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Theoretical Evaluation of Michelia Species’ Bioactive Compounds and Theraupetic Potential: A Literature Review Oktaviana, Nurul; Isnaini, Nadia; Harnelly, Essy; Zulkarnain, Zulkarnain; Muhammad, Syaifullah; Misrahanum, Misrahanum
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 2 (2023): December 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i2.12

Abstract

Michelia alba is a multifunctional plant found in Indonesia and is also called magnolia. Michelia alba is a tree known for its essential oil, which has long been used as a fragrance ingredient in perfumes and cosmetics. The potential of M. alba is immense for use in the prevention and treatment of disease as well as the management of human health and wellness. To date, there have been few publications regarding the biological activities of M. alba, focusing on tyrosinase inhibitory, antibacterial, antidiabetic, anti-inflammatory and antioxidant activities. However, M. alba may have additional undiscovered biological activities associated with its bioactive compounds. The purpose of this literature review research is to find out the bioactive compounds and therapeutic potential of the M. alba plant through literature searches that can be a reference for further research. The literature review method is carried out by searching and collecting data from literature sources obtained from several national and international journals that review bioactive compounds and the therapeutic potential of M. alba plants. Based on the literature review, it was found that M. alba has bioactive compounds namely linalool (72.8 flower oil and 80.1% leaf oil), α-terpineol (6.04% flower oil), phenylethyl alcohol (2.58% flower oil), β-pinene (2.39% flower oil) and geraniol (1, 23%) which have therapeutic activities such as mental health disorders, anticancer, anti-inflammatory, antihypertensive, antidiabetic, antihyperlipidemia, antimaagic, antidiarrheal, anti-asthma, and antihyperpigmentation. In traditional medicine it is used to treat fever, syphilis, gonorrhea and malaria, bronchitis, prostatitis, cancer, headache, sinusitis, cough, inflammation of the respiratory tract, chest fullness, flatulence, nausea, body and underarm odor, and vaginal discharge.
Trends in Formulation of Night Cream Containing Essential Oil Isnaini, Nadia; Faradhila, Jihan; Maysarah, Hilda; Prajaputra, Vicky; Harnelly, Essy; Zulkarnain, Zulkarnain; Maryam, Siti; Muhammad, Syaifullah; Haditiar, Yudi; Desiyana, Lydia Septa; Sari, Febia
Journal of Patchouli and Essential Oil Products JOURNAL OF PATCHOULI AND ESSENTIAL OIL PRODUCT : VOLUME 2, ISSUE 2 (DECEMBER 2023)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jpeop.v2i2.36090

Abstract

Night creams play a pivotal role in skincare routines by safeguarding against nocturnal moisture loss and promoting a smooth, wrinkle-free complexion. However, conventional formulations of night creams often incorporate synthetic active substances, potentially leading to adverse effects over prolonged use. Addressing this concern involves substituting these synthetic compounds with natural ingredients, particularly essential oils, renowned for their diverse skincare benefits encompassing anti-acne, anti-aging, anti-wrinkle, and moisturizing properties. A systematic review was conducted to establish a foundation for future investigations, focusing on the integration of essential oils in night cream formulations. The outcomes revealed that various night cream formulations, enriched with essential oils derived from natural ingredients such as rosemary oil, camellia oil, clove oil, geranium oil, lemongrass oil, rosehip oil, and sandalwood oil, demonstrate remarkable efficacy in preserving skin moisture. The versatility of essential oils has been showcased in the development of night creams, boasting diverse beneficial effects across skincare concerns. This systematic investigation highlights the potential of essential oil-based night creams, which have recently gained traction in the global market. The burgeoning introduction of these products signifies an escalating demand for such skincare solutions and points towards promising prospects for future advancements in essential oil-based night creams.Keywords: essential oils, formulation, natural product chemistry, night cream, patchouli oil, skincare
Antiaging Mechanism of Natural Plant Sources: A Potential Current Product Nafissa, Naja; Isnaini, Nadia; Desiyana, Lydia Septa; Prajaputra, Vicky; Harnelly, Essy; Zulkarnain, Zulkarnain; Maryam, Siti
Journal of Patchouli and Essential Oil Products JOURNAL OF PATCHOULI AND ESSENTIAL OIL PRODUCT : VOLUME 2, ISSUE 2 (DECEMBER 2023)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jpeop.v2i2.37929

Abstract

The aging process is a multifaceted phenomenon influenced by various intrinsic and extrinsic factors. Oxidative stress, stemming from an imbalance between intracellular antioxidants and the excessive production of reactive oxygen species, is known to accelerate aging. Skin aging manifests through wrinkles, fine lines, and dark spots that become visible on the skin's surface. In modern times, cosmetics are not just associated with beauty but also with achieving younger-looking skin. There is a growing demand for anti-aging cosmetics formulated with natural ingredients. Natural anti-aging ingredients, such as plant extracts and antioxidants, including secondary compounds like phenols, flavonoids, alkaloids, tannins, anthocyanins, and coumarins, have gained popularity due to their potential to counteract the effects of oxidative stress and inflammation. These compounds play a pivotal role in neutralizing free radicals, oxidative stress, promoting collagen and skin elasticity, as well as addressing pigmentation and serving as natural skin-whitening agents. This research aims to explore the anti-aging mechanism of natural lant sources in making potential cosmetic Products.Keywords:antiaging, cosmetics, natural cosmetics, mechanism natural cosmetics
A Systematic Review: Formulation of Facial Wash Containing Essential Oil Syaharani, Cut Puspita Salsabila; Isnaini, Nadia; Harnelly, Essy; Prajaputra, Vicky; Maryam, Siti; Gani, Fadli A.
Journal of Patchouli and Essential Oil Products JOURNAL OF PACTHOULI AND ESSENTIAL OIL PRODUCT : VOLUME 2, ISSUE 1 (JUNE 2023)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jpeop.v2i1.32261

Abstract

Facial wash is a major need of the community because it is very helpful in removing dirt, dust, dead skin cells, oil, residual cosmetics and provides moisture to the skin. In general, the face wash used by the community is classified as a synthetic product that can damage the skin, one alternative to avoid this by using natural ingredients such as essential oils. Essential oils have many benefits, including as anti-acne, antibacterial, and antioxidant. Therefore, a systematic review was conducted regarding the formulation of essential oils as a face wash that can be a reference in future research. The systematic review method was carried out by collecting data from various literature sources obtained from several research journals that have been published both nationally and internationally accredited reviewing face wash cosmetics containing essential oils. Based on the systematic review, it was found that there are several face wash formulations containing essential oils of patchouli oil, tea tree oil, jasmine oil, cinnamon oil, black cumin seed oil, basil oil, ylang-ylang oil, peppermint oil, turmeric oil, lemongrass oil, lavender oil, and tangerine oil.
Hybrid Handwash with Silver Nanoparticles from Calotropis gigantea Leaves and Patchouli Oil: Development and Properties Salsabila, Indah; Khairan, Khairan; Kemala, Pati; Idroes, Ghifari Maulana; Isnaini, Nadia; Maulydia, Nur Balqis; El-Shazly, Mohamed; Idroes, Rinaldi
Malacca Pharmaceutics Vol. 2 No. 2 (2024): September 2024
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/mp.v2i2.206

Abstract

When washing hands, handwashing is one way to prevent diseases caused by bacteria such as Staphylococcus aureus and Escherichia coli, the most common bacteria that can cause infections. The production of handwash utilizing silver nanoparticles as an active antibacterial agent remains a relatively infrequent practice. The synthesis of silver nanoparticles from the leaves of Calotropis gigantea, which grows in the geothermal area of Ie Seu-um Aceh Besar, has been carried out using the green synthesis method and hybrid green synthesis with patchouli oil. Handwash with active ingredients such as silver nanoparticles was successfully formulated, evaluated, and tested against S. aureus and E. coli. The organoleptic characteristics, pH, viscosity, foam height measurements, density, irritation, and antibacterial activity against S. aureus and E. coli were evaluated. The results showed that the organoleptic properties of the handwash with silver nanoparticles were not changed during a 30-day storage period, with pH values in the range of 9.7-10.3, and did not cause irritation upon using silver nanoparticle handwash. The best formula for handwashing with silver nanoparticles in inhibiting the growth of S. aureus and E. coli bacteria was F2, with inhibition zones of 12.9 ± 2.85 mm and 10.95 ± 0.8 mm, respectively. The formulated handwash with silver nanoparticles met the requirements of good liquid soap according to the Indonesian National Standard (SNI) with potent antibacterial activity.
Identifikasi Alat Tangkap Perikanan Ramah Lingkungan di Pelabuhan Perikanan Samudera Lampulo, Banda Aceh Prajaputra, Vicky; Isnaini, Nadia; Miraza, Adithya Zulfadli
Akuatiklestari Vol 6 No 2 (2023): Jurnal Akuatiklestari
Publisher : Program Studi Manajemen Sumberdaya Perairan, Fakultas Ilmu Kelautan dan Perikanan, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/akuatiklestari.v6i2.5579

Abstract

Pelabuhan Perikanan Samudera Lampulo (PPSL) telah menjadi salah satu pelabuhan perikanan yang berkontribusi signifikan dalam sektor perikanan tangkap di wilayah Banda Aceh. Para nelayan mengandalkan berbagai alat penangkapan ikan untuk mendapatkan hasil yang maksimal. Tujuan utama penelitian ini mengidentifikasi alat tangkap perikanan eco-friendly berbasis Code of Conduct Responsible for Fisheries (CCRF) di PPSL, Banda Aceh. Penelitian dilakukan secara observasi dan wawancara kepada responden. Hasil observasi menunjukkan bahwa terdapat tiga jenis alat tangkap yang digunakan oleh para nelayan, yaitu pukat cincin, pancing ulur, dan pancing rawai. Alat tangkap jenis pancing ulur dan pancing rawai menjadi prioritas layak beroperasi di PPSL dengan perolehan nilai tingkat keramahan lingkungan masing-masing sebesar 35 dan 33, sehingga kedua alat tangkap tersebut tergolong ke dalam kategori sangat eco-friendly. Sementara pukat cincin masuk ke dalam kategori alat tangkap kurang eco-friendly dengan nilai sebesar 26. Meskipun demikian, pukat cincin masih layak beroperasi di PPSL karena memenuhi kriteria CCRF dengan baik, tidak begitu mengancam lingkungan dan perikanan secara keberlanjutan.
Edukasi Kosmetika Aman: Upaya Meningkatkan Pengetahuan Warga Gampong Kopelma Darussalam Maryam, Siti; Isnaini, Nadia; Prajaputra, Vicky; Ulfa, Safra; Raihanylkhairi
Jurnal Pengabdian Magister Pendidikan IPA Vol 7 No 4 (2024): Oktober-Desember 2024
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v7i4.9130

Abstract

The use of safe cosmetics has become an important concern among Indonesian society, especially with the rise of illegal cosmetic products containing hazardous materials such as mercury and hydroquinone. This community service activity aims to increase the knowledge of the Kopelma Darussalam Village community regarding safe cosmetics through education about the "Cek KLIK" method (Packaging, Label, Distribution Permit, Expiration). The methods used include socialization, distribution of educational brochures, and skin analysis using a skin analyzer. The results of this activity showed an increase in public understanding of cosmetic safety, as shown by the increase in post-test results compared to pre-test. The conclusion of this activity is that public education with interactive and practical methods has proven effective in increasing public awareness of the importance of safe cosmetics.
Hybrid function of light fraction patchouli oil in hair care formulations for effective hair and anti-dandruff treatment Isnaini, Nadia; Muhammad, Syaifullah; Prajaputra, Vicky; Indra, Indra; Sufriadi, Elly; Ernawati, Ernawati; Riski, Cantika D.
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1622

Abstract

Hair issues, such as hair loss and dandruff, pose significant challenges in hair care. Patchouli oil, rich in bioactive components, has emerged as a promising candidate for addressing these concerns. The aim of this study was to investigate the hybrid functionality of fractionated patchouli oil in hair care formulations designed to promote hair growth and control dandruff caused by Malassezia globosa. Crude patchouli oil (CPO) was fractionated to enhance its efficacy, producing light fraction patchouli oil (LFPO), which was then characterized using gas chromatography-mass spectrometry (GC-MS) analysis. Hair tonic formulations containing three different LFPO concentrations (0.5%, 1.0%, and 1.5%) were developed and evaluated for stability, pH, viscosity, and antifungal activity against M. globosa. The results showed that LFPO contained 2.51% acid number, 0.70% ester number, 0.71 mg/kg iron content, and 25.88% patchoulol. The formulations exhibited stable physicochemical properties, with pH levels of 5.36–5.51 and viscosity ranging from 3.94 to 4.08 centipoise (cP), suitable for hair tonic applications. Formulation of 1.5% LFPO demonstrated the strongest antifungal activity, producing a 31.18±1.37 mm inhibition zone against M. globosa, surpassing ketoconazole (21.72±0.28 mm), suggesting potential as a natural antifungal agent. Histological analysis in rabbits revealed that 1.5% LFPO formulation reduced epidermal cell shedding, increased hair length by 41.6±0.35 mm after six weeks, and promoted dense hair follicle growth. This research provides a foundation for developing natural, effective, and stable hair care formulations. Despite these promising results, the efficacy and safety of LFPO formulations in humans remain unexplored. Therefore, a clinical human trial is necessary to assess skin tolerance, irritation risks, and long-term effects under real-world conditions.
Formulation and Evaluation of O/W Body Cream Containing Patchouli Oil (Pogostemon cablin Benth.) and Drumstick Oil (Moringa oleifera) as Potential Moisturizing Agent Isnaini, Nadia; Prajaputra, Vicky; Maryam, Siti
Jurnal Penelitian Pendidikan IPA Vol 9 No 10 (2023): October
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i10.4292

Abstract

Various compounds and extracts obtained from a wide variety of plants can be employed as natural antioxidants in cosmetics applications. Patchouli oil (Pogostemon cablin Benth.) and drumstick oil (Moringa oleifera) have the ability to fight free radicals and keep skin hydrated, making them excellent candidates for usage as an active component in cosmetic goods like body cream. This research aims to determine the physical quality of a body cream formulation by subjecting it to an accelerated stability test technique for seven cycles. The preparation was evaluated in each cycle, and the results were analyzed using student's t-test. The evaluation results of body cream preparation showed that there was no significant difference (p>0.05) in the preparation during each cycle. As a result, the formulation of the body cream remained stable throughout the storage term of at least six months, which indicates that it can be utilized for an entire year when kept at room temperature. After two weeks of application on dry skin, it was demonstrated that the formulation had the capacity to increase the amount of moisture contained in the skin (from 30% to 60%). In conclusion, the formulation is potentially produced as commercial cosmetic product in the future.
Development of Hand Sanitizer and Aromatherapy Perfume from Active Components of Patchouli Oil at MSME Ata Gampong Peurada: Pengembangan Hand sanitizer dan Parfum Aromaterapi dari Komponen Aktif Minyak Nilam pada UMKM Ata Gampong Peurada Muhammad, Syaifullah; Isnaini, Nadia; Indra, Indra; Sufriadi, Elly; Ernawati, Ernawati; Nisa, Khairun; Oktasya, Khairina Mutia; Nurul Akmal, Intan; Prajaputra, Vicky; Gusti Vonna, Adinda
Dinamisia : Jurnal Pengabdian Kepada Masyarakat Vol. 9 No. 4 (2025): Dinamisia: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Lancang Kuning

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31849/q6655035

Abstract

Kelompok Ekonomi Produktif AGP (Ata Gampong Peurada) di Banda Aceh menghadapi kendala dalam pengolahan, pemasaran, dan legalitas produk berbasis minyak nilam. Program ini bertujuan meningkatkan keterampilan anggota pelatihan AGP melalui teknologi purifikasi minyak nilam Aceh menggunakan distilasi molekuler untuk menghasilkan minyak berkualitas tinggi, serta formulasi parfum aromaterapi dan hand sanitizer berbasis fraksi berat dan ringan minyak nilam. Dukungan berupa pengadaan mesin mixer, pengisian otomatis, dan pelatihan pemasaran digital membantu AGP memperluas jangkauan produk melalui e-commerce. Hasil program menunjukkan AGP mampu meningkatkan kapasitas produksi hingga 500 botol, pemasaran melalui tiga platform digital, dan mempersiapkan pendaftaran izin edar serta produk inovasi HKI. Program ini mendukung kemandirian ekonomi masyarakat melalui produk inovatif yang memenuhi standar pasar dan penguatan kapasitas AGP sebagai kelompok usaha profesional.