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Theoretical Evaluation of Michelia Species’ Bioactive Compounds and Theraupetic Potential: A Literature Review Oktaviana, Nurul; Isnaini, Nadia; Harnelly, Essy; Zulkarnain, Zulkarnain; Muhammad, Syaifullah; Misrahanum, Misrahanum
Grimsa Journal of Science Engineering and Technology Vol. 1 No. 2 (2023): December 2023
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v1i2.12

Michelia alba is a multifunctional plant found in Indonesia and is also called magnolia. Michelia alba is a tree known for its essential oil, which has long been used as a fragrance ingredient in perfumes and cosmetics. The potential of M. alba is immense for use in the prevention and treatment of disease as well as the management of human health and wellness. To date, there have been few publications regarding the biological activities of M. alba, focusing on tyrosinase inhibitory, antibacterial, antidiabetic, anti-inflammatory and antioxidant activities. However, M. alba may have additional undiscovered biological activities associated with its bioactive compounds. The purpose of this literature review research is to find out the bioactive compounds and therapeutic potential of the M. alba plant through literature searches that can be a reference for further research. The literature review method is carried out by searching and collecting data from literature sources obtained from several national and international journals that review bioactive compounds and the therapeutic potential of M. alba plants. Based on the literature review, it was found that M. alba has bioactive compounds namely linalool (72.8 flower oil and 80.1% leaf oil), α-terpineol (6.04% flower oil), phenylethyl alcohol (2.58% flower oil), β-pinene (2.39% flower oil) and geraniol (1, 23%) which have therapeutic activities such as mental health disorders, anticancer, anti-inflammatory, antihypertensive, antidiabetic, antihyperlipidemia, antimaagic, antidiarrheal, anti-asthma, and antihyperpigmentation. In traditional medicine it is used to treat fever, syphilis, gonorrhea and malaria, bronchitis, prostatitis, cancer, headache, sinusitis, cough, inflammation of the respiratory tract, chest fullness, flatulence, nausea, body and underarm odor, and vaginal discharge.

Trends in Formulation of Night Cream Containing Essential Oil Isnaini, Nadia; Faradhila, Jihan; Maysarah, Hilda; Prajaputra, Vicky; Harnelly, Essy; Zulkarnain, Zulkarnain; Maryam, Siti; Muhammad, Syaifullah; Haditiar, Yudi; Desiyana, Lydia Septa; Sari, Febia
Journal of Patchouli and Essential Oil Products JOURNAL OF PATCHOULI AND ESSENTIAL OIL PRODUCT : VOLUME 2, ISSUE 2 (DECEMBER 2023)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jpeop.v2i2.36090

Night creams play a pivotal role in skincare routines by safeguarding against nocturnal moisture loss and promoting a smooth, wrinkle-free complexion. However, conventional formulations of night creams often incorporate synthetic active substances, potentially leading to adverse effects over prolonged use. Addressing this concern involves substituting these synthetic compounds with natural ingredients, particularly essential oils, renowned for their diverse skincare benefits encompassing anti-acne, anti-aging, anti-wrinkle, and moisturizing properties. A systematic review was conducted to establish a foundation for future investigations, focusing on the integration of essential oils in night cream formulations. The outcomes revealed that various night cream formulations, enriched with essential oils derived from natural ingredients such as rosemary oil, camellia oil, clove oil, geranium oil, lemongrass oil, rosehip oil, and sandalwood oil, demonstrate remarkable efficacy in preserving skin moisture. The versatility of essential oils has been showcased in the development of night creams, boasting diverse beneficial effects across skincare concerns. This systematic investigation highlights the potential of essential oil-based night creams, which have recently gained traction in the global market. The burgeoning introduction of these products signifies an escalating demand for such skincare solutions and points towards promising prospects for future advancements in essential oil-based night creams.Keywords: essential oils, formulation, natural product chemistry, night cream, patchouli oil, skincare

Antiaging Mechanism of Natural Plant Sources: A Potential Current Product Nafissa, Naja; Isnaini, Nadia; Desiyana, Lydia Septa; Prajaputra, Vicky; Harnelly, Essy; Zulkarnain, Zulkarnain; Maryam, Siti
Journal of Patchouli and Essential Oil Products JOURNAL OF PATCHOULI AND ESSENTIAL OIL PRODUCT : VOLUME 2, ISSUE 2 (DECEMBER 2023)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jpeop.v2i2.37929

The aging process is a multifaceted phenomenon influenced by various intrinsic and extrinsic factors. Oxidative stress, stemming from an imbalance between intracellular antioxidants and the excessive production of reactive oxygen species, is known to accelerate aging. Skin aging manifests through wrinkles, fine lines, and dark spots that become visible on the skin's surface. In modern times, cosmetics are not just associated with beauty but also with achieving younger-looking skin. There is a growing demand for anti-aging cosmetics formulated with natural ingredients. Natural anti-aging ingredients, such as plant extracts and antioxidants, including secondary compounds like phenols, flavonoids, alkaloids, tannins, anthocyanins, and coumarins, have gained popularity due to their potential to counteract the effects of oxidative stress and inflammation. These compounds play a pivotal role in neutralizing free radicals, oxidative stress, promoting collagen and skin elasticity, as well as addressing pigmentation and serving as natural skin-whitening agents. This research aims to explore the anti-aging mechanism of natural lant sources in making potential cosmetic Products.Keywords:antiaging, cosmetics, natural cosmetics, mechanism natural cosmetics

A Systematic Review: Formulation of Facial Wash Containing Essential Oil Syaharani, Cut Puspita Salsabila; Isnaini, Nadia; Harnelly, Essy; Prajaputra, Vicky; Maryam, Siti; Gani, Fadli A.
Journal of Patchouli and Essential Oil Products JOURNAL OF PACTHOULI AND ESSENTIAL OIL PRODUCT : VOLUME 2, ISSUE 1 (JUNE 2023)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jpeop.v2i1.32261

Facial wash is a major need of the community because it is very helpful in removing dirt, dust, dead skin cells, oil, residual cosmetics and provides moisture to the skin. In general, the face wash used by the community is classified as a synthetic product that can damage the skin, one alternative to avoid this by using natural ingredients such as essential oils. Essential oils have many benefits, including as anti-acne, antibacterial, and antioxidant. Therefore, a systematic review was conducted regarding the formulation of essential oils as a face wash that can be a reference in future research. The systematic review method was carried out by collecting data from various literature sources obtained from several research journals that have been published both nationally and internationally accredited reviewing face wash cosmetics containing essential oils. Based on the systematic review, it was found that there are several face wash formulations containing essential oils of patchouli oil, tea tree oil, jasmine oil, cinnamon oil, black cumin seed oil, basil oil, ylang-ylang oil, peppermint oil, turmeric oil, lemongrass oil, lavender oil, and tangerine oil.

Hybrid Handwash with Silver Nanoparticles from Calotropis gigantea Leaves and Patchouli Oil: Development and Properties Salsabila, Indah; Khairan, Khairan; Kemala, Pati; Idroes, Ghifari Maulana; Isnaini, Nadia; Maulydia, Nur Balqis; El-Shazly, Mohamed; Idroes, Rinaldi
Malacca Pharmaceutics Vol. 2 No. 2 (2024): September 2024
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/mp.v2i2.206

When washing hands, handwashing is one way to prevent diseases caused by bacteria such as Staphylococcus aureus and Escherichia coli, the most common bacteria that can cause infections. The production of handwash utilizing silver nanoparticles as an active antibacterial agent remains a relatively infrequent practice. The synthesis of silver nanoparticles from the leaves of Calotropis gigantea, which grows in the geothermal area of Ie Seu-um Aceh Besar, has been carried out using the green synthesis method and hybrid green synthesis with patchouli oil. Handwash with active ingredients such as silver nanoparticles was successfully formulated, evaluated, and tested against S. aureus and E. coli. The organoleptic characteristics, pH, viscosity, foam height measurements, density, irritation, and antibacterial activity against S. aureus and E. coli were evaluated. The results showed that the organoleptic properties of the handwash with silver nanoparticles were not changed during a 30-day storage period, with pH values in the range of 9.7-10.3, and did not cause irritation upon using silver nanoparticle handwash. The best formula for handwashing with silver nanoparticles in inhibiting the growth of S. aureus and E. coli bacteria was F2, with inhibition zones of 12.9 ± 2.85 mm and 10.95 ± 0.8 mm, respectively. The formulated handwash with silver nanoparticles met the requirements of good liquid soap according to the Indonesian National Standard (SNI) with potent antibacterial activity.

Comparative analysis of acids and temperatures in gelatin extraction from the skin of yellowfin tuna (Thunnus albacares) Prajaputra, Vicky; Agustina, Sri; Isnaini, Nadia; Nabila, Agillia; Margolang, Hikma Kasih; Apriani, Sahra; Maqfirah, Siti
Depik Vol 13, No 3 (2024): DECEMBER 2024
Publisher : Faculty of Marine and Fisheries, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13170/depik.13.3.41269

Gelatin, a valuable biopolymer, is commonly derived from animal by-products such as fish skin, providing a sustainable alternative to traditional bovine and porcine sources. The extraction process is influenced by factors like acid type and temperature, which impact both yield and quality. This study aimed to compare the effects of citric acid and acetic acid, at two temperatures (50C and 60C), on the gelatin extracted from yellowfin tuna (Thunnus albacares) skin. The extracted gelatin was evaluated for yield, proximate composition, functional groups using FTIR, and surface morphology through SEM. Results indicated that acetic acid produced a significantly higher yield than citric acid at both temperatures, with the highest yield (10.10%) at 50C and the lowest (2.46%) from citric acid at 60C. Gelatin extracted with acetic acid also had higher protein content and lower moisture and ash levels. FTIR analysis confirmed the presence of characteristic gelatin functional groups, including Amide I, II, and III. SEM images showed a denser and more uniform structure in acetic acid-extracted gelatin, while gelatin extracted with citric acid had a more porous and irregular surface. SDS-PAGE analysis revealed stronger protein bands for gelatin extracted with acetic acid, indicating higher protein content and a more efficient extraction process. Both acid-extracted gelatins showed -chains and -chains, characteristic of denatured collagen. In conclusion, acetic acid proved to be more effective than citric acid in producing higher yield and superior quality gelatin from yellowfin tuna skin. Further studies should assess the gel strength and amino acid composition of the extracted gelatin.Keywords:environmental chemistrybelow waterbiopolymergelatinmarine chemistrywaste valorizationyellowfin tuna

Identifikasi Alat Tangkap Perikanan Ramah Lingkungan di Pelabuhan Perikanan Samudera Lampulo, Banda Aceh Prajaputra, Vicky; Isnaini, Nadia; Miraza, Adithya Zulfadli
Akuatiklestari Vol 6 No 2 (2023): Jurnal Akuatiklestari
Publisher : Program Studi Manajemen Sumberdaya Perairan, Fakultas Ilmu Kelautan dan Perikanan, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/akuatiklestari.v6i2.5579

Pelabuhan Perikanan Samudera Lampulo (PPSL) telah menjadi salah satu pelabuhan perikanan yang berkontribusi signifikan dalam sektor perikanan tangkap di wilayah Banda Aceh. Para nelayan mengandalkan berbagai alat penangkapan ikan untuk mendapatkan hasil yang maksimal. Tujuan utama penelitian ini mengidentifikasi alat tangkap perikanan eco-friendly berbasis Code of Conduct Responsible for Fisheries (CCRF) di PPSL, Banda Aceh. Penelitian dilakukan secara observasi dan wawancara kepada responden. Hasil observasi menunjukkan bahwa terdapat tiga jenis alat tangkap yang digunakan oleh para nelayan, yaitu pukat cincin, pancing ulur, dan pancing rawai. Alat tangkap jenis pancing ulur dan pancing rawai menjadi prioritas layak beroperasi di PPSL dengan perolehan nilai tingkat keramahan lingkungan masing-masing sebesar 35 dan 33, sehingga kedua alat tangkap tersebut tergolong ke dalam kategori sangat eco-friendly. Sementara pukat cincin masuk ke dalam kategori alat tangkap kurang eco-friendly dengan nilai sebesar 26. Meskipun demikian, pukat cincin masih layak beroperasi di PPSL karena memenuhi kriteria CCRF dengan baik, tidak begitu mengancam lingkungan dan perikanan secara keberlanjutan.

Comparative analysis of acids and temperatures in gelatin extraction from the skin of yellowfin tuna (Thunnus albacares) Prajaputra, Vicky; Agustina, Sri; Isnaini, Nadia; Nabila, Agillia; Margolang, Hikma Kasih; Apriani, Sahra; Maqfirah, Siti
Depik Vol 13, No 3 (2024): DECEMBER 2024
Publisher : Faculty of Marine and Fisheries, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13170/depik.13.3.41269

Gelatin, a valuable biopolymer, is commonly derived from animal by-products such as fish skin, providing a sustainable alternative to traditional bovine and porcine sources. The extraction process is influenced by factors like acid type and temperature, which impact both yield and quality. This study aimed to compare the effects of citric acid and acetic acid, at two temperatures (50C and 60C), on the gelatin extracted from yellowfin tuna (Thunnus albacares) skin. The extracted gelatin was evaluated for yield, proximate composition, functional groups using FTIR, and surface morphology through SEM. Results indicated that acetic acid produced a significantly higher yield than citric acid at both temperatures, with the highest yield (10.10%) at 50C and the lowest (2.46%) from citric acid at 60C. Gelatin extracted with acetic acid also had higher protein content and lower moisture and ash levels. FTIR analysis confirmed the presence of characteristic gelatin functional groups, including Amide I, II, and III. SEM images showed a denser and more uniform structure in acetic acid-extracted gelatin, while gelatin extracted with citric acid had a more porous and irregular surface. SDS-PAGE analysis revealed stronger protein bands for gelatin extracted with acetic acid, indicating higher protein content and a more efficient extraction process. Both acid-extracted gelatins showed -chains and -chains, characteristic of denatured collagen. In conclusion, acetic acid proved to be more effective than citric acid in producing higher yield and superior quality gelatin from yellowfin tuna skin. Further studies should assess the gel strength and amino acid composition of the extracted gelatin.Keywords:environmental chemistrybelow waterbiopolymergelatinmarine chemistrywaste valorizationyellowfin tuna

Edukasi Kosmetika Aman: Upaya Meningkatkan Pengetahuan Warga Gampong Kopelma Darussalam Maryam, Siti; Isnaini, Nadia; Prajaputra, Vicky; Ulfa, Safra; Raihanylkhairi
Jurnal Pengabdian Magister Pendidikan IPA Vol 7 No 4 (2024): Oktober-Desember 2024
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v7i4.9130

The use of safe cosmetics has become an important concern among Indonesian society, especially with the rise of illegal cosmetic products containing hazardous materials such as mercury and hydroquinone. This community service activity aims to increase the knowledge of the Kopelma Darussalam Village community regarding safe cosmetics through education about the "Cek KLIK" method (Packaging, Label, Distribution Permit, Expiration). The methods used include socialization, distribution of educational brochures, and skin analysis using a skin analyzer. The results of this activity showed an increase in public understanding of cosmetic safety, as shown by the increase in post-test results compared to pre-test. The conclusion of this activity is that public education with interactive and practical methods has proven effective in increasing public awareness of the importance of safe cosmetics.

Optimalisasi produksi, rebranding, dan strategi pemasaran sabun cuci piring berbasis nilam untuk UMKM di Gampong Peurada, Kota Banda Aceh Isnaini, Nadia; Desiyana, Lydia Septa; Prajaputra, Vicky; Panggabean, Dara Meutia; Rezkina, Cutwan Annura
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 4 (2024): December
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i4.26807

Abstrak Usaha Mikro, Kecil, dan Menengah (UMKM) memainkan peran penting dalam perekonomian Indonesia, namun banyak pelaku UMKM masih belum memahami pentingnya legalitas usaha dan strategi pemasaran yang efektif. Kegiatan pengabdian ini bertujuan untuk meningkatkan pemahaman pelaku UMKM di Gampong Peurada, Kota Banda Aceh, mengenai pendaftaran Hak Kekayaan Intelektual (HKI) merek, perizinan PIRT, serta strategi pemasaran sabun cuci piring berbasis minyak nilam. Kegiatan ini melibatkan 15 peserta yang merupakan ibu rumah tangga dari Gampong Peurada dan dilaksanakan di Training Center USK pada 20-30 September 2024. Metode yang digunakan dalam kegiatan ini meliputi sosialisasi materi terkait legalitas usaha, pemasaran, branding, dan analisis pasar. Selain itu, dilakukan juga penyerahan alat produksi untuk meningkatkan kapasitas produksi UMKM. Evaluasi kegiatan dilakukan melalui pre-test dan post-test untuk menilai peningkatan pemahaman peserta. Hasil kegiatan menunjukkan peningkatan signifikan dalam pemahaman peserta, seperti peningkatan pemahaman mengenai pentingnya kemasan produk (dari 52,63% menjadi 93,33%) dan proses perizinan PIRT (dari 33,33% menjadi 100%). Dukungan ini diharapkan dapat memperkuat daya saing UMKM di Gampong Peurada dalam menghadapi pasar yang lebih luas dan berkelanjutan. Kata kunci: UMKM; legalitas usaha; perizinan PIRT, strategi pemasaran; minyak nilam. AbstractMicro, Small, and Medium Enterprises (MSMEs) are one of the main pillars of Indonesia's economy, playing a crucial role as drivers of national economic growth. However, many MSME actors are still unaware of the importance of business legality, which often results in the circulation of unlicensed products. This service program aimed to enhance the understanding and capacity of MSMEs in Gampong Peurada, Banda Aceh, particularly in optimizing the production, rebranding, and marketing strategies for dishwashing soap based on patchouli oil. The activity was attended by 15 participants, consisting of local housewives, and took place from September 20-30, 2024. The program included training on trademark registration procedures, PIRT licensing, and effective marketing strategies, followed by the provision of production tools to improve the quality and quantity of the dishwashing soap. Pre-test and post-test evaluations showed a significant improvement in participants' knowledge, especially regarding product branding, packaging, and business legality. The program successfully enhanced the participants' skills, providing them with the necessary tools to expand their market reach and improve the competitiveness of their products. Keywords: MSMEs; business legality; PIRT licensing; marketing strategy; patchouli oil

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