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Putri, Osdatilla Esa
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Investigating The Impact of Pruritus on The Quality of Life of the Elderly in Surakarta Nursing Home Oktavriana, Triasari; Mawardi, Prasetyadi; Murastami, Ammarilis; Murasmita, Alamanda; Pradestine, Sesia; Putri, Osdatilla Esa; Lidjaja, Lifesia Natali; Alia, Vrenda; Kusumasari, Nila
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1641

Abstract

Background: The elderly population has been growing rapidly in recent decades. Research has shown that the prevalence of itching (pruritus) increases with age, with 20.8% of individuals aged 60-69 years experiencing it, 22.9% for those aged 70-79 years, and 26% for those aged 75 years and above. Assessing the skin's barrier function by measuring transepidermal water loss (TEWL) using a tool called a Tewameter is important for objectively evaluating dry skin, which is the most common cause of itching in the elderly. It's important to understand how itching affects the quality of life of the elderly, particularly in nursing homes. Objective: This study aims to determine how itching affects the quality of life of the elderly in nursing homes in Surakarta City, especially at PMI Peduli and Aisyiyah Nursing Homes. Methods: This research used an observational, cross-sectional design. Data was collected through interviews using the 5D itch scale questionnaire, and the quality of life was measured using the DLQI (Dermatology Life Quality Index) questionnaire. TEWL levels were also measured using a Tewameter. Results: 29 subjects participated in the interviews, with 69% being women and 31% being men. Most subjects were aged 60-69 years (41%), and the most common comorbidity was hypertension (41%). The 5D Itch Scale questionnaire revealed that itching affected the subjects for less than 6 hours daily (66%), and during the last 2 weeks, itching did not significantly impact the subjects' activities, including sleep, hobbies, housework, and work (51%-69%). The most common location of itching was the back (14%). The DLQI data showed that itching had a severe impact on the subjects (65.5%), followed by a moderate impact (24.1%), and a very severe impact (10.3%). TEWL data indicated that all subjects had an increase of >10 g/h/m2. Conclusion: The study found that itching had a mild impact on the lives and activities of the subjects in general, lasting for less than 6 hours a day. The statistical results showed a positive and significant relationship between the intensity of itching and the quality of life of the elderly with pruritus.
Kelainan Mukokutan dan Infeksi Menular Seksual pada Pasien Anak dengan HIV/AIDS Oktaviani, Trya; Mawardi, Prasetyadi; Putri, Osdatilla Esa; Anandita, Benedikta Lauda
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1628

Abstract

Latar Belakang: Lesi mukokutan dan infeksi menular seksual (IMS) adalah manifestasi umum pada individu yang terinfeksi virus imunodefisiensi manusia (HIV) atau sindrom imunodefisiensi didapat (AIDS). Kelainan mukokutan dan infeksi menular seksual (IMS) pada anak-anak dengan HIV/AIDS dapat muncul dengan gejala atipikal, cenderung lebih parah, dan lebih sulit diobati dibandingkan dengan anak-anak dengan sistem kekebalan yang baik. Tujuan: Penelitian ini dilakukan untuk mengidentifikasi kelainan mukokutan dan infeksi menular seksual (IMS) pada pasien anak dengan HIV/AIDS di Klinik Dermatologi dan Venerologi Rumah Sakit Dr. Moewardi, Surakarta, dari Januari 2020 hingga Desember 2022. Metode: Studi deskriptif retrospektif dilakukan dengan menggunakan data sekunder dari catatan medis pasien anak dengan HIV/AIDS yang mengunjungi poliklinik Dermatologi dan Venerologi di Rumah Sakit Dr. Moewardi, Surakarta, dari 1 Januari 2020 hingga 31 Desember 2022. Hasil: Penelitian ini melibatkan sembilan pasien anak dengan HIV/AIDS, terdiri dari enam laki-laki (67%) dan tiga perempuan (33%). Kelompok usia yang paling banyak diwakili adalah 12-17 tahun, dengan lima pasien (n = 5; 56%). Semua pasien menjalani terapi antiretroviral (ARV) rutin. Manifestasi mukokutan yang paling umum adalah erupsi papular pruritus, diamati pada enam pasien (n = 6; 67%), diikuti oleh dermatitis seboroik dan skrofuloderma, masing-masing mempengaruhi satu pasien (n = 1; 11%). Kondiloma akuminata adalah satu-satunya IMS yang teridentifikasi, hadir pada satu pasien (n = 1; 11%). Tujuh pasien (77%) memiliki jumlah CD4 lebih dari 200 sel/mm³, sedangkan dua pasien (23%) memiliki jumlah CD4 kurang dari 200 sel/mm³. Kesimpulan: Erupsi papular pruritus adalah kondisi mukokutan yang paling umum di antara pasien anak dengan HIV/AIDS, sedangkan kondiloma akuminata adalah IMS yang dominan.
Clinical Manifestations and Prognosis Factors in Severe Cutaneous Adverse Drug Reaction (Scadr) Oktavriana, Triasari; Lauda, Benedikta; Putri, Osdatilla Esa
Jurnal Health Sains Vol. 6 No. 8 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i8.2674

Abstract

Severe Cutaneous adverse drug reaction (SCADR) is a severe skin reaction due to the use of drugs that can be life-threatening. This article describes the clinical manifestations and prognosis factors that affect SCADR patients. The most common types of SCADR were Stevens-Johnson Syndrome (SSJ) and Toxic Epidermal Necrolysis (TEN). The drugs that most often trigger are antibiotics and anticonvulsants. The main clinical manifestations include erythematosa skin lesions, epidermal necrolysis, and mucosal involvement. Significant prognosis factors include the extent of the affected skin area, internal organ involvement, and SCORTEN score. Patients with high SCORTEN scores have a greater risk of mortality. Early treatment and discontinuation of trigger drugs are key factors in improving clinical outcomes. The conclusion is early recognition of clinical manifestations of SCADR as well as assessment of prognosis factors can be helpful in patient management and reduce the risk of serious complications. The study also highlights the importance of educating medical personnel in detecting and managing severe drug reactions.
Maternal Atopy Diathesis on The Newborn’s Skin Acidity and Hydration Putri, Osdatilla Esa; Widhiati, Suci; Mawardi, Prasetyadi; Kusumawardani, Arie; Mulianto, Nurrachmat; Hidayah, Dwi; Endraputra, Pristiawan
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.50222

Abstract

Background: Atopic diathesis, a hereditary predisposition to allergic disorders such as atopic dermatitis, asthma, and allergic rhinitis, is more strongly transmitted maternally. Maternal atopy may influence neonatal skin barrier development, but evidence on its effect on neonatal skin pH and hydration is limited. Methods: This cross-sectional study was conducted at Dr. Moewardi General Hospital, Surakarta, Indonesia, between March–April 2025. Neonates (28–41 weeks gestation), <24 hours old, and delivered by cesarean section were included. Skin pH was measured on the volar forearm and axilla using a calibrated pH meter, and hydration (water and oil content) was assessed with a Skin Tester. Maternal atopy diathesis was classified by the Erlangen Atopy Score (EAS). Results: Twenty-nine neonates were enrolled, comprising 12 with and 17 without maternal atopy. No significant association was found between maternal atopy and neonatal hydration (water: p = 0.460; oil: p = 0.997) or skin pH (p = 0.876). Conclusion: Maternal atopy diathesis was not associated with neonatal skin pH or hydration in the first 24 hours of life. Early neonatal skin physiology appears to be influenced more by intrinsic maturation than maternal atopic status. Longitudinal studies are needed to assess potential delayed effects.
Profile And Risk Factors of Stevens Johnson Syndrome–Toxic Epidermal Necrolysis on Adult Patients in Dr. Moewardi General Hospital Surakarta from January 2019 – December 2022 Putri, Osdatilla Esa; Oktavriana, Triasari; Octarica, Stella Gracia; Anandita, Benedikta Lauda; Pradestine, Sesia; Oktaviani, Trya
Health and Medical Journal Vol 6, No 2 (2024): HEME May 2024
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v6i2.1517

Abstract

Background: Steven Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute and life-threatening skin diseases, commonly induced by medications. Study on SJS/TEN in Indonesia was still limited, hence knowledge about the profile and risk factors of SJS/TEN patients is still required to provide appropriate management and reduce patient mortality rate. This study aimed to determine the profile and risk factors of adult SJS/TEN patients in the inpatient installation of RSDM Surakarta. Methods: We conducted a cross sectional study using secondary data from medical records of SJS/TEN patients at the inpatient installation of Dr. Moewardi hospital, Surakarta from 2019 – 2022. Correlation tests on characteristics, comorbidity with length of stay (LoS) and discharge status were analyzed. Results: Of the total 147,531 inpatients, 35 (0.02%) of them were diagnosed with SJS/TEN, dominated by females (57.14%) with the mean  of 45.74 years old.  Most subjects were diagnosed with SJS (48.57%), followed by SJS/TEN (40.0%) and TEN (11.43%). The mean LoS was  ± 8 days. Most subjects were discharged alive (85.71%). Paracetamol was the most common causative drug (25.71%), followed by cefadroxil (11.43%). Acute kidney injury (AKI) was the most common comorbidity (14.29%, p = 0.040). Spearman Rank test obtained no correlation between comorbidities and LoS (r = 0.028 ; p = 0.842) as well as discharge status (r = 0.063 ; p = 0.651). Conclusion: SJS/TEN is rare case with high mortality rate. Patients’ comorbidities have a very weak correlation with LoS and discharge status. Initial knowledge of the patient’s profile and risk factors including comorbidity and causative drugs can optimise comprehensive therapy for SJS/TEN patients.
Co-Authors Alia, Vrenda Anandita, Benedikta Lauda Dwi Hidayah Endraputra, Pristiawan Kusumawardani, Arie Lauda, Benedikta Lidjaja, Lifesia Natali Murasmita, Alamanda Murastami, Ammarilis Nila Kusumasari Nurrachmat Mulianto Octarica, Stella Gracia Oktaviani, Trya Pradestine, Sesia Prasetyadi Mawardi Triasari Oktavriana Widhiati, Suci