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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Health and Medical Journal
Pradestine, Sesia
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Koinsidensi Vaginosis Bakterial pada Pasien dengan Kandidiasis Vulvovaginalis Kronis Pradestine, Sesia; Mawardi, Prasetyadi
Health and Medical Journal Vol 6, No 3 (2024): HEME September 2024
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v6i3.1620

Abstract

Vaginosis bakterial (VB) dan kandidiasis vulvovaginal (KVV) adalah infeksi vagina yang umum terjadi dengan etiologi yang berbeda, namun dapat terjadi bersamaan dan mempersulit pengobatan. Ketidakseimbangan dalam mikrobiota vagina menjadi ciri khas VB, sedangkan KVV adalah infeksi jamur yang disebabkan oleh Candida spp. Interaksi antara infeksi ini dapat mempengaruhi hasil pengobatan.  Kami melaporkan seorang wanita berusia 19 tahun yang datang dengan keputihan berwarna putih kental, berbau, dan gatal. Dia memiliki riwayat gejala yang berulang dan sering menggunakan antibiotik. Pemeriksaan fisik menunjukkan beberapa papula dan cairan putih susu. Pemeriksaan mikroskopis menunjukkan adanya pseudohifa, sel tunas, dan bakteri batang gram negatif dengan sel petunjuk. Pasien didiagnosis dengan VB bersamaan dengan KVV kronis dan diobati dengan metronidazol dan flukonazol, diikuti dengan itrakonazol, yang menghasilkan perbaikan. Terjadinya VB dan KVV secara bersamaan mempersulit pengobatan karena mikrobiota vagina yang berubah. Antibiotik untuk VB dapat meningkatkan pertumbuhan Candida, yang menyebabkan KVV. KVV kronis pada pasien membutuhkan terapi antijamur yang lebih lama. Memahami interaksi antara VB dan KVV sangat penting untuk manajemen yang efektif, terutama pada kasus-kasus kronis. Kesimpulannya adalah manajemen VB dan KVV yang efektif secara bersamaan membutuhkan pemahaman yang komprehensif tentang interaksi keduanya dan strategi pengobatan yang disesuaikan. Penelitian lebih lanjut diperlukan untuk mengeksplorasi mekanisme interaksi ini dan meningkatkan pendekatan terapeutik.
Scabies Risk Factor Analysis in Students at Islamic Boarding School Mawardi, Prasetyadi; Oktavriana , Triasari; Murasmita , Alamanda; Murastami , Ammarilis; Primisawitri , Pratiwi Prasetya; Rosyid , Azhar; Putri , Osdatilla Esa; Pradestine, Sesia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 3 (2024): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.3.2024.168-173

Abstract

Background: Scabies is a highly contagious skin disease that often occurs in densely populated settings, especially among children, including those in boarding schools. Purpose: We aimed to investigate the risk factors for scabies infestation in boarding schools. Methods: This crosssectional analytic research was conducted at the Imam Syuhodo Modern Islamic Boarding School. This study consisted of four main steps: survey questionnaires, a pre-test, one-on-one doctor examination, and a brief discussion. The collected data was analyzed using the ChiSquare test and bivariate analysis. Additional multivariate analysis was performed to determine the most influential risk factors. Result: The total sample for the study was 490 students (242 males and 248 females). The overall prevalence of scabies in the boarding school was 16.12%. Bivariate analysis showed a significant relationship between male sex, age (<14 years), history of itchiness, and sharing belongings. In the multivariate analysis, sex (OR 5.56, 95% CI 2.5911.93) and age (OR 2.09, 95% CI 1.23-3.56) turned out to be the most significant factor for scabies. Dermatology specific quality of life index assessment showed more severe negative effects on students with scabies (p<0.001). Discussion: Scabies prevalence was more common in younger males patients. The prevalence of male students was very disproportionate, which needs further attention when designing an intervention model. Students in boarding schools dealing with scabies have worse impacts on their daily lives, which could impede their academic progress.
Investigating The Impact of Pruritus on The Quality of Life of the Elderly in Surakarta Nursing Home Oktavriana, Triasari; Mawardi, Prasetyadi; Murastami, Ammarilis; Murasmita, Alamanda; Pradestine, Sesia; Putri, Osdatilla Esa; Lidjaja, Lifesia Natali; Alia, Vrenda; Kusumasari, Nila
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1641

Abstract

Background: The elderly population has been growing rapidly in recent decades. Research has shown that the prevalence of itching (pruritus) increases with age, with 20.8% of individuals aged 60-69 years experiencing it, 22.9% for those aged 70-79 years, and 26% for those aged 75 years and above. Assessing the skin's barrier function by measuring transepidermal water loss (TEWL) using a tool called a Tewameter is important for objectively evaluating dry skin, which is the most common cause of itching in the elderly. It's important to understand how itching affects the quality of life of the elderly, particularly in nursing homes. Objective: This study aims to determine how itching affects the quality of life of the elderly in nursing homes in Surakarta City, especially at PMI Peduli and Aisyiyah Nursing Homes. Methods: This research used an observational, cross-sectional design. Data was collected through interviews using the 5D itch scale questionnaire, and the quality of life was measured using the DLQI (Dermatology Life Quality Index) questionnaire. TEWL levels were also measured using a Tewameter. Results: 29 subjects participated in the interviews, with 69% being women and 31% being men. Most subjects were aged 60-69 years (41%), and the most common comorbidity was hypertension (41%). The 5D Itch Scale questionnaire revealed that itching affected the subjects for less than 6 hours daily (66%), and during the last 2 weeks, itching did not significantly impact the subjects' activities, including sleep, hobbies, housework, and work (51%-69%). The most common location of itching was the back (14%). The DLQI data showed that itching had a severe impact on the subjects (65.5%), followed by a moderate impact (24.1%), and a very severe impact (10.3%). TEWL data indicated that all subjects had an increase of >10 g/h/m2. Conclusion: The study found that itching had a mild impact on the lives and activities of the subjects in general, lasting for less than 6 hours a day. The statistical results showed a positive and significant relationship between the intensity of itching and the quality of life of the elderly with pruritus.
Profile of Skin Diseases in The Ederley at Nursing House Surakarta Mawardi, Prasetyadi; Oktavriana, Triasari; Murastami, Ammarilis; Murasmita, Alamanda; Pradestine, Sesia; Esa Putri, Osdatilla Esa; Lidjaja, Lifesia Natali; Alia, Vrenda; Kusumasari, Nila
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1640

Abstract

Background: The elderly population has been rapidly increasing over the past few decades. In Indonesia, the percentage of elderly residents is 8.75% of the total population. Aging is an unavoidable process, but it requires care to ensure a good quality of life for the elderly. One of the issues affecting the quality of life in the elderly is skin aging. Skin aging causes various complaints, especially itching or pruritus, which can reduce the quality of life for the elderly. Knowledge of the pathophysiology of skin diseases and skin aging, as well as the factors that affect them, particularly skin hydration, is necessary. This research is expected to be beneficial for medical professionals as well as family members of the elderly. The elderly residents at Wreda Griya PMI Peduli and Aisyiyah Nursing Home come from various regions and economic backgrounds. Therefore, the researchers consider the nursing home to be an appropriate place to conduct this study, as it can represent the elderly population from diverse backgrounds across Indonesia.Objective: This study aims to analyze the various skin disease profiles at the Griya PMI Peduli and Aisyiyah nursing homes in the city of Surakarta. Methods: This type of research is a survey using an observational study method with a descriptive design. Results: There were a total of 45 subjects at the Wreda PMI Peduli and Aisyiyah Nursing Home in Surakarta. Among them, 34 subjects had skin complaints, while 11 subjects were excluded because they did not have any skin complaints (7 subjects) or were uncooperative (4 subjects). The most common diagnosis was xerosis cutis (53%). The majority of patients did not have comorbidities (65%), with the most common comorbidity being hypertension (26%). Conclusion: The results of this study indicate that all the main skin complaints among the elderly at Panti Wreda in Kota Surakarta were dominated by itching or pruritus, with xerosis cutis being the primary etiology of pruritus in the elderly subjects of the study, accounting for 53%.
Profile And Risk Factors of Stevens Johnson Syndrome–Toxic Epidermal Necrolysis on Adult Patients in Dr. Moewardi General Hospital Surakarta from January 2019 – December 2022 Putri, Osdatilla Esa; Oktavriana, Triasari; Octarica, Stella Gracia; Anandita, Benedikta Lauda; Pradestine, Sesia; Oktaviani, Trya
Health and Medical Journal Vol 6, No 2 (2024): HEME May 2024
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v6i2.1517

Abstract

Background: Steven Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute and life-threatening skin diseases, commonly induced by medications. Study on SJS/TEN in Indonesia was still limited, hence knowledge about the profile and risk factors of SJS/TEN patients is still required to provide appropriate management and reduce patient mortality rate. This study aimed to determine the profile and risk factors of adult SJS/TEN patients in the inpatient installation of RSDM Surakarta. Methods: We conducted a cross sectional study using secondary data from medical records of SJS/TEN patients at the inpatient installation of Dr. Moewardi hospital, Surakarta from 2019 – 2022. Correlation tests on characteristics, comorbidity with length of stay (LoS) and discharge status were analyzed. Results: Of the total 147,531 inpatients, 35 (0.02%) of them were diagnosed with SJS/TEN, dominated by females (57.14%) with the mean  of 45.74 years old.  Most subjects were diagnosed with SJS (48.57%), followed by SJS/TEN (40.0%) and TEN (11.43%). The mean LoS was  ± 8 days. Most subjects were discharged alive (85.71%). Paracetamol was the most common causative drug (25.71%), followed by cefadroxil (11.43%). Acute kidney injury (AKI) was the most common comorbidity (14.29%, p = 0.040). Spearman Rank test obtained no correlation between comorbidities and LoS (r = 0.028 ; p = 0.842) as well as discharge status (r = 0.063 ; p = 0.651). Conclusion: SJS/TEN is rare case with high mortality rate. Patients’ comorbidities have a very weak correlation with LoS and discharge status. Initial knowledge of the patient’s profile and risk factors including comorbidity and causative drugs can optimise comprehensive therapy for SJS/TEN patients.
Co-Authors Alia, Vrenda Anandita, Benedikta Lauda Esa Putri, Osdatilla Esa Lidjaja, Lifesia Natali Murasmita , Alamanda Murasmita, Alamanda Murastami , Ammarilis Murastami, Ammarilis Nila Kusumasari Octarica, Stella Gracia Oktaviani, Trya Oktavriana , Triasari Prasetyadi Mawardi Primisawitri , Pratiwi Prasetya Putri , Osdatilla Esa Putri, Osdatilla Esa Rosyid , Azhar Triasari Oktavriana