population poses significant health challenges, particularly for the elderly. In Indonesia, traditional medicine is increasingly utilized, including in Pojok Village, Dampit District, Malang Regency, which has a relatively high elderly population. However, there are still limitations in public understanding regarding the safe and scientific use of traditional medicine. This community service aimed to enhance the knowledge and skills of health workers, particularly posyandu cadres, in managing elderly health through scientific-based traditional medicine. The method involved socialization, counseling, and workshop on making herbal medicine, attended by 33 posyandu cadres and 71 elderly participants. The program is divided into two stages: health screening to identify disease patterns, which then serve as the basis for counseling the cadres. Pre-test and post-test evaluations showed a significant improvement in understanding the benefits and safe use of traditional medicine, increasing from 52% to 85%. These results indicate the success in enhancing the participants' skills in utilizing traditional medicine for elderly health. This initiative is expected to contribute to the improvement of community-based healthcare services through the safe and rational use of traditional medicine.