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All Journal Journal Of Vocational Health Studies Indonesian Journal of Cultural and Community Development Shihatuna : Jurnal Pengabdian Kesehatan Masyarakat Proceedings of The ICECRS Eduvest - Journal of Universal Studies Journal of Empowerment and Community Service Journal of Social Comunity Services Journal of Global Research in Public Health Academia Open
Anis Khoirin Hayati
Fakultas Kedokteran Gigi, Universitas Muhammadiyah Sidoarjo
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Inhibition of Propolis on the Growth of Aggregatibacter Actinomycetemcomitans: Daya Hambat Propolis terhadap Pertumbuhan Aggregatibacter Actinomycetemcomitans Novita Pratiwi; Anis Khoirin Hayati; Nurul Maulidah
Academia Open Vol. 10 No. 1 (2025): June
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.10.2025.10589

Abstract

General Background: Periodontitis, a chronic inflammatory disease, leads to tooth loss, with Aggregatibacter actinomycetemcomitans playing a key role in its pathogenesis. Specific Background: The rise of antibiotic resistance necessitates alternative treatments. Propolis, a bee-derived resin, has shown antimicrobial properties. Knowledge Gap: Limited research exists on the inhibitory effects of propolis against A. actinomycetemcomitans at varying concentrations. Aims: This study evaluates the antibacterial activity of propolis extract on A. actinomycetemcomitans in vitro. Results: Propolis exhibited significant antibacterial effects, with a minimum inhibitory concentration of 12.5% (125 mg/mL), attributed to flavonoids and apigenin. Statistical analysis confirmed significant differences across concentrations (p < 0.05). Novelty: This study highlights the concentration-dependent antibacterial efficacy of propolis against A. actinomycetemcomitans, suggesting its potential as a natural therapeutic. Implications: Propolis may serve as a complementary antimicrobial in periodontal therapy, reducing antibiotic reliance and resistance. Highlights: Effective Antibacterial Agent – Propolis inhibits A. actinomycetemcomitans growth at a minimum concentration of 12.5% (125 mg/mL). Bioactive Components – Flavonoids and apigenin in propolis disrupt bacterial membranes and biofilm formation. Clinical Potential – Propolis may serve as a natural alternative to antibiotics in periodontal therapy. Keywords: Periodontitist, Propolis, Aggregatibacter Actinomycetemcomitans, Antimicroba
Chlorhexidine Mouthwash Use and Blood Glucose Trends by Age and Gender: Penggunaan Obat Kumur Klorheksidin dan Tren Glukosa Darah Berdasarkan Usia dan Jenis Kelamin Dwi Wahyu Indrawati; Lely Ika Mariyati; Andika Aliviameita; Anis Khoirin Hayati; Paramitha Amelia Kusumawardani
Academia Open Vol. 10 No. 1 (2025): June
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.10.2025.11385

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General Background: Oral health is intricately associated with systemic health, particularly in the aging population where chronic conditions such as diabetes are prevalent. Specific Background: Chlorhexidine 0.2% mouthwash is widely used to reduce oral microbial load, potentially influencing systemic inflammation and metabolic markers. Knowledge Gap: However, the systemic impact of routine chlorhexidine use, especially on glycemic regulation in older adults, remains insufficiently explored. Aims: This cross-sectional study aimed to evaluate the association between the use of 0.2% chlorhexidine mouthwash and random blood glucose (RBG) levels, while considering age and gender influences. Results: Among 90 respondents, predominantly aged ≥40 years (82%), 34% reported regular chlorhexidine use. Users showed a lower mean RBG (120 mg/dL) compared to non-users (128 mg/dL), though the difference was not statistically significant (p > 0.05). Gender-based analysis also revealed no significant differences. Novelty: This study contributes novel insight by highlighting a possible, albeit non-significant, trend toward improved glycemic status in chlorhexidine users. Implications: While not conclusive, these findings suggest that consistent oral hygiene via chlorhexidine may support systemic health maintenance in older adults, reinforcing the need for longitudinal studies on its metabolic effects. Highlights: Highlights a potential link between oral hygiene and blood glucose control. Shows lower average glucose in chlorhexidine users, though not significant. Supports further research on systemic benefits of mouthwash use in elderly. Keywords: Chlorhexidine 0.2%, Blood Glucose, Oral Health, Aging Population, Cross-Sectional Study
Co-Authors Adi, Ali Agus Hayatal Falah Amelia, Ananda Firly Amri, Rangga Nur Zaifatul Andika Aliviameita Davinaiella R G Prameswari Dedi Fardiaz Dwi wahyu indrawati Ernie Maduratna Setyawatie Faisal Hamdi Febrianti , Sofi Intan Hasan, Salma Tsaniyah El Hidayah, Pratiwi Nur Imaniah, Anissa Alifia Indah Dwi Lestari Joni Haryanto Kartika, Mas Aldrin Zagna Rania Lely Ika Mariyati Maulidah, Nurul Muhammad Rizky Akbar Manurung Nihayah, Durrotun Novita Pratiwi Nurul Maulidah Ornando, Muhammad Athallah Hazel Paramitha Amelia Kusumawardani Pratiwi, Novita Rafhani Rosyidah Ratna Wardhani Retno Pudji Rahayu Rizky Briliant Syah Manurung Rizky Briliant Syah Manurung Salma Tsaniyah Sandu Siyoto, Sandu Sandy, Rizky Rahmahdian Sari, Ervina Fatika Silmi , Dewi Nurus Syahfitri , Aisah Aprillia Syavitri , Nadiya Ami Yunita Wulandari Zulyansah , Moch. Firnanda