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General Description of Glucose and pH in the Urine of Diabetic Mellitus Patients by using Urine Analyzer Permata, Indra; Rasyid, Nur Qadri; Nurhidayat; Wahyuni, Sri; Muawanah
Hayyan Journal Vol. 1 No. 2 (2024): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v1i2.1884

Abstract

Diabetes Mellitus is a chronic disease that occurs due to the failure of the pancreas to produce enough insulin or the body cannot effectively use the insulin produced. One of the complications of diabetes is diabetic ketoacidosis. KAD is an acute complication of Diabetes Mellitus characterized by increased glucose levels. Diabetic Mellitus has higher levels of calcium stones, and uric acid, therefore the pH of the urine of people with Diabetic Mellitus tends to be more acidic. The purpose of the study was to find out the picture of the results of glucose and pH tests in patients with Diabetes Mellitus. The type of research used in this study is laboratory observation. The sampling technique in this study is random sampling. The number of samples in this study was 10 samples, with the Urine Analyzer examination method. The results of the study showed that out of 10 samples studied, 4 samples were found to be glucose-positive, with a pH range of 5 – 7 and 6 samples were not found to be glucose positive with a pH range of 5 - 6.
Analisis Kadar Hidroquinon Pada Sabun Pembersih Wajah Batangan yang Diperjualbelikan di Pasar Rustiah, Waode; Muharram, Andi Fatmawati; Arisanti, Dewi; Muawanah, Muawanah; A. Salim, Indra Permata; Amelia, Kiki Putri
Lontara Journal of Health Science and Technology Vol. 5 No. 2 (2024): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v5i2.450

Abstract

Bar soap is a skin cleansing preparation in solid form made from soap with the addition of desired ingredients, be they natural ingredients or dangerous chemicals. Hydroquinone is a dangerous chemical which, if added excessively to facial cleansing soap, can cause hyperpigmentation on the skin. The use of hydroqunon according to BPOM regulation no. 18 of 2015 is included in the class of hard drugs. Hydroquinone is prohibited from being used because it has dangerous side effects such as skin irritation, facial redness such as a burning sensation and can also cause black spots on the face. This type of research is a laboratory observational study which aims to analyze the hydroquinone levels in bar facial cleansing soap that is sold at the Minasa Maupa market, Sungguminasa, Gowa Regency. The sampling technique was carried out by purposive sampling. The samples were tested qualitatively using the thin layer chromatography method and if positive results were obtained, quantitative analysis was continued using the UV-Vis spectrophotometry method. From the research results of 10 samples of bar facial cleansing soap, 1 sample was positive for containing hydroquinone, indicated by the presence of stains when observed under a UV lamp with an Rf value of 0.427, while the standard Rf value was 0.438. Meanwhile, the other 9 samples did not contain stains so the Rf value could not be calculated. Next, the positive samples were continued with quantitative analysis to obtain a hydroquinone level of 0.013%. The levels obtained were stated to be still below the standards set by BPOM No. 18 of 2015 which amounted to 0.02%
PERBEDAAN IDENTIFIKASI TELUR SOIL TRANSMITTED HELMINTH (STH) PADA SAMPEL FESES ANTARA METODE SEDIMENTASI DENGAN SENTRIFUGASI DAN SEDIMENTASI TANPA SENTRIFUGASI Wahyuni, Sri; Kaswi, Nurwilda; Al Adawiyah, Putri Rabiah; Indra Permata AS
Illea : Journal of Health Sciences, Public Health and Medicine Vol.1, No.2 (2025): Juni 2025
Publisher : Education and Talent Development Center Indonesia (ETDC Indonesia)

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Abstract

Infeksi cacing adalah infeksi yang dapat ditularkan melalui berbagai cara, tergantung pada jenis cacingnya. Jenis cacing ini tersebar luar di seluruh dunia terutama pada daerah iklim tropis dan sub tropis. Penggunaan metode pemeriksaan tinja yang memiliki sensitivitas dan spesifitas tinggi terhadap Soil Transmitted-Helminth sangat penting untuk deteksi dini infeksi tersebut. Metode sedimentasi yang menggunakan prinsip perbedaan berat jenis merupakan alternatif bagi metode natif. Tujuan penelitian ini adalah untuk mengetahui perbedaan signifikan pemeriksaan feses antara metode sedimentasi dengan menggunakan sentrifugasi dan metode sedimentasi tanpa sentrifugasi. Sampel penelitian ini adalah masyarakat di wilayah Dr. Ratulangi, Desa Mario, Kec. Mariso, Kota Makassar. Hasil penelitian menunjukkan bahwa metode sedimentasi dengan menggunakan sentrifugasi tidak lebih besar memprediksi nilai positif daripada metode sedimentasi tanpa menggunakan sentrifugasi (p>0,05). Metode sedimentasi dengan sentrifugasi adalah metode yang paling baik digunakan sebagai alternatif metode natif dalam hal mendeteksi penyakit Soil-Transmitted Helminth.
Eksplorasi Senyawa Kompleks Vanadium Sebagai Agen Terapi: A Mini Review Indra Permata
Illea : Journal of Health Sciences, Public Health and Medicine Vol. 1 No. 1 (2025): Februari 2025
Publisher : Education and Talent Development Center Indonesia (ETDC Indonesia)

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Abstract

Kompleks vanadium telah menarik perhatian luas dalam penelitian medis karena sifat biologisnya yang menjanjikan sebagai agen terapeutik. Kompleks ini menunjukkan aktivitas farmakologis yang beragam, termasuk antidiabetik, antikanker, antivirus, antiinflamasi, antibakteri, dan neuroprotektif. Mekanisme kerja terapeutiknya melibatkan modulasi jalur sinyal seluler, penghambatan enzim spesifik, induksi apoptosis, serta pengurangan spesies oksigen reaktif (ROS). Sebagai agen antidiabetik, vanadium meningkatkan sensitivitas insulin dan menghambat enzim glukosa-6-fosfatase. Dalam terapi kanker, kompleks vanadium menginduksi apoptosis dan menghambat proliferasi sel tumor melalui jalur MAPK dan NF-κB. Kemampuannya untuk menghambat replikasi virus dan merusak struktur bakteri menunjukkan potensinya sebagai agen antivirus dan antibakteri. Selain itu, kompleks vanadium menekan peradangan dengan memodulasi sitokin proinflamasi serta memberikan perlindungan neuroprotektif terhadap stres oksidatif. Dengan toksisitas yang dapat dikelola melalui modifikasi kimia, kompleks vanadium menawarkan peluang besar dalam terapi multidimensi, meskipun diperlukan penelitian lebih lanjut untuk aplikasi klinis yang aman dan efektif.
The Relationship Between Knowledge and Attitudes of Nursing Students Towards Premarital Sex in Indonesia Br Saragih, Dameria; Mailintina, Yurita; Panjaitan, Ribka Sabarina; Silaban, Merri; A. Salim, Indra Permata
Celebes Nursing Journal Vol. 1 No. 1 (2024): June 2024
Publisher : MALATA SAINS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70848/cnj.v1i1.2

Abstract

Introduction: Nursing students, as prospective health workers, have a very important role in providing education and services to the community related to healthy sexual practices. The knowledge and attitudes of nursing students towards premarital sex in Indonesia are relevant subjects to be researched. Objectives: This study aims to fill the knowledge gap by investigating the knowledge and attitudes of nursing students towards premarital sex in Indonesia. Methods: This study used quantitative analytical methods with a cross sectional design. This research was conducted on 5 campuses organizing nursing education in Indonesia. Results: from 230 respondents, the mean value of sex was 1.07, the age of respondents was 1.94, knowledge was 1.94 and attitude was 1.85, then the Standard Error value of 0.022, 0.016, 0.010 and .0.29, the median value of 1.00, 2.00, 2.00 and 2.00, the value of Std Deviation 0.330, 0.240, 0.146 and 0.443, the variance value of 0.109, 0.057, 0.021 and 0.196 and the value of range 3,  1.1 and 2 of each variable. The majority have good knowledge (176.1) and sufficient attitudes (180.0). However, the number of respondents with less knowledge (5.0) and good attitude (41.1) is relatively less. The chi-square test showed a p-value of 0.000, showing a significant relationship between nursing students' knowledge and attitudes toward premarital sex. Conclusion: In this study, it was concluded that the knowledge and attitudes of nursing students have a close relationship. There is good knowledge so that students can control negative attitudes or actions towards premarital sex.