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All Journal PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Pharmaceutical Journal of Indonesia Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang
Amalia, Thia
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Anti-Aging Potential and Quercetin Determination of Melastoma malabathricum L. Leaves Extract Amalia, Thia
Pharmaceutical Journal of Indonesia Vol. 10 No. 1 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.010.01.6

Abstract

Background: Melastoma malabathricum L. is a wild shrub that traditionally used in South-East Asia as wound healing. Plant extracts contain phenolic, flavonoid and tannin. The leaves extract also has many pharmacological activity but the anti-aging activity of the leaves extract has not been studied. Methods: The leaves of M. malabathricum was defatted with chloroform and then refluxed by ethanol. Quercetin content of the leaves extract was determined by HPLC. Anti-aging activity was evaluated by anti-elastase, and anti collagenase inhibitor activity of the leaves extract by a fluorometric method. Results: Percentage yield of the M. malabathricum leaves extract was 16.53% w/w. Quercetin content of the leaves extract was 9.20 mg/g extract. The leaves extract of M. malabathricum L. has anti-elastase and anti collagenase activity with IC50 80.39±2.36 ppm and 63.3±3.32 ppm, respectively. Conclusions: M. Malabathricum leaves extract was potential as an anti-aging cosmetic raw material.
Anti-Aging Potential and Quercetin Determination of Melastoma malabathricum L. Leaves Extract Amalia, Thia
Pharmaceutical Journal of Indonesia Vol. 10 No. 1 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.010.01.6

Abstract

Background: Melastoma malabathricum L. is a wild shrub that traditionally used in South-East Asia as wound healing. Plant extracts contain phenolic, flavonoid and tannin. The leaves extract also has many pharmacological activity but the anti-aging activity of the leaves extract has not been studied. Methods: The leaves of M. malabathricum was defatted with chloroform and then refluxed by ethanol. Quercetin content of the leaves extract was determined by HPLC. Anti-aging activity was evaluated by anti-elastase, and anti collagenase inhibitor activity of the leaves extract by a fluorometric method. Results: Percentage yield of the M. malabathricum leaves extract was 16.53% w/w. Quercetin content of the leaves extract was 9.20 mg/g extract. The leaves extract of M. malabathricum L. has anti-elastase and anti collagenase activity with IC50 80.39±2.36 ppm and 63.3±3.32 ppm, respectively. Conclusions: M. Malabathricum leaves extract was potential as an anti-aging cosmetic raw material.
Workshop dan Edukasi Pemanfaatan Herbal sebagai Upaya Peningkatan Kesehatan Keluarga pada Anggota PKK: Workshop and Education on Herbal Utilization to Enhance Family Health for PKK Members Ebtavanny, Tamara Gusti; Hariadini, Ayuk Lawuningtyas; Firdaus, Favian Rafif; Achmad, Anisyah; Amalia, Thia; Nabilah, Varna Amalia; Fauzan, Evan; Azis, Umar Abdul; Wibowo, Andriani Abigail
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 4 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i4.8709

Abstract

The Family Welfare Empowerment (PKK) is a community group dedicated to fostering family and societal well-being, with health being one of its key focus areas. PKK members are pivotal in enhancing family immunity, particularly during heightened risk from bacterial, viral, and other infections. The community's preference for traditional medicine, which has been empirically proven to be safe and effective, such as *Andrographis paniculata* (sambiloto) and *Curcuma longa L.* (turmeric), serves as a viable solution for boosting family immunity. This program aimed to provide education and workshops to 50 PKK members in Kendalpayak Village through education sessions, pre-and post-tests, a herbal drink preparation workshop, and follow-up consultations. The education covered topics on the immune system, the definition and application of traditional medicine, and the rational use of herbal remedies. The program results revealed a significant improvement in participants' knowledge, with average pre-test scores of 81.71 rising to 93.90 in post-tests, reflecting a 12.19% increase. Furthermore, the proportion of participants with "Good" knowledge levels rose from 75.61% to 92.68%. The workshop successfully trained participants in practical herbal preparation by demonstrating the production of three types of immune-boosting herbal drinks, supported by educational materials that had obtained intellectual property rights. Participant satisfaction with the program was notably high, averaging 96.06%. These results demonstrate the program's tangible benefits in enhancing community knowledge and skills, potentially supporting family health and well-being in the future.
Co-Authors ANISYAH ACHMAD Ayuk Lawuningtyas Hariadini Azis, Umar Abdul Fauzan, Evan Firdaus, Favian Rafif Nabilah, Varna Amalia Tamara Gusti Ebtavanny Wibowo, Andriani Abigail